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The map label for this gene is moaE [H]

Identifier: 212224771

GI number: 212224771

Start: 1480028

End: 1480456

Strand: Reverse

Name: moaE [H]

Synonym: TON_1620

Alternate gene names: 212224771

Gene position: 1480456-1480028 (Counterclockwise)

Preceding gene: 212224773

Following gene: 212224770

Centisome position: 80.13

GC content: 49.18

Gene sequence:

>429_bases
ATGAAGGTTAAGATTACTAAAGAACCCTTCGATCTCAATGAGGCGTTGAGTTATCTTCTCGTTCCAGAGGCCGGTGGCTA
CGTTTTCTTCTTGGGGAAGGTCAGGAACGAAAACCATGGCAGAAAAGTCAGAAAACTCATCTACGAGGCCTATGAAGAGA
TGGCCATTGAAGAGATGGAGAGGATACGGGGAGAAGCACTTGAAAAGTTTCCCATATTGGACATCCTGATATGGCACCGC
TACGGCGAGCTCAACGTGGGCGAGGACACGATACTCATTATTGCCAGTGGCAAGCACAGGAAGGAGGCATTTGAGGCCTG
TATGTGGGCAATCGACGAGGTCAAGAGGCGCGTCCCGGTTTGGAAACGTGAGGTGACTGATGAGGGTATCTTCTGGATTG
AGGGTGATAAGCTTATACCTGACGAATGA

Upstream 100 bases:

>100_bases
TTCCATTCACCGACAACCCCTGAGCTTGAAACCACTTAAACCTTTTTATTAGCCCGACAGATTTAATTGGGTGAAGCTTT
AAGTTCCATGGGGGATGGAT

Downstream 100 bases:

>100_bases
ACATTTATGTTCTCTCCATTTTTTGCTAACTATTATTAGTAGTATGCAAAATCGGAATAGAAAAAGTATATATACAATTT
TGTCCCATTCTCGGTCGGTG

Product: molybdopterin converting factor, subunit 2

Products: NA

Alternate protein names: MPT synthase subunit 2; Molybdenum cofactor biosynthesis protein E; Molybdopterin-converting factor large subunit; Molybdopterin-converting factor subunit 2 [H]

Number of amino acids: Translated: 142; Mature: 142

Protein sequence:

>142_residues
MKVKITKEPFDLNEALSYLLVPEAGGYVFFLGKVRNENHGRKVRKLIYEAYEEMAIEEMERIRGEALEKFPILDILIWHR
YGELNVGEDTILIIASGKHRKEAFEACMWAIDEVKRRVPVWKREVTDEGIFWIEGDKLIPDE

Sequences:

>Translated_142_residues
MKVKITKEPFDLNEALSYLLVPEAGGYVFFLGKVRNENHGRKVRKLIYEAYEEMAIEEMERIRGEALEKFPILDILIWHR
YGELNVGEDTILIIASGKHRKEAFEACMWAIDEVKRRVPVWKREVTDEGIFWIEGDKLIPDE
>Mature_142_residues
MKVKITKEPFDLNEALSYLLVPEAGGYVFFLGKVRNENHGRKVRKLIYEAYEEMAIEEMERIRGEALEKFPILDILIWHR
YGELNVGEDTILIIASGKHRKEAFEACMWAIDEVKRRVPVWKREVTDEGIFWIEGDKLIPDE

Specific function: Converts molybdopterin precursor Z into molybdopterin. This requires the incorporation of two sulfur atoms into precursor Z to generate a dithiolene group. The sulfur is provided by moaD [H]

COG id: COG0314

COG function: function code H; Molybdopterin converting factor, large subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the moaE family [H]

Homologues:

Organism=Homo sapiens, GI4758732, Length=135, Percent_Identity=36.2962962962963, Blast_Score=99, Evalue=1e-21,
Organism=Escherichia coli, GI1787003, Length=136, Percent_Identity=36.7647058823529, Blast_Score=92, Evalue=2e-20,
Organism=Caenorhabditis elegans, GI17509279, Length=128, Percent_Identity=31.25, Blast_Score=74, Evalue=2e-14,
Organism=Drosophila melanogaster, GI21356259, Length=126, Percent_Identity=38.8888888888889, Blast_Score=99, Evalue=1e-21,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003448 [H]

Pfam domain/function: PF02391 MoaE [H]

EC number: NA

Molecular weight: Translated: 16682; Mature: 16682

Theoretical pI: Translated: 4.97; Mature: 4.97

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKVKITKEPFDLNEALSYLLVPEAGGYVFFLGKVRNENHGRKVRKLIYEAYEEMAIEEME
CEEEECCCCCCHHHHHHEEECCCCCCEEEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHH
RIRGEALEKFPILDILIWHRYGELNVGEDTILIIASGKHRKEAFEACMWAIDEVKRRVPV
HHHHHHHHHCCHHHHHEECCCCCCCCCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHCCH
WKREVTDEGIFWIEGDKLIPDE
HHHHCCCCCEEEEECCEECCCC
>Mature Secondary Structure
MKVKITKEPFDLNEALSYLLVPEAGGYVFFLGKVRNENHGRKVRKLIYEAYEEMAIEEME
CEEEECCCCCCHHHHHHEEECCCCCCEEEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHH
RIRGEALEKFPILDILIWHRYGELNVGEDTILIIASGKHRKEAFEACMWAIDEVKRRVPV
HHHHHHHHHCCHHHHHEECCCCCCCCCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHCCH
WKREVTDEGIFWIEGDKLIPDE
HHHHCCCCCEEEEECCEECCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12622808 [H]