Click here to switch to the map view.

The map label for this gene is lrp [C]

Identifier: 212224129

GI number: 212224129

Start: 903834

End: 904295

Strand: Reverse

Name: lrp [C]

Synonym: TON_0980

Alternate gene names: 212224129

Gene position: 904295-903834 (Counterclockwise)

Preceding gene: 212224130

Following gene: 212224128

Centisome position: 48.94

GC content: 47.84

Gene sequence:

>462_bases
ATGCCGGGGATAGACGAAAAGGATAAAGAAATTCTCAGAATCCTGAGGAAGGAGGGTAGGATAACCCTCACAGAGCTCGG
AAGAAGGGTTAAACTATCCCCGGCGAGCGTGAAGAACCGGGTGGAGAAATTGGAAAAGCTCGGCGCGATTAAGGGTTATT
CTGCCATAATTGACCCTGCTTTCCTCGATGAGTTCGTTCAGGTCCTTTTTGAACTCAAACTTTCAATAGACGACAAGAAC
GTTGATGTGATCCTCAGGAGAATAGCAAAGCTTGAGAACGTCCAAGCCCTATACCGTAGGAGTGGCGAGAAGCAGATACT
CATAAGGGCGAGCTTTCACAATACTGATGAGGTTAAGGAGTTCGCCGGAATGCTGAAAAAGCACTTTGGGAAGAACCTTG
AACGGGTGGAGGTAACACTCATAATCGACACCTTCAAGGAGTGCTGGGTGGCCAATGAGTAG

Upstream 100 bases:

>100_bases
AAGCCGGTCAGAGACTACTTCGAGAAGCATCCAGAGCCTCTCGAACTCATGAGGGAGATAAAGATTACCCGCTGACTCCC
TTTTTCTTTTGGTGAGTGAC

Downstream 100 bases:

>100_bases
GTAAGACGCTGAGGCGTGATGAGTGGACGGCTGGCCGGGGGATAGCTATGCTCTTTGTCATCAGACCAGGAAGAAAGAAG
AACGAGCTCGAAGCTTTTTT

Product: transcription regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 153; Mature: 152

Protein sequence:

>153_residues
MPGIDEKDKEILRILRKEGRITLTELGRRVKLSPASVKNRVEKLEKLGAIKGYSAIIDPAFLDEFVQVLFELKLSIDDKN
VDVILRRIAKLENVQALYRRSGEKQILIRASFHNTDEVKEFAGMLKKHFGKNLERVEVTLIIDTFKECWVANE

Sequences:

>Translated_153_residues
MPGIDEKDKEILRILRKEGRITLTELGRRVKLSPASVKNRVEKLEKLGAIKGYSAIIDPAFLDEFVQVLFELKLSIDDKN
VDVILRRIAKLENVQALYRRSGEKQILIRASFHNTDEVKEFAGMLKKHFGKNLERVEVTLIIDTFKECWVANE
>Mature_152_residues
PGIDEKDKEILRILRKEGRITLTELGRRVKLSPASVKNRVEKLEKLGAIKGYSAIIDPAFLDEFVQVLFELKLSIDDKNV
DVILRRIAKLENVQALYRRSGEKQILIRASFHNTDEVKEFAGMLKKHFGKNLERVEVTLIIDTFKECWVANE

Specific function: Mediates A Global Response To Leucine. Exogenous Leucine Affects The Expression Of A Number Of Different Operons; Lrp Mediates This Effect For At Least Some Of These Operons. For Example It Is Regulator Of The Branched-Chain Amino Acid Transport Genes. [

COG id: COG1522

COG function: function code K; Transcriptional regulators

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH asnC-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1787116, Length=125, Percent_Identity=33.6, Blast_Score=70, Evalue=9e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011008
- InterPro:   IPR000485
- InterPro:   IPR019885
- InterPro:   IPR000835
- InterPro:   IPR019888
- InterPro:   IPR019887
- InterPro:   IPR011991 [H]

Pfam domain/function: PF01037 AsnC_trans_reg; PF01047 MarR [H]

EC number: NA

Molecular weight: Translated: 17651; Mature: 17520

Theoretical pI: Translated: 9.77; Mature: 9.77

Prosite motif: PS50956 HTH_ASNC_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
0.7 %Met     (Mature Protein)
1.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPGIDEKDKEILRILRKEGRITLTELGRRVKLSPASVKNRVEKLEKLGAIKGYSAIIDPA
CCCCCHHHHHHHHHHHHCCCEEHHHCCCEECCCHHHHHHHHHHHHHHCCCCCHHHHCCHH
FLDEFVQVLFELKLSIDDKNVDVILRRIAKLENVQALYRRSGEKQILIRASFHNTDEVKE
HHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCHHHHHH
FAGMLKKHFGKNLERVEVTLIIDTFKECWVANE
HHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure 
PGIDEKDKEILRILRKEGRITLTELGRRVKLSPASVKNRVEKLEKLGAIKGYSAIIDPA
CCCCHHHHHHHHHHHHCCCEEHHHCCCEECCCHHHHHHHHHHHHHHCCCCCHHHHCCHH
FLDEFVQVLFELKLSIDDKNVDVILRRIAKLENVQALYRRSGEKQILIRASFHNTDEVKE
HHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCHHHHHH
FAGMLKKHFGKNLERVEVTLIIDTFKECWVANE
HHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA