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The map label for this gene is gufA [H]

Identifier: 212224496

GI number: 212224496

Start: 1216379

End: 1217188

Strand: Reverse

Name: gufA [H]

Synonym: TON_1345

Alternate gene names: 212224496

Gene position: 1217188-1216379 (Counterclockwise)

Preceding gene: 212224498

Following gene: 212224493

Centisome position: 65.88

GC content: 53.46

Gene sequence:

>810_bases
GTGTTAGACAACTTCATCTCGAACCTCGCCGAATGGATGCTCGAGATCTCCGGGGGCAGCATCCTGTGGGTCTCCTTCTA
TGCGGGCCTTTTTGTGGCTATCATGACCTCTCTCGGCGCGATGGTGGCAATATTCGCCAAGAACATCCCTGAAAGGGGAG
TTGACTTCAGCCTGAGCTTTGCGGCTGGAGTTATGATAGTCGCGAGCTTCACCAGCTTAATTCTCCCTGCTATAGAAAGC
ACCGGGGGCTTTGGGCCGGCTGGAATTGGAATAGCCCTTGGCATTCTCGTGATCTCCGTGATAGACCGCCTCATCCCCCA
CGAGCACATGGTCAAGGGCTACGAAGGCCCAAGCGATTTGAAAGATAGGCTCCGGAAGGTCTGGCTCCTCGTTCTCGCCC
TCATAATCCACAACCTGCCAGAGGGATTAGCCGTTGGTACTTCTCTAGTTTACAACCTTGAGGTTGGCCTAGTTACGGCC
ATCGCTATAGGCATCCAGGACTTCCCTGAAGGGACTGTCGTCTCGCTCCCTCTAGCCGTCATTCAGAAAAAGCGCCTCCA
ACCGATTATGATCGGTGTTCTGAGCGGGTTGGCTGAGATGGCGATGGTAATCCTCGGAGCGATCTTTTTCACGGCCTTTG
CTTGGTCTCTGCCCTACGGCCTTGGGTTGGCAGGAGGGGCCATGCTCTACGTAACTGTGAAGGAGATGATTCCTGAGATA
TATAGGAGAGAAGAAAACGAGACGCTTGTAACTCTGGGCTTCTTCGTTGGATTCTACGTGATGCTCTTCCTCGACTCAAT
GCTCGGCTAA

Upstream 100 bases:

>100_bases
GTAAGCCTCAACTTCAACTTCCTCGAACATATTCCCACCGTCACCCACTCGACCCAAAGCTTATAAAGGCAACCCCCCTA
TTAATTAGGGTGGCCTAACA

Downstream 100 bases:

>100_bases
AATCTTCTCAACGAGCTCCTGAACTCTTCTTTCGTATTCTTCCTTCGGGCAGTCGTTGACTATCATGTAGTCGGCCATTG
CTATGACGTTTCCGATGCCG

Product: heavy-metal cation transporter

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 269; Mature: 269

Protein sequence:

>269_residues
MLDNFISNLAEWMLEISGGSILWVSFYAGLFVAIMTSLGAMVAIFAKNIPERGVDFSLSFAAGVMIVASFTSLILPAIES
TGGFGPAGIGIALGILVISVIDRLIPHEHMVKGYEGPSDLKDRLRKVWLLVLALIIHNLPEGLAVGTSLVYNLEVGLVTA
IAIGIQDFPEGTVVSLPLAVIQKKRLQPIMIGVLSGLAEMAMVILGAIFFTAFAWSLPYGLGLAGGAMLYVTVKEMIPEI
YRREENETLVTLGFFVGFYVMLFLDSMLG

Sequences:

>Translated_269_residues
MLDNFISNLAEWMLEISGGSILWVSFYAGLFVAIMTSLGAMVAIFAKNIPERGVDFSLSFAAGVMIVASFTSLILPAIES
TGGFGPAGIGIALGILVISVIDRLIPHEHMVKGYEGPSDLKDRLRKVWLLVLALIIHNLPEGLAVGTSLVYNLEVGLVTA
IAIGIQDFPEGTVVSLPLAVIQKKRLQPIMIGVLSGLAEMAMVILGAIFFTAFAWSLPYGLGLAGGAMLYVTVKEMIPEI
YRREENETLVTLGFFVGFYVMLFLDSMLG
>Mature_269_residues
MLDNFISNLAEWMLEISGGSILWVSFYAGLFVAIMTSLGAMVAIFAKNIPERGVDFSLSFAAGVMIVASFTSLILPAIES
TGGFGPAGIGIALGILVISVIDRLIPHEHMVKGYEGPSDLKDRLRKVWLLVLALIIHNLPEGLAVGTSLVYNLEVGLVTA
IAIGIQDFPEGTVVSLPLAVIQKKRLQPIMIGVLSGLAEMAMVILGAIFFTAFAWSLPYGLGLAGGAMLYVTVKEMIPEI
YRREENETLVTLGFFVGFYVMLFLDSMLG

Specific function: Mediates Zinc Uptake. May Also Transport Other Divalent Cations Such As Copper And Cadmium Ions. [C]

COG id: COG0428

COG function: function code P; Predicted divalent heavy-metal cations transporter

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Homo sapiens, GI229577422, Length=152, Percent_Identity=40.1315789473684, Blast_Score=89, Evalue=5e-18,
Organism=Homo sapiens, GI229577418, Length=152, Percent_Identity=40.1315789473684, Blast_Score=89, Evalue=6e-18,
Organism=Escherichia coli, GI1789419, Length=244, Percent_Identity=29.9180327868852, Blast_Score=82, Evalue=4e-17,
Organism=Caenorhabditis elegans, GI17507805, Length=321, Percent_Identity=32.0872274143302, Blast_Score=132, Evalue=1e-31,
Organism=Drosophila melanogaster, GI24652846, Length=154, Percent_Identity=38.3116883116883, Blast_Score=96, Evalue=4e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003689 [H]

Pfam domain/function: PF02535 Zip [H]

EC number: NA

Molecular weight: Translated: 28933; Mature: 28933

Theoretical pI: Translated: 4.58; Mature: 4.58

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
4.8 %Met     (Translated Protein)
4.8 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
4.8 %Met     (Mature Protein)
4.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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HCCCCCCEEEHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure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HCCCCCCEEEHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 7934835 [H]