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The map label for this gene is 212223452

Identifier: 212223452

GI number: 212223452

Start: 272081

End: 273247

Strand: Reverse

Name: 212223452

Synonym: TON_0306

Alternate gene names: NA

Gene position: 273247-272081 (Counterclockwise)

Preceding gene: 212223453

Following gene: 212223451

Centisome position: 14.79

GC content: 52.1

Gene sequence:

>1167_bases
ATGAGTGAGAGGTTCTGCTACAGGTGTGGAATAAGCGAGAGCGAGGGTGGGCCTCTAGTGGTTGGTCTCTGCCAGGTGTG
CTTCCGTAAAGAGAACCCTGTCCTGCTCATCGAAAGAGAGATAAACACAGAGCTCTGTCAAAACTGTGGGAGCTACAAGA
AGCGAGGGGTGTGGGTTGACCCGAGCACCTACGAGCTTGAGGAGCTTATTTTTGAAGTTGCTGAGGGTGCTCTCCTTGAG
GAGCTCGGGGATTCCCTCGATGAACGCGTGAGGAGCTTTGAAGTAGTTTCAATGGAAGAACTTGGAGAAATAAACGATCT
CCCGGTTGGAGCGGCAGTAGTAGCCTTCCAGCCGGTGGACTGGCACATCGAGTACTTCCCTGCCATAATAACCTATGAAG
TTCGTGTTAAAGCCAGAATCCACGAGCTCCAGCGCGAGCTCCACGATGAGGTCAAGTACGTGACGGTCTACGTCCGCCAG
ACGGTATGTCCCCGCTGTCAGAAGTTCCTCGGCGGTTACTTTGAGGCTATCCTTCAGGTCAGGGCGGAAGATAGGCCATT
AACAGAGGCGGAAAGGAAGGCCATAGGCAAGCTCGTGGAGGAGAAGGTTGACGAGATAATGCGCAAGGACAGGATGGGCT
TCATTCAAGATACTATAGAGAAGGAGGAAGGCTTGGACTTCTACATGGGTTCGACTTCGAGTGCCAGAAAGCTTGCCCAG
GCAATAAAGGAACGCTTCGGCGGAACAATAAGTGAGGCCTATGAACTCGTGGGCATGGACAGGCTGACGAGTAAGGAAGT
CTACCGCACGAGCGTAAGCATTAGAATCCCGAAGTTCCAGAAAGGGGACATAGTTGAAGATAGGCGCGGCAACGTCTATG
AAGTTGAGAGGGTCGATGGGAAGGGCATGAGCCTCAGGAACCTTTCGACCAACGAAAGTGAGCACAGGGACTGGAAGACC
GTGAAGAGGGAGGGTATAGATTGGGTGGAGTACGAGAAAAGCGAGGCAATGGTGACAAGCATAACCCCAAACGAAGTTCA
GCTGATGGATATGGAAACCTATGAGACGTATGAGCTTGACAAGCCAGGCATTGATCTGAGGGAAGGTGAGATATACCGCA
TGGTGGAGGTCAGGGGCAGGAAGTACTTCCTTAGGAAGAAGGAGTGA

Upstream 100 bases:

>100_bases
GGATCCAGGGAATTCCACATGCCCAAATGGCCAAGATGTTCCTCTGAGGAAATCAGAGATTTTTTAAACATCCCTTCTCA
CTTCTTCTCCGGTGAGAACT

Downstream 100 bases:

>100_bases
TCCGCTTTTGTCCGCCAACTTTTTTAACCGTAGGTTTTGAACCTCTTTTGGTGATTCTTATGAAGAAGACAGTCGTTATC
ATAGGTGGTGGAGCAGCTGG

Product: nonsense-mediated mRNA decay protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 388; Mature: 387

Protein sequence:

>388_residues
MSERFCYRCGISESEGGPLVVGLCQVCFRKENPVLLIEREINTELCQNCGSYKKRGVWVDPSTYELEELIFEVAEGALLE
ELGDSLDERVRSFEVVSMEELGEINDLPVGAAVVAFQPVDWHIEYFPAIITYEVRVKARIHELQRELHDEVKYVTVYVRQ
TVCPRCQKFLGGYFEAILQVRAEDRPLTEAERKAIGKLVEEKVDEIMRKDRMGFIQDTIEKEEGLDFYMGSTSSARKLAQ
AIKERFGGTISEAYELVGMDRLTSKEVYRTSVSIRIPKFQKGDIVEDRRGNVYEVERVDGKGMSLRNLSTNESEHRDWKT
VKREGIDWVEYEKSEAMVTSITPNEVQLMDMETYETYELDKPGIDLREGEIYRMVEVRGRKYFLRKKE

Sequences:

>Translated_388_residues
MSERFCYRCGISESEGGPLVVGLCQVCFRKENPVLLIEREINTELCQNCGSYKKRGVWVDPSTYELEELIFEVAEGALLE
ELGDSLDERVRSFEVVSMEELGEINDLPVGAAVVAFQPVDWHIEYFPAIITYEVRVKARIHELQRELHDEVKYVTVYVRQ
TVCPRCQKFLGGYFEAILQVRAEDRPLTEAERKAIGKLVEEKVDEIMRKDRMGFIQDTIEKEEGLDFYMGSTSSARKLAQ
AIKERFGGTISEAYELVGMDRLTSKEVYRTSVSIRIPKFQKGDIVEDRRGNVYEVERVDGKGMSLRNLSTNESEHRDWKT
VKREGIDWVEYEKSEAMVTSITPNEVQLMDMETYETYELDKPGIDLREGEIYRMVEVRGRKYFLRKKE
>Mature_387_residues
SERFCYRCGISESEGGPLVVGLCQVCFRKENPVLLIEREINTELCQNCGSYKKRGVWVDPSTYELEELIFEVAEGALLEE
LGDSLDERVRSFEVVSMEELGEINDLPVGAAVVAFQPVDWHIEYFPAIITYEVRVKARIHELQRELHDEVKYVTVYVRQT
VCPRCQKFLGGYFEAILQVRAEDRPLTEAERKAIGKLVEEKVDEIMRKDRMGFIQDTIEKEEGLDFYMGSTSSARKLAQA
IKERFGGTISEAYELVGMDRLTSKEVYRTSVSIRIPKFQKGDIVEDRRGNVYEVERVDGKGMSLRNLSTNESEHRDWKTV
KREGIDWVEYEKSEAMVTSITPNEVQLMDMETYETYELDKPGIDLREGEIYRMVEVRGRKYFLRKKE

Specific function: Unknown

COG id: COG1499

COG function: function code J; NMD protein affecting ribosome stability and mRNA decay

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR007064 [H]

Pfam domain/function: PF04981 NMD3 [H]

EC number: NA

Molecular weight: Translated: 44982; Mature: 44851

Theoretical pI: Translated: 4.69; Mature: 4.69

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.1 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
4.9 %Cys+Met (Translated Protein)
2.1 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSERFCYRCGISESEGGPLVVGLCQVCFRKENPVLLIEREINTELCQNCGSYKKRGVWVD
CCCCEEEECCCCCCCCCCCHHHHHHHHHCCCCCEEEEEECCCHHHHHCCCCHHHCCEEEC
PSTYELEELIFEVAEGALLEELGDSLDERVRSFEVVSMEELGEINDLPVGAAVVAFQPVD
CCHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHEEEECHHHHCCCCCCCCCEEEEEECCCC
WHIEYFPAIITYEVRVKARIHELQRELHDEVKYVTVYVRQTVCPRCQKFLGGYFEAILQV
CCCEEECEEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RAEDRPLTEAERKAIGKLVEEKVDEIMRKDRMGFIQDTIEKEEGLDFYMGSTSSARKLAQ
HCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCEEEECCCHHHHHHHH
AIKERFGGTISEAYELVGMDRLTSKEVYRTSVSIRIPKFQKGDIVEDRRGNVYEVERVDG
HHHHHHCCCHHHHHHHHCCHHHHHHHHHHEEEEEECCCCCCCCCCCCCCCCEEEEEECCC
KGMSLRNLSTNESEHRDWKTVKREGIDWVEYEKSEAMVTSITPNEVQLMDMETYETYELD
CCCEEECCCCCCCHHHHHHHHHHCCCCCEEECCCCCEEEECCCCCEEEEECCCCCEEECC
KPGIDLREGEIYRMVEVRGRKYFLRKKE
CCCCCCCCCCEEEEEECCCCEEECCCCC
>Mature Secondary Structure 
SERFCYRCGISESEGGPLVVGLCQVCFRKENPVLLIEREINTELCQNCGSYKKRGVWVD
CCCEEEECCCCCCCCCCCHHHHHHHHHCCCCCEEEEEECCCHHHHHCCCCHHHCCEEEC
PSTYELEELIFEVAEGALLEELGDSLDERVRSFEVVSMEELGEINDLPVGAAVVAFQPVD
CCHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHEEEECHHHHCCCCCCCCCEEEEEECCCC
WHIEYFPAIITYEVRVKARIHELQRELHDEVKYVTVYVRQTVCPRCQKFLGGYFEAILQV
CCCEEECEEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RAEDRPLTEAERKAIGKLVEEKVDEIMRKDRMGFIQDTIEKEEGLDFYMGSTSSARKLAQ
HCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCEEEECCCHHHHHHHH
AIKERFGGTISEAYELVGMDRLTSKEVYRTSVSIRIPKFQKGDIVEDRRGNVYEVERVDG
HHHHHHCCCHHHHHHHHCCHHHHHHHHHHEEEEEECCCCCCCCCCCCCCCCEEEEEECCC
KGMSLRNLSTNESEHRDWKTVKREGIDWVEYEKSEAMVTSITPNEVQLMDMETYETYELD
CCCEEECCCCCCCHHHHHHHHHHCCCCCEEECCCCCEEEECCCCCEEEEECCCCCEEECC
KPGIDLREGEIYRMVEVRGRKYFLRKKE
CCCCCCCCCCEEEEEECCCCEEECCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]