Click here to switch to the map view.

The map label for this gene is kdsB [H]

Identifier: 209551655

GI number: 209551655

Start: 4258623

End: 4259378

Strand: Reverse

Name: kdsB [H]

Synonym: Rleg2_4084

Alternate gene names: 209551655

Gene position: 4259378-4258623 (Counterclockwise)

Preceding gene: 209551657

Following gene: 209551654

Centisome position: 93.86

GC content: 63.1

Gene sequence:

>756_bases
ATGAGTGATTCAAATTTAGACGGCGTGCTCGTACTGATCCCGGCGCGGATGGCCTCCACCCGGCTTCCGGGCAAGCCGCT
CGCCGATATTTGCGGGCTGCCGATGATCGTCCAGGTGGCGATGCGCGCCCAAGAGGCAGCCATCGGCCGCGTCGTCGTCG
CCGTCGACGACATCAGGGTGTTCGATGCGGTTTCTGCCGCCGGCTTCGAAGTCGTCATGACCAGCAGCGATCATCAATCG
GGTTCCGATCGGATCTTCGAGGCGCTGCAGAAAGTCGATCCTGCCGGCAAGGCGGAATTCATCGTCAACGTCCAGGGCGA
TCTGCCGACGATCGATCCGGAAACCGTGCGCGCGGCTTTGCGCCCTCTCGAGAACGAGGCGGTCGATATCGGCACGCTGA
CGACCGAAATCGATAATGAAGAGGACAAAACCGCGCCGCACATCGTCAAGGTCGTCGGCTCGCCCGTGTCCGACACCCGA
CTGCGCGGGCTCTATTTCACGCGTGCGACCGCACCTTACGGCAAAGGTCCGCTCTACCACCATATCGGCCTTTACGCCTA
TCGGCGCGCGGCGCTTGAACGGTTCGTCTCACTCGGGCCTTCGACGCTCGAAAGGCGCGAAGCGCTGGAGCAGCTGCGGG
CGCTGGAGGCAGGCATGCGCATCGACGCCGAGATCGTTGACACGGTTCCGCTCGGTGTCGATACTCCCGCCGACCTCGAA
AAAGCGCGGCGCATCCTCTCCGCCAGAACAGGATGA

Upstream 100 bases:

>100_bases
CGCGGAACCTATGTCTTTTGGCTGATCGTTGCAACTGTCTAAATGGTCTTGTGCGTGAGACTTTTTGACACTTTTCAGCC
CGGAATAGAAGGCCCGACCA

Downstream 100 bases:

>100_bases
TTTTAGGCTCGGTTGGCCTAAAATCTGAATCCTGTTCTCAATTAAAGAGTTAGAGCATGATGTCGTCCGAAAACCGCTCA
CACTTTTCGGCATCATGCTC

Product: 3-deoxy-manno-octulosonate cytidylyltransferase

Products: NA

Alternate protein names: CMP-2-keto-3-deoxyoctulosonic acid synthase; CKS; CMP-KDO synthase [H]

Number of amino acids: Translated: 251; Mature: 250

Protein sequence:

>251_residues
MSDSNLDGVLVLIPARMASTRLPGKPLADICGLPMIVQVAMRAQEAAIGRVVVAVDDIRVFDAVSAAGFEVVMTSSDHQS
GSDRIFEALQKVDPAGKAEFIVNVQGDLPTIDPETVRAALRPLENEAVDIGTLTTEIDNEEDKTAPHIVKVVGSPVSDTR
LRGLYFTRATAPYGKGPLYHHIGLYAYRRAALERFVSLGPSTLERREALEQLRALEAGMRIDAEIVDTVPLGVDTPADLE
KARRILSARTG

Sequences:

>Translated_251_residues
MSDSNLDGVLVLIPARMASTRLPGKPLADICGLPMIVQVAMRAQEAAIGRVVVAVDDIRVFDAVSAAGFEVVMTSSDHQS
GSDRIFEALQKVDPAGKAEFIVNVQGDLPTIDPETVRAALRPLENEAVDIGTLTTEIDNEEDKTAPHIVKVVGSPVSDTR
LRGLYFTRATAPYGKGPLYHHIGLYAYRRAALERFVSLGPSTLERREALEQLRALEAGMRIDAEIVDTVPLGVDTPADLE
KARRILSARTG
>Mature_250_residues
SDSNLDGVLVLIPARMASTRLPGKPLADICGLPMIVQVAMRAQEAAIGRVVVAVDDIRVFDAVSAAGFEVVMTSSDHQSG
SDRIFEALQKVDPAGKAEFIVNVQGDLPTIDPETVRAALRPLENEAVDIGTLTTEIDNEEDKTAPHIVKVVGSPVSDTRL
RGLYFTRATAPYGKGPLYHHIGLYAYRRAALERFVSLGPSTLERREALEQLRALEAGMRIDAEIVDTVPLGVDTPADLEK
ARRILSARTG

Specific function: Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria [H]

COG id: COG1212

COG function: function code M; CMP-2-keto-3-deoxyoctulosonic acid synthetase

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the kdsB family [H]

Homologues:

Organism=Escherichia coli, GI1787147, Length=246, Percent_Identity=44.3089430894309, Blast_Score=177, Evalue=6e-46,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003329
- InterPro:   IPR004528 [H]

Pfam domain/function: PF02348 CTP_transf_3 [H]

EC number: =2.7.7.38 [H]

Molecular weight: Translated: 27096; Mature: 26965

Theoretical pI: Translated: 4.90; Mature: 4.90

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSDSNLDGVLVLIPARMASTRLPGKPLADICGLPMIVQVAMRAQEAAIGRVVVAVDDIRV
CCCCCCCEEEEEECCHHHHCCCCCCCHHHHHCCHHHHHHHHHHHHHHHCEEEEEECCHHH
FDAVSAAGFEVVMTSSDHQSGSDRIFEALQKVDPAGKAEFIVNVQGDLPTIDPETVRAAL
HHHHHHCCEEEEEECCCCCCCHHHHHHHHHHCCCCCCEEEEEEECCCCCCCCHHHHHHHH
RPLENEAVDIGTLTTEIDNEEDKTAPHIVKVVGSPVSDTRLRGLYFTRATAPYGKGPLYH
CCCCCCCEEEEEEEECCCCCCCCCHHHHHHHHCCCCCCHHHCEEEEEECCCCCCCCCHHH
HIGLYAYRRAALERFVSLGPSTLERREALEQLRALEAGMRIDAEIVDTVPLGVDTPADLE
HHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCCCHHHHHEECCCCCCCHHHH
KARRILSARTG
HHHHHHHCCCC
>Mature Secondary Structure 
SDSNLDGVLVLIPARMASTRLPGKPLADICGLPMIVQVAMRAQEAAIGRVVVAVDDIRV
CCCCCCEEEEEECCHHHHCCCCCCCHHHHHCCHHHHHHHHHHHHHHHCEEEEEECCHHH
FDAVSAAGFEVVMTSSDHQSGSDRIFEALQKVDPAGKAEFIVNVQGDLPTIDPETVRAAL
HHHHHHCCEEEEEECCCCCCCHHHHHHHHHHCCCCCCEEEEEEECCCCCCCCHHHHHHHH
RPLENEAVDIGTLTTEIDNEEDKTAPHIVKVVGSPVSDTRLRGLYFTRATAPYGKGPLYH
CCCCCCCEEEEEEEECCCCCCCCCHHHHHHHHCCCCCCHHHCEEEEEECCCCCCCCCHHH
HIGLYAYRRAALERFVSLGPSTLERREALEQLRALEAGMRIDAEIVDTVPLGVDTPADLE
HHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCCCHHHHHEECCCCCCCHHHH
KARRILSARTG
HHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA