Click here to switch to the map view.

The map label for this gene is gpmA [H]

Identifier: 209551697

GI number: 209551697

Start: 4305785

End: 4306420

Strand: Reverse

Name: gpmA [H]

Synonym: Rleg2_4126

Alternate gene names: 209551697

Gene position: 4306420-4305785 (Counterclockwise)

Preceding gene: 209551698

Following gene: 209551695

Centisome position: 94.9

GC content: 63.99

Gene sequence:

>636_bases
ATGAGCGGTACCCTCGTCCTCGTTCGCCACGGCCAGAGTGACTGGAACCTGAAGAATCTCTTCACCGGCTGGAAGGATCC
CGATCTGACGGCGCTCGGCATCGAGGAAGCCAATGCCGGCGGTAAGGCACTGGCCGAATACGGAATCAAATTCGACATCG
CCTATACCTCGGTGCTGGTGCGCGCGCAGCACACGCTGAAGCTCATCCTCGACAAGGTCGGCCAGCCCGATCTGCCGACG
ATCCGCGACCAGGCGCTGAACGAGCGCGACTATGGCGATCTCTCCGGCCTCAACAAGGACGACGCCCGCGCCAAATGGGG
CGAGGAACAGGTGCATATCTGGCGCCGCTCCTATGACGTCCCGCCGCCCGGCGGCGAAAGCCTGCGCGACACAGGCGCCC
GCGTCTGGCCCTATTACCTGACCGAAATCCTGCCGCGGGTGCTGCGCGGCGAGAAGGTGCTGGTTGCCGCACACGGCAAT
TCGCTGCGCTCGCTGGTCATGGTACTCGACAAGCTGACCAAGGAAGGCGTGCTCGCCCTCAATCTCGCGACCGGCGTGCC
GATGGTCTACAAGCTGAAGGCGGATTCCACCGTCGCCTCGAAGGAAGTGCTCGGCGACATGTCCGGCGCACACTGA

Upstream 100 bases:

>100_bases
CAAGGCAGCGCTCTGGGCGCGCGACAAGAAGCCGGGTCTCTATTCCATGCTCGACGTGCTCGGGCTTTCTTCCCAATAAC
GACATCTCGGAGGCATATTC

Downstream 100 bases:

>100_bases
ATGCAATCGCCTTCCCTGTTCCGACAGGGAAGGCTGTTCTCAAAGCGCGTCGCGTCAACTTGATTTATGCGACGCGCTTT
AGCTCTTTGTTTTACGCATG

Product: phosphoglyceromutase

Products: NA

Alternate protein names: BPG-dependent PGAM; PGAM; Phosphoglyceromutase; dPGM [H]

Number of amino acids: Translated: 211; Mature: 210

Protein sequence:

>211_residues
MSGTLVLVRHGQSDWNLKNLFTGWKDPDLTALGIEEANAGGKALAEYGIKFDIAYTSVLVRAQHTLKLILDKVGQPDLPT
IRDQALNERDYGDLSGLNKDDARAKWGEEQVHIWRRSYDVPPPGGESLRDTGARVWPYYLTEILPRVLRGEKVLVAAHGN
SLRSLVMVLDKLTKEGVLALNLATGVPMVYKLKADSTVASKEVLGDMSGAH

Sequences:

>Translated_211_residues
MSGTLVLVRHGQSDWNLKNLFTGWKDPDLTALGIEEANAGGKALAEYGIKFDIAYTSVLVRAQHTLKLILDKVGQPDLPT
IRDQALNERDYGDLSGLNKDDARAKWGEEQVHIWRRSYDVPPPGGESLRDTGARVWPYYLTEILPRVLRGEKVLVAAHGN
SLRSLVMVLDKLTKEGVLALNLATGVPMVYKLKADSTVASKEVLGDMSGAH
>Mature_210_residues
SGTLVLVRHGQSDWNLKNLFTGWKDPDLTALGIEEANAGGKALAEYGIKFDIAYTSVLVRAQHTLKLILDKVGQPDLPTI
RDQALNERDYGDLSGLNKDDARAKWGEEQVHIWRRSYDVPPPGGESLRDTGARVWPYYLTEILPRVLRGEKVLVAAHGNS
LRSLVMVLDKLTKEGVLALNLATGVPMVYKLKADSTVASKEVLGDMSGAH

Specific function: Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate [H]

COG id: COG0588

COG function: function code G; Phosphoglycerate mutase 1

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the phosphoglycerate mutase family. BPG- dependent PGAM subfamily [H]

Homologues:

Organism=Homo sapiens, GI4505753, Length=230, Percent_Identity=46.9565217391304, Blast_Score=195, Evalue=2e-50,
Organism=Homo sapiens, GI50593010, Length=230, Percent_Identity=45.2173913043478, Blast_Score=195, Evalue=3e-50,
Organism=Homo sapiens, GI71274132, Length=230, Percent_Identity=44.3478260869565, Blast_Score=181, Evalue=3e-46,
Organism=Homo sapiens, GI4502445, Length=235, Percent_Identity=37.8723404255319, Blast_Score=161, Evalue=3e-40,
Organism=Homo sapiens, GI40353764, Length=235, Percent_Identity=37.8723404255319, Blast_Score=161, Evalue=3e-40,
Organism=Homo sapiens, GI310129614, Length=160, Percent_Identity=48.75, Blast_Score=134, Evalue=8e-32,
Organism=Escherichia coli, GI1786970, Length=227, Percent_Identity=46.6960352422907, Blast_Score=190, Evalue=5e-50,
Organism=Saccharomyces cerevisiae, GI6322697, Length=213, Percent_Identity=41.7840375586854, Blast_Score=153, Evalue=2e-38,
Organism=Saccharomyces cerevisiae, GI6324516, Length=265, Percent_Identity=24.9056603773585, Blast_Score=92, Evalue=7e-20,
Organism=Saccharomyces cerevisiae, GI6320183, Length=270, Percent_Identity=24.4444444444444, Blast_Score=86, Evalue=3e-18,
Organism=Saccharomyces cerevisiae, GI6324857, Length=186, Percent_Identity=27.9569892473118, Blast_Score=66, Evalue=4e-12,
Organism=Drosophila melanogaster, GI85725270, Length=231, Percent_Identity=45.021645021645, Blast_Score=190, Evalue=7e-49,
Organism=Drosophila melanogaster, GI85725272, Length=231, Percent_Identity=45.021645021645, Blast_Score=190, Evalue=7e-49,
Organism=Drosophila melanogaster, GI24650981, Length=231, Percent_Identity=45.021645021645, Blast_Score=190, Evalue=7e-49,
Organism=Drosophila melanogaster, GI24646216, Length=231, Percent_Identity=42.8571428571429, Blast_Score=185, Evalue=2e-47,
Organism=Drosophila melanogaster, GI28571817, Length=235, Percent_Identity=35.3191489361702, Blast_Score=136, Evalue=9e-33,
Organism=Drosophila melanogaster, GI28571815, Length=235, Percent_Identity=35.3191489361702, Blast_Score=136, Evalue=9e-33,
Organism=Drosophila melanogaster, GI24648979, Length=235, Percent_Identity=35.3191489361702, Blast_Score=136, Evalue=1e-32,

Paralogues:

None

Copy number: 960 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 40 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013078
- InterPro:   IPR001345
- InterPro:   IPR005952 [H]

Pfam domain/function: PF00300 PGAM [H]

EC number: =5.4.2.1 [H]

Molecular weight: Translated: 23189; Mature: 23058

Theoretical pI: Translated: 7.09; Mature: 7.09

Prosite motif: PS00175 PG_MUTASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
1.9 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
1.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSGTLVLVRHGQSDWNLKNLFTGWKDPDLTALGIEEANAGGKALAEYGIKFDIAYTSVLV
CCCEEEEEECCCCCCCHHHHHCCCCCCCEEEECCCCCCCCHHHHHHCCCEEEHHHHHHHH
RAQHTLKLILDKVGQPDLPTIRDQALNERDYGDLSGLNKDDARAKWGEEQVHIWRRSYDV
HHHHHHHHHHHHCCCCCCCCHHHHHCCCCCCCCCCCCCCCHHHHHCCHHHHHHHHHHCCC
PPPGGESLRDTGARVWPYYLTEILPRVLRGEKVLVAAHGNSLRSLVMVLDKLTKEGVLAL
CCCCCCCHHHCCCEEHHHHHHHHHHHHHCCCEEEEEECCCHHHHHHHHHHHHHHCCEEEE
NLATGVPMVYKLKADSTVASKEVLGDMSGAH
EECCCCCEEEEEECCCCHHHHHHHHHCCCCC
>Mature Secondary Structure 
SGTLVLVRHGQSDWNLKNLFTGWKDPDLTALGIEEANAGGKALAEYGIKFDIAYTSVLV
CCEEEEEECCCCCCCHHHHHCCCCCCCEEEECCCCCCCCHHHHHHCCCEEEHHHHHHHH
RAQHTLKLILDKVGQPDLPTIRDQALNERDYGDLSGLNKDDARAKWGEEQVHIWRRSYDV
HHHHHHHHHHHHCCCCCCCCHHHHHCCCCCCCCCCCCCCCHHHHHCCHHHHHHHHHHCCC
PPPGGESLRDTGARVWPYYLTEILPRVLRGEKVLVAAHGNSLRSLVMVLDKLTKEGVLAL
CCCCCCCHHHCCCEEHHHHHHHHHHHHHCCCEEEEEECCCHHHHHHHHHHHHHHCCEEEE
NLATGVPMVYKLKADSTVASKEVLGDMSGAH
EECCCCCEEEEEECCCCHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA