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The map label for this gene is cdd [H]

Identifier: 209551745

GI number: 209551745

Start: 4350520

End: 4350909

Strand: Direct

Name: cdd [H]

Synonym: Rleg2_4174

Alternate gene names: 209551745

Gene position: 4350520-4350909 (Clockwise)

Preceding gene: 209551744

Following gene: 209551746

Centisome position: 95.87

GC content: 60.51

Gene sequence:

>390_bases
ATGTCTCACGACCTGTTCGAAGCCGCTCGCGGCGCCATGGCTTTTGCCCATGCGCCCTATTCGAAATTTCCGGTCGGCGC
GGCGATTCGCGCCGAGGACGGCAAGGTCTATACCGGCGCCAACATCGAAAACCTGTCCTTTCCGCAAGGGTGGTGCGCCG
AGCCGACGGCGATCAGTGCCATGATCATGGGTGGCGCCAAGAAGATCGTCGAAATGGCGGTCATCGCCGAAAAGCTGCCG
CTCTGCCCGCCCTGCGGCGGTTGCCGCCAGAAGATCTCCGAATTCGCCTCCAAGGACACGAAGATCTATCTCTGCGATGA
GGCGGGCGTGCAGAAAACCATGACGATGGAAGAGCTCCTTCCCTTCAGCTTCGAGACCGAACTCGGATGA

Upstream 100 bases:

>100_bases
GCGCTGCCCTATATCCTCACCTGCATCCTGCTTGCCGGCTTCATCGGCGTTGCGACTCCGCCGAAGGCCGGCGGTGTGCC
CTATACGAAGGAGCGTTGAT

Downstream 100 bases:

>100_bases
AGGCGACGGTCGATCTGCTTGCCGCATTGCTCGGCGCCATCAAGCCGCGCCACGGCATCGTGCTCGGCTCCGGCCTCGGC
TCTCTCGTTGGTCAGCTGGA

Product: cytidine deaminase

Products: NA

Alternate protein names: CDA; Cytidine aminohydrolase [H]

Number of amino acids: Translated: 129; Mature: 128

Protein sequence:

>129_residues
MSHDLFEAARGAMAFAHAPYSKFPVGAAIRAEDGKVYTGANIENLSFPQGWCAEPTAISAMIMGGAKKIVEMAVIAEKLP
LCPPCGGCRQKISEFASKDTKIYLCDEAGVQKTMTMEELLPFSFETELG

Sequences:

>Translated_129_residues
MSHDLFEAARGAMAFAHAPYSKFPVGAAIRAEDGKVYTGANIENLSFPQGWCAEPTAISAMIMGGAKKIVEMAVIAEKLP
LCPPCGGCRQKISEFASKDTKIYLCDEAGVQKTMTMEELLPFSFETELG
>Mature_128_residues
SHDLFEAARGAMAFAHAPYSKFPVGAAIRAEDGKVYTGANIENLSFPQGWCAEPTAISAMIMGGAKKIVEMAVIAEKLPL
CPPCGGCRQKISEFASKDTKIYLCDEAGVQKTMTMEELLPFSFETELG

Specific function: This enzyme scavenge exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis [H]

COG id: COG0295

COG function: function code F; Cytidine deaminase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the cytidine and deoxycytidylate deaminase family [H]

Homologues:

Organism=Homo sapiens, GI11386157, Length=126, Percent_Identity=38.0952380952381, Blast_Score=90, Evalue=6e-19,
Organism=Caenorhabditis elegans, GI17540514, Length=125, Percent_Identity=40.8, Blast_Score=88, Evalue=1e-18,
Organism=Caenorhabditis elegans, GI17551074, Length=121, Percent_Identity=40.495867768595, Blast_Score=81, Evalue=1e-16,
Organism=Saccharomyces cerevisiae, GI6323274, Length=123, Percent_Identity=39.0243902439024, Blast_Score=84, Evalue=5e-18,
Organism=Drosophila melanogaster, GI24582744, Length=140, Percent_Identity=42.8571428571429, Blast_Score=89, Evalue=7e-19,
Organism=Drosophila melanogaster, GI19920920, Length=104, Percent_Identity=47.1153846153846, Blast_Score=86, Evalue=6e-18,
Organism=Drosophila melanogaster, GI24582741, Length=103, Percent_Identity=42.7184466019417, Blast_Score=78, Evalue=1e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016192
- InterPro:   IPR002125
- InterPro:   IPR006262
- InterPro:   IPR016193 [H]

Pfam domain/function: PF00383 dCMP_cyt_deam_1 [H]

EC number: =3.5.4.5 [H]

Molecular weight: Translated: 13883; Mature: 13752

Theoretical pI: Translated: 4.90; Mature: 4.90

Prosite motif: PS00903 CYT_DCMP_DEAMINASES

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.9 %Cys     (Translated Protein)
5.4 %Met     (Translated Protein)
9.3 %Cys+Met (Translated Protein)
3.9 %Cys     (Mature Protein)
4.7 %Met     (Mature Protein)
8.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSHDLFEAARGAMAFAHAPYSKFPVGAAIRAEDGKVYTGANIENLSFPQGWCAEPTAISA
CCCHHHHHHHHHHHHHCCCCCCCCCCEEEECCCCEEEECCCCCCCCCCCCCCCCCHHHHH
MIMGGAKKIVEMAVIAEKLPLCPPCGGCRQKISEFASKDTKIYLCDEAGVQKTMTMEELL
HHHCCHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHCCCCEEEEECCCCCCHHHHHHHHC
PFSFETELG
CCCCCCCCC
>Mature Secondary Structure 
SHDLFEAARGAMAFAHAPYSKFPVGAAIRAEDGKVYTGANIENLSFPQGWCAEPTAISA
CCHHHHHHHHHHHHHCCCCCCCCCCEEEECCCCEEEECCCCCCCCCCCCCCCCCHHHHH
MIMGGAKKIVEMAVIAEKLPLCPPCGGCRQKISEFASKDTKIYLCDEAGVQKTMTMEELL
HHHCCHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHCCCCEEEEECCCCCCHHHHHHHHC
PFSFETELG
CCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 2526291; 8969508; 9384377 [H]