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The map label for this gene is dapB [H]

Identifier: 209551698

GI number: 209551698

Start: 4306442

End: 4307266

Strand: Reverse

Name: dapB [H]

Synonym: Rleg2_4127

Alternate gene names: 209551698

Gene position: 4307266-4306442 (Counterclockwise)

Preceding gene: 209551699

Following gene: 209551697

Centisome position: 94.92

GC content: 67.52

Gene sequence:

>825_bases
ATGAGCGATGCTGCGATGAAACTGGTGGTGGTTGGCGCAGCCGGGCGCATGGGGCAGACGCTGATCCGGCTCATCCATTC
CATCGAGGGCGCGACGCTGCATGCGGCGGTCGAGCGCAGCGGCTCGCCCTTTATCGGCAAGGATGCCGGCGAGATTGCCG
GTCTCGGCCCGAGCGGCATCCTCATCGGCGACGATCCGCTCAATGCCTTTCTGCATGCCGAAGGCGTGCTCGACTTCACC
TCGCCGGCCGCGACAGCGGAATTTTCGGGGCTGGCGGCGCAGGCCCGCATCGTCCATGTCGTCGGCACGACCGGCTGTTC
GGCCGACGACGACGCCAGGATCGCCGCGGCAGCCCGTCATGCCCGCGTGGTCAAGTCAGGCAATATGAGCCTCGGGGTCA
ATCTGCTCAGCGTGCTCGCCGAGCAGGCCGCCCGCGCGCTCGAGCCTGAGGACTGGGATATCGAAATCCTGGAAATGCAC
CACAAGCACAAGGTGGACGCGCCTTCCGGCACCGCCCTCCTCCTCGGCGAGGCCGCGGCCAAGGGGCGCGGCATCGATCT
CGCCTCGAAATCGGTCCGGGTGCGCGACGGCCATACCGGCGCCCGCGAGGCGGGCACGATCGGTTTTGCGACGCTGCGCG
GCGGCTCCGTCATCGGCGAGCATTCGGTGCTTTTCGCCGGCGAAGGCGAGATCGTCACCCTGTCGCACAGCGCCGCCGAC
CGGTCGATCTTTGCGCGCGGCGCCATCAAGGCAGCGCTCTGGGCGCGCGACAAGAAGCCGGGTCTCTATTCCATGCTCGA
CGTGCTCGGGCTTTCTTCCCAATAA

Upstream 100 bases:

>100_bases
TCACGAGACGCTTGCGAAGGTCAGCGACGGTCTTTACGCTCGCCTCAACAATCTGCAGAGGCCTTCGGCCTCCGATTCAA
ACTGACCTGGTGAGACTGAC

Downstream 100 bases:

>100_bases
CGACATCTCGGAGGCATATTCATGAGCGGTACCCTCGTCCTCGTTCGCCACGGCCAGAGTGACTGGAACCTGAAGAATCT
CTTCACCGGCTGGAAGGATC

Product: dihydrodipicolinate reductase

Products: NA

Alternate protein names: DHPR [H]

Number of amino acids: Translated: 274; Mature: 273

Protein sequence:

>274_residues
MSDAAMKLVVVGAAGRMGQTLIRLIHSIEGATLHAAVERSGSPFIGKDAGEIAGLGPSGILIGDDPLNAFLHAEGVLDFT
SPAATAEFSGLAAQARIVHVVGTTGCSADDDARIAAAARHARVVKSGNMSLGVNLLSVLAEQAARALEPEDWDIEILEMH
HKHKVDAPSGTALLLGEAAAKGRGIDLASKSVRVRDGHTGAREAGTIGFATLRGGSVIGEHSVLFAGEGEIVTLSHSAAD
RSIFARGAIKAALWARDKKPGLYSMLDVLGLSSQ

Sequences:

>Translated_274_residues
MSDAAMKLVVVGAAGRMGQTLIRLIHSIEGATLHAAVERSGSPFIGKDAGEIAGLGPSGILIGDDPLNAFLHAEGVLDFT
SPAATAEFSGLAAQARIVHVVGTTGCSADDDARIAAAARHARVVKSGNMSLGVNLLSVLAEQAARALEPEDWDIEILEMH
HKHKVDAPSGTALLLGEAAAKGRGIDLASKSVRVRDGHTGAREAGTIGFATLRGGSVIGEHSVLFAGEGEIVTLSHSAAD
RSIFARGAIKAALWARDKKPGLYSMLDVLGLSSQ
>Mature_273_residues
SDAAMKLVVVGAAGRMGQTLIRLIHSIEGATLHAAVERSGSPFIGKDAGEIAGLGPSGILIGDDPLNAFLHAEGVLDFTS
PAATAEFSGLAAQARIVHVVGTTGCSADDDARIAAAARHARVVKSGNMSLGVNLLSVLAEQAARALEPEDWDIEILEMHH
KHKVDAPSGTALLLGEAAAKGRGIDLASKSVRVRDGHTGAREAGTIGFATLRGGSVIGEHSVLFAGEGEIVTLSHSAADR
SIFARGAIKAALWARDKKPGLYSMLDVLGLSSQ

Specific function: Biosynthesis of diaminopimelate and lysine from aspartate semialdehyde; second step. [C]

COG id: COG0289

COG function: function code E; Dihydrodipicolinate reductase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the dihydrodipicolinate reductase family [H]

Homologues:

Organism=Escherichia coli, GI1786214, Length=279, Percent_Identity=43.010752688172, Blast_Score=204, Evalue=6e-54,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR022663
- InterPro:   IPR000846
- InterPro:   IPR022664
- InterPro:   IPR011770
- InterPro:   IPR016040 [H]

Pfam domain/function: PF05173 DapB_C; PF01113 DapB_N [H]

EC number: =1.3.1.26 [H]

Molecular weight: Translated: 28161; Mature: 28030

Theoretical pI: Translated: 6.59; Mature: 6.59

Prosite motif: PS01298 DAPB

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSDAAMKLVVVGAAGRMGQTLIRLIHSIEGATLHAAVERSGSPFIGKDAGEIAGLGPSGI
CCCCEEEEEEEECCCHHHHHHHHHHHHCCCCEEEEEHHCCCCCCCCCCCCHHCCCCCCCE
LIGDDPLNAFLHAEGVLDFTSPAATAEFSGLAAQARIVHVVGTTGCSADDDARIAAAARH
EEECCCCCHHEEECCCEECCCCCCHHHHCCCEEEEEEEEEEECCCCCCCCCHHHHHHHHH
ARVVKSGNMSLGVNLLSVLAEQAARALEPEDWDIEILEMHHKHKVDAPSGTALLLGEAAA
HHHHCCCCCEEHHHHHHHHHHHHHHHCCCCCCCCCEEEEHHHCCCCCCCCCEEEEECCCC
KGRGIDLASKSVRVRDGHTGAREAGTIGFATLRGGSVIGEHSVLFAGEGEIVTLSHSAAD
CCCCCEECCCEEEEECCCCCCCCCCCEEEEEECCCCEECCCEEEEECCCCEEEEECCCCC
RSIFARGAIKAALWARDKKPGLYSMLDVLGLSSQ
HHHHHHHHHHHHHHCCCCCCCHHHHHHHHCCCCC
>Mature Secondary Structure 
SDAAMKLVVVGAAGRMGQTLIRLIHSIEGATLHAAVERSGSPFIGKDAGEIAGLGPSGI
CCCEEEEEEEECCCHHHHHHHHHHHHCCCCEEEEEHHCCCCCCCCCCCCHHCCCCCCCE
LIGDDPLNAFLHAEGVLDFTSPAATAEFSGLAAQARIVHVVGTTGCSADDDARIAAAARH
EEECCCCCHHEEECCCEECCCCCCHHHHCCCEEEEEEEEEEECCCCCCCCCHHHHHHHHH
ARVVKSGNMSLGVNLLSVLAEQAARALEPEDWDIEILEMHHKHKVDAPSGTALLLGEAAA
HHHHCCCCCEEHHHHHHHHHHHHHHHCCCCCCCCCEEEEHHHCCCCCCCCCEEEEECCCC
KGRGIDLASKSVRVRDGHTGAREAGTIGFATLRGGSVIGEHSVLFAGEGEIVTLSHSAAD
CCCCCEECCCEEEEECCCCCCCCCCCEEEEEECCCCEECCCEEEEECCCCEEEEECCCCC
RSIFARGAIKAALWARDKKPGLYSMLDVLGLSSQ
HHHHHHHHHHHHHHCCCCCCCHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA