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The map label for this gene is trpS [H]

Identifier: 209554624

GI number: 209554624

Start: 198625

End: 199626

Strand: Reverse

Name: trpS [H]

Synonym: UUR10_0166

Alternate gene names: 209554624

Gene position: 199626-198625 (Counterclockwise)

Preceding gene: 209554168

Following gene: 209554242

Centisome position: 22.83

GC content: 28.04

Gene sequence:

>1002_bases
ATGAAACGATTAATTTCAGGGATTCAACCAACAAATAATTTAACATTAGGAAATTATTTAGGAGCAATTAAAAATTTTGT
AGATTTACAAAATGATTATGAAGTGTTTTTGTTTGTTGCAGACCTTCATTCACTAACACCAAACATTTTTGATAATACTA
ACTTTTTTGCTACTAAGCGTCAAATTATAGCTACATATTTAGCTGCAGGTATTGATCCTAAAAAAACATGTTTATTTTAT
CAATCAGATATTTTAGCAATTCCATTATTATCACATATACTACTATGTTCAACAAGTATTGGTGAACTTACACGTATGAC
TCAATTTAAAGATAAAAGTGCTAAAGCTACAAAAATGGCTAACAACACTGAAATGATTCCTTCAGGATTACTAACATACC
CAGCATTAATGGCTGCTGATATTTTAGCTTTTAATGCTGATGTTGTTCCTGTTGGTCAAGATCAAAAACAACATTTAGAA
TTAACAAGAACGCTAGCTGATCGCTTTAATAAAAGATATGGACAAACTTTTAAATTACCTCAAGTTTATATTCCAAAAAT
TGGCGCAAAAATTATGGATTTATTAGATCCAAGCGTTAAGATGTCAAAATCCTCAAAAAATCCAAAGGGCGTTATTTTTT
TAAATGATTCACGTGAACAAATTATTAAAAAAATTAAAGGCGCTTTAACAGATAACTTAAACCAAGTTAAATATGATGTT
GAACAACAACCAAGTGTAAGTAATTTAATTACAATATATGCTTGTTTAACTAATTTAACTTTTGCAGAAATTGAAACAAA
ATATAATCAACAAAATTATGGCGTTTTTAAAAATGATCTAGCTAATATTGTTGCTGATTTTCTTGAAAACCTACAACAAA
AAATTTCTTATTGATTAAATAGCCCAGAATTAGATATAATGATAGACAATAGTTGCGAGCGAGCTAATGATGTTGCAAAC
CAAAATGTGCAACTTGTCTTAAAACAAATGCAACTAAAATAA

Upstream 100 bases:

>100_bases
CAATTCTAAATTTACTTATATAATAAATAAGTATACAAAAAAAACATTAATTTTAAATGCTTAATTACAAAAAACAATTT
AATAATAAAAGAGAGAACGT

Downstream 100 bases:

>100_bases
TGGGTATATAATGAGGTAAAAATTAATGGGAAAAAACGATAAATATTTGATTGCTTGTGATTTAGATGGAACACTTTTAA
ATAATGAAAGTGATATCTCA

Product: tryptophanyl-tRNA synthetase

Products: NA

Alternate protein names: Tryptophan--tRNA ligase; TrpRS [H]

Number of amino acids: Translated: 333; Mature: 333

Protein sequence:

>333_residues
MKRLISGIQPTNNLTLGNYLGAIKNFVDLQNDYEVFLFVADLHSLTPNIFDNTNFFATKRQIIATYLAAGIDPKKTCLFY
QSDILAIPLLSHILLCSTSIGELTRMTQFKDKSAKATKMANNTEMIPSGLLTYPALMAADILAFNADVVPVGQDQKQHLE
LTRTLADRFNKRYGQTFKLPQVYIPKIGAKIMDLLDPSVKMSKSSKNPKGVIFLNDSREQIIKKIKGALTDNLNQVKYDV
EQQPSVSNLITIYACLTNLTFAEIETKYNQQNYGVFKNDLANIVADFLENLQQKISYWLNSPELDIMIDNSCERANDVAN
QNVQLVLKQMQLK

Sequences:

>Translated_333_residues
MKRLISGIQPTNNLTLGNYLGAIKNFVDLQNDYEVFLFVADLHSLTPNIFDNTNFFATKRQIIATYLAAGIDPKKTCLFY
QSDILAIPLLSHILLCSTSIGELTRMTQFKDKSAKATKMANNTEMIPSGLLTYPALMAADILAFNADVVPVGQDQKQHLE
LTRTLADRFNKRYGQTFKLPQVYIPKIGAKIMDLLDPSVKMSKSSKNPKGVIFLNDSREQIIKKIKGALTDNLNQVKYDV
EQQPSVSNLITIYACLTNLTFAEIETKYNQQNYGVFKNDLANIVADFLENLQQKISY*LNSPELDIMIDNSCERANDVAN
QNVQLVLKQMQLK
>Mature_333_residues
MKRLISGIQPTNNLTLGNYLGAIKNFVDLQNDYEVFLFVADLHSLTPNIFDNTNFFATKRQIIATYLAAGIDPKKTCLFY
QSDILAIPLLSHILLCSTSIGELTRMTQFKDKSAKATKMANNTEMIPSGLLTYPALMAADILAFNADVVPVGQDQKQHLE
LTRTLADRFNKRYGQTFKLPQVYIPKIGAKIMDLLDPSVKMSKSSKNPKGVIFLNDSREQIIKKIKGALTDNLNQVKYDV
EQQPSVSNLITIYACLTNLTFAEIETKYNQQNYGVFKNDLANIVADFLENLQQKISY*LNSPELDIMIDNSCERANDVAN
QNVQLVLKQMQLK

Specific function: Unknown

COG id: COG0180

COG function: function code J; Tryptophanyl-tRNA synthetase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I aminoacyl-tRNA synthetase family [H]

Homologues:

Organism=Homo sapiens, GI7710154, Length=333, Percent_Identity=36.9369369369369, Blast_Score=202, Evalue=2e-52,
Organism=Homo sapiens, GI41352700, Length=185, Percent_Identity=44.8648648648649, Blast_Score=145, Evalue=4e-35,
Organism=Escherichia coli, GI1789786, Length=326, Percent_Identity=41.1042944785276, Blast_Score=252, Evalue=2e-68,
Organism=Caenorhabditis elegans, GI71982800, Length=328, Percent_Identity=36.5853658536585, Blast_Score=197, Evalue=6e-51,
Organism=Caenorhabditis elegans, GI71982793, Length=330, Percent_Identity=36.3636363636364, Blast_Score=195, Evalue=2e-50,
Organism=Saccharomyces cerevisiae, GI6320474, Length=346, Percent_Identity=37.5722543352601, Blast_Score=192, Evalue=6e-50,
Organism=Drosophila melanogaster, GI24666151, Length=338, Percent_Identity=35.5029585798817, Blast_Score=189, Evalue=3e-48,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001412
- InterPro:   IPR002305
- InterPro:   IPR014729
- InterPro:   IPR002306 [H]

Pfam domain/function: PF00579 tRNA-synt_1b [H]

EC number: =6.1.1.2 [H]

Molecular weight: Translated: 37343; Mature: 37343

Theoretical pI: Translated: 8.54; Mature: 8.54

Prosite motif: PS00178 AA_TRNA_LIGASE_I

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKRLISGIQPTNNLTLGNYLGAIKNFVDLQNDYEVFLFVADLHSLTPNIFDNTNFFATKR
CCHHHCCCCCCCCCCHHHHHHHHHHHHHCCCCCEEEEEEEHHHHHCCCCCCCCCHHHHHH
QIIATYLAAGIDPKKTCLFYQSDILAIPLLSHILLCSTSIGELTRMTQFKDKSAKATKMA
HHHHHHHHHCCCCHHEEEEECCCHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCHHHHHHC
NNTEMIPSGLLTYPALMAADILAFNADVVPVGQDQKQHLELTRTLADRFNKRYGQTFKLP
CCCCCCCCHHHHHHHHHHHHHHHHCCCEEECCCCHHHHHHHHHHHHHHHHHHHCCCCCCC
QVYIPKIGAKIMDLLDPSVKMSKSSKNPKGVIFLNDSREQIIKKIKGALTDNLNQVKYDV
CHHHHHHHHHHHHHHCCCHHHCCCCCCCCEEEEECCCHHHHHHHHHHHHHCCHHHHEECC
EQQPSVSNLITIYACLTNLTFAEIETKYNQQNYGVFKNDLANIVADFLENLQQKISYLNS
CCCCCHHHHHHHHHHHHCCHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCC
PELDIMIDNSCERANDVANQNVQLVLKQMQLK
CCEEEEECCCCHHHHHHHCCHHHHHHHHHHCC
>Mature Secondary Structure
MKRLISGIQPTNNLTLGNYLGAIKNFVDLQNDYEVFLFVADLHSLTPNIFDNTNFFATKR
CCHHHCCCCCCCCCCHHHHHHHHHHHHHCCCCCEEEEEEEHHHHHCCCCCCCCCHHHHHH
QIIATYLAAGIDPKKTCLFYQSDILAIPLLSHILLCSTSIGELTRMTQFKDKSAKATKMA
HHHHHHHHHCCCCHHEEEEECCCHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCHHHHHHC
NNTEMIPSGLLTYPALMAADILAFNADVVPVGQDQKQHLELTRTLADRFNKRYGQTFKLP
CCCCCCCCHHHHHHHHHHHHHHHHCCCEEECCCCHHHHHHHHHHHHHHHHHHHCCCCCCC
QVYIPKIGAKIMDLLDPSVKMSKSSKNPKGVIFLNDSREQIIKKIKGALTDNLNQVKYDV
CHHHHHHHHHHHHHHCCCHHHCCCCCCCCEEEEECCCHHHHHHHHHHHHHCCHHHHEECC
EQQPSVSNLITIYACLTNLTFAEIETKYNQQNYGVFKNDLANIVADFLENLQQKISYLNS
CCCCCHHHHHHHHHHHHCCHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCC
PELDIMIDNSCERANDVANQNVQLVLKQMQLK
CCEEEEECCCCHHHHHHHCCHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11048724 [H]