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The map label for this gene is 212224490

Identifier: 212224490

GI number: 212224490

Start: 1211441

End: 1212202

Strand: Reverse

Name: 212224490

Synonym: TON_1339

Alternate gene names: NA

Gene position: 1212202-1211441 (Counterclockwise)

Preceding gene: 212224491

Following gene: 212224488

Centisome position: 65.61

GC content: 52.49

Gene sequence:

>762_bases
TTGATTCGGGAGGGGGATAAGGTACTGCTGATAGATAGGAGGGGGAAGAGGTACCTCGTAACGGTCTCGAATAGGGAGTT
CCACACGGATTTGGGTATAATCAACCTTGGGGAGCTTCTCAATAAGAGCTATGGAGACACCCTGACCAGCCACAAGGGTG
AGGAGTTCAAGATACTGAAGCCAGACATCAACGACATAATAGCCAAAATGAAACGAGGGCCCCAGATAGTGCATCCCAAG
GACGCGGGAATAATCATAGCCTACGCTGGAATCTCACCGGGAGATACGGTTATAGAGGCCGGCGTTGGCAGTGGAGCGCT
GACGATTTTCCTAGCGAACATCGTCGGCCCGGCCGGCAAGGTTATCAGCTATGAGGTAAGGGAAGACTTCGCCAGGATAG
CTCAGAAGAACGTTGAGCTGGCCGGTTTCTCTGACAGGGTCACGATAAAGCTCAAGAACATTTACGAGGGCATCGATGAG
GACTACGCCGACCACATTGTCCTTGACCTTCCACAGCCCGAGAATGTTCTCCCGCATGCCGTTGAAGTCCTCAGGCCCGG
GGGTTACTTTGTCGCCTACACGCCGTGCATGAACCAGGTTCATCGCTTCTTCCAGGCCCTTCAGGAGTACAGGGATCACT
TCTACAAACCGAGGGTTGTAGAGGTCCTTGTCAGGGAGCACGAGGTCAAGAAGGAGTGCATGAGACCAAAAACAACGATG
CTGGCACACACGGGATACATAACATTCCTTAGAAAGCTGTGA

Upstream 100 bases:

>100_bases
ATTTTAAGCAGGGAGCACGTAGCGATGCTCGAGGAGATGGCCTCGATGGTTTTCTACATATCAAAAGATGGCCTGATAGT
AAAGAAGGGCGGTGAGGCAT

Downstream 100 bases:

>100_bases
GTCCTTCTTCATTGTTCTTCGGGCTCTCTTCCTCAAAGGTCAGATAGGCCAATCCCCCAAATATCACGAGCCCTGCGATG
GCCTGAACCAGGGGGTTTCC

Product: tRNA (1-methyladenosine) methyltransferase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 253; Mature: 253

Protein sequence:

>253_residues
MIREGDKVLLIDRRGKRYLVTVSNREFHTDLGIINLGELLNKSYGDTLTSHKGEEFKILKPDINDIIAKMKRGPQIVHPK
DAGIIIAYAGISPGDTVIEAGVGSGALTIFLANIVGPAGKVISYEVREDFARIAQKNVELAGFSDRVTIKLKNIYEGIDE
DYADHIVLDLPQPENVLPHAVEVLRPGGYFVAYTPCMNQVHRFFQALQEYRDHFYKPRVVEVLVREHEVKKECMRPKTTM
LAHTGYITFLRKL

Sequences:

>Translated_253_residues
MIREGDKVLLIDRRGKRYLVTVSNREFHTDLGIINLGELLNKSYGDTLTSHKGEEFKILKPDINDIIAKMKRGPQIVHPK
DAGIIIAYAGISPGDTVIEAGVGSGALTIFLANIVGPAGKVISYEVREDFARIAQKNVELAGFSDRVTIKLKNIYEGIDE
DYADHIVLDLPQPENVLPHAVEVLRPGGYFVAYTPCMNQVHRFFQALQEYRDHFYKPRVVEVLVREHEVKKECMRPKTTM
LAHTGYITFLRKL
>Mature_253_residues
MIREGDKVLLIDRRGKRYLVTVSNREFHTDLGIINLGELLNKSYGDTLTSHKGEEFKILKPDINDIIAKMKRGPQIVHPK
DAGIIIAYAGISPGDTVIEAGVGSGALTIFLANIVGPAGKVISYEVREDFARIAQKNVELAGFSDRVTIKLKNIYEGIDE
DYADHIVLDLPQPENVLPHAVEVLRPGGYFVAYTPCMNQVHRFFQALQEYRDHFYKPRVVEVLVREHEVKKECMRPKTTM
LAHTGYITFLRKL

Specific function: Unknown

COG id: COG2519

COG function: function code J; tRNA(1-methyladenosine) methyltransferase and related methyltransferases

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the methyltransferase superfamily. TRM61 family [H]

Homologues:

Organism=Homo sapiens, GI222831587, Length=214, Percent_Identity=31.7757009345794, Blast_Score=109, Evalue=3e-24,
Organism=Homo sapiens, GI123173772, Length=281, Percent_Identity=25.2669039145907, Blast_Score=89, Evalue=3e-18,
Organism=Caenorhabditis elegans, GI17509459, Length=211, Percent_Identity=26.5402843601896, Blast_Score=82, Evalue=4e-16,
Organism=Saccharomyces cerevisiae, GI6322336, Length=261, Percent_Identity=24.904214559387, Blast_Score=68, Evalue=1e-12,
Organism=Drosophila melanogaster, GI24650257, Length=213, Percent_Identity=29.1079812206573, Blast_Score=90, Evalue=1e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014816 [H]

Pfam domain/function: PF08704 GCD14 [H]

EC number: =2.1.1.36 [H]

Molecular weight: Translated: 28574; Mature: 28574

Theoretical pI: Translated: 8.22; Mature: 8.22

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIREGDKVLLIDRRGKRYLVTVSNREFHTDLGIINLGELLNKSYGDTLTSHKGEEFKILK
CCCCCCEEEEEECCCCEEEEEECCCCEECCCCEEEHHHHHCCCCCCHHHCCCCCCEEEEC
PDINDIIAKMKRGPQIVHPKDAGIIIAYAGISPGDTVIEAGVGSGALTIFLANIVGPAGK
CCHHHHHHHHHCCCCEECCCCCCEEEEECCCCCCCCEEECCCCCCHHHHHHHHHCCCCCC
VISYEVREDFARIAQKNVELAGFSDRVTIKLKNIYEGIDEDYADHIVLDLPQPENVLPHA
EEEEHHHHHHHHHHHCCCEEECCCCEEEEEEHHHHCCCCCCCCCEEEEECCCCCCCCHHH
VEVLRPGGYFVAYTPCMNQVHRFFQALQEYRDHFYKPRVVEVLVREHEVKKECMRPKTTM
HHHHCCCCEEEEECHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCCHHH
LAHTGYITFLRKL
HHHHHHHHHHHCC
>Mature Secondary Structure
MIREGDKVLLIDRRGKRYLVTVSNREFHTDLGIINLGELLNKSYGDTLTSHKGEEFKILK
CCCCCCEEEEEECCCCEEEEEECCCCEECCCCEEEHHHHHCCCCCCHHHCCCCCCEEEEC
PDINDIIAKMKRGPQIVHPKDAGIIIAYAGISPGDTVIEAGVGSGALTIFLANIVGPAGK
CCHHHHHHHHHCCCCEECCCCCCEEEEECCCCCCCCEEECCCCCCHHHHHHHHHCCCCCC
VISYEVREDFARIAQKNVELAGFSDRVTIKLKNIYEGIDEDYADHIVLDLPQPENVLPHA
EEEEHHHHHHHHHHHCCCEEECCCCEEEEEEHHHHCCCCCCCCCEEEEECCCCCCCCHHH
VEVLRPGGYFVAYTPCMNQVHRFFQALQEYRDHFYKPRVVEVLVREHEVKKECMRPKTTM
HHHHCCCCEEEEECHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCCHHH
LAHTGYITFLRKL
HHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]