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The map label for this gene is catD [H]

Identifier: 209551635

GI number: 209551635

Start: 4238768

End: 4239619

Strand: Reverse

Name: catD [H]

Synonym: Rleg2_4064

Alternate gene names: 209551635

Gene position: 4239619-4238768 (Counterclockwise)

Preceding gene: 209551636

Following gene: 209551634

Centisome position: 93.43

GC content: 60.45

Gene sequence:

>852_bases
ATGCGCGCAACCGCGATCGGCATGCTGACGTTGTTTTCGATGTTTCTCACCGTTACCGGCGCTCAATCCGGCGAGCGCTG
GGCAGAGCTTCCGGCTTTTCCGGCGATGCCCGTGCCGAAGACCAGCGGCATGGCTGAAGTGAACGACATCAAGATGTATT
ACGCCGAATATGGTGAAGGCGAGCCGATGCTCTTCATCCATGGCGGGCTTGGCAATGCCGATGTCTGGGGTCACCAGATC
GCCGAATTCTCCAAAGACCACCTGGTCATCGTTGCCGACAGCCGCGGGCATGGACGCTCGACGCGCAGCCAAAAGCCCTT
CGGCTACGACCTGATGACATCGGATTATGCAGCCCTTCTCGACCATCTGAAGATCGGCAAGGTGACGCTGGTGGGATGGT
CTAACGGCGGCATCATCGGCATCGACATGGCGATGAACCATCCGGAAAAGCTGACGCGCGTCATTGCCCAGGCGGCCAAT
GTGACCACGGACGGCGTCAAGCCCGACGTCTTGAGCAACAAGACCTTCAACGACTATATCAACGTCGCCGGCGAACAATA
CCGGAAGCTGTCGCCGACGCCGAACGAGTACGACGCCTTCGTCACCCAGATCTCCGAGATGTGGGCGACCCAGCCGGCCT
GGACGGCAGCGGATCTCGGAAAGATCACGGTGCCGGTCACGCTCGCCATCGGCGATCACGACGAAGCCGTGAAGCTCGAC
CATACCGAGGTGATGGCGAAAGACATTCCGGGCGCAAAGCTGGTGATCCTGAAAGAGGCCAGCCATTTCGCCATGCTGCA
GGATCCCGCGGGCTACAATGCGATGATCCGGGAGGCGATGGCGGGCCGCTGA

Upstream 100 bases:

>100_bases
ACCTATGCAGCTGACGATTGTCAGGCAGTAGCGATGCGATATCTTCCTTTCGGGCCATAACGGCCCGAGGGGCCATAACT
GCCCGACAAGGGGGATGATG

Downstream 100 bases:

>100_bases
AAACCGCTGCGGGCGCTCCCCTCTTTCCATCGCTGCTTAATTGGTTTATAGGCAGCGCCAGCGTCAGGTTCGCCTGCTCG
CATTCACGGCCAAAGCTGGA

Product: alpha/beta hydrolase fold protein

Products: NA

Alternate protein names: 3-oxoadipate enol-lactonase II; Beta-ketoadipate enol-lactone hydrolase II; Enol-lactone hydrolase II [H]

Number of amino acids: Translated: 283; Mature: 283

Protein sequence:

>283_residues
MRATAIGMLTLFSMFLTVTGAQSGERWAELPAFPAMPVPKTSGMAEVNDIKMYYAEYGEGEPMLFIHGGLGNADVWGHQI
AEFSKDHLVIVADSRGHGRSTRSQKPFGYDLMTSDYAALLDHLKIGKVTLVGWSNGGIIGIDMAMNHPEKLTRVIAQAAN
VTTDGVKPDVLSNKTFNDYINVAGEQYRKLSPTPNEYDAFVTQISEMWATQPAWTAADLGKITVPVTLAIGDHDEAVKLD
HTEVMAKDIPGAKLVILKEASHFAMLQDPAGYNAMIREAMAGR

Sequences:

>Translated_283_residues
MRATAIGMLTLFSMFLTVTGAQSGERWAELPAFPAMPVPKTSGMAEVNDIKMYYAEYGEGEPMLFIHGGLGNADVWGHQI
AEFSKDHLVIVADSRGHGRSTRSQKPFGYDLMTSDYAALLDHLKIGKVTLVGWSNGGIIGIDMAMNHPEKLTRVIAQAAN
VTTDGVKPDVLSNKTFNDYINVAGEQYRKLSPTPNEYDAFVTQISEMWATQPAWTAADLGKITVPVTLAIGDHDEAVKLD
HTEVMAKDIPGAKLVILKEASHFAMLQDPAGYNAMIREAMAGR
>Mature_283_residues
MRATAIGMLTLFSMFLTVTGAQSGERWAELPAFPAMPVPKTSGMAEVNDIKMYYAEYGEGEPMLFIHGGLGNADVWGHQI
AEFSKDHLVIVADSRGHGRSTRSQKPFGYDLMTSDYAALLDHLKIGKVTLVGWSNGGIIGIDMAMNHPEKLTRVIAQAAN
VTTDGVKPDVLSNKTFNDYINVAGEQYRKLSPTPNEYDAFVTQISEMWATQPAWTAADLGKITVPVTLAIGDHDEAVKLD
HTEVMAKDIPGAKLVILKEASHFAMLQDPAGYNAMIREAMAGR

Specific function: Not Clear. Seems To Be Implicated In The Early Steps Of Biotin Biosynthesis. [C]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Homo sapiens, GI221316588, Length=255, Percent_Identity=25.4901960784314, Blast_Score=76, Evalue=3e-14,
Organism=Drosophila melanogaster, GI24649021, Length=261, Percent_Identity=22.9885057471264, Blast_Score=65, Evalue=6e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000073
- InterPro:   IPR012790 [H]

Pfam domain/function: PF00561 Abhydrolase_1 [H]

EC number: =3.1.1.24 [H]

Molecular weight: Translated: 30816; Mature: 30816

Theoretical pI: Translated: 5.55; Mature: 5.55

Prosite motif: PS00120 LIPASE_SER

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
5.3 %Met     (Translated Protein)
5.3 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
5.3 %Met     (Mature Protein)
5.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRATAIGMLTLFSMFLTVTGAQSGERWAELPAFPAMPVPKTSGMAEVNDIKMYYAEYGEG
CCCHHHHHHHHHHHHHHHCCCCCCCHHHHCCCCCCCCCCCCCCCCCHHHEEEEEEECCCC
EPMLFIHGGLGNADVWGHQIAEFSKDHLVIVADSRGHGRSTRSQKPFGYDLMTSDYAALL
CEEEEEECCCCCCCHHHHHHHHCCCCCEEEEECCCCCCCCCCCCCCCCCCHHHHHHHHHH
DHLKIGKVTLVGWSNGGIIGIDMAMNHPEKLTRVIAQAANVTTDGVKPDVLSNKTFNDYI
HHCCCCEEEEEEECCCCEEEEEECCCCHHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHH
NVAGEQYRKLSPTPNEYDAFVTQISEMWATQPAWTAADLGKITVPVTLAIGDHDEAVKLD
HHCCHHHHCCCCCCCHHHHHHHHHHHHHCCCCCCCHHCCCEEEEEEEEEECCCCCEEEEC
HTEVMAKDIPGAKLVILKEASHFAMLQDPAGYNAMIREAMAGR
HHHHHHHCCCCCEEEEEECCCCEEEEECCCCHHHHHHHHHCCC
>Mature Secondary Structure
MRATAIGMLTLFSMFLTVTGAQSGERWAELPAFPAMPVPKTSGMAEVNDIKMYYAEYGEG
CCCHHHHHHHHHHHHHHHCCCCCCCHHHHCCCCCCCCCCCCCCCCCHHHEEEEEEECCCC
EPMLFIHGGLGNADVWGHQIAEFSKDHLVIVADSRGHGRSTRSQKPFGYDLMTSDYAALL
CEEEEEECCCCCCCHHHHHHHHCCCCCEEEEECCCCCCCCCCCCCCCCCCHHHHHHHHHH
DHLKIGKVTLVGWSNGGIIGIDMAMNHPEKLTRVIAQAANVTTDGVKPDVLSNKTFNDYI
HHCCCCEEEEEEECCCCEEEEEECCCCHHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHH
NVAGEQYRKLSPTPNEYDAFVTQISEMWATQPAWTAADLGKITVPVTLAIGDHDEAVKLD
HHCCHHHHCCCCCCCHHHHHHHHHHHHHCCCCCCCHHCCCEEEEEEEEEECCCCCEEEEC
HTEVMAKDIPGAKLVILKEASHFAMLQDPAGYNAMIREAMAGR
HHHHHHHCCCCCEEEEEECCCCEEEEECCCCHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8125318; 670169 [H]