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The map label for this gene is yfkE [H]

Identifier: 209551617

GI number: 209551617

Start: 4219802

End: 4220896

Strand: Reverse

Name: yfkE [H]

Synonym: Rleg2_4046

Alternate gene names: 209551617

Gene position: 4220896-4219802 (Counterclockwise)

Preceding gene: 209551619

Following gene: 209551616

Centisome position: 93.01

GC content: 61.74

Gene sequence:

>1095_bases
TTGAGCCCACTTTTCAAAGAGATTCGCGGCAGCCCCATACTCTGGCTGCTGGCCGCTGTGCCGGTGGTGTTCTTGGCTGC
GGCACTCTTTCCCGAAGCCCACACGGCGCTTTTCGTCCTGTCGGTGTTGGCCATCGTGCCGCTCGCCGGGCTACTCAGCC
ATGCGACGGAATCTGTTGCCGCCAAGACGGGTGACGCAGCCGGCGGGCTGCTGAATGCGACCCTCGGAAATCTCACCGAG
CTGGTCATCGCGCTGGCTGCGCTGCAGGCCGGTCAATATACGCTGGTCAAGGCATCGATCGCCGGAGCGATCGTCACCAA
CACGCTGTTCATGCTGGGCGCTTCGTTTCTGCTCGGCGGGCTCAAATACCACATTCAGGAATTCAACCGCGCCAGTGCGC
GTATTCAGGCCGGCCTGCTTTTCCTGGCTACAGTCGCCCTGCTGATGCCTTCGGTGCTTGGCGGATTGGACACGGCATCG
GTTGCCTCGGTCACCCAAACGCTCAGCCTCAGCCTAGCCGTTCTGCTGATCATCGGATACGGCCTGGGGCTGTTGTTCAC
GCTTGGGACGCATCGAGAATTTTTCTCTTCAGCAGATCATGCCGAGGCCGGTGAGGCGCCGTGGCCGATCGGCCTTGCTC
TCGGCACGCTTGCCGGGGTCACTGTCCTTGTGGCCTTGGTGAGCGAGATTTTCGTCGAATCCGTGCAGGAAGCGGCCGTC
GCCTTCGGAATGACCCCCGCCTTTGTCGGTTTCATCGTCGTCTCATTGGTCGGGGCCGCCGCCGAAATGGCCTCGGCGTT
TTCCGGCGCGCGTAAGAACCGGCTCGATCTGAGCGTCGGCATCGCGCTCGGGAGCGCGTCCCAGATCGCGTTGTTCGTCG
CGCCGGTCCTGGTCTTGATGAGTTACGTGATCGGCCCGTCACCGATGGATCTGCAGTTCTGGCCGGGGGCCGTGATGATG
ATGTTCCTTGCTACAGTGACTGCGATGTTTGTCACCAACAGCGGGCGATCGGCGTGGTTCGTCGGCGTCCTGGTGCTGAT
GGTCTACATCATCTTCGCGATAACGCTGTATGTCTTGCCGCCGGCAGTGCGATGA

Upstream 100 bases:

>100_bases
ATAGGGGAACGAGCAAGGCAGAATCCTCGGCGTTGGGTAGGAGCAGATCATCTCCCGCTGACATTGCTGCAACGCGCGAG
GATAATCACGGGGGGAAAGG

Downstream 100 bases:

>100_bases
GGTTCCGCGTTCCCAAGCAATCAGGCGGCGAACCGCAAACTCAAAAGATGAGGCGGCTGTTCTTCATCGCACTCGCAAAG
CAGCTGCGCGTCATCTGGCC

Product: calcium/proton antiporter, CaCA family

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 364; Mature: 363

Protein sequence:

>364_residues
MSPLFKEIRGSPILWLLAAVPVVFLAAALFPEAHTALFVLSVLAIVPLAGLLSHATESVAAKTGDAAGGLLNATLGNLTE
LVIALAALQAGQYTLVKASIAGAIVTNTLFMLGASFLLGGLKYHIQEFNRASARIQAGLLFLATVALLMPSVLGGLDTAS
VASVTQTLSLSLAVLLIIGYGLGLLFTLGTHREFFSSADHAEAGEAPWPIGLALGTLAGVTVLVALVSEIFVESVQEAAV
AFGMTPAFVGFIVVSLVGAAAEMASAFSGARKNRLDLSVGIALGSASQIALFVAPVLVLMSYVIGPSPMDLQFWPGAVMM
MFLATVTAMFVTNSGRSAWFVGVLVLMVYIIFAITLYVLPPAVR

Sequences:

>Translated_364_residues
MSPLFKEIRGSPILWLLAAVPVVFLAAALFPEAHTALFVLSVLAIVPLAGLLSHATESVAAKTGDAAGGLLNATLGNLTE
LVIALAALQAGQYTLVKASIAGAIVTNTLFMLGASFLLGGLKYHIQEFNRASARIQAGLLFLATVALLMPSVLGGLDTAS
VASVTQTLSLSLAVLLIIGYGLGLLFTLGTHREFFSSADHAEAGEAPWPIGLALGTLAGVTVLVALVSEIFVESVQEAAV
AFGMTPAFVGFIVVSLVGAAAEMASAFSGARKNRLDLSVGIALGSASQIALFVAPVLVLMSYVIGPSPMDLQFWPGAVMM
MFLATVTAMFVTNSGRSAWFVGVLVLMVYIIFAITLYVLPPAVR
>Mature_363_residues
SPLFKEIRGSPILWLLAAVPVVFLAAALFPEAHTALFVLSVLAIVPLAGLLSHATESVAAKTGDAAGGLLNATLGNLTEL
VIALAALQAGQYTLVKASIAGAIVTNTLFMLGASFLLGGLKYHIQEFNRASARIQAGLLFLATVALLMPSVLGGLDTASV
ASVTQTLSLSLAVLLIIGYGLGLLFTLGTHREFFSSADHAEAGEAPWPIGLALGTLAGVTVLVALVSEIFVESVQEAAVA
FGMTPAFVGFIVVSLVGAAAEMASAFSGARKNRLDLSVGIALGSASQIALFVAPVLVLMSYVIGPSPMDLQFWPGAVMMM
FLATVTAMFVTNSGRSAWFVGVLVLMVYIIFAITLYVLPPAVR

Specific function: Unknown

COG id: COG0387

COG function: function code P; Ca2+/H+ antiporter

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the sodium/potassium/calcium exchanger family [H]

Homologues:

Organism=Saccharomyces cerevisiae, GI6320075, Length=368, Percent_Identity=33.4239130434783, Blast_Score=184, Evalue=3e-47,
Organism=Saccharomyces cerevisiae, GI6324008, Length=377, Percent_Identity=25.9946949602122, Blast_Score=104, Evalue=2e-23,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004713
- InterPro:   IPR004798
- InterPro:   IPR004837 [H]

Pfam domain/function: PF01699 Na_Ca_ex [H]

EC number: NA

Molecular weight: Translated: 37636; Mature: 37505

Theoretical pI: Translated: 6.00; Mature: 6.00

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSPLFKEIRGSPILWLLAAVPVVFLAAALFPEAHTALFVLSVLAIVPLAGLLSHATESVA
CCCHHHHHCCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AKTGDAAGGLLNATLGNLTELVIALAALQAGQYTLVKASIAGAIVTNTLFMLGASFLLGG
HCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHH
LKYHIQEFNRASARIQAGLLFLATVALLMPSVLGGLDTASVASVTQTLSLSLAVLLIIGY
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHH
GLGLLFTLGTHREFFSSADHAEAGEAPWPIGLALGTLAGVTVLVALVSEIFVESVQEAAV
HHHHHHHHCCHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AFGMTPAFVGFIVVSLVGAAAEMASAFSGARKNRLDLSVGIALGSASQIALFVAPVLVLM
HHCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEEEECCHHHHHHHHHHHHHHH
SYVIGPSPMDLQFWPGAVMMMFLATVTAMFVTNSGRSAWFVGVLVLMVYIIFAITLYVLP
HHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHCC
PAVR
CCCC
>Mature Secondary Structure 
SPLFKEIRGSPILWLLAAVPVVFLAAALFPEAHTALFVLSVLAIVPLAGLLSHATESVA
CCHHHHHCCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AKTGDAAGGLLNATLGNLTELVIALAALQAGQYTLVKASIAGAIVTNTLFMLGASFLLGG
HCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHH
LKYHIQEFNRASARIQAGLLFLATVALLMPSVLGGLDTASVASVTQTLSLSLAVLLIIGY
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHH
GLGLLFTLGTHREFFSSADHAEAGEAPWPIGLALGTLAGVTVLVALVSEIFVESVQEAAV
HHHHHHHHCCHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AFGMTPAFVGFIVVSLVGAAAEMASAFSGARKNRLDLSVGIALGSASQIALFVAPVLVLM
HHCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEEEECCHHHHHHHHHHHHHHH
SYVIGPSPMDLQFWPGAVMMMFLATVTAMFVTNSGRSAWFVGVLVLMVYIIFAITLYVLP
HHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHCC
PAVR
CCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 8969503; 9384377 [H]