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The map label for this gene is ispE [H]

Identifier: 209554027

GI number: 209554027

Start: 870977

End: 871774

Strand: Reverse

Name: ispE [H]

Synonym: UUR10_0705

Alternate gene names: 209554027

Gene position: 871774-870977 (Counterclockwise)

Preceding gene: 209554601

Following gene: 209554403

Centisome position: 99.69

GC content: 25.56

Gene sequence:

>798_bases
ATGAAAGTAAAATCATTCGCAAAAATTGATTTAGGATATAGTGTTTACAAAAAACGAAAAAACATTACAAAACACGATTT
CGAATCAATTTTTATACTTGTTGAAAGCGTTTATGATGACATTGAAATTATTAAAATTGACAAAAACGTTGATGATGTGC
ACTACTATAATGAAACAAATGAAATCTATGTTTATAGTCGTTTAGTTTATAAAACATTAGAATGAATTCGCCAAACTTAT
CGCATTAAAAACCACTACCGAATTAACATTAAAAAAAGAATACCAATTGGAGCAGGATTAGGTGGAGGTTCATCAAATGC
TGCAGTTATTATGAAATCTATTTTAGAACTTGAAGGTATTAAAGAAATTAACTACAAAGATGTTGTTAATAAACTAGGCG
CTGATATTCCCTTCTTTTTATCAGGTTATAAAACAGCTTATGTAAGTGATTGTGGTAGTACGCTTGAAGATTTGAGTGGT
CAATTTAAATTAAGTTATGAAGTTCATTTAATGAATGTTAATGTAAACACAAAATTAGTGTTTGAAAAATTTGATGATAA
TCAATGACATGTTATTAAAAATAACTTTAAAACAATTATTAAGAATTTAAAAGAGAATATTGTAACTAATATATATAATG
ATTTACAAGAACATTGTTTTGAGTTATATCCTAATATTAGATATAAATATAACGAATTATTGAGAGAGGGTTTTTATACA
ATTTTAAGCGGAGCAGGTAGCTCATTTATTTGCATAAAATTAAAAGATAAGGAAAATCAAGTTATTCATGAAAATTAG

Upstream 100 bases:

>100_bases
GAATTTACGAGCTGAGAATATTGAACCAAAAATGTTTTTAGAACTCTTTAATTATTTGAATAAATCAAATAATGAATAAA
ATTAAGCTGTAGGTCAAATT

Downstream 100 bases:

>100_bases
AACACGTTATGCTCCATCACCAACTGGTTATTTACATATTGGTGGAGCGCGAACCGCTTTGTTTAATTATTTATTAGCTA
AAGCTTATGATGGTGATTTC

Product: hypothetical protein

Products: NA

Alternate protein names: CMK; 4-(cytidine-5'-diphospho)-2-C-methyl-D-erythritol kinase [H]

Number of amino acids: Translated: 265; Mature: 265

Protein sequence:

>265_residues
MKVKSFAKIDLGYSVYKKRKNITKHDFESIFILVESVYDDIEIIKIDKNVDDVHYYNETNEIYVYSRLVYKTLEWIRQTY
RIKNHYRINIKKRIPIGAGLGGGSSNAAVIMKSILELEGIKEINYKDVVNKLGADIPFFLSGYKTAYVSDCGSTLEDLSG
QFKLSYEVHLMNVNVNTKLVFEKFDDNQWHVIKNNFKTIIKNLKENIVTNIYNDLQEHCFELYPNIRYKYNELLREGFYT
ILSGAGSSFICIKLKDKENQVIHEN

Sequences:

>Translated_265_residues
MKVKSFAKIDLGYSVYKKRKNITKHDFESIFILVESVYDDIEIIKIDKNVDDVHYYNETNEIYVYSRLVYKTLE*IRQTY
RIKNHYRINIKKRIPIGAGLGGGSSNAAVIMKSILELEGIKEINYKDVVNKLGADIPFFLSGYKTAYVSDCGSTLEDLSG
QFKLSYEVHLMNVNVNTKLVFEKFDDNQ*HVIKNNFKTIIKNLKENIVTNIYNDLQEHCFELYPNIRYKYNELLREGFYT
ILSGAGSSFICIKLKDKENQVIHEN
>Mature_265_residues
MKVKSFAKIDLGYSVYKKRKNITKHDFESIFILVESVYDDIEIIKIDKNVDDVHYYNETNEIYVYSRLVYKTLE*IRQTY
RIKNHYRINIKKRIPIGAGLGGGSSNAAVIMKSILELEGIKEINYKDVVNKLGADIPFFLSGYKTAYVSDCGSTLEDLSG
QFKLSYEVHLMNVNVNTKLVFEKFDDNQ*HVIKNNFKTIIKNLKENIVTNIYNDLQEHCFELYPNIRYKYNELLREGFYT
ILSGAGSSFICIKLKDKENQVIHEN

Specific function: Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol [H]

COG id: COG1947

COG function: function code I; 4-diphosphocytidyl-2C-methyl-D-erythritol 2-phosphate synthase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the GHMP kinase family. IspE subfamily [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006204
- InterPro:   IPR004424
- InterPro:   IPR020568
- InterPro:   IPR014721 [H]

Pfam domain/function: PF00288 GHMP_kinases_N [H]

EC number: =2.7.1.148 [H]

Molecular weight: Translated: 30570; Mature: 30570

Theoretical pI: Translated: 8.63; Mature: 8.63

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKVKSFAKIDLGYSVYKKRKNITKHDFESIFILVESVYDDIEIIKIDKNVDDVHYYNETN
CCCCCCEEECCCHHHHHHHCCCCHHHHHHHHHHHHHHHCCEEEEEECCCCCCEEEECCCC
EIYVYSRLVYKTLEIRQTYRIKNHYRINIKKRIPIGAGLGGGSSNAAVIMKSILELEGIK
CEEEEHHHHHHHHHHHHHHEECCEEEEEEEEECCEECCCCCCCCCHHHHHHHHHHHCCCC
EINYKDVVNKLGADIPFFLSGYKTAYVSDCGSTLEDLSGQFKLSYEVHLMNVNVNTKLVF
CCCHHHHHHHHCCCCCHHHCCCCEEEHHHHHHHHHHCCCCEEEEEEEEEEEECCCEEEEE
EKFDDNQHVIKNNFKTIIKNLKENIVTNIYNDLQEHCFELYPNIRYKYNELLREGFYTIL
EECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHH
SGAGSSFICIKLKDKENQVIHEN
HCCCCEEEEEEEECCCCCCCCCC
>Mature Secondary Structure
MKVKSFAKIDLGYSVYKKRKNITKHDFESIFILVESVYDDIEIIKIDKNVDDVHYYNETN
CCCCCCEEECCCHHHHHHHCCCCHHHHHHHHHHHHHHHCCEEEEEECCCCCCEEEECCCC
EIYVYSRLVYKTLEIRQTYRIKNHYRINIKKRIPIGAGLGGGSSNAAVIMKSILELEGIK
CEEEEHHHHHHHHHHHHHHEECCEEEEEEEEECCEECCCCCCCCCHHHHHHHHHHHCCCC
EINYKDVVNKLGADIPFFLSGYKTAYVSDCGSTLEDLSGQFKLSYEVHLMNVNVNTKLVF
CCCHHHHHHHHCCCCCHHHCCCCEEEHHHHHHHHHHCCCCEEEEEEEEEEEECCCEEEEE
EKFDDNQHVIKNNFKTIIKNLKENIVTNIYNDLQEHCFELYPNIRYKYNELLREGFYTIL
EECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHH
SGAGSSFICIKLKDKENQVIHEN
HCCCCEEEEEEEECCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA