Click here to switch to the map view.

The map label for this gene is pfdA

Identifier: 212224063

GI number: 212224063

Start: 844895

End: 845338

Strand: Reverse

Name: pfdA

Synonym: TON_0914

Alternate gene names: 212224063

Gene position: 845338-844895 (Counterclockwise)

Preceding gene: 212224064

Following gene: 212224062

Centisome position: 45.75

GC content: 52.7

Gene sequence:

>444_bases
ATGGCGGAGAGAAACGAGCAGCTTGAAAGGCTCGCTTACGAGTATCAGCTCCTGCAGGCTCAGGCTCAGCTTTTAGCCCA
GAATCTTGAGCTCCTAACCCTCGGAAGGAACGAGTTCCAGGCCGTTAAGCAGACCCTCGAGGAGCTCAAAAAGGTCGAGG
ATGAGAAGCCGGAAATTCTGGTGCCAATCGGTGCAGGCTCCTTCCTGAAAGGTATGATAGTGGATAAGAACAGCGCGATA
GTCAGCGTCGGTTCTGGCTATGCTACCGAGAAGAGCCTCGACGACGCTATAGGCTACCTTGATGCTAGAATAAAAGAGTA
CGACGAGGCAATAAGGAAAACGCAGGAGGCTCTGGCAAAGCTTGAGGGTCAGCTCCAGGAGCTCGCTCAGAAAGCACAGA
AGCTCCAGCAGGAGGCTGCGATGCGTTTTAGTGTAAAGGAGTAA

Upstream 100 bases:

>100_bases
TTAGAGCTCGTGCGTGGCTGGTTCTATAACCTTTCGTGGTTTGTGGCGAGGCAACCCAAACCTTAAAAGCCTCCCATCCA
AATCCAATCGGTGGTGCAAA

Downstream 100 bases:

>100_bases
TGTTTTTGAGCTTCTTCTCCTCCACTTTATGGGTTTGAAAAGCAAAATTGGGAGATAATATTTTAAACTTTCTCCGCTAC
AATGCATTTTAAGATGGGAA

Product: prefoldin subunit alpha

Products: NA

Alternate protein names: GimC subunit alpha

Number of amino acids: Translated: 147; Mature: 146

Protein sequence:

>147_residues
MAERNEQLERLAYEYQLLQAQAQLLAQNLELLTLGRNEFQAVKQTLEELKKVEDEKPEILVPIGAGSFLKGMIVDKNSAI
VSVGSGYATEKSLDDAIGYLDARIKEYDEAIRKTQEALAKLEGQLQELAQKAQKLQQEAAMRFSVKE

Sequences:

>Translated_147_residues
MAERNEQLERLAYEYQLLQAQAQLLAQNLELLTLGRNEFQAVKQTLEELKKVEDEKPEILVPIGAGSFLKGMIVDKNSAI
VSVGSGYATEKSLDDAIGYLDARIKEYDEAIRKTQEALAKLEGQLQELAQKAQKLQQEAAMRFSVKE
>Mature_146_residues
AERNEQLERLAYEYQLLQAQAQLLAQNLELLTLGRNEFQAVKQTLEELKKVEDEKPEILVPIGAGSFLKGMIVDKNSAIV
SVGSGYATEKSLDDAIGYLDARIKEYDEAIRKTQEALAKLEGQLQELAQKAQKLQQEAAMRFSVKE

Specific function: Molecular chaperone capable of stabilizing a range of proteins. Seems to fulfill an ATP-independent, HSP70-like function in archaeal de novo protein folding

COG id: COG1730

COG function: function code O; Predicted prefoldin, molecular chaperone implicated in de novo protein folding

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the prefoldin alpha subunit family

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): PFDA_THEON (B6YWD9)

Other databases:

- EMBL:   CP000855
- RefSeq:   YP_002307299.1
- GeneID:   7017217
- GenomeReviews:   CP000855_GR
- KEGG:   ton:TON_0914
- HOGENOM:   HBG727147
- OMA:   YEYQLLQ
- ProtClustDB:   PRK03947
- HAMAP:   MF_00308
- InterPro:   IPR011599
- InterPro:   IPR009053
- InterPro:   IPR004127
- TIGRFAMs:   TIGR00293

Pfam domain/function: PF02996 Prefoldin; SSF46579 Prefoldin

EC number: NA

Molecular weight: Translated: 16514; Mature: 16383

Theoretical pI: Translated: 4.57; Mature: 4.57

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
1.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAERNEQLERLAYEYQLLQAQAQLLAQNLELLTLGRNEFQAVKQTLEELKKVEDEKPEIL
CCCHHHHHHHHHHHHHHHHHHHHHHHHCCHHHCCCCHHHHHHHHHHHHHHHHCCCCCCEE
VPIGAGSFLKGMIVDKNSAIVSVGSGYATEKSLDDAIGYLDARIKEYDEAIRKTQEALAK
EEECCCHHHHHHEECCCCCEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LEGQLQELAQKAQKLQQEAAMRFSVKE
HHHHHHHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure 
AERNEQLERLAYEYQLLQAQAQLLAQNLELLTLGRNEFQAVKQTLEELKKVEDEKPEIL
CCHHHHHHHHHHHHHHHHHHHHHHHHCCHHHCCCCHHHHHHHHHHHHHHHHCCCCCCEE
VPIGAGSFLKGMIVDKNSAIVSVGSGYATEKSLDDAIGYLDARIKEYDEAIRKTQEALAK
EEECCCHHHHHHEECCCCCEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LEGQLQELAQKAQKLQQEAAMRFSVKE
HHHHHHHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA