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The map label for this gene is rlmH [H]

Identifier: 209554168

GI number: 209554168

Start: 201646

End: 202125

Strand: Reverse

Name: rlmH [H]

Synonym: UUR10_0171

Alternate gene names: 209554168

Gene position: 202125-201646 (Counterclockwise)

Preceding gene: 209554425

Following gene: 209554624

Centisome position: 23.11

GC content: 24.17

Gene sequence:

>480_bases
ATGATAATAAAAATTATAAGTGTAGGTAAATTAAAACAAACTGGTTTTGTTAATTTAGTTAATGATTATTTAAAACGAAT
TAACTATTATTTAAAATGTCAAGAAATTGTTGTTAATGATGAGCCTGAGCCAACCCAAATTTCAACTAAATTATTAGAAC
AAATTAAAGATAAAGAAGCTAATAGAATTCTAAAAAACATTAATCAAAATGATTTTGTAATTGCTTTAATTATTGAAGGC
AAAATTATTAGTAGTGAAATGTTAGCTGAAAATTTACAAAATTGATTAAATGCATCATATCCTAATATTTGCTTTGTAAT
TGGTGGTTCTAATGGATTGCATGAAAAAATTTATGAACGTGCTAACTATCACTTATCATTGTCAAAAATGACTTTCGCAC
ATGGTTTAGCAAAAGTCATGGTTTGTGAACAAATATATCGAGCACTTAGTATTTTAAATAATGGAAAATATCATAAATAA

Upstream 100 bases:

>100_bases
TTGCATTCATTTTAAAATTAGCAATAATGTATTTCATTTTAACCATTCTCCCTTATAATCTTAAATAGATTATAATCAAA
AAATGGGTTGTTTATTAAAG

Downstream 100 bases:

>100_bases
ATTATGCGTTTTGATCATATTCTTCAAATACTGAACACCCTTGTTGATCATATTTAATTAAATTAATAAATTTACCAATT
TCAGGGATAATATTTTGTAA

Product: conserved hypothetical protein TIGR00246

Products: NA

Alternate protein names: 23S rRNA m3Psi1915 methyltransferase; rRNA (pseudouridine-N3-)-methyltransferase rlmH [H]

Number of amino acids: Translated: 159; Mature: 159

Protein sequence:

>159_residues
MIIKIISVGKLKQTGFVNLVNDYLKRINYYLKCQEIVVNDEPEPTQISTKLLEQIKDKEANRILKNINQNDFVIALIIEG
KIISSEMLAENLQNWLNASYPNICFVIGGSNGLHEKIYERANYHLSLSKMTFAHGLAKVMVCEQIYRALSILNNGKYHK

Sequences:

>Translated_159_residues
MIIKIISVGKLKQTGFVNLVNDYLKRINYYLKCQEIVVNDEPEPTQISTKLLEQIKDKEANRILKNINQNDFVIALIIEG
KIISSEMLAENLQN*LNASYPNICFVIGGSNGLHEKIYERANYHLSLSKMTFAHGLAKVMVCEQIYRALSILNNGKYHK
>Mature_159_residues
MIIKIISVGKLKQTGFVNLVNDYLKRINYYLKCQEIVVNDEPEPTQISTKLLEQIKDKEANRILKNINQNDFVIALIIEG
KIISSEMLAENLQN*LNASYPNICFVIGGSNGLHEKIYERANYHLSLSKMTFAHGLAKVMVCEQIYRALSILNNGKYHK

Specific function: Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA [H]

COG id: COG1576

COG function: function code S; Uncharacterized conserved protein

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the RNA methyltransferase rlmH family [H]

Homologues:

Organism=Escherichia coli, GI1786855, Length=162, Percent_Identity=29.6296296296296, Blast_Score=74, Evalue=5e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003742 [H]

Pfam domain/function: PF02590 SPOUT_MTase [H]

EC number: NA

Molecular weight: Translated: 18011; Mature: 18011

Theoretical pI: Translated: 9.05; Mature: 9.05

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIIKIISVGKLKQTGFVNLVNDYLKRINYYLKCQEIVVNDEPEPTQISTKLLEQIKDKEA
CEEEEEECCCCCCCCHHHHHHHHHHHHHHHHEEEEEEECCCCCCHHHHHHHHHHHHHHHH
NRILKNINQNDFVIALIIEGKIISSEMLAENLQNLNASYPNICFVIGGSNGLHEKIYERA
HHHHHHCCCCCEEEEEEECCEEHHHHHHHHHHHHCCCCCCCEEEEEECCCCHHHHHHHHC
NYHLSLSKMTFAHGLAKVMVCEQIYRALSILNNGKYHK
CCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure
MIIKIISVGKLKQTGFVNLVNDYLKRINYYLKCQEIVVNDEPEPTQISTKLLEQIKDKEA
CEEEEEECCCCCCCCHHHHHHHHHHHHHHHHEEEEEEECCCCCCHHHHHHHHHHHHHHHH
NRILKNINQNDFVIALIIEGKIISSEMLAENLQNLNASYPNICFVIGGSNGLHEKIYERA
HHHHHHCCCCCEEEEEEECCEEHHHHHHHHHHHHCCCCCCCEEEEEECCCCHHHHHHHHC
NYHLSLSKMTFAHGLAKVMVCEQIYRALSILNNGKYHK
CCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA