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The map label for this gene is moeB [H]

Identifier: 212224773

GI number: 212224773

Start: 1481421

End: 1482119

Strand: Reverse

Name: moeB [H]

Synonym: TON_1622

Alternate gene names: 212224773

Gene position: 1482119-1481421 (Counterclockwise)

Preceding gene: 212224774

Following gene: 212224771

Centisome position: 80.22

GC content: 53.08

Gene sequence:

>699_bases
ATGCTGAGCGAGAGGGAACTGGAGCGCTACGACAGACAGATCATGATTTTCGGAAAGGAAGGTCAGGAAAAGCTCAAGAA
CTCCAAGGTGGCTGTGGTAGGAGTAGGCGGTCTTGGAAGTCCGGTCGCCTACTACCTTGCTGCCGCTGGAATAGGGACGC
TCCTCCTCATAGACGAGCAGACACCCGAGCTCAGCAACCTCAACAGGCAGGTACTCCACTGGGAGGAGGATTTGGATAAG
AACTCCAAACCGATCTCCGCCAAATGGAAGCTGGAACGCTTCAACTCCGACATAAAAATCGAGACCTTCGTGGGACGTCT
AAGTGAGGAGAACATCGATGAGATTCTCGAAGGCGTTGAGGTAATCGTTGACTGCCTCGACAACTTCGAGACGCGCTTCC
TTCTCGATGACTATGCGCAGAGGAAGAAAATCCCCCTCGTCCATGGCGCGGTCGAAGGAACCTACGGTCAGGTGACGACG
ATAGTTCCGGGCTTCACCAAAAGCCTGCGCGAAATCTTTCCAAACGTAGGGAGAAAGAAGGAGAAGTTCCCGATTTTAGG
AGCTACCGCGGGGGTCATCGGCACGCTTCAGGCAATGGAGGTCGTTAAGCTACTCACAGGCATCGGCGAGCCGCTATTGA
ACAAGCTTCTCATAGTTGATCTGGCCTTCAACACCTTTGATGTCGTGGAGCTTAAGTAG

Upstream 100 bases:

>100_bases
GACGTCAACGTTTCGCGGAACGGGCGCTATGTGAGCTTCGACGAGGTTTTGAATGACGGTGACACGATAGCGCTGTTCCC
CCCGGTAAGTGGTGGTTGAT

Downstream 100 bases:

>100_bases
AGGGCTCCTTCACGCTTTTCTTTTCGTTGATGCTCTTTATCTCGATGACCTCGTTCCAGGATCCCTCCTGGGTTATCGTC
ATGGTGCCGAGCATTGGGTC

Product: protein

Products: NA

Alternate protein names: MoaD protein adenylase; Molybdopterin-converting factor subunit 1 adenylase [H]

Number of amino acids: Translated: 232; Mature: 232

Protein sequence:

>232_residues
MLSERELERYDRQIMIFGKEGQEKLKNSKVAVVGVGGLGSPVAYYLAAAGIGTLLLIDEQTPELSNLNRQVLHWEEDLDK
NSKPISAKWKLERFNSDIKIETFVGRLSEENIDEILEGVEVIVDCLDNFETRFLLDDYAQRKKIPLVHGAVEGTYGQVTT
IVPGFTKSLREIFPNVGRKKEKFPILGATAGVIGTLQAMEVVKLLTGIGEPLLNKLLIVDLAFNTFDVVELK

Sequences:

>Translated_232_residues
MLSERELERYDRQIMIFGKEGQEKLKNSKVAVVGVGGLGSPVAYYLAAAGIGTLLLIDEQTPELSNLNRQVLHWEEDLDK
NSKPISAKWKLERFNSDIKIETFVGRLSEENIDEILEGVEVIVDCLDNFETRFLLDDYAQRKKIPLVHGAVEGTYGQVTT
IVPGFTKSLREIFPNVGRKKEKFPILGATAGVIGTLQAMEVVKLLTGIGEPLLNKLLIVDLAFNTFDVVELK
>Mature_232_residues
MLSERELERYDRQIMIFGKEGQEKLKNSKVAVVGVGGLGSPVAYYLAAAGIGTLLLIDEQTPELSNLNRQVLHWEEDLDK
NSKPISAKWKLERFNSDIKIETFVGRLSEENIDEILEGVEVIVDCLDNFETRFLLDDYAQRKKIPLVHGAVEGTYGQVTT
IVPGFTKSLREIFPNVGRKKEKFPILGATAGVIGTLQAMEVVKLLTGIGEPLLNKLLIVDLAFNTFDVVELK

Specific function: Catalyzes the adenylation by ATP of the carboxyl group of the C-terminal glycine of sulfur carrier protein moaD [H]

COG id: COG0476

COG function: function code H; Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the hesA/moeB/thiF family [H]

Homologues:

Organism=Homo sapiens, GI7657339, Length=226, Percent_Identity=37.1681415929204, Blast_Score=122, Evalue=4e-28,
Organism=Homo sapiens, GI23510338, Length=169, Percent_Identity=29.585798816568, Blast_Score=78, Evalue=8e-15,
Organism=Homo sapiens, GI23510340, Length=169, Percent_Identity=29.585798816568, Blast_Score=78, Evalue=8e-15,
Organism=Homo sapiens, GI150417996, Length=171, Percent_Identity=31.5789473684211, Blast_Score=70, Evalue=2e-12,
Organism=Homo sapiens, GI38045948, Length=168, Percent_Identity=28.5714285714286, Blast_Score=65, Evalue=7e-11,
Organism=Escherichia coli, GI1787048, Length=237, Percent_Identity=35.8649789029536, Blast_Score=138, Evalue=4e-34,
Organism=Escherichia coli, GI87082356, Length=216, Percent_Identity=36.1111111111111, Blast_Score=132, Evalue=3e-32,
Organism=Escherichia coli, GI1789177, Length=204, Percent_Identity=25.4901960784314, Blast_Score=71, Evalue=6e-14,
Organism=Caenorhabditis elegans, GI17540406, Length=228, Percent_Identity=35.9649122807018, Blast_Score=136, Evalue=7e-33,
Organism=Caenorhabditis elegans, GI86565433, Length=180, Percent_Identity=31.1111111111111, Blast_Score=76, Evalue=2e-14,
Organism=Caenorhabditis elegans, GI86565431, Length=180, Percent_Identity=31.1111111111111, Blast_Score=75, Evalue=2e-14,
Organism=Caenorhabditis elegans, GI193203301, Length=151, Percent_Identity=29.1390728476821, Blast_Score=68, Evalue=3e-12,
Organism=Caenorhabditis elegans, GI71984476, Length=181, Percent_Identity=30.3867403314917, Blast_Score=68, Evalue=4e-12,
Organism=Saccharomyces cerevisiae, GI6321903, Length=216, Percent_Identity=37.037037037037, Blast_Score=125, Evalue=7e-30,
Organism=Saccharomyces cerevisiae, GI6322639, Length=171, Percent_Identity=31.5789473684211, Blast_Score=80, Evalue=2e-16,
Organism=Saccharomyces cerevisiae, GI6320598, Length=183, Percent_Identity=27.8688524590164, Blast_Score=70, Evalue=2e-13,
Organism=Drosophila melanogaster, GI24582879, Length=242, Percent_Identity=38.8429752066116, Blast_Score=152, Evalue=1e-37,
Organism=Drosophila melanogaster, GI28573937, Length=168, Percent_Identity=35.7142857142857, Blast_Score=88, Evalue=6e-18,
Organism=Drosophila melanogaster, GI24660640, Length=170, Percent_Identity=32.3529411764706, Blast_Score=69, Evalue=2e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR007901
- InterPro:   IPR009036
- InterPro:   IPR012730
- InterPro:   IPR016040
- InterPro:   IPR000594 [H]

Pfam domain/function: PF05237 MoeZ_MoeB; PF00899 ThiF [H]

EC number: NA

Molecular weight: Translated: 25875; Mature: 25875

Theoretical pI: Translated: 4.82; Mature: 4.82

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
1.7 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
1.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLSERELERYDRQIMIFGKEGQEKLKNSKVAVVGVGGLGSPVAYYLAAAGIGTLLLIDEQ
CCCHHHHHHCCCEEEEECCCCHHHHCCCCEEEEEECCCCHHHHHHHHHHCCCEEEEEECC
TPELSNLNRQVLHWEEDLDKNSKPISAKWKLERFNSDIKIETFVGRLSEENIDEILEGVE
CCCHHCCCHHHHHHHHHCCCCCCCCCCEEEHHHCCCCCEEHHHHHHHCCCCHHHHHHHHH
VIVDCLDNFETRFLLDDYAQRKKIPLVHGAVEGTYGQVTTIVPGFTKSLREIFPNVGRKK
HHHHHHHCCCHHHHHHHHHHHCCCCEEECCCCCCCCCEEEECCHHHHHHHHHHHCCCCCC
EKFPILGATAGVIGTLQAMEVVKLLTGIGEPLLNKLLIVDLAFNTFDVVELK
CCCCEEECHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHEEEECCCEEEEEEC
>Mature Secondary Structure
MLSERELERYDRQIMIFGKEGQEKLKNSKVAVVGVGGLGSPVAYYLAAAGIGTLLLIDEQ
CCCHHHHHHCCCEEEEECCCCHHHHCCCCEEEEEECCCCHHHHHHHHHHCCCEEEEEECC
TPELSNLNRQVLHWEEDLDKNSKPISAKWKLERFNSDIKIETFVGRLSEENIDEILEGVE
CCCHHCCCHHHHHHHHHCCCCCCCCCCEEEHHHCCCCCEEHHHHHHHCCCCHHHHHHHHH
VIVDCLDNFETRFLLDDYAQRKKIPLVHGAVEGTYGQVTTIVPGFTKSLREIFPNVGRKK
HHHHHHHCCCHHHHHHHHHHHCCCCEEECCCCCCCCCEEEECCHHHHHHHHHHHCCCCCC
EKFPILGATAGVIGTLQAMEVVKLLTGIGEPLLNKLLIVDLAFNTFDVVELK
CCCCEEECHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHEEEECCCEEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]