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The map label for this gene is gcdB [H]

Identifier: 212223183

GI number: 212223183

Start: 33235

End: 34362

Strand: Reverse

Name: gcdB [H]

Synonym: TON_0038

Alternate gene names: 212223183

Gene position: 34362-33235 (Counterclockwise)

Preceding gene: 212223184

Following gene: 212223182

Centisome position: 1.86

GC content: 55.59

Gene sequence:

>1128_bases
ATGGCCGGACTGGAGCAGGCAATAATCGAATTCATCGAGAGCATGGGGCTTCTCCATCTAACTGTTGGCAATGTAATAAT
GATACTCGTCGGTCTGATACTCGTCTATCTCGCCATCAGATATGAGATGGAGCCCCTGCTCCTCCTCCCGATAGGCATAA
GTGCCGTCATCGTCAACCTGCCGCTCACAGGCATAACCGACGAACCACATGGACTGTTCTATCTTATCCACCACTACCTC
ATAAGCACAGAGATAGTGCCACTGCTGATATTCTTCGGACTGGGGGCGATGACAGACTTCGGGCCGATGATAGCAGACCC
CAAGACGGCTCTGCTCGGCGCTGCCGCTCAGATAGGTGTTTTCGTTGCTATGCTGAGCGCGGTGCTGCTCGGTTTCACCC
TGCCTGAGGCGGCTTCGATAGGTATCATCGGCGGTGCCGACGGACCGACGACCATATACCTCACCACCAAGCTGGCTCCA
CACCTTCTCGGAGCGACTGCCGTGGCGGCTTACTCTTACATGAGCCTCGTCCCGCTTATCCAGCCGCCTATCATCAAGGC
CATGACCAGTAAGGAGGAAAGGAAAATCAGAATGGAGCAGCTCAGACCCGTCTCCAAGAGGGAGAAGATAATGTTCCCCA
TAATCACTGCTATCGTCATCAGCCTCCTCGTTCCAAGCGCCGGGCCGCTCATTGGAATGCTCATGATAGGCAACCTCTTC
AGGGAGAGCGGCGTCGTTGAGAGGCTGAGCAAAGCTGCCCAGGAGGAGCTAATGAACATCGTCACCATCTTCCTCGGGCT
TGGCGTCGGCTCAACGATGAGGGCTGAGACTTTCCTCACGGCGAAGACCCTTATGATACTTGGCCTTGGTGTCGTCGCCT
TCGCCTCTGCAACCGCTGGAGGAGTGCTCCTCGGGAAGATTATGATGAAGCTTAGCGGCGGCAAGATAAACCCGATGATT
GGAGCGGCTGGAGTTTCGGCAGTTCCAATGAGCGCCAGGGTTGTCCAGCGCTTGGCGAGTGAGGAAGACCCAGGGAACTT
CATACTCATGCACGCAATGGGTCCGAACGTCGCTGGAGTTATAGGGACTGCCGTCGTCGCCGGAGTTCTTCTCTCAGTTC
TAGGCTGA

Upstream 100 bases:

>100_bases
AATCCCAGCACCAAAAGACGGAACAATAAAGAAAATCCTCATCAAAGAAGGCCAAACCGTCGACACCGGACAACCACTAA
TCGAACTCGGGTGATGGAGA

Downstream 100 bases:

>100_bases
CCTTTTTCTTCAAATTTTTGATGAGCCTAATGAAAACCTTAAATAGGAGAAGGACGCTTTAACCTAAAGCGGTGGTGAAG
AAAATGCGTGTAAAGACTTT

Product: methylmalonyl-CoA decarboxylase beta chain

Products: NA

Alternate protein names: Carboxylyase [H]

Number of amino acids: Translated: 375; Mature: 374

Protein sequence:

>375_residues
MAGLEQAIIEFIESMGLLHLTVGNVIMILVGLILVYLAIRYEMEPLLLLPIGISAVIVNLPLTGITDEPHGLFYLIHHYL
ISTEIVPLLIFFGLGAMTDFGPMIADPKTALLGAAAQIGVFVAMLSAVLLGFTLPEAASIGIIGGADGPTTIYLTTKLAP
HLLGATAVAAYSYMSLVPLIQPPIIKAMTSKEERKIRMEQLRPVSKREKIMFPIITAIVISLLVPSAGPLIGMLMIGNLF
RESGVVERLSKAAQEELMNIVTIFLGLGVGSTMRAETFLTAKTLMILGLGVVAFASATAGGVLLGKIMMKLSGGKINPMI
GAAGVSAVPMSARVVQRLASEEDPGNFILMHAMGPNVAGVIGTAVVAGVLLSVLG

Sequences:

>Translated_375_residues
MAGLEQAIIEFIESMGLLHLTVGNVIMILVGLILVYLAIRYEMEPLLLLPIGISAVIVNLPLTGITDEPHGLFYLIHHYL
ISTEIVPLLIFFGLGAMTDFGPMIADPKTALLGAAAQIGVFVAMLSAVLLGFTLPEAASIGIIGGADGPTTIYLTTKLAP
HLLGATAVAAYSYMSLVPLIQPPIIKAMTSKEERKIRMEQLRPVSKREKIMFPIITAIVISLLVPSAGPLIGMLMIGNLF
RESGVVERLSKAAQEELMNIVTIFLGLGVGSTMRAETFLTAKTLMILGLGVVAFASATAGGVLLGKIMMKLSGGKINPMI
GAAGVSAVPMSARVVQRLASEEDPGNFILMHAMGPNVAGVIGTAVVAGVLLSVLG
>Mature_374_residues
AGLEQAIIEFIESMGLLHLTVGNVIMILVGLILVYLAIRYEMEPLLLLPIGISAVIVNLPLTGITDEPHGLFYLIHHYLI
STEIVPLLIFFGLGAMTDFGPMIADPKTALLGAAAQIGVFVAMLSAVLLGFTLPEAASIGIIGGADGPTTIYLTTKLAPH
LLGATAVAAYSYMSLVPLIQPPIIKAMTSKEERKIRMEQLRPVSKREKIMFPIITAIVISLLVPSAGPLIGMLMIGNLFR
ESGVVERLSKAAQEELMNIVTIFLGLGVGSTMRAETFLTAKTLMILGLGVVAFASATAGGVLLGKIMMKLSGGKINPMIG
AAGVSAVPMSARVVQRLASEEDPGNFILMHAMGPNVAGVIGTAVVAGVLLSVLG

Specific function: Tunnel subunit of the primary sodium pump glutaconyl-CoA decarboxylase (GCD) [H]

COG id: COG1883

COG function: function code C; Na+-transporting methylmalonyl-CoA/oxaloacetate decarboxylase, beta subunit

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the gcdB/mmdB/oadB family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005661 [H]

Pfam domain/function: PF03977 OAD_beta [H]

EC number: =4.1.1.70 [H]

Molecular weight: Translated: 39318; Mature: 39187

Theoretical pI: Translated: 6.81; Mature: 6.81

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
5.9 %Met     (Translated Protein)
5.9 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
5.6 %Met     (Mature Protein)
5.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAGLEQAIIEFIESMGLLHLTVGNVIMILVGLILVYLAIRYEMEPLLLLPIGISAVIVNL
CCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCHHHHHEEC
PLTGITDEPHGLFYLIHHYLISTEIVPLLIFFGLGAMTDFGPMIADPKTALLGAAAQIGV
CCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHH
FVAMLSAVLLGFTLPEAASIGIIGGADGPTTIYLTTKLAPHLLGATAVAAYSYMSLVPLI
HHHHHHHHHHHCCCCCCCCEEEEECCCCCEEEEEECCHHHHHHHHHHHHHHHHHHHHHHC
QPPIIKAMTSKEERKIRMEQLRPVSKREKIMFPIITAIVISLLVPSAGPLIGMLMIGNLF
CCHHHHHHCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHH
RESGVVERLSKAAQEELMNIVTIFLGLGVGSTMRAETFLTAKTLMILGLGVVAFASATAG
HHCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCC
GVLLGKIMMKLSGGKINPMIGAAGVSAVPMSARVVQRLASEEDPGNFILMHAMGPNVAGV
HHHHHHHHHHHCCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCCCCCEEEEEECCCCHHHH
IGTAVVAGVLLSVLG
HHHHHHHHHHHHHHC
>Mature Secondary Structure 
AGLEQAIIEFIESMGLLHLTVGNVIMILVGLILVYLAIRYEMEPLLLLPIGISAVIVNL
CCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCHHHHHEEC
PLTGITDEPHGLFYLIHHYLISTEIVPLLIFFGLGAMTDFGPMIADPKTALLGAAAQIGV
CCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHH
FVAMLSAVLLGFTLPEAASIGIIGGADGPTTIYLTTKLAPHLLGATAVAAYSYMSLVPLI
HHHHHHHHHHHCCCCCCCCEEEEECCCCCEEEEEECCHHHHHHHHHHHHHHHHHHHHHHC
QPPIIKAMTSKEERKIRMEQLRPVSKREKIMFPIITAIVISLLVPSAGPLIGMLMIGNLF
CCHHHHHHCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHH
RESGVVERLSKAAQEELMNIVTIFLGLGVGSTMRAETFLTAKTLMILGLGVVAFASATAG
HHCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCC
GVLLGKIMMKLSGGKINPMIGAAGVSAVPMSARVVQRLASEEDPGNFILMHAMGPNVAGV
HHHHHHHHHHHCCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCCCCCEEEEEECCCCHHHH
IGTAVVAGVLLSVLG
HHHHHHHHHHHHHHC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 10027965 [H]