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The map label for this gene is pheA [H]

Identifier: 209551654

GI number: 209551654

Start: 4257645

End: 4258499

Strand: Reverse

Name: pheA [H]

Synonym: Rleg2_4083

Alternate gene names: 209551654

Gene position: 4258499-4257645 (Counterclockwise)

Preceding gene: 209551655

Following gene: 209551648

Centisome position: 93.84

GC content: 60.7

Gene sequence:

>855_bases
ATGAACATCAAGACCAACAGGATCGCCTTCCAGGGCGAATTCGGCGCCAATTCCGACATGGCCAGCCGCGACATGTTTCC
GACCATGGAGCCGCTGCCCTGCCAGACCTTCGAGGATGCGTTTACGGCGGTCGACAACGGCGACGCCGATATCGGGATGA
TCCCGATCGAGAACACGATCGCCGGGCGCGTCGCCGATATCCACCATCTGCTGCCGGAATCGCGGCTGCACATCATCGGC
GAATATTTCATGCCGATCCGCTTCCAGCTGATGGTGCTGCCGGGGGTGACCAAGGACGAGATCCGCACGGTGCACAGCCA
TATCCACGCGCTCGGCCAGTGCCGCAAGATCGTCCGCGCCAACGGCTGGAAACCTATCATCGCCGGCGATACCGCCGGTG
CGGCAAAACTGGTGAAAGAGACCGGCGATCGGTCGATGGCCGCCTTGGCGCCCCGCCTTGCCGCCGATCTCTACGGGCTC
GAGATCATCGCCGAAAATGTCGAGGATACCGAAAACAACGTCACCCGTTTCGTCGTGCTGTCGCGCGATGAGGAATGGGC
GCAACGGAATTCGGCGGATGAAAAGGTCGTCACCACCTTCGTCTTCAACGTCCGCAACATTCCGGCCGCGCTCTACAAGG
CGCTCGGCGGGTTCGCCACCAACAACATCAACATGACGAAGCTGGAAAGCTATCAGCTCGGCGGGAGATTTGTGGCGACG
CAGTTCTACGCCGATATCGAAGGCCATCCGAACGATCCGAACGTGCGCCGGGCATTGGAAGAATTGCGGTTCTTCTCCGA
GAAGGTGCGCATCCTCGGCGTCTACAAGGGGCATGCGATGCGAGGCCTGCTTTAG

Upstream 100 bases:

>100_bases
TCTGAATCCTGTTCTCAATTAAAGAGTTAGAGCATGATGTCGTCCGAAAACCGCTCACACTTTTCGGCATCATGCTCTAA
GTCGAACTGACGGAACCATC

Downstream 100 bases:

>100_bases
CTCTTAGTTCTATGCATATGCCCGGAAGCGCTGCACACTTCCGGGCATATGCACGAGGGGCCTCGACATCGGCTATTATT
TATCCGGCTCGCAGACGCGC

Product: prephenate dehydratase

Products: NA

Alternate protein names: Chorismate mutase; CM; Prephenate dehydratase; PDT [H]

Number of amino acids: Translated: 284; Mature: 284

Protein sequence:

>284_residues
MNIKTNRIAFQGEFGANSDMASRDMFPTMEPLPCQTFEDAFTAVDNGDADIGMIPIENTIAGRVADIHHLLPESRLHIIG
EYFMPIRFQLMVLPGVTKDEIRTVHSHIHALGQCRKIVRANGWKPIIAGDTAGAAKLVKETGDRSMAALAPRLAADLYGL
EIIAENVEDTENNVTRFVVLSRDEEWAQRNSADEKVVTTFVFNVRNIPAALYKALGGFATNNINMTKLESYQLGGRFVAT
QFYADIEGHPNDPNVRRALEELRFFSEKVRILGVYKGHAMRGLL

Sequences:

>Translated_284_residues
MNIKTNRIAFQGEFGANSDMASRDMFPTMEPLPCQTFEDAFTAVDNGDADIGMIPIENTIAGRVADIHHLLPESRLHIIG
EYFMPIRFQLMVLPGVTKDEIRTVHSHIHALGQCRKIVRANGWKPIIAGDTAGAAKLVKETGDRSMAALAPRLAADLYGL
EIIAENVEDTENNVTRFVVLSRDEEWAQRNSADEKVVTTFVFNVRNIPAALYKALGGFATNNINMTKLESYQLGGRFVAT
QFYADIEGHPNDPNVRRALEELRFFSEKVRILGVYKGHAMRGLL
>Mature_284_residues
MNIKTNRIAFQGEFGANSDMASRDMFPTMEPLPCQTFEDAFTAVDNGDADIGMIPIENTIAGRVADIHHLLPESRLHIIG
EYFMPIRFQLMVLPGVTKDEIRTVHSHIHALGQCRKIVRANGWKPIIAGDTAGAAKLVKETGDRSMAALAPRLAADLYGL
EIIAENVEDTENNVTRFVVLSRDEEWAQRNSADEKVVTTFVFNVRNIPAALYKALGGFATNNINMTKLESYQLGGRFVAT
QFYADIEGHPNDPNVRRALEELRFFSEKVRILGVYKGHAMRGLL

Specific function: L-phenylalanine biosynthesis. [C]

COG id: COG0077

COG function: function code E; Prephenate dehydratase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 prephenate dehydratase domain [H]

Homologues:

Organism=Escherichia coli, GI1788951, Length=281, Percent_Identity=32.0284697508897, Blast_Score=131, Evalue=4e-32,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008242
- InterPro:   IPR002701
- InterPro:   IPR020822
- InterPro:   IPR010952
- InterPro:   IPR001086
- InterPro:   IPR018528 [H]

Pfam domain/function: PF01817 CM_2; PF00800 PDT [H]

EC number: =5.4.99.5; =4.2.1.51 [H]

Molecular weight: Translated: 31634; Mature: 31634

Theoretical pI: Translated: 6.31; Mature: 6.31

Prosite motif: PS00857 PREPHENATE_DEHYDR_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNIKTNRIAFQGEFGANSDMASRDMFPTMEPLPCQTFEDAFTAVDNGDADIGMIPIENTI
CCCCCCEEEEEECCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHCCCCCCCEEEEECCCHH
AGRVADIHHLLPESRLHIIGEYFMPIRFQLMVLPGVTKDEIRTVHSHIHALGQCRKIVRA
HHHHHHHHHHCCHHHHHHHHHHHCCEEEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHC
NGWKPIIAGDTAGAAKLVKETGDRSMAALAPRLAADLYGLEIIAENVEDTENNVTRFVVL
CCCCEEEECCCCHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEEE
SRDEEWAQRNSADEKVVTTFVFNVRNIPAALYKALGGFATNNINMTKLESYQLGGRFVAT
ECCHHHHHCCCCCHHHHHHHHHHHHCCHHHHHHHHCCCCCCCCCEEEECCCCCCCEEEEE
QFYADIEGHPNDPNVRRALEELRFFSEKVRILGVYKGHAMRGLL
EEEEECCCCCCCCHHHHHHHHHHHHHHHEEEEEEECCCHHHCCC
>Mature Secondary Structure
MNIKTNRIAFQGEFGANSDMASRDMFPTMEPLPCQTFEDAFTAVDNGDADIGMIPIENTI
CCCCCCEEEEEECCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHCCCCCCCEEEEECCCHH
AGRVADIHHLLPESRLHIIGEYFMPIRFQLMVLPGVTKDEIRTVHSHIHALGQCRKIVRA
HHHHHHHHHHCCHHHHHHHHHHHCCEEEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHC
NGWKPIIAGDTAGAAKLVKETGDRSMAALAPRLAADLYGLEIIAENVEDTENNVTRFVVL
CCCCEEEECCCCHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEEE
SRDEEWAQRNSADEKVVTTFVFNVRNIPAALYKALGGFATNNINMTKLESYQLGGRFVAT
ECCHHHHHCCCCCHHHHHHHHHHHHCCHHHHHHHHCCCCCCCCCEEEECCCCCCCEEEEE
QFYADIEGHPNDPNVRRALEELRFFSEKVRILGVYKGHAMRGLL
EEEEECCCCCCCCHHHHHHHHHHHHHHHEEEEEEECCCHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]