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The map label for this gene is argK [C]

Identifier: 212224224

GI number: 212224224

Start: 992257

End: 993216

Strand: Reverse

Name: argK [C]

Synonym: TON_1075

Alternate gene names: 212224224

Gene position: 993216-992257 (Counterclockwise)

Preceding gene: 212224225

Following gene: 212224223

Centisome position: 53.76

GC content: 52.5

Gene sequence:

>960_bases
ATGATAGACGACCTGATCGAACGCATGCTCCAGGGAGATAAGCGCGCCACGGCCAGGCTGATAACCCTAGTAGAGAACGA
CGAGGATAAAGCTAGAGAAGTAATCAAAAAGATCTACCCCCACACGGGCAATGCCTATATCGTCGGTATCACTGGCCCCC
CTGGAGCTGGAAAATCAACTCTTCTCGACAAGCTGATCAGGGTCGCGAGGGAGGAAGGCAAAGTTGTCGGCGTCATAGCC
ATCGATCCGACCTCGCCTTTCACCGGCGGCGCTCTGCTCGGCGACAGGATAAGGATGCAAAGGCACTCGACTGATCCCGG
CGTTTTTATCAGAAGCATGGCCACACGCGGCTCCCTTGGTGGACTGGCCAAGGCCACAAGTGACGCGATAAAGGTGCTTG
ATGCTTACGGTTGTGACGTTATTTTCGTTGAGACGGTTGGTGTGGGCCAAATAGAGATTGACATCGTCAAAACTGCAGAC
ACAGTCGTCCTTGTTACAGTTCCAGGACTGGGCGACGACATACAGGCTATTAAGGCCGGCCTTATGGAGATAGCGGACAT
TTTCGTCATAAATAAGGCCGACAAAGAAGGGGCAGATGCCACTTACTTCGAACTTAATATGATGCTCGACCTCGAGAAGG
AGCGCTGGGAGAAGCGCGGCTGGAGGCCGCCGATAGTCGAGACCGTGGCGACGACAATGAGAGGCATAAGAGACCTCTGG
AAGGCAATACAAGATCACCATGAGTTCCTTGAAAGGAGTGGCGAAATAGAGCGCAAGAGGAAGTTCCGTGCAGAAGAAGA
GGTTAAGACTATAATCTCCGGTAGAATCGCGAAGATGATAAGTGAGCGCCTCGACGAGGAAGAGGTTTCGGGCCTGATAG
ATAGAATTGTGAAGCGGGAGATAGACCCGTACTCTGCCGCGGATTTGGTTCTTGAAAAAACTCTGGGGGTGAGGGTATGA

Upstream 100 bases:

>100_bases
ACTATTGATTTCATTGATAGGGCCGTAGAGAACCTCAAGCGCTTTAGGGAAGGCTTAACTTTATAATTTCTTTCTTGGAT
AATTTGTCCGAGTGATGACG

Downstream 100 bases:

>100_bases
TAAAGAAAATTGACCACGTCGGTATTGCAGTGAAGAACCTTGAAGAGGCCATAAAGATCTGGGAAGGTCTCGGCCTCAAG
GTCGAGGAGATTGAAGAAGT

Product: lysine/arginine/ornithine transport system kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 319; Mature: 319

Protein sequence:

>319_residues
MIDDLIERMLQGDKRATARLITLVENDEDKAREVIKKIYPHTGNAYIVGITGPPGAGKSTLLDKLIRVAREEGKVVGVIA
IDPTSPFTGGALLGDRIRMQRHSTDPGVFIRSMATRGSLGGLAKATSDAIKVLDAYGCDVIFVETVGVGQIEIDIVKTAD
TVVLVTVPGLGDDIQAIKAGLMEIADIFVINKADKEGADATYFELNMMLDLEKERWEKRGWRPPIVETVATTMRGIRDLW
KAIQDHHEFLERSGEIERKRKFRAEEEVKTIISGRIAKMISERLDEEEVSGLIDRIVKREIDPYSAADLVLEKTLGVRV

Sequences:

>Translated_319_residues
MIDDLIERMLQGDKRATARLITLVENDEDKAREVIKKIYPHTGNAYIVGITGPPGAGKSTLLDKLIRVAREEGKVVGVIA
IDPTSPFTGGALLGDRIRMQRHSTDPGVFIRSMATRGSLGGLAKATSDAIKVLDAYGCDVIFVETVGVGQIEIDIVKTAD
TVVLVTVPGLGDDIQAIKAGLMEIADIFVINKADKEGADATYFELNMMLDLEKERWEKRGWRPPIVETVATTMRGIRDLW
KAIQDHHEFLERSGEIERKRKFRAEEEVKTIISGRIAKMISERLDEEEVSGLIDRIVKREIDPYSAADLVLEKTLGVRV
>Mature_319_residues
MIDDLIERMLQGDKRATARLITLVENDEDKAREVIKKIYPHTGNAYIVGITGPPGAGKSTLLDKLIRVAREEGKVVGVIA
IDPTSPFTGGALLGDRIRMQRHSTDPGVFIRSMATRGSLGGLAKATSDAIKVLDAYGCDVIFVETVGVGQIEIDIVKTAD
TVVLVTVPGLGDDIQAIKAGLMEIADIFVINKADKEGADATYFELNMMLDLEKERWEKRGWRPPIVETVATTMRGIRDLW
KAIQDHHEFLERSGEIERKRKFRAEEEVKTIISGRIAKMISERLDEEEVSGLIDRIVKREIDPYSAADLVLEKTLGVRV

Specific function: May have GTPase activity. May also bind and hydrolyze ATP. May function as chaperone [H]

COG id: COG1703

COG function: function code E; Putative periplasmic protein kinase ArgK and related GTPases of G3E family

Gene ontology:

Cell location: Inner Membrane-Associated [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ArgK family [H]

Homologues:

Organism=Homo sapiens, GI26892295, Length=328, Percent_Identity=30.7926829268293, Blast_Score=172, Evalue=4e-43,
Organism=Escherichia coli, GI1789285, Length=271, Percent_Identity=36.1623616236162, Blast_Score=179, Evalue=3e-46,
Organism=Caenorhabditis elegans, GI71994271, Length=279, Percent_Identity=32.6164874551971, Blast_Score=153, Evalue=1e-37,
Organism=Caenorhabditis elegans, GI71994275, Length=237, Percent_Identity=34.5991561181435, Blast_Score=146, Evalue=1e-35,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005129
- InterPro:   IPR003593 [H]

Pfam domain/function: PF03308 ArgK [H]

EC number: 2.7.-.- [C]

Molecular weight: Translated: 35321; Mature: 35321

Theoretical pI: Translated: 5.22; Mature: 5.22

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIDDLIERMLQGDKRATARLITLVENDEDKAREVIKKIYPHTGNAYIVGITGPPGAGKST
CHHHHHHHHHCCCHHHHHHEEEEEECCHHHHHHHHHHHCCCCCCEEEEEECCCCCCCHHH
LLDKLIRVAREEGKVVGVIAIDPTSPFTGGALLGDRIRMQRHSTDPGVFIRSMATRGSLG
HHHHHHHHHHHCCCEEEEEEECCCCCCCCCHHHHHHHHHHHCCCCCCHHHHHHHHCCCCC
GLAKATSDAIKVLDAYGCDVIFVETVGVGQIEIDIVKTADTVVLVTVPGLGDDIQAIKAG
CHHHHHHHHHHHHHHCCCCEEEEEECCCCEEEEEEEECCCEEEEEEECCCCCHHHHHHHH
LMEIADIFVINKADKEGADATYFELNMMLDLEKERWEKRGWRPPIVETVATTMRGIRDLW
HHHHHHHHEEECCCCCCCCCEEEEEEEEEECHHHHHHHCCCCCHHHHHHHHHHHHHHHHH
KAIQDHHEFLERSGEIERKRKFRAEEEVKTIISGRIAKMISERLDEEEVSGLIDRIVKRE
HHHHHHHHHHHHCCCHHHHHHCCHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHC
IDPYSAADLVLEKTLGVRV
CCCCHHHHHHHHHHHCCCC
>Mature Secondary Structure
MIDDLIERMLQGDKRATARLITLVENDEDKAREVIKKIYPHTGNAYIVGITGPPGAGKST
CHHHHHHHHHCCCHHHHHHEEEEEECCHHHHHHHHHHHCCCCCCEEEEEECCCCCCCHHH
LLDKLIRVAREEGKVVGVIAIDPTSPFTGGALLGDRIRMQRHSTDPGVFIRSMATRGSLG
HHHHHHHHHHHCCCEEEEEEECCCCCCCCCHHHHHHHHHHHCCCCCCHHHHHHHHCCCCC
GLAKATSDAIKVLDAYGCDVIFVETVGVGQIEIDIVKTADTVVLVTVPGLGDDIQAIKAG
CHHHHHHHHHHHHHHCCCCEEEEEECCCCEEEEEEEECCCEEEEEEECCCCCHHHHHHHH
LMEIADIFVINKADKEGADATYFELNMMLDLEKERWEKRGWRPPIVETVATTMRGIRDLW
HHHHHHHHEEECCCCCCCCCEEEEEEEEEECHHHHHHHCCCCCHHHHHHHHHHHHHHHHH
KAIQDHHEFLERSGEIERKRKFRAEEEVKTIISGRIAKMISERLDEEEVSGLIDRIVKRE
HHHHHHHHHHHHCCCHHHHHHCCHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHC
IDPYSAADLVLEKTLGVRV
CCCCHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Arg [C]

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 12622808 [H]