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The map label for this gene is aspC [H]

Identifier: 212223713

GI number: 212223713

Start: 518042

End: 519211

Strand: Reverse

Name: aspC [H]

Synonym: TON_0565

Alternate gene names: 212223713

Gene position: 519211-518042 (Counterclockwise)

Preceding gene: 212223714

Following gene: 212223709

Centisome position: 28.1

GC content: 52.14

Gene sequence:

>1170_bases
ATGGCGCTGAGCGACAGGTTAGAACTCGTTAACCCTTCTGAGATCAGAAAGCTTTTTGACCTAGCTCAGGGCGTTGAGGG
TCTCATCTCACTTGGAATCGGAGAGCCGGACTTCGATACTCCAGAGCATATAAAAGAGTATGCCAAAGAGGCTCTCGACA
AAGGAATGACGCATTATAGCCCCAACGCTGGAATCATGATGCTCCGTGAGGCCGTTGCGTGGAAGCTGAAGGAACAGAAC
GGCATTGAAGTTGACCCAAAGAGCCAGGTAATGATAACCGTCGGAGCCAATCAGGCGTTCGTCATGGGGCTCGCGGCGTT
TCTCAAGGATAGAGAGGAGGTCTTAATTCCAAGCCCAATGTTTGTGAGTTATGCCCCCGCAGTAATCCTCGCGGGAGGGA
AGCCTGTCGAAGTTCCAACATATGAAGAAAACGAGTTCCGTCTGAGTGTTGACGACCTGAAGAAGCACGTATCTGAGAAG
ACGCGTGCGCTCATCATAAACAGCCCAAACAACCCCACTGGAGCGGTTCTCACCAAGAAGGACGTGGAGGAAATCGCTGA
CTTCGCGGTGGAGCACGACCTTATCATCTTCAGCGACGAGGTTTACGAGCACTTCGTTTATGATGGTGTCAAAAACTACA
GCATAGCGGCTCTCGACGGCATGTTCGAGAGAACAATAACGATAAACGGCTTCTCCAAGACCTTTGCCATGACAGGCTGG
CGTCTTGGCTTCGTGGCCGCACCGGAGTGGATAATTGAAAAGATGACCCGCTTCCAGATGTACAACGCCACCTGCCCAGT
GACCTTCGCCCAGTACGCCGCTGCAAAGGCTTTGAAAGACGAGAGGAGTTGGAAAGCCGTTGAGGAGATGAAAAAGGAGT
ACGAGAGGAGAAGAAACCTCGTCTGGAAGCGTCTCAACGAGATGGGCCTGCCGACGGTCAAACCGAAAGGAGCATTCTAC
ATATTCCCGCGCATAAGGGACACCGGACTCACGAGCAGGGAGTTCAGCGAGATGATGCTCCTCGAGGCCAAAGTCGCCAT
TGTTCCTGGAAGTGCCTTTGGAGAGGCTGGCGAGGGCTACATAAGGATAAGCTACGCGACTGCATACGAACAGCTTGAGG
AAGCTATGGATAGGATGGAGAAGGTTTTGAGGGAGAAGAAGCTCGTTTAG

Upstream 100 bases:

>100_bases
GGATTTGTCGTCCATCAATGAAATTTACTATTCTTTGATGTCCATCTTTTTGCCAAGGTAAAGTTATAAACATTGGGCCG
AAGAACTTTCGGTGATGTTC

Downstream 100 bases:

>100_bases
AGCTTTCTTAACTCTATCTTTACTTCCTTTTCTGGCTTGAAGTCTATAACCGCATAGTAACCCCTGAAGAGTGGTCCAGG
GTTCACGATGTGGGTTTCTC

Product: aspartate aminotransferase

Products: NA

Alternate protein names: AspAT; Transaminase A [H]

Number of amino acids: Translated: 389; Mature: 388

Protein sequence:

>389_residues
MALSDRLELVNPSEIRKLFDLAQGVEGLISLGIGEPDFDTPEHIKEYAKEALDKGMTHYSPNAGIMMLREAVAWKLKEQN
GIEVDPKSQVMITVGANQAFVMGLAAFLKDREEVLIPSPMFVSYAPAVILAGGKPVEVPTYEENEFRLSVDDLKKHVSEK
TRALIINSPNNPTGAVLTKKDVEEIADFAVEHDLIIFSDEVYEHFVYDGVKNYSIAALDGMFERTITINGFSKTFAMTGW
RLGFVAAPEWIIEKMTRFQMYNATCPVTFAQYAAAKALKDERSWKAVEEMKKEYERRRNLVWKRLNEMGLPTVKPKGAFY
IFPRIRDTGLTSREFSEMMLLEAKVAIVPGSAFGEAGEGYIRISYATAYEQLEEAMDRMEKVLREKKLV

Sequences:

>Translated_389_residues
MALSDRLELVNPSEIRKLFDLAQGVEGLISLGIGEPDFDTPEHIKEYAKEALDKGMTHYSPNAGIMMLREAVAWKLKEQN
GIEVDPKSQVMITVGANQAFVMGLAAFLKDREEVLIPSPMFVSYAPAVILAGGKPVEVPTYEENEFRLSVDDLKKHVSEK
TRALIINSPNNPTGAVLTKKDVEEIADFAVEHDLIIFSDEVYEHFVYDGVKNYSIAALDGMFERTITINGFSKTFAMTGW
RLGFVAAPEWIIEKMTRFQMYNATCPVTFAQYAAAKALKDERSWKAVEEMKKEYERRRNLVWKRLNEMGLPTVKPKGAFY
IFPRIRDTGLTSREFSEMMLLEAKVAIVPGSAFGEAGEGYIRISYATAYEQLEEAMDRMEKVLREKKLV
>Mature_388_residues
ALSDRLELVNPSEIRKLFDLAQGVEGLISLGIGEPDFDTPEHIKEYAKEALDKGMTHYSPNAGIMMLREAVAWKLKEQNG
IEVDPKSQVMITVGANQAFVMGLAAFLKDREEVLIPSPMFVSYAPAVILAGGKPVEVPTYEENEFRLSVDDLKKHVSEKT
RALIINSPNNPTGAVLTKKDVEEIADFAVEHDLIIFSDEVYEHFVYDGVKNYSIAALDGMFERTITINGFSKTFAMTGWR
LGFVAAPEWIIEKMTRFQMYNATCPVTFAQYAAAKALKDERSWKAVEEMKKEYERRRNLVWKRLNEMGLPTVKPKGAFYI
FPRIRDTGLTSREFSEMMLLEAKVAIVPGSAFGEAGEGYIRISYATAYEQLEEAMDRMEKVLREKKLV

Specific function: Unknown

COG id: COG0436

COG function: function code E; Aspartate/tyrosine/aromatic aminotransferase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family [H]

Homologues:

Organism=Homo sapiens, GI95147551, Length=396, Percent_Identity=29.5454545454545, Blast_Score=174, Evalue=9e-44,
Organism=Homo sapiens, GI169881279, Length=396, Percent_Identity=29.5454545454545, Blast_Score=174, Evalue=9e-44,
Organism=Homo sapiens, GI56713254, Length=387, Percent_Identity=28.4237726098191, Blast_Score=171, Evalue=1e-42,
Organism=Homo sapiens, GI56713256, Length=396, Percent_Identity=27.7777777777778, Blast_Score=171, Evalue=1e-42,
Organism=Homo sapiens, GI169881281, Length=308, Percent_Identity=29.5454545454545, Blast_Score=139, Evalue=5e-33,
Organism=Homo sapiens, GI4507369, Length=383, Percent_Identity=25.065274151436, Blast_Score=108, Evalue=8e-24,
Organism=Homo sapiens, GI4885351, Length=379, Percent_Identity=25.5936675461741, Blast_Score=94, Evalue=3e-19,
Organism=Homo sapiens, GI187936925, Length=405, Percent_Identity=25.9259259259259, Blast_Score=93, Evalue=4e-19,
Organism=Homo sapiens, GI14211921, Length=405, Percent_Identity=25.9259259259259, Blast_Score=93, Evalue=4e-19,
Organism=Homo sapiens, GI19263340, Length=395, Percent_Identity=24.8101265822785, Blast_Score=89, Evalue=7e-18,
Organism=Homo sapiens, GI215599424, Length=398, Percent_Identity=24.6231155778894, Blast_Score=89, Evalue=7e-18,
Organism=Homo sapiens, GI7705897, Length=415, Percent_Identity=24.3373493975904, Blast_Score=86, Evalue=4e-17,
Organism=Homo sapiens, GI33469970, Length=415, Percent_Identity=24.3373493975904, Blast_Score=86, Evalue=4e-17,
Organism=Homo sapiens, GI149944424, Length=392, Percent_Identity=23.9795918367347, Blast_Score=74, Evalue=3e-13,
Organism=Escherichia coli, GI1788722, Length=367, Percent_Identity=27.7929155313352, Blast_Score=177, Evalue=8e-46,
Organism=Escherichia coli, GI1786816, Length=366, Percent_Identity=29.7814207650273, Blast_Score=176, Evalue=3e-45,
Organism=Escherichia coli, GI1788627, Length=372, Percent_Identity=29.3010752688172, Blast_Score=155, Evalue=4e-39,
Organism=Escherichia coli, GI1790797, Length=382, Percent_Identity=25.6544502617801, Blast_Score=86, Evalue=3e-18,
Organism=Escherichia coli, GI48994949, Length=362, Percent_Identity=23.4806629834254, Blast_Score=74, Evalue=2e-14,
Organism=Escherichia coli, GI1787710, Length=328, Percent_Identity=22.5609756097561, Blast_Score=66, Evalue=3e-12,
Organism=Caenorhabditis elegans, GI71994472, Length=388, Percent_Identity=28.6082474226804, Blast_Score=165, Evalue=5e-41,
Organism=Caenorhabditis elegans, GI71994476, Length=388, Percent_Identity=28.6082474226804, Blast_Score=164, Evalue=5e-41,
Organism=Caenorhabditis elegans, GI17567369, Length=358, Percent_Identity=28.4916201117318, Blast_Score=149, Evalue=3e-36,
Organism=Caenorhabditis elegans, GI17567663, Length=392, Percent_Identity=28.0612244897959, Blast_Score=133, Evalue=1e-31,
Organism=Caenorhabditis elegans, GI71981209, Length=397, Percent_Identity=24.9370277078086, Blast_Score=74, Evalue=1e-13,
Organism=Caenorhabditis elegans, GI71981215, Length=178, Percent_Identity=26.9662921348315, Blast_Score=65, Evalue=5e-11,
Organism=Saccharomyces cerevisiae, GI6322401, Length=401, Percent_Identity=27.930174563591, Blast_Score=142, Evalue=8e-35,
Organism=Saccharomyces cerevisiae, GI6320317, Length=349, Percent_Identity=26.647564469914, Blast_Score=102, Evalue=1e-22,
Organism=Saccharomyces cerevisiae, GI6323118, Length=352, Percent_Identity=25, Blast_Score=93, Evalue=6e-20,
Organism=Drosophila melanogaster, GI28573069, Length=413, Percent_Identity=28.3292978208232, Blast_Score=155, Evalue=5e-38,
Organism=Drosophila melanogaster, GI24646114, Length=413, Percent_Identity=28.3292978208232, Blast_Score=155, Evalue=5e-38,
Organism=Drosophila melanogaster, GI28573067, Length=413, Percent_Identity=28.3292978208232, Blast_Score=155, Evalue=5e-38,
Organism=Drosophila melanogaster, GI28573065, Length=413, Percent_Identity=28.3292978208232, Blast_Score=155, Evalue=5e-38,
Organism=Drosophila melanogaster, GI18859735, Length=380, Percent_Identity=27.1052631578947, Blast_Score=119, Evalue=3e-27,
Organism=Drosophila melanogaster, GI24641770, Length=384, Percent_Identity=25.2604166666667, Blast_Score=95, Evalue=8e-20,
Organism=Drosophila melanogaster, GI24641760, Length=384, Percent_Identity=25.2604166666667, Blast_Score=95, Evalue=8e-20,
Organism=Drosophila melanogaster, GI24641768, Length=384, Percent_Identity=25.2604166666667, Blast_Score=95, Evalue=8e-20,
Organism=Drosophila melanogaster, GI24641766, Length=384, Percent_Identity=25.2604166666667, Blast_Score=95, Evalue=8e-20,
Organism=Drosophila melanogaster, GI24641764, Length=384, Percent_Identity=25.2604166666667, Blast_Score=95, Evalue=8e-20,
Organism=Drosophila melanogaster, GI45551451, Length=384, Percent_Identity=25.2604166666667, Blast_Score=95, Evalue=9e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001176
- InterPro:   IPR004839
- InterPro:   IPR004838
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00155 Aminotran_1_2 [H]

EC number: =2.6.1.1 [H]

Molecular weight: Translated: 43940; Mature: 43809

Theoretical pI: Translated: 5.07; Mature: 5.07

Prosite motif: PS00105 AA_TRANSFER_CLASS_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
4.4 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
4.1 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MALSDRLELVNPSEIRKLFDLAQGVEGLISLGIGEPDFDTPEHIKEYAKEALDKGMTHYS
CCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHCCCCCCC
PNAGIMMLREAVAWKLKEQNGIEVDPKSQVMITVGANQAFVMGLAAFLKDREEVLIPSPM
CCCCHHHHHHHHHHHHHCCCCCEECCCCCEEEEECCCHHHHHHHHHHHCCCCCEECCCCH
FVSYAPAVILAGGKPVEVPTYEENEFRLSVDDLKKHVSEKTRALIINSPNNPTGAVLTKK
HHHCCCEEEEECCCCCCCCCCCCCCEEEEHHHHHHHHHHCCEEEEEECCCCCCCCEEEHH
DVEEIADFAVEHDLIIFSDEVYEHFVYDGVKNYSIAALDGMFERTITINGFSKTFAMTGW
HHHHHHHHHHHCCEEEEEHHHHHHHHHCCCCCCEEEEHHCCEEEEEEECCCHHHHHHCCC
RLGFVAAPEWIIEKMTRFQMYNATCPVTFAQYAAAKALKDERSWKAVEEMKKEYERRRNL
EEEEEECCHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VWKRLNEMGLPTVKPKGAFYIFPRIRDTGLTSREFSEMMLLEAKVAIVPGSAFGEAGEGY
HHHHHHHCCCCCCCCCCCEEEEECCCCCCCCHHHHHHHHHHHEEEEEECCCCCCCCCCCE
IRISYATAYEQLEEAMDRMEKVLREKKLV
EEEEHHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
ALSDRLELVNPSEIRKLFDLAQGVEGLISLGIGEPDFDTPEHIKEYAKEALDKGMTHYS
CCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHCCCCCCC
PNAGIMMLREAVAWKLKEQNGIEVDPKSQVMITVGANQAFVMGLAAFLKDREEVLIPSPM
CCCCHHHHHHHHHHHHHCCCCCEECCCCCEEEEECCCHHHHHHHHHHHCCCCCEECCCCH
FVSYAPAVILAGGKPVEVPTYEENEFRLSVDDLKKHVSEKTRALIINSPNNPTGAVLTKK
HHHCCCEEEEECCCCCCCCCCCCCCEEEEHHHHHHHHHHCCEEEEEECCCCCCCCEEEHH
DVEEIADFAVEHDLIIFSDEVYEHFVYDGVKNYSIAALDGMFERTITINGFSKTFAMTGW
HHHHHHHHHHHCCEEEEEHHHHHHHHHCCCCCCEEEEHHCCEEEEEEECCCHHHHHHCCC
RLGFVAAPEWIIEKMTRFQMYNATCPVTFAQYAAAKALKDERSWKAVEEMKKEYERRRNL
EEEEEECCHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VWKRLNEMGLPTVKPKGAFYIFPRIRDTGLTSREFSEMMLLEAKVAIVPGSAFGEAGEGY
HHHHHHHCCCCCCCCCCCEEEEECCCCCCCCHHHHHHHHHHHEEEEEECCCCCCCCCCCE
IRISYATAYEQLEEAMDRMEKVLREKKLV
EEEEHHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12622808 [H]