Click here to switch to the map view.

The map label for this gene is rnd [H]

Identifier: 209551599

GI number: 209551599

Start: 4201442

End: 4202068

Strand: Direct

Name: rnd [H]

Synonym: Rleg2_4028

Alternate gene names: 209551599

Gene position: 4201442-4202068 (Clockwise)

Preceding gene: 209551598

Following gene: 209551600

Centisome position: 92.58

GC content: 62.52

Gene sequence:

>627_bases
ATGGCCGCCACCATACGTTATCACGAAGGCGATATTTCCGCAGCCGATGCCGCGCGTTACACCGGCGCGATTGCCATCGA
CACCGAAACGCTCGGCCTGGTGCCGCGCCGGGACCGGCTCTGCGTCGTCCAGCTTTCACCGGGTGACGGCACCGCCGACG
TCATCCGCATCGCCTCCGGCCAGAAAGAGGCTCCCAATCTCGTCGCCCTGCTCGAAGATCCGACCCATCAGAAGATCTTT
CATTACGGCCGCTTCGATATTGCCGTGCTCTTCCACACATTCGGGGTCACGACGAACCCGGTCTTCTGCACCAAGATCGC
CTCGCGCCTGATCCGCACCTATACGGATCGCCACGGCCTCAAGGACAATCTCAAGGAGATGCTCGACGTCGATATCTCCA
AGGCGCAGCAGTCTTCCGATTGGGCGGCCGAGACGCTGTCTCCGGCCCAGCTCGAATATGCCGCTTCCGATGTGCTTTAT
CTGCACGCGTTGCGCGACAAGCTGACGGAACGCCTGCTCCGCGACGGCCGCTTCGACCATGCGACGGCCTGCTTCGCATT
CCTGCCGACCCGCGCCAAGCTCGACCTGCTCGGCTGGGAAGAGGCCGATATCTTCGCCCATAGCTGA

Upstream 100 bases:

>100_bases
CGCTATAGCGCACTGCATAATTCCTTAAATCGCCATCGATTTAAGGATAAAATTATGCGGCAATTCAAAGTGCTACAGCG
TCCTAAGGAAAGACAGTCTC

Downstream 100 bases:

>100_bases
GTAAATTGCCTGCGGCACGCATGAAAACAAAGATCGTGGATCGGCATGTCCGCGGCGTTAGCGATTCGTTAACGCCTCTT
TTCTAAAATTCCCGTTAATA

Product: 3'-5' exonuclease

Products: NA

Alternate protein names: RNase D [H]

Number of amino acids: Translated: 208; Mature: 207

Protein sequence:

>208_residues
MAATIRYHEGDISAADAARYTGAIAIDTETLGLVPRRDRLCVVQLSPGDGTADVIRIASGQKEAPNLVALLEDPTHQKIF
HYGRFDIAVLFHTFGVTTNPVFCTKIASRLIRTYTDRHGLKDNLKEMLDVDISKAQQSSDWAAETLSPAQLEYAASDVLY
LHALRDKLTERLLRDGRFDHATACFAFLPTRAKLDLLGWEEADIFAHS

Sequences:

>Translated_208_residues
MAATIRYHEGDISAADAARYTGAIAIDTETLGLVPRRDRLCVVQLSPGDGTADVIRIASGQKEAPNLVALLEDPTHQKIF
HYGRFDIAVLFHTFGVTTNPVFCTKIASRLIRTYTDRHGLKDNLKEMLDVDISKAQQSSDWAAETLSPAQLEYAASDVLY
LHALRDKLTERLLRDGRFDHATACFAFLPTRAKLDLLGWEEADIFAHS
>Mature_207_residues
AATIRYHEGDISAADAARYTGAIAIDTETLGLVPRRDRLCVVQLSPGDGTADVIRIASGQKEAPNLVALLEDPTHQKIFH
YGRFDIAVLFHTFGVTTNPVFCTKIASRLIRTYTDRHGLKDNLKEMLDVDISKAQQSSDWAAETLSPAQLEYAASDVLYL
HALRDKLTERLLRDGRFDHATACFAFLPTRAKLDLLGWEEADIFAHS

Specific function: Cleaves multimeric tRNA precursor at the spacer region. Contribute to the 3' maturation of several stable RNAs [H]

COG id: COG0349

COG function: function code J; Ribonuclease D

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HRDC domain [H]

Homologues:

Organism=Escherichia coli, GI1788105, Length=159, Percent_Identity=31.4465408805031, Blast_Score=67, Evalue=1e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002562
- InterPro:   IPR002121
- InterPro:   IPR010997
- InterPro:   IPR006292
- InterPro:   IPR012337 [H]

Pfam domain/function: PF01612 3_5_exonuc; PF00570 HRDC [H]

EC number: =3.1.13.5 [H]

Molecular weight: Translated: 23100; Mature: 22969

Theoretical pI: Translated: 6.08; Mature: 6.08

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
1.0 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
0.5 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAATIRYHEGDISAADAARYTGAIAIDTETLGLVPRRDRLCVVQLSPGDGTADVIRIASG
CCEEEEEECCCCCHHHHHHHCCEEEECCHHCCCCCCCCCEEEEEECCCCCCHHEEEECCC
QKEAPNLVALLEDPTHQKIFHYGRFDIAVLFHTFGVTTNPVFCTKIASRLIRTYTDRHGL
CCCCCCEEEEECCCCHHHHHHCCCHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHCCCC
KDNLKEMLDVDISKAQQSSDWAAETLSPAQLEYAASDVLYLHALRDKLTERLLRDGRFDH
HHHHHHHHHCHHHHHHCCCCHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCH
ATACFAFLPTRAKLDLLGWEEADIFAHS
HHHHHHHCCCCCEEEECCCCCCCEEECC
>Mature Secondary Structure 
AATIRYHEGDISAADAARYTGAIAIDTETLGLVPRRDRLCVVQLSPGDGTADVIRIASG
CEEEEEECCCCCHHHHHHHCCEEEECCHHCCCCCCCCCEEEEEECCCCCCHHEEEECCC
QKEAPNLVALLEDPTHQKIFHYGRFDIAVLFHTFGVTTNPVFCTKIASRLIRTYTDRHGL
CCCCCCEEEEECCCCHHHHHHCCCHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHCCCC
KDNLKEMLDVDISKAQQSSDWAAETLSPAQLEYAASDVLYLHALRDKLTERLLRDGRFDH
HHHHHHHHHCHHHHHHCCCCHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCH
ATACFAFLPTRAKLDLLGWEEADIFAHS
HHHHHHHCCCCCEEEECCCCCCCEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 3041371; 9097040; 9278503; 8107670 [H]