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The map label for this gene is yceE [C]

Identifier: 212224428

GI number: 212224428

Start: 1162513

End: 1163751

Strand: Reverse

Name: yceE [C]

Synonym: TON_1279

Alternate gene names: 212224428

Gene position: 1163751-1162513 (Counterclockwise)

Preceding gene: 212224429

Following gene: 212224413

Centisome position: 62.99

GC content: 55.61

Gene sequence:

>1239_bases
ATGAGCAGAAGGGAGCTCGTCGTAACGCAGGGGAGGCGCGAGAAGGCAGGGAAGATTCGCAGAATAAGGATCAAGCGCAG
GAACGTGGTCCTGCTAGCGGTGAGTATGTTCATCGCCAACGCGGCCTTTGGCATGGCGTTTCCATATCTCAGCGTCTATA
TGAAGCTCCTCGGCGGCGGCATGCTGATGGTCGGGCTTTTAAGTGTCGCCTTCAACCTGACCTCGACAGTCTTCCAGTAT
CCCTTTGGCTATCTCTCCGATAGGACTAGGAACAGGAAGGCTTTCATATCCTTCGGCCTGTTCTCTACGGGGACCTTCTA
TGCCCTCATGGCTGTCGTTTCAACTCCGTTAGCCCTGCTTACCCTGAGGACGTTCCAGGGAGCACTCGGCTCAGCCATTA
TGCCTGCCCATTCGGCGCTGATAGCGGAGCTCTCGACCCGTGTTGGTTCAGCCTACGGGCTCTTCGGTTCGATTGAGAAC
GCGGGCTACATGCTGGGCAACTTCATCGGCGGCTTCCTTATAAAATACGTCGGGATCAGGGGAATCTTCCTCATAGCAGG
GGCTCTCCTCGTCCTTTCCTCTGCGATAGTTCTCCTCCTCAGGGAGAGGCCGAGGCCGAAAAGGGCTCCAAGAAAGCTTA
TACTCGTCCAGGAAGGGCGGGAAAGCGAGAGGGCAACCTTCCAGGGTGCGGCATTCAAGCGGCTCATGAGGGGCCATCTG
GGCCTTTTCTACTTTACAGTTCTGCTCGTAATGATAGCTTCAGGTCAGGTCTATTCAGTGGTCTCGGTTTACTTTGAGGA
GGTCTTTGGGAGCGAGTGGGTAGGGATACTTTTTGGAATAGACTCTTTAGCGGCGGCGGTGAGCGGATACTACCTCGGGA
AGCTGATTGACCGCTACGGCGCCAAGAAATTCTACCTGCTGGCGATAGCCGGCTACGCCATCGCTTTCCTCGGCTACGCT
TTCGCGAAGAATCTCTACCTGATGATCGTCGTGGCCCTCTTTTCGGGCGTCAAGTGGTCACTGACCCTAAACGCCTCCTC
GACCTATGTTGCCACGAAGGTCAGAGCGACGGAGAGGGGTCAGGCTATGGGCCTGCTCAACGCTATGATGAGCCTCGGCT
GGGTCGTAGGTCCATTACTCGGAGGCTATCTCTCTGCCATAAGCTTTGAGCTGAACTTCATGAGCACGCTCGTGCCTCTC
GGAGTAGCTTTCCTCTTCGCGCTTAGACTTCCAGAGTGA

Upstream 100 bases:

>100_bases
TGAAGAGAGAACCATCGAGATGCTTCAGCGCCATAATAAATCCTCAGCCTAAAATCACCTTGGAGGAAGTTTTATAAGAG
GCTTCCCATAGGCGCGAGCG

Downstream 100 bases:

>100_bases
TGCACTCCGGTGGGACTTTCTCGACTATCCTGACGTTCTTCCCGGCTTTGTAAACCTTCAAGCCTTTCTTTCGGAGGCAT
TCGGCGTCTATTACCAGAAG

Product: multidrug-efflux transporter

Products: Proton [Cytoplasm]; drug [Periplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 412; Mature: 411

Protein sequence:

>412_residues
MSRRELVVTQGRREKAGKIRRIRIKRRNVVLLAVSMFIANAAFGMAFPYLSVYMKLLGGGMLMVGLLSVAFNLTSTVFQY
PFGYLSDRTRNRKAFISFGLFSTGTFYALMAVVSTPLALLTLRTFQGALGSAIMPAHSALIAELSTRVGSAYGLFGSIEN
AGYMLGNFIGGFLIKYVGIRGIFLIAGALLVLSSAIVLLLRERPRPKRAPRKLILVQEGRESERATFQGAAFKRLMRGHL
GLFYFTVLLVMIASGQVYSVVSVYFEEVFGSEWVGILFGIDSLAAAVSGYYLGKLIDRYGAKKFYLLAIAGYAIAFLGYA
FAKNLYLMIVVALFSGVKWSLTLNASSTYVATKVRATERGQAMGLLNAMMSLGWVVGPLLGGYLSAISFELNFMSTLVPL
GVAFLFALRLPE

Sequences:

>Translated_412_residues
MSRRELVVTQGRREKAGKIRRIRIKRRNVVLLAVSMFIANAAFGMAFPYLSVYMKLLGGGMLMVGLLSVAFNLTSTVFQY
PFGYLSDRTRNRKAFISFGLFSTGTFYALMAVVSTPLALLTLRTFQGALGSAIMPAHSALIAELSTRVGSAYGLFGSIEN
AGYMLGNFIGGFLIKYVGIRGIFLIAGALLVLSSAIVLLLRERPRPKRAPRKLILVQEGRESERATFQGAAFKRLMRGHL
GLFYFTVLLVMIASGQVYSVVSVYFEEVFGSEWVGILFGIDSLAAAVSGYYLGKLIDRYGAKKFYLLAIAGYAIAFLGYA
FAKNLYLMIVVALFSGVKWSLTLNASSTYVATKVRATERGQAMGLLNAMMSLGWVVGPLLGGYLSAISFELNFMSTLVPL
GVAFLFALRLPE
>Mature_411_residues
SRRELVVTQGRREKAGKIRRIRIKRRNVVLLAVSMFIANAAFGMAFPYLSVYMKLLGGGMLMVGLLSVAFNLTSTVFQYP
FGYLSDRTRNRKAFISFGLFSTGTFYALMAVVSTPLALLTLRTFQGALGSAIMPAHSALIAELSTRVGSAYGLFGSIENA
GYMLGNFIGGFLIKYVGIRGIFLIAGALLVLSSAIVLLLRERPRPKRAPRKLILVQEGRESERATFQGAAFKRLMRGHLG
LFYFTVLLVMIASGQVYSVVSVYFEEVFGSEWVGILFGIDSLAAAVSGYYLGKLIDRYGAKKFYLLAIAGYAIAFLGYAF
AKNLYLMIVVALFSGVKWSLTLNASSTYVATKVRATERGQAMGLLNAMMSLGWVVGPLLGGYLSAISFELNFMSTLVPLG
VAFLFALRLPE

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the major facilitator superfamily [H]

Homologues:

Organism=Escherichia coli, GI1787291, Length=375, Percent_Identity=24, Blast_Score=70, Evalue=3e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020846
- InterPro:   IPR011701
- InterPro:   IPR016196 [H]

Pfam domain/function: PF07690 MFS_1 [H]

EC number: NA

Molecular weight: Translated: 45033; Mature: 44902

Theoretical pI: Translated: 10.82; Mature: 10.82

Prosite motif: PS50850 MFS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.9 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.6 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSRRELVVTQGRREKAGKIRRIRIKRRNVVLLAVSMFIANAAFGMAFPYLSVYMKLLGGG
CCCCCEEEECCCHHHCCCHHEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCH
MLMVGLLSVAFNLTSTVFQYPFGYLSDRTRNRKAFISFGLFSTGTFYALMAVVSTPLALL
HHHHHHHHHHHHHHHHHHHCCCHHHCCCCCCCEEEEEECCHHHHHHHHHHHHHHCHHHHH
TLRTFQGALGSAIMPAHSALIAELSTRVGSAYGLFGSIENAGYMLGNFIGGFLIKYVGIR
HHHHHHHHHCCHHHHHHHHHHHHHHHHHCHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHH
GIFLIAGALLVLSSAIVLLLRERPRPKRAPRKLILVQEGRESERATFQGAAFKRLMRGHL
HHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHH
GLFYFTVLLVMIASGQVYSVVSVYFEEVFGSEWVGILFGIDSLAAAVSGYYLGKLIDRYG
HHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHC
AKKFYLLAIAGYAIAFLGYAFAKNLYLMIVVALFSGVKWSLTLNASSTYVATKVRATERG
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCCEEEEEEHHHHCH
QAMGLLNAMMSLGWVVGPLLGGYLSAISFELNFMSTLVPLGVAFLFALRLPE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure 
SRRELVVTQGRREKAGKIRRIRIKRRNVVLLAVSMFIANAAFGMAFPYLSVYMKLLGGG
CCCCEEEECCCHHHCCCHHEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCH
MLMVGLLSVAFNLTSTVFQYPFGYLSDRTRNRKAFISFGLFSTGTFYALMAVVSTPLALL
HHHHHHHHHHHHHHHHHHHCCCHHHCCCCCCCEEEEEECCHHHHHHHHHHHHHHCHHHHH
TLRTFQGALGSAIMPAHSALIAELSTRVGSAYGLFGSIENAGYMLGNFIGGFLIKYVGIR
HHHHHHHHHCCHHHHHHHHHHHHHHHHHCHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHH
GIFLIAGALLVLSSAIVLLLRERPRPKRAPRKLILVQEGRESERATFQGAAFKRLMRGHL
HHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHH
GLFYFTVLLVMIASGQVYSVVSVYFEEVFGSEWVGILFGIDSLAAAVSGYYLGKLIDRYG
HHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHC
AKKFYLLAIAGYAIAFLGYAFAKNLYLMIVVALFSGVKWSLTLNASSTYVATKVRATERG
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCCEEEEEEHHHHCH
QAMGLLNAMMSLGWVVGPLLGGYLSAISFELNFMSTLVPLGVAFLFALRLPE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Proton [Periplasm]; drug [Cytoplasm] [C]

Specific reaction: Proton [Periplasm] + drug [Cytoplasm] = Proton [Cytoplasm] + drug [Periplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]