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The map label for this gene is allB [H]

Identifier: 209551931

GI number: 209551931

Start: 4529930

End: 4531309

Strand: Reverse

Name: allB [H]

Synonym: Rleg2_4364

Alternate gene names: 209551931

Gene position: 4531309-4529930 (Counterclockwise)

Preceding gene: 209551932

Following gene: 209551930

Centisome position: 99.85

GC content: 65.29

Gene sequence:

>1380_bases
ATGGACTTCGATCTCGTTCTGCAGGGCACGGTGGTGCTGCCGGACCGTATTCTCGAAGAAGGCTATGTTGCCGCCCGCGA
CGGCAGGATCGCCGAGGTTGGTCTCGGCGTGCCGCCCGCGGCGCGCGATCGGCATCTGCTCGGCAAAGCGCTGATCCTGC
CCGGCGCGATTGACGCGCAGGTACATTCGCTCTCGCAGAAGGACCAGGAGGATTTCATCTGGTCGACGCGTTCAGCGGCG
GCCGGCGGCGTAACAACGATCGTCGACATGCCCTATGACGAGGGCGACCTCGTCTGCTCGGCCGCAGCGGTCAAACGCAA
GATCGAGCATGCCGGCCAGCAGGCACGCGTCGACTTCGCGCTTTACGGCACCGTCGACCCGGAAGAAGGCCCGGCGCGGA
TCGGCGAGATGGTCGAGGCTGGGGTTGCCGCGTTCAAATTCTCGACCTTCGACACCGACCCCAAGCGTTTTCCACGCATT
CCGCCGGCCCTGCTCGACGCCTGTTTTGCGGCGATCGCGCCGACCGGGCTGACCGCAGGCGTGCACAATGAGGATGACGA
GGCGGTGCGCAGCTATATGGCTGAGGTGAAGGCAAGCGGCATCACCGACTGGCGGGCGCACGGCCTGTCACGGCCGCCGA
TTACCGAACTGCTGGCGATGCATACGATCTTCGAAACGGGTGCCGCGACCCACTGCCCCTCGCATGTGGTGCACTGCTCG
CTCGGGCGCGGCTATGACATCGCCCGCGCCTATCGCCGCGACGGCTTTGCGGCGACCGTCGAATGCTGCATCCATTATCT
GACGCTCGACGAGGAAAACGACGTCAAGCGCCTCGGCGGCAAGGCGAAGATCAATCCGCCGCTGCGGCCGCGCGCCGAGG
TGGAGACCCTCTGGCGGAAGGTGGCGGAGGGTGATGTCTGGCTGGTCTCGACCGATCACGTCAGCTGGTCGGAGAACCGC
AAGACCAATCCCGACATGCTCGCCAACGCCTCAGGCGTTCCAGGCCTCGAGGTGATGGTGCCGCTGTTCGTCAAAGGCGC
TATCGAGCGCGGTATTCCACTGACATGGGCGGCGAAGCTGATGGCGGAAAATCCGGCCAGGCATTTCCGGCTCGACCATA
TCAAGGGCGCGCTGACGCCGGGCAAAGATGCCGATATCACCGTGCTCGAACCGCGGGACAGCGTCTATGACGCTGCGGCC
AGCGGCAACAATGTCGTCGGCTGGAGCCCTTATAACGGTGTTCGCCTGCCCTGGACCGTTTCCGCCACCTATCTCAGGGG
CGAGAAGATCGCCGAAGGCGGCAAGGTGCTGGCCGAGCCCGGCAGCGGACGGTTCGTGCGGCCGTTGCCGCGCCAGGTCA
TTGCGGGAGCTCCTGCATGA

Upstream 100 bases:

>100_bases
CGACGATTTCTTTGCGCTCGGATCACTGGAGCATATCGAGGAGCGGCTGGCCCGCCACGAGGCGCAGGCCATCTGAACTC
GGCTTTTTGGAGGAGGCGTC

Downstream 100 bases:

>100_bases
GCCGCAATCTGCCCGTCAATGCCGGCCGGATCGCCGGAGATATCGAGGCGCTGGCCGCCATCACCGAGCCGGGGCACCCT
TGGACACGGCGGGCCTTCTC

Product: allantoinase

Products: NA

Alternate protein names: Allantoin-utilizing enzyme [H]

Number of amino acids: Translated: 459; Mature: 459

Protein sequence:

>459_residues
MDFDLVLQGTVVLPDRILEEGYVAARDGRIAEVGLGVPPAARDRHLLGKALILPGAIDAQVHSLSQKDQEDFIWSTRSAA
AGGVTTIVDMPYDEGDLVCSAAAVKRKIEHAGQQARVDFALYGTVDPEEGPARIGEMVEAGVAAFKFSTFDTDPKRFPRI
PPALLDACFAAIAPTGLTAGVHNEDDEAVRSYMAEVKASGITDWRAHGLSRPPITELLAMHTIFETGAATHCPSHVVHCS
LGRGYDIARAYRRDGFAATVECCIHYLTLDEENDVKRLGGKAKINPPLRPRAEVETLWRKVAEGDVWLVSTDHVSWSENR
KTNPDMLANASGVPGLEVMVPLFVKGAIERGIPLTWAAKLMAENPARHFRLDHIKGALTPGKDADITVLEPRDSVYDAAA
SGNNVVGWSPYNGVRLPWTVSATYLRGEKIAEGGKVLAEPGSGRFVRPLPRQVIAGAPA

Sequences:

>Translated_459_residues
MDFDLVLQGTVVLPDRILEEGYVAARDGRIAEVGLGVPPAARDRHLLGKALILPGAIDAQVHSLSQKDQEDFIWSTRSAA
AGGVTTIVDMPYDEGDLVCSAAAVKRKIEHAGQQARVDFALYGTVDPEEGPARIGEMVEAGVAAFKFSTFDTDPKRFPRI
PPALLDACFAAIAPTGLTAGVHNEDDEAVRSYMAEVKASGITDWRAHGLSRPPITELLAMHTIFETGAATHCPSHVVHCS
LGRGYDIARAYRRDGFAATVECCIHYLTLDEENDVKRLGGKAKINPPLRPRAEVETLWRKVAEGDVWLVSTDHVSWSENR
KTNPDMLANASGVPGLEVMVPLFVKGAIERGIPLTWAAKLMAENPARHFRLDHIKGALTPGKDADITVLEPRDSVYDAAA
SGNNVVGWSPYNGVRLPWTVSATYLRGEKIAEGGKVLAEPGSGRFVRPLPRQVIAGAPA
>Mature_459_residues
MDFDLVLQGTVVLPDRILEEGYVAARDGRIAEVGLGVPPAARDRHLLGKALILPGAIDAQVHSLSQKDQEDFIWSTRSAA
AGGVTTIVDMPYDEGDLVCSAAAVKRKIEHAGQQARVDFALYGTVDPEEGPARIGEMVEAGVAAFKFSTFDTDPKRFPRI
PPALLDACFAAIAPTGLTAGVHNEDDEAVRSYMAEVKASGITDWRAHGLSRPPITELLAMHTIFETGAATHCPSHVVHCS
LGRGYDIARAYRRDGFAATVECCIHYLTLDEENDVKRLGGKAKINPPLRPRAEVETLWRKVAEGDVWLVSTDHVSWSENR
KTNPDMLANASGVPGLEVMVPLFVKGAIERGIPLTWAAKLMAENPARHFRLDHIKGALTPGKDADITVLEPRDSVYDAAA
SGNNVVGWSPYNGVRLPWTVSATYLRGEKIAEGGKVLAEPGSGRFVRPLPRQVIAGAPA

Specific function: Catalyzes the conversion of allantoin (5- ureidohydantoin) to allantoic acid by hydrolytic cleavage of the five-member hydantoin ring [H]

COG id: COG0044

COG function: function code F; Dihydroorotase and related cyclic amidohydrolases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the DHOase family. Allantoinase subfamily [H]

Homologues:

Organism=Homo sapiens, GI4503375, Length=474, Percent_Identity=25.3164556962025, Blast_Score=100, Evalue=4e-21,
Organism=Homo sapiens, GI18105007, Length=421, Percent_Identity=26.3657957244656, Blast_Score=99, Evalue=6e-21,
Organism=Homo sapiens, GI19923821, Length=471, Percent_Identity=25.6900212314225, Blast_Score=98, Evalue=2e-20,
Organism=Homo sapiens, GI4503379, Length=462, Percent_Identity=23.8095238095238, Blast_Score=92, Evalue=8e-19,
Organism=Homo sapiens, GI190194363, Length=469, Percent_Identity=25.7995735607676, Blast_Score=91, Evalue=2e-18,
Organism=Homo sapiens, GI4503377, Length=468, Percent_Identity=23.7179487179487, Blast_Score=86, Evalue=9e-17,
Organism=Homo sapiens, GI4503051, Length=465, Percent_Identity=23.4408602150538, Blast_Score=83, Evalue=5e-16,
Organism=Homo sapiens, GI62422571, Length=459, Percent_Identity=23.3115468409586, Blast_Score=82, Evalue=9e-16,
Organism=Escherichia coli, GI87082175, Length=464, Percent_Identity=28.8793103448276, Blast_Score=155, Evalue=4e-39,
Organism=Escherichia coli, GI1786722, Length=458, Percent_Identity=27.5109170305677, Blast_Score=140, Evalue=2e-34,
Organism=Caenorhabditis elegans, GI193204318, Length=411, Percent_Identity=25.0608272506083, Blast_Score=96, Evalue=3e-20,
Organism=Caenorhabditis elegans, GI71989490, Length=464, Percent_Identity=23.9224137931034, Blast_Score=90, Evalue=3e-18,
Organism=Caenorhabditis elegans, GI17539558, Length=489, Percent_Identity=24.9488752556237, Blast_Score=87, Evalue=2e-17,
Organism=Saccharomyces cerevisiae, GI6322218, Length=389, Percent_Identity=27.7634961439589, Blast_Score=126, Evalue=7e-30,
Organism=Drosophila melanogaster, GI24642586, Length=415, Percent_Identity=27.4698795180723, Blast_Score=102, Evalue=6e-22,
Organism=Drosophila melanogaster, GI18859883, Length=441, Percent_Identity=26.3038548752834, Blast_Score=101, Evalue=8e-22,
Organism=Drosophila melanogaster, GI221377917, Length=476, Percent_Identity=26.4705882352941, Blast_Score=100, Evalue=3e-21,
Organism=Drosophila melanogaster, GI17137462, Length=463, Percent_Identity=24.8380129589633, Blast_Score=84, Evalue=1e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017593
- InterPro:   IPR006680
- InterPro:   IPR004722
- InterPro:   IPR002195
- InterPro:   IPR011059 [H]

Pfam domain/function: PF01979 Amidohydro_1 [H]

EC number: =3.5.2.5 [H]

Molecular weight: Translated: 49513; Mature: 49513

Theoretical pI: Translated: 6.07; Mature: 6.07

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDFDLVLQGTVVLPDRILEEGYVAARDGRIAEVGLGVPPAARDRHLLGKALILPGAIDAQ
CCCEEEEECEEECCHHHHHCCCEEECCCCEEEECCCCCCCCCCHHHHHHHEECCCCHHHH
VHSLSQKDQEDFIWSTRSAAAGGVTTIVDMPYDEGDLVCSAAAVKRKIEHAGQQARVDFA
HHHHHHCCCHHHHEECCCCCCCCEEEEEECCCCCCCEEEHHHHHHHHHHHCCCCEEEEEE
LYGTVDPEEGPARIGEMVEAGVAAFKFSTFDTDPKRFPRIPPALLDACFAAIAPTGLTAG
EEECCCCCCCHHHHHHHHHHHHHHEEEECCCCCHHHCCCCCHHHHHHHHHHHCCCCCCCC
VHNEDDEAVRSYMAEVKASGITDWRAHGLSRPPITELLAMHTIFETGAATHCPSHVVHCS
CCCCCHHHHHHHHHHHHHCCCCHHHHCCCCCCCHHHHHHHHHHHHCCCCCCCCCCEEEEE
LGRGYDIARAYRRDGFAATVECCIHYLTLDEENDVKRLGGKAKINPPLRPRAEVETLWRK
CCCCHHHHHHHHHCCCHHHHHHHHHHEECCCCCCHHHCCCCCCCCCCCCCCHHHHHHHHH
VAEGDVWLVSTDHVSWSENRKTNPDMLANASGVPGLEVMVPLFVKGAIERGIPLTWAAKL
HCCCCEEEEEECCCCCCCCCCCCHHHHCCCCCCCCHHHHHHHHHHHHHHCCCCHHHHHHH
MAENPARHFRLDHIKGALTPGKDADITVLEPRDSVYDAAASGNNVVGWSPYNGVRLPWTV
HHCCCHHHEEHHHHCCCCCCCCCCCEEEECCCCHHHHHHCCCCCEEEECCCCCEECEEEE
SATYLRGEKIAEGGKVLAEPGSGRFVRPLPRQVIAGAPA
EEEEECCCHHCCCCCEEECCCCCCEECCCCHHHHCCCCC
>Mature Secondary Structure
MDFDLVLQGTVVLPDRILEEGYVAARDGRIAEVGLGVPPAARDRHLLGKALILPGAIDAQ
CCCEEEEECEEECCHHHHHCCCEEECCCCEEEECCCCCCCCCCHHHHHHHEECCCCHHHH
VHSLSQKDQEDFIWSTRSAAAGGVTTIVDMPYDEGDLVCSAAAVKRKIEHAGQQARVDFA
HHHHHHCCCHHHHEECCCCCCCCEEEEEECCCCCCCEEEHHHHHHHHHHHCCCCEEEEEE
LYGTVDPEEGPARIGEMVEAGVAAFKFSTFDTDPKRFPRIPPALLDACFAAIAPTGLTAG
EEECCCCCCCHHHHHHHHHHHHHHEEEECCCCCHHHCCCCCHHHHHHHHHHHCCCCCCCC
VHNEDDEAVRSYMAEVKASGITDWRAHGLSRPPITELLAMHTIFETGAATHCPSHVVHCS
CCCCCHHHHHHHHHHHHHCCCCHHHHCCCCCCCHHHHHHHHHHHHCCCCCCCCCCEEEEE
LGRGYDIARAYRRDGFAATVECCIHYLTLDEENDVKRLGGKAKINPPLRPRAEVETLWRK
CCCCHHHHHHHHHCCCHHHHHHHHHHEECCCCCCHHHCCCCCCCCCCCCCCHHHHHHHHH
VAEGDVWLVSTDHVSWSENRKTNPDMLANASGVPGLEVMVPLFVKGAIERGIPLTWAAKL
HCCCCEEEEEECCCCCCCCCCCCHHHHCCCCCCCCHHHHHHHHHHHHHHCCCCHHHHHHH
MAENPARHFRLDHIKGALTPGKDADITVLEPRDSVYDAAASGNNVVGWSPYNGVRLPWTV
HHCCCHHHEEHHHHCCCCCCCCCCCEEEECCCCHHHHHHCCCCCEEEECCCCCEECEEEE
SATYLRGEKIAEGGKVLAEPGSGRFVRPLPRQVIAGAPA
EEEEECCCHHCCCCCEEECCCCCCEECCCCHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA