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The map label for this gene is ygbD [C]

Identifier: 212223451

GI number: 212223451

Start: 270696

End: 272021

Strand: Reverse

Name: ygbD [C]

Synonym: TON_0305

Alternate gene names: 212223451

Gene position: 272021-270696 (Counterclockwise)

Preceding gene: 212223452

Following gene: 212223446

Centisome position: 14.72

GC content: 53.85

Gene sequence:

>1326_bases
ATGAAGAAGACAGTCGTTATCATAGGTGGTGGAGCAGCTGGAATGAGCGCTGCATCTCGCATCAAGCGCCTGAAGCCGGA
ATGGGACGTTAAGGTCTTTGAAGCAACAGAATGGGTCAGCCACGCTCCCTGCGGAGTTCCATACGTGGTAGAAGGAATCT
CGCCGAAGGAGAAGCTCATGCACTATCCACCGGAGGTTTTCATTAAGAAGCGTGGCATAGACCTTCACATGAAGGCAGAG
GTAATAGAGGTCGAAGAGGGTTCTGTGAGGGTTCGCGAGGAAGACGGGGAACACACCTACGAGTGGGATTACCTCGTCTT
CGCCAACGGTGCTTCTCCTCATGTTCCACCCATAGAGGGACTCGAGCTAGAGGGAGTTTTCACTGCAGATCTCCCTCCGG
ATGCCGTTGCGATAAGAGATTACATTGAGAAGAACAAGGTTGAAAACGTCGTCATCATTGGAACGGGCTACATAGCCATC
GAGATGGCCGAGGCCTTTGTCGCCCAGGGCAAGAACGTAACGCTCATCGGCAGGAGTGAGCGCGTTCTTAGAAAGACCTT
CGACAAGGAGATCACTGACATTGTGGAGGAGAAACTCAAAGCCCACCTCAACCTCCGCCTGCAGGAGCTGACGATGAGGA
TAGAGGGTGACGGAAGGGTCGAAAAGGTAGTCACCGACGCCTCCGAGTATCCCGCTGACCTTGTTATAATCGCGACGGGC
ATAAAACCCAACACTGAACTAGCCAAACAGCTTGGAGTTAGAACAGGCGAAACTGGGGCAATCTGGACGAACGAAAAGAT
GCAGACCAGTGTTGAGAACGTCTATGCCGCTGGAGATGTAGCAGAGACTCGGCATATCATAACCGGCAGGCGCGTGTGGA
TTCCACTGGCTCCGTCAGGCAATAAGATGGGCTACGTGGCCGGGAGCAACATCGCCGGCAAGGAAATAACCTTCCCGGGT
GTCCTTGGTACCAGCATAACCAAGTTCCTTGACCTTGAGATAGGTAAGACCGGTCTCACCGAGGCCGAGGCCATAAAAGA
GGGCTACGACGTTAGAACCGCCTTCATAAAGGCGAAGACAAGACCGCACTACTATCCTGGGGCTAAGGAAATCCATCTCA
AGGGCGTCGTTGACAACGAGACCAACAGGCTGCTTGGCGTTCAGGCCGTCGGTGGGGAGATACTGCCAAGGATTGACGCT
GCAGCGGCCATGATTCAGGCTGGATTCACCACGAAGGATGTTTTCTTCACGGATCTGGCCTACGCGCCACCCTTCGCTCC
CGTGTGGGACCCTCTGATAGTCCTAGCTAGGGTTCTGAAGTTCTGA

Upstream 100 bases:

>100_bases
AGGTCAGGGGCAGGAAGTACTTCCTTAGGAAGAAGGAGTGATCCGCTTTTGTCCGCCAACTTTTTTAACCGTAGGTTTTG
AACCTCTTTTGGTGATTCTT

Downstream 100 bases:

>100_bases
CTCTCTTTTCATTTCCTCAATAGCGCGATGCTTCCCCCAAGGAGCACTAAGCCAAGGCCAAAAGCTGTTCCAAAGCCTGC
AGTGGCTACAATCCAGCCGC

Product: NADH oxidase

Products: NA

Alternate protein names: CoA-disulfide reductase; CoADR [H]

Number of amino acids: Translated: 441; Mature: 441

Protein sequence:

>441_residues
MKKTVVIIGGGAAGMSAASRIKRLKPEWDVKVFEATEWVSHAPCGVPYVVEGISPKEKLMHYPPEVFIKKRGIDLHMKAE
VIEVEEGSVRVREEDGEHTYEWDYLVFANGASPHVPPIEGLELEGVFTADLPPDAVAIRDYIEKNKVENVVIIGTGYIAI
EMAEAFVAQGKNVTLIGRSERVLRKTFDKEITDIVEEKLKAHLNLRLQELTMRIEGDGRVEKVVTDASEYPADLVIIATG
IKPNTELAKQLGVRTGETGAIWTNEKMQTSVENVYAAGDVAETRHIITGRRVWIPLAPSGNKMGYVAGSNIAGKEITFPG
VLGTSITKFLDLEIGKTGLTEAEAIKEGYDVRTAFIKAKTRPHYYPGAKEIHLKGVVDNETNRLLGVQAVGGEILPRIDA
AAAMIQAGFTTKDVFFTDLAYAPPFAPVWDPLIVLARVLKF

Sequences:

>Translated_441_residues
MKKTVVIIGGGAAGMSAASRIKRLKPEWDVKVFEATEWVSHAPCGVPYVVEGISPKEKLMHYPPEVFIKKRGIDLHMKAE
VIEVEEGSVRVREEDGEHTYEWDYLVFANGASPHVPPIEGLELEGVFTADLPPDAVAIRDYIEKNKVENVVIIGTGYIAI
EMAEAFVAQGKNVTLIGRSERVLRKTFDKEITDIVEEKLKAHLNLRLQELTMRIEGDGRVEKVVTDASEYPADLVIIATG
IKPNTELAKQLGVRTGETGAIWTNEKMQTSVENVYAAGDVAETRHIITGRRVWIPLAPSGNKMGYVAGSNIAGKEITFPG
VLGTSITKFLDLEIGKTGLTEAEAIKEGYDVRTAFIKAKTRPHYYPGAKEIHLKGVVDNETNRLLGVQAVGGEILPRIDA
AAAMIQAGFTTKDVFFTDLAYAPPFAPVWDPLIVLARVLKF
>Mature_441_residues
MKKTVVIIGGGAAGMSAASRIKRLKPEWDVKVFEATEWVSHAPCGVPYVVEGISPKEKLMHYPPEVFIKKRGIDLHMKAE
VIEVEEGSVRVREEDGEHTYEWDYLVFANGASPHVPPIEGLELEGVFTADLPPDAVAIRDYIEKNKVENVVIIGTGYIAI
EMAEAFVAQGKNVTLIGRSERVLRKTFDKEITDIVEEKLKAHLNLRLQELTMRIEGDGRVEKVVTDASEYPADLVIIATG
IKPNTELAKQLGVRTGETGAIWTNEKMQTSVENVYAAGDVAETRHIITGRRVWIPLAPSGNKMGYVAGSNIAGKEITFPG
VLGTSITKFLDLEIGKTGLTEAEAIKEGYDVRTAFIKAKTRPHYYPGAKEIHLKGVVDNETNRLLGVQAVGGEILPRIDA
AAAMIQAGFTTKDVFFTDLAYAPPFAPVWDPLIVLARVLKF

Specific function: Unknown

COG id: COG0446

COG function: function code R; Uncharacterized NAD(FAD)-dependent dehydrogenases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-III pyridine nucleotide-disulfide oxidoreductase family [H]

Homologues:

Organism=Homo sapiens, GI65787454, Length=319, Percent_Identity=26.0188087774295, Blast_Score=103, Evalue=4e-22,
Organism=Homo sapiens, GI226437568, Length=319, Percent_Identity=26.0188087774295, Blast_Score=102, Evalue=5e-22,
Organism=Homo sapiens, GI21389617, Length=319, Percent_Identity=26.0188087774295, Blast_Score=102, Evalue=5e-22,
Organism=Homo sapiens, GI50301238, Length=292, Percent_Identity=27.7397260273973, Blast_Score=67, Evalue=3e-11,
Organism=Escherichia coli, GI1789065, Length=285, Percent_Identity=25.2631578947368, Blast_Score=88, Evalue=9e-19,
Organism=Escherichia coli, GI1789765, Length=349, Percent_Identity=26.0744985673352, Blast_Score=81, Evalue=1e-16,
Organism=Escherichia coli, GI1788892, Length=286, Percent_Identity=24.1258741258741, Blast_Score=72, Evalue=1e-13,
Organism=Escherichia coli, GI87081717, Length=456, Percent_Identity=24.5614035087719, Blast_Score=67, Evalue=2e-12,
Organism=Escherichia coli, GI1789915, Length=355, Percent_Identity=25.0704225352113, Blast_Score=66, Evalue=6e-12,
Organism=Caenorhabditis elegans, GI17557007, Length=326, Percent_Identity=30.6748466257669, Blast_Score=78, Evalue=1e-14,
Organism=Caenorhabditis elegans, GI71983429, Length=319, Percent_Identity=27.8996865203762, Blast_Score=69, Evalue=7e-12,
Organism=Caenorhabditis elegans, GI71983419, Length=319, Percent_Identity=27.8996865203762, Blast_Score=68, Evalue=7e-12,
Organism=Caenorhabditis elegans, GI17559934, Length=226, Percent_Identity=25.6637168141593, Blast_Score=68, Evalue=9e-12,
Organism=Saccharomyces cerevisiae, GI6325166, Length=366, Percent_Identity=24.5901639344262, Blast_Score=64, Evalue=6e-11,
Organism=Drosophila melanogaster, GI24585130, Length=318, Percent_Identity=25.7861635220126, Blast_Score=105, Evalue=9e-23,
Organism=Drosophila melanogaster, GI24639257, Length=317, Percent_Identity=26.4984227129338, Blast_Score=100, Evalue=4e-21,
Organism=Drosophila melanogaster, GI281359715, Length=317, Percent_Identity=26.4984227129338, Blast_Score=99, Evalue=8e-21,
Organism=Drosophila melanogaster, GI281359713, Length=317, Percent_Identity=26.4984227129338, Blast_Score=99, Evalue=8e-21,
Organism=Drosophila melanogaster, GI24639250, Length=317, Percent_Identity=26.4984227129338, Blast_Score=99, Evalue=8e-21,
Organism=Drosophila melanogaster, GI18543267, Length=317, Percent_Identity=26.4984227129338, Blast_Score=99, Evalue=8e-21,
Organism=Drosophila melanogaster, GI24639252, Length=317, Percent_Identity=26.4984227129338, Blast_Score=99, Evalue=8e-21,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017758
- InterPro:   IPR016156
- InterPro:   IPR013027
- InterPro:   IPR004099
- InterPro:   IPR001327 [H]

Pfam domain/function: PF00070 Pyr_redox; PF07992 Pyr_redox_2; PF02852 Pyr_redox_dim [H]

EC number: =1.8.1.14 [H]

Molecular weight: Translated: 48402; Mature: 48402

Theoretical pI: Translated: 5.72; Mature: 5.72

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKTVVIIGGGAAGMSAASRIKRLKPEWDVKVFEATEWVSHAPCGVPYVVEGISPKEKLM
CCEEEEEEECCCHHHHHHHHHHHCCCCCCEEEEEEHHHHHCCCCCCCEEEECCCHHHHHH
HYPPEVFIKKRGIDLHMKAEVIEVEEGSVRVREEDGEHTYEWDYLVFANGASPHVPPIEG
CCCCHHEEEECCCEEEEEEEEEEECCCCEEEEECCCCEEEEEEEEEEECCCCCCCCCCCC
LELEGVFTADLPPDAVAIRDYIEKNKVENVVIIGTGYIAIEMAEAFVAQGKNVTLIGRSE
EEECEEEECCCCCCHHHHHHHHHHCCCCEEEEEECCEEEEEHHHHHHHCCCCEEEEECCH
RVLRKTFDKEITDIVEEKLKAHLNLRLQELTMRIEGDGRVEKVVTDASEYPADLVIIATG
HHHHHHHHHHHHHHHHHHHHHHHCEEEEEEEEEECCCCCEEHEECCCCCCCCEEEEEEEC
IKPNTELAKQLGVRTGETGAIWTNEKMQTSVENVYAAGDVAETRHIITGRRVWIPLAPSG
CCCCHHHHHHHCCCCCCCCEEEECHHHHHHHHHHEECCCHHHHHHEEECCEEEEEECCCC
NKMGYVAGSNIAGKEITFPGVLGTSITKFLDLEIGKTGLTEAEAIKEGYDVRTAFIKAKT
CEEEEEECCCCCCCEEECCCHHHHHHHHHHEEECCCCCCCHHHHHHCCCCEEEEEEEECC
RPHYYPGAKEIHLKGVVDNETNRLLGVQAVGGEILPRIDAAAAMIQAGFTTKDVFFTDLA
CCCCCCCCCEEEEEEEEECCCCCEEEEEECCCCHHHHHHHHHHHHHCCCCCCCEEEEHHC
YAPPFAPVWDPLIVLARVLKF
CCCCCCCHHHHHHHHHHHHCC
>Mature Secondary Structure
MKKTVVIIGGGAAGMSAASRIKRLKPEWDVKVFEATEWVSHAPCGVPYVVEGISPKEKLM
CCEEEEEEECCCHHHHHHHHHHHCCCCCCEEEEEEHHHHHCCCCCCCEEEECCCHHHHHH
HYPPEVFIKKRGIDLHMKAEVIEVEEGSVRVREEDGEHTYEWDYLVFANGASPHVPPIEG
CCCCHHEEEECCCEEEEEEEEEEECCCCEEEEECCCCEEEEEEEEEEECCCCCCCCCCCC
LELEGVFTADLPPDAVAIRDYIEKNKVENVVIIGTGYIAIEMAEAFVAQGKNVTLIGRSE
EEECEEEECCCCCCHHHHHHHHHHCCCCEEEEEECCEEEEEHHHHHHHCCCCEEEEECCH
RVLRKTFDKEITDIVEEKLKAHLNLRLQELTMRIEGDGRVEKVVTDASEYPADLVIIATG
HHHHHHHHHHHHHHHHHHHHHHHCEEEEEEEEEECCCCCEEHEECCCCCCCCEEEEEEEC
IKPNTELAKQLGVRTGETGAIWTNEKMQTSVENVYAAGDVAETRHIITGRRVWIPLAPSG
CCCCHHHHHHHCCCCCCCCEEEECHHHHHHHHHHEECCCHHHHHHEEECCEEEEEECCCC
NKMGYVAGSNIAGKEITFPGVLGTSITKFLDLEIGKTGLTEAEAIKEGYDVRTAFIKAKT
CEEEEEECCCCCCCEEECCCHHHHHHHHHHEEECCCCCCCHHHHHHCCCCEEEEEEEECC
RPHYYPGAKEIHLKGVVDNETNRLLGVQAVGGEILPRIDAAAAMIQAGFTTKDVFFTDLA
CCCCCCCCCEEEEEEEEECCCCCEEEEEECCCCHHHHHHHHHHHHHCCCCCCCEEEEHHC
YAPPFAPVWDPLIVLARVLKF
CCCCCCCHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA