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The map label for this gene is pdxY [H]

Identifier: 209551483

GI number: 209551483

Start: 4053888

End: 4054763

Strand: Reverse

Name: pdxY [H]

Synonym: Rleg2_3912

Alternate gene names: 209551483

Gene position: 4054763-4053888 (Counterclockwise)

Preceding gene: 209551486

Following gene: 209551482

Centisome position: 89.35

GC content: 65.87

Gene sequence:

>876_bases
ATGTCGGAAAATGCAGCGGGCGCAGTCATCGTCATCTCCAGTCATGTGGTGCGCGGCTCGGTCGGAAACCGGGCGGCCGT
CTTTGCGCTGGAAACGCTTGGTCATCCAGTCTGGGCGCTGCCGACCATCGTGCTGCCCTGGCATCCCGGCCACGGCCGCT
CGACGCGGCTGACATTTGCGGAAGCGGATTTCGACGCGGCGATCGACGATCTGATCCGGGCGCCCTGGATCGGCGAAGTC
AGGGCAGTGCTTTCGGGCTATTTCGGCAATGCCGCCCAGGCGCGCTCCGTGTCCCGGCTGATCGCCGCGCTCAGGCAAGA
TAATCCCGAGCTTCTCTATGTCTGCGACCCCGTCATGGGCGATCTCGGCGGTCTCTACGTGCCCGAAGCGACCGCCGAAG
CCATTCGCGACCATCTCATCCCGCTTGCTTCACTCGCGACGCCGAACCGCTACGAACTCGCATGGCTGTCCGGGGCAGCG
CTTGACGACAACAGCGCGATCATGGAAGCAGCGCTGGCGCTCGGGCCGTCGCGCATGCTCGTCACCTCGGCCGTGCCGAT
GATGGCGGGCGGTACCGGCAATCTCTATCTTTCCGGCCGTCACGCGCTTCTGGCCGAGCACCGCGCCGTCGAAAACGCGC
CGAATGGTCTCGGCGACCTGCTGGCTGCCGTCTTCCTGTCGCGCCTTCTATCCGGCCTCGAGGACGAAAAGGCGCTGCAG
CTTGCCACGGCCAGCGTCTTCGAGGTGCTGGCGCGCGCCGTCAAGCGCGGCAGTAACGAGCTGATGCTGGCGAGCGATGC
TTCCAGCCTTTCGACGCCGATGGCCATGGTGCAGATGCGCCGGCTCCTGCACCCGGCGCAGCGGCGGAAAAAATGA

Upstream 100 bases:

>100_bases
TTTTTCGTTCCGCCGCACATTTCCATGCTCACGTGAAGAATGGTTGACAGTGCGGCGTCAAAAAGATCATCAAACGCGGT
CATCATTCGGATCTTGTCTC

Downstream 100 bases:

>100_bases
CGCATCCATCAATGTGCTCATTTTGCAGTGCAGCAGTTGATCTTGTCTTCCGCGCGCGCTAATCCAGAAGCATGCAGCGT
TTTCCAAATTCCCTTCTGGA

Product: pyridoxamine kinase

Products: NA

Alternate protein names: PM kinase [H]

Number of amino acids: Translated: 291; Mature: 290

Protein sequence:

>291_residues
MSENAAGAVIVISSHVVRGSVGNRAAVFALETLGHPVWALPTIVLPWHPGHGRSTRLTFAEADFDAAIDDLIRAPWIGEV
RAVLSGYFGNAAQARSVSRLIAALRQDNPELLYVCDPVMGDLGGLYVPEATAEAIRDHLIPLASLATPNRYELAWLSGAA
LDDNSAIMEAALALGPSRMLVTSAVPMMAGGTGNLYLSGRHALLAEHRAVENAPNGLGDLLAAVFLSRLLSGLEDEKALQ
LATASVFEVLARAVKRGSNELMLASDASSLSTPMAMVQMRRLLHPAQRRKK

Sequences:

>Translated_291_residues
MSENAAGAVIVISSHVVRGSVGNRAAVFALETLGHPVWALPTIVLPWHPGHGRSTRLTFAEADFDAAIDDLIRAPWIGEV
RAVLSGYFGNAAQARSVSRLIAALRQDNPELLYVCDPVMGDLGGLYVPEATAEAIRDHLIPLASLATPNRYELAWLSGAA
LDDNSAIMEAALALGPSRMLVTSAVPMMAGGTGNLYLSGRHALLAEHRAVENAPNGLGDLLAAVFLSRLLSGLEDEKALQ
LATASVFEVLARAVKRGSNELMLASDASSLSTPMAMVQMRRLLHPAQRRKK
>Mature_290_residues
SENAAGAVIVISSHVVRGSVGNRAAVFALETLGHPVWALPTIVLPWHPGHGRSTRLTFAEADFDAAIDDLIRAPWIGEVR
AVLSGYFGNAAQARSVSRLIAALRQDNPELLYVCDPVMGDLGGLYVPEATAEAIRDHLIPLASLATPNRYELAWLSGAAL
DDNSAIMEAALALGPSRMLVTSAVPMMAGGTGNLYLSGRHALLAEHRAVENAPNGLGDLLAAVFLSRLLSGLEDEKALQL
ATASVFEVLARAVKRGSNELMLASDASSLSTPMAMVQMRRLLHPAQRRKK

Specific function: Phosphorylates B6 vitamers; functions in a salvage pathway. Uses pyridoxamine [H]

COG id: COG2240

COG function: function code H; Pyridoxal/pyridoxine/pyridoxamine kinase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the pyridoxine kinase family [H]

Homologues:

Organism=Homo sapiens, GI4505701, Length=293, Percent_Identity=28.3276450511945, Blast_Score=114, Evalue=1e-25,
Organism=Escherichia coli, GI1788758, Length=264, Percent_Identity=31.8181818181818, Blast_Score=119, Evalue=3e-28,
Organism=Escherichia coli, GI1787924, Length=276, Percent_Identity=28.6231884057971, Blast_Score=101, Evalue=7e-23,
Organism=Caenorhabditis elegans, GI17507759, Length=180, Percent_Identity=32.2222222222222, Blast_Score=101, Evalue=4e-22,
Organism=Caenorhabditis elegans, GI17507757, Length=192, Percent_Identity=31.7708333333333, Blast_Score=98, Evalue=5e-21,
Organism=Saccharomyces cerevisiae, GI6320806, Length=257, Percent_Identity=28.7937743190661, Blast_Score=99, Evalue=9e-22,
Organism=Saccharomyces cerevisiae, GI6324354, Length=304, Percent_Identity=27.6315789473684, Blast_Score=89, Evalue=7e-19,
Organism=Drosophila melanogaster, GI45553007, Length=292, Percent_Identity=29.1095890410959, Blast_Score=123, Evalue=2e-28,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013749
- InterPro:   IPR004625 [H]

Pfam domain/function: PF08543 Phos_pyr_kin [H]

EC number: =2.7.1.35 [H]

Molecular weight: Translated: 30913; Mature: 30782

Theoretical pI: Translated: 6.73; Mature: 6.73

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSENAAGAVIVISSHVVRGSVGNRAAVFALETLGHPVWALPTIVLPWHPGHGRSTRLTFA
CCCCCCCEEEEEECCEEECCCCCCHHEEEHHHHCCCHHHCCEEEEECCCCCCCCEEEEEE
EADFDAAIDDLIRAPWIGEVRAVLSGYFGNAAQARSVSRLIAALRQDNPELLYVCDPVMG
CCCHHHHHHHHHHCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCCEEEEECHHHH
DLGGLYVPEATAEAIRDHLIPLASLATPNRYELAWLSGAALDDNSAIMEAALALGPSRML
CCCCEECCHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCCCCCHHHHHHHHHCCCCHHH
VTSAVPMMAGGTGNLYLSGRHALLAEHRAVENAPNGLGDLLAAVFLSRLLSGLEDEKALQ
HHHHCHHHCCCCCCEEECCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCCCHHHHHH
LATASVFEVLARAVKRGSNELMLASDASSLSTPMAMVQMRRLLHPAQRRKK
HHHHHHHHHHHHHHHCCCCCEEEEECCHHHHHHHHHHHHHHHHCHHHHCCC
>Mature Secondary Structure 
SENAAGAVIVISSHVVRGSVGNRAAVFALETLGHPVWALPTIVLPWHPGHGRSTRLTFA
CCCCCCEEEEEECCEEECCCCCCHHEEEHHHHCCCHHHCCEEEEECCCCCCCCEEEEEE
EADFDAAIDDLIRAPWIGEVRAVLSGYFGNAAQARSVSRLIAALRQDNPELLYVCDPVMG
CCCHHHHHHHHHHCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCCEEEEECHHHH
DLGGLYVPEATAEAIRDHLIPLASLATPNRYELAWLSGAALDDNSAIMEAALALGPSRML
CCCCEECCHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCCCCCHHHHHHHHHCCCCHHH
VTSAVPMMAGGTGNLYLSGRHALLAEHRAVENAPNGLGDLLAAVFLSRLLSGLEDEKALQ
HHHHCHHHCCCCCCEEECCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCCCHHHHHH
LATASVFEVLARAVKRGSNELMLASDASSLSTPMAMVQMRRLLHPAQRRKK
HHHHHHHHHHHHHHHCCCCCEEEEECCHHHHHHHHHHHHHHHHCHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA