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The map label for this gene is appB [H]

Identifier: 209554414

GI number: 209554414

Start: 790619

End: 791764

Strand: Reverse

Name: appB [H]

Synonym: UUR10_0658

Alternate gene names: 209554414

Gene position: 791764-790619 (Counterclockwise)

Preceding gene: 209554348

Following gene: 209554631

Centisome position: 90.54

GC content: 30.89

Gene sequence:

>1146_bases
ATGAATCAGAAAAATAGTCTTGAGTCTAATTCATCACAAAGTAATTATGGTGAATTACCACAACAATCGACTACATTAAG
CCAAAAAAAGCGGGTTAATTATTCATTTAGTAATAATTTCGTTATTTTTGGTGGTGGTCGTTCACTAAAAACAGCAGCTG
ATCGTGATCATGTTGTTGATCCATTAATTGATTTCTTCACTTTTGATTCAAAGTTTATGACATTTATCACTAAATCTTTG
AAATTAATTGCTGAATTCTTTTTATTGGCTTGAATTGTAATTACAATTACATTCTTCTTAATTAACTCAGTACCTGGAGA
ATCTGCTTTAACAATTGGAATTACATCTCCAGAAGCAAAAAAAGCTATCTTAGCACAATATGGACTAGATCGTCCGCTTG
GCGTTCGTTATGCTGATTATTTAGCAAATATCTTTAGAGGAGAATTTGGGGTAAGTACTTCAATTCGTCCAGGGGTTGAA
ATTAATTCATTTATTTGATCTCGTTATCTAGTGAGTTTTGCTGTAGGGATCTTCTCAGTGTTATTAACACTAGTAATTGG
AATCCCTTTAGGTATTTTTGTTGGACGTAAACCAGGAGGGGTATTAGATAGTGTATCAACTGTGATTATTTCCATAATTT
CAGCTGTACCATCACTTGTGTTTGGTTTAATCCTACTATTAATTGGTAAAGAAGTTGGATTACCATTTACATTCGATATT
AATAATTTTGTAACCTATATCTTACCAGGATTAGCGTTATCACTTGGTTCAATTATTGTTTATGTACAATATATTAAAGT
TGAAATGAATCGTGAGCTAAACTCAATGCATGCAAAATTTGCTTACTTAAAAGGGGCAACTGTTAATCGTTTTGTATGAT
TACATGCTTTAAAACCATCATTATTCCCAATTGCAACATTCTTCCCATTTGTAATTTTAGGATCATTCGTTGGAGCATTG
TTTATTGAACAAATTTTCCAAATTCCTGGATCAGGTTCATTATTCTTTGAAGCAATTATTTCAAAAGATTACAACGTAAT
TTTATTATTAGTAATTATTTATTCATTAATTACAATTATTGGTTATACAATTCGGGATGCTTTATATCAAATTATTGACC
CACGTATTAGAAGAGGAGGAAAATAG

Upstream 100 bases:

>100_bases
TACAATCATTACATTGCCTAGTTTTATTTATGCACTAGCTTGTATGATTGCTTATATTGTAAAAACAGTACAATCAACTA
CTTAAAAATAGGAGTTTTAT

Downstream 100 bases:

>100_bases
GCTTATGGCTAAGTTTGGACAATATTTAAAAGAAAAATCAAAAAGTCTTGCTTCATCATTTGTTGATGAACTAGCTTCTG
ATGCACCAAATAAATTTTTA

Product: oligopeptide transport system permease protein

Products: ADP; phosphate; oligopeptides [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 381; Mature: 381

Protein sequence:

>381_residues
MNQKNSLESNSSQSNYGELPQQSTTLSQKKRVNYSFSNNFVIFGGGRSLKTAADRDHVVDPLIDFFTFDSKFMTFITKSL
KLIAEFFLLAWIVITITFFLINSVPGESALTIGITSPEAKKAILAQYGLDRPLGVRYADYLANIFRGEFGVSTSIRPGVE
INSFIWSRYLVSFAVGIFSVLLTLVIGIPLGIFVGRKPGGVLDSVSTVIISIISAVPSLVFGLILLLIGKEVGLPFTFDI
NNFVTYILPGLALSLGSIIVYVQYIKVEMNRELNSMHAKFAYLKGATVNRFVWLHALKPSLFPIATFFPFVILGSFVGAL
FIEQIFQIPGSGSLFFEAIISKDYNVILLLVIIYSLITIIGYTIRDALYQIIDPRIRRGGK

Sequences:

>Translated_381_residues
MNQKNSLESNSSQSNYGELPQQSTTLSQKKRVNYSFSNNFVIFGGGRSLKTAADRDHVVDPLIDFFTFDSKFMTFITKSL
KLIAEFFLLA*IVITITFFLINSVPGESALTIGITSPEAKKAILAQYGLDRPLGVRYADYLANIFRGEFGVSTSIRPGVE
INSFI*SRYLVSFAVGIFSVLLTLVIGIPLGIFVGRKPGGVLDSVSTVIISIISAVPSLVFGLILLLIGKEVGLPFTFDI
NNFVTYILPGLALSLGSIIVYVQYIKVEMNRELNSMHAKFAYLKGATVNRFV*LHALKPSLFPIATFFPFVILGSFVGAL
FIEQIFQIPGSGSLFFEAIISKDYNVILLLVIIYSLITIIGYTIRDALYQIIDPRIRRGGK
>Mature_381_residues
MNQKNSLESNSSQSNYGELPQQSTTLSQKKRVNYSFSNNFVIFGGGRSLKTAADRDHVVDPLIDFFTFDSKFMTFITKSL
KLIAEFFLLA*IVITITFFLINSVPGESALTIGITSPEAKKAILAQYGLDRPLGVRYADYLANIFRGEFGVSTSIRPGVE
INSFI*SRYLVSFAVGIFSVLLTLVIGIPLGIFVGRKPGGVLDSVSTVIISIISAVPSLVFGLILLLIGKEVGLPFTFDI
NNFVTYILPGLALSLGSIIVYVQYIKVEMNRELNSMHAKFAYLKGATVNRFV*LHALKPSLFPIATFFPFVILGSFVGAL
FIEQIFQIPGSGSLFFEAIISKDYNVILLLVIIYSLITIIGYTIRDALYQIIDPRIRRGGK

Specific function: This protein is a component of an oligopeptide permease, a binding protein-dependent transport system. This APP system can completely substitute for the OPP system in both sporulation and genetic competence, though, unlike OPP, is incapable of transportin

COG id: COG0601

COG function: function code EP; ABC-type dipeptide/oligopeptide/nickel transport systems, permease components

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transmembrane type-1 domain [H]

Homologues:

Organism=Escherichia coli, GI1787497, Length=311, Percent_Identity=30.5466237942122, Blast_Score=115, Evalue=4e-27,
Organism=Escherichia coli, GI1789965, Length=341, Percent_Identity=24.9266862170088, Blast_Score=111, Evalue=7e-26,
Organism=Escherichia coli, GI1787053, Length=310, Percent_Identity=28.3870967741935, Blast_Score=106, Evalue=3e-24,
Organism=Escherichia coli, GI1788504, Length=285, Percent_Identity=27.3684210526316, Blast_Score=89, Evalue=4e-19,
Organism=Escherichia coli, GI1789888, Length=268, Percent_Identity=25.7462686567164, Blast_Score=77, Evalue=1e-15,
Organism=Escherichia coli, GI1787761, Length=325, Percent_Identity=26.4615384615385, Blast_Score=68, Evalue=1e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000515 [H]

Pfam domain/function: PF00528 BPD_transp_1 [H]

EC number: NA

Molecular weight: Translated: 41600; Mature: 41600

Theoretical pI: Translated: 9.87; Mature: 9.87

Prosite motif: PS50928 ABC_TM1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.0 %Met     (Translated Protein)
1.0 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
1.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNQKNSLESNSSQSNYGELPQQSTTLSQKKRVNYSFSNNFVIFGGGRSLKTAADRDHVVD
CCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHCCEEECCCEEEEECCCCCCCCCCCHHHHH
PLIDFFTFDSKFMTFITKSLKLIAEFFLLAIVITITFFLINSVPGESALTIGITSPEAKK
HHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEECCCHHHH
AILAQYGLDRPLGVRYADYLANIFRGEFGVSTSIRPGVEINSFISRYLVSFAVGIFSVLL
HHHHHHCCCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHH
TLVIGIPLGIFVGRKPGGVLDSVSTVIISIISAVPSLVFGLILLLIGKEVGLPFTFDINN
HHHHHHHHHHEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEHHH
FVTYILPGLALSLGSIIVYVQYIKVEMNRELNSMHAKFAYLKGATVNRFVLHALKPSLFP
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCHHH
IATFFPFVILGSFVGALFIEQIFQIPGSGSLFFEAIISKDYNVILLLVIIYSLITIIGYT
HHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHH
IRDALYQIIDPRIRRGGK
HHHHHHHHHCHHHHCCCC
>Mature Secondary Structure
MNQKNSLESNSSQSNYGELPQQSTTLSQKKRVNYSFSNNFVIFGGGRSLKTAADRDHVVD
CCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHCCEEECCCEEEEECCCCCCCCCCCHHHHH
PLIDFFTFDSKFMTFITKSLKLIAEFFLLAIVITITFFLINSVPGESALTIGITSPEAKK
HHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEECCCHHHH
AILAQYGLDRPLGVRYADYLANIFRGEFGVSTSIRPGVEINSFISRYLVSFAVGIFSVLL
HHHHHHCCCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHH
TLVIGIPLGIFVGRKPGGVLDSVSTVIISIISAVPSLVFGLILLLIGKEVGLPFTFDINN
HHHHHHHHHHEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEHHH
FVTYILPGLALSLGSIIVYVQYIKVEMNRELNSMHAKFAYLKGATVNRFVLHALKPSLFP
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCHHH
IATFFPFVILGSFVGALFIEQIFQIPGSGSLFFEAIISKDYNVILLLVIIYSLITIIGYT
HHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHH
IRDALYQIIDPRIRRGGK
HHHHHHHHHCHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; oligopeptides [Periplasm]; H2O [C]

Specific reaction: ATP + oligopeptides [Periplasm] + H2O = ADP + phosphate + oligopeptides [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7997159; 9384377 [H]