Click here to switch to the map view.

The map label for this gene is pyc [H]

Identifier: 209551410

GI number: 209551410

Start: 3971135

End: 3974599

Strand: Reverse

Name: pyc [H]

Synonym: Rleg2_3839

Alternate gene names: 209551410

Gene position: 3974599-3971135 (Counterclockwise)

Preceding gene: 209551411

Following gene: 209551409

Centisome position: 87.59

GC content: 63.26

Gene sequence:

>3465_bases
TTGCCCATTTCCAAGATTCTCGTTGCCAATCGCTCCGAAATTGCCATTCGCGTGTTCCGCGCGGCCAACGAGCTTGGAAT
AAAAACCGTGGCGATCTGGGCAGAAGAGGACAAGCTGGCGCTGCATCGCTTCAAGGCGGACGAAAGCTACCAGGTCGGCC
GCGGTCCGCATCTTGCGCGTGATCTCGGACCGATCGAAAGCTATCTGTCGATCGACGAGGTGATCCGCGTCGCCAAGCTC
TCGGGCGCCGACGCCATTCACCCGGGTTACGGCCTGCTGTCGGAAAGCCCCGAATTCGTCGATGCCTGCAACAAGGCCGG
TATCATCTTCATCGGCCCGAGGGCCGATACGATGCGCCAGCTCGGCAACAAGGTCGCGGCCCGCAATCTGGCGATCTCGG
TCGGCGTGCCTGTCGTGCCGGCGACCGAGCCGCTGCCCGACGATATGGCCGTGGTGGCGAAGATGGCGAAAGAGATCGGT
TATCCCGTCATGCTGAAGGCCTCCTGGGGCGGCGGCGGGCGCGGCATGCGCGCCATCCGCGACCCGAAGGATCTCGCCCG
TGAGGTGACCGAGGCCAAGCGCGAGGCGATGGCCGCCTTCGGCAAGGACGAGGTCTATCTGGAAAAGCTGGTCGAACGCG
CCCGCCACGTCGAAAGCCAGGTTCTCGGCGATACGCACGGCAATGTCGTGCATCTGTTCGAGCGTGACTGCTCCATCCAG
CGCCGCAACCAGAAGGTCGTCGAGCGGGCGCCGGCCCCCTATCTTTCCGAGGCGCAGCGCCAGGAGCTCGCCGCCTATTC
GCTGAAGATCGCAGCGGCGACCAATTATGTCGGCGCCGGCACCGTCGAATATCTGATGGATGCCGATACCGGCAAATTCT
ACTTCATCGAGGTCAATCCGCGCATCCAGGTCGAGCACACGGTGACCGAAGTCGTTACCGGCATCGACATCGTCAAGGCG
CAGATCCACATCCTTGACGGCGCCGCGATCGGCACGCCGGAATCCGGCGTTCCCGCTCAAGCCGATATCCGTCTCAACGG
CCATGCGCTGCAGTGCCGCATCACCACCGAGGATCCGGAACACAACTTCATTCCGGATTACGGCCGCATCACCGCCTATC
GCTCGGCTTCCGGTTTCGGCATCCGCCTCGACGGCGGCACCTCCTATTCCGGTGCCATCATCACCCGCTTTTACGATCCG
CTGCTCGTCAAGGTCACGGCCTGGGCGCCGAACCCCTCCGAAGCGATTTCCCGCATGGACCGGGCGCTGCGCGAATTCCG
TATTCGCGGCGTCGCCACCAACCTGACCTTCCTCGAAGCGATCATCGGCCATCCGAAATTCCGCGACAACAGCTACACCA
CGCGCTTCATCGACACGACGCCGGAACTCTTCCAGCAGGTTAAGCGCCAGGACCGCGCGACGAAGCTGCTGACCTATCTC
GCCGACGTCACCGTCAACGGTCATCCGGAAGCCAAGGATAGGCCAAGGCCGCTTGATAACGCCGCCCAGCCGGTGGTGCC
CTATGGCAACGGCAATGGCGTCAAGGACGGCACCAAGCAGCTTCTCGACACCCTCGGCCCGAAGAAATTCGGCGAATGGA
TGCGCAACGAAAAGCGCGTGCTTCTGACCGACACGACGATGCGCGACGGCCACCAGTCGCTGCTCGCCACCCGCATGCGT
ACCTATGACATCGCCCGCATCGCCGGCACCTATGCGCATGCGCTGCCGAACCTGCTCTCGCTGGAATGTTGGGGCGGCGC
CACTTTCGACGTCTCGATGCGCTTCCTGACGGAAGATCCGTGGGAGCGCCTGGCGCTGATCCGCGAGGGCGCGCCGAACC
TGCTGCTGCAGATGCTGCTGCGCGGCGCCAACGGTGTCGGCTACACCAACTATCCCGACAATGTCGTCAAATACTTCGTC
CGCCAGGCGGCCCGCGGCGGCATCGATCTCTTCCGCGTCTTCGACTGCCTGAACTGGGTCGAGAACATGCGCGTCTCGAT
GGATGCCATCGCCGAAGAGAACAAGCTCTGCGAGGCGGCGATCTGCTATACCGGCGATATTCTCAATTCGGCCCGCCCGA
AATATGACCTGAAATATTATACCGACCTTGCGGTCGAGCTGGAAAAGGCCGGCGCCCATATCATCGCGCTCAAGGACATG
GCGGGCCTGCTCAAGCCTGCGGCGGCGAAGGTTCTGTTCAAGGCGCTGCGCGAGGCGACCAGCCTGCCGATCCATTTCCA
CACGCATGACACATCGGGCATTGCCGCGGCGACCGTTCTTGCCGCGGTCGACGCCGGCGTCGATGCCGTCGATGCGGCCA
TGGATGCGCTGTCCGGCAATACGTCGCAGCCCTGTCTCGGCTCGATCGTCGAGGCGCTGCGCGGTACGGAGCGCGATCCG
GGTCTCGATCCGGAATGGATCCGCCGCGTCTCCTTCTATTGGGAAGCGGTGCGCAACCAATATGCCGCCTTCGAAAGCGA
TCTGAAGGGGCCGGCATCGGAAGTCTATCTGCATGAAATGCCGGGCGGTCAGTTCACCAACCTCAAGGAACAGGCCCGCT
CGCTGGGTCTGGAGACCCGCTGGCATCGGGTGGCGCAGGCTTATGCCGACGCCAACCAGATGTTCGGCGATATCGTTAAG
GTGACGCCGTCCTCCAAGGTGGTCGGCGATATGGCGCTGATGATGGTGAGCCAGGACCTGACGGTCGCCGACGTCGTCAG
CCCCGACAAGGAGGTCTCCTTCCCGGAATCGGTGGTGTCGATGCTGAAGGGCGATCTCGGCCAGCCGCCGTCGGGATGGC
CGGAAGCGCTGCAGAAGAAGGCGCTGAAGGGCGACAAGCCCTACACGGTGCGTCCCGGCTCGCTGCTGAAGGAAGCCGAT
CTCGATGCCGAACGTAAGGTCATCGAGACGAAGCTCGAGCGCGAGGTCAGCGATTTCGAGTTCGCCTCCTATCTGATGTA
TCCGAAGGTCTTCACCGATTTCGCGCTCGCCTCCGATACCTACGGCCCGGTCTCGGTGCTGCCGACGCCTGCCTATTTCT
ACGGGCTGGGGGATGGCGAAGAACTGTTTGCCGATATCGAACGCGGCAAGACGCTCGTCATCGTCAACCAGGCGATGAGC
GCCACCGACAGCCAGGGCATGGTCACCATCTTTTTCGAGCTCAACGGCCAGCCGCGCCGCATCAAGGTGCCGGACCGGGC
CCATGGGGCGACGGGGGCAGCGGTCCGCCGCAAGGCCGAACCGGGCAATGCCGTCCATGTCGGTGCGCCGATGCCGGGCG
TCATCTCACGCGTCTTCGTCTCTTCTGGCCAAGCGGTCAGTGCCGGCGACGTGCTCGTTTCGATCGAGGCGATGAAGATG
GAAACGGCGCTGCATGCGGAGAAGGACGGCACCATCGCCGAAGTGCTGGTCAAGGCGGGCGATCAGATCGACGCCAAGGA
CCTGCTCGTCGTCTATGGCGGTTAA

Upstream 100 bases:

>100_bases
TTTCGCAGTCGCAAGAGAAATTGAACTTCCTGTGACAAGAAGTTAAGAATTTCCTTCGCGGGTGCAGCATGCCCGCGTCT
GAACGTCTGAGGAGACCGTT

Downstream 100 bases:

>100_bases
GCAATGGGCGGCTGTTCTGCTACCGGCGGTCTGTAGCCAATCACCCGATTGTGTATGATCGGGCTGCCCAAAAGCTGATT
TTTTTGAAGAATTAGCCGCC

Product: pyruvate carboxylase

Products: NA

Alternate protein names: Pyruvic carboxylase; PYC [H]

Number of amino acids: Translated: 1154; Mature: 1153

Protein sequence:

>1154_residues
MPISKILVANRSEIAIRVFRAANELGIKTVAIWAEEDKLALHRFKADESYQVGRGPHLARDLGPIESYLSIDEVIRVAKL
SGADAIHPGYGLLSESPEFVDACNKAGIIFIGPRADTMRQLGNKVAARNLAISVGVPVVPATEPLPDDMAVVAKMAKEIG
YPVMLKASWGGGGRGMRAIRDPKDLAREVTEAKREAMAAFGKDEVYLEKLVERARHVESQVLGDTHGNVVHLFERDCSIQ
RRNQKVVERAPAPYLSEAQRQELAAYSLKIAAATNYVGAGTVEYLMDADTGKFYFIEVNPRIQVEHTVTEVVTGIDIVKA
QIHILDGAAIGTPESGVPAQADIRLNGHALQCRITTEDPEHNFIPDYGRITAYRSASGFGIRLDGGTSYSGAIITRFYDP
LLVKVTAWAPNPSEAISRMDRALREFRIRGVATNLTFLEAIIGHPKFRDNSYTTRFIDTTPELFQQVKRQDRATKLLTYL
ADVTVNGHPEAKDRPRPLDNAAQPVVPYGNGNGVKDGTKQLLDTLGPKKFGEWMRNEKRVLLTDTTMRDGHQSLLATRMR
TYDIARIAGTYAHALPNLLSLECWGGATFDVSMRFLTEDPWERLALIREGAPNLLLQMLLRGANGVGYTNYPDNVVKYFV
RQAARGGIDLFRVFDCLNWVENMRVSMDAIAEENKLCEAAICYTGDILNSARPKYDLKYYTDLAVELEKAGAHIIALKDM
AGLLKPAAAKVLFKALREATSLPIHFHTHDTSGIAAATVLAAVDAGVDAVDAAMDALSGNTSQPCLGSIVEALRGTERDP
GLDPEWIRRVSFYWEAVRNQYAAFESDLKGPASEVYLHEMPGGQFTNLKEQARSLGLETRWHRVAQAYADANQMFGDIVK
VTPSSKVVGDMALMMVSQDLTVADVVSPDKEVSFPESVVSMLKGDLGQPPSGWPEALQKKALKGDKPYTVRPGSLLKEAD
LDAERKVIETKLEREVSDFEFASYLMYPKVFTDFALASDTYGPVSVLPTPAYFYGLGDGEELFADIERGKTLVIVNQAMS
ATDSQGMVTIFFELNGQPRRIKVPDRAHGATGAAVRRKAEPGNAVHVGAPMPGVISRVFVSSGQAVSAGDVLVSIEAMKM
ETALHAEKDGTIAEVLVKAGDQIDAKDLLVVYGG

Sequences:

>Translated_1154_residues
MPISKILVANRSEIAIRVFRAANELGIKTVAIWAEEDKLALHRFKADESYQVGRGPHLARDLGPIESYLSIDEVIRVAKL
SGADAIHPGYGLLSESPEFVDACNKAGIIFIGPRADTMRQLGNKVAARNLAISVGVPVVPATEPLPDDMAVVAKMAKEIG
YPVMLKASWGGGGRGMRAIRDPKDLAREVTEAKREAMAAFGKDEVYLEKLVERARHVESQVLGDTHGNVVHLFERDCSIQ
RRNQKVVERAPAPYLSEAQRQELAAYSLKIAAATNYVGAGTVEYLMDADTGKFYFIEVNPRIQVEHTVTEVVTGIDIVKA
QIHILDGAAIGTPESGVPAQADIRLNGHALQCRITTEDPEHNFIPDYGRITAYRSASGFGIRLDGGTSYSGAIITRFYDP
LLVKVTAWAPNPSEAISRMDRALREFRIRGVATNLTFLEAIIGHPKFRDNSYTTRFIDTTPELFQQVKRQDRATKLLTYL
ADVTVNGHPEAKDRPRPLDNAAQPVVPYGNGNGVKDGTKQLLDTLGPKKFGEWMRNEKRVLLTDTTMRDGHQSLLATRMR
TYDIARIAGTYAHALPNLLSLECWGGATFDVSMRFLTEDPWERLALIREGAPNLLLQMLLRGANGVGYTNYPDNVVKYFV
RQAARGGIDLFRVFDCLNWVENMRVSMDAIAEENKLCEAAICYTGDILNSARPKYDLKYYTDLAVELEKAGAHIIALKDM
AGLLKPAAAKVLFKALREATSLPIHFHTHDTSGIAAATVLAAVDAGVDAVDAAMDALSGNTSQPCLGSIVEALRGTERDP
GLDPEWIRRVSFYWEAVRNQYAAFESDLKGPASEVYLHEMPGGQFTNLKEQARSLGLETRWHRVAQAYADANQMFGDIVK
VTPSSKVVGDMALMMVSQDLTVADVVSPDKEVSFPESVVSMLKGDLGQPPSGWPEALQKKALKGDKPYTVRPGSLLKEAD
LDAERKVIETKLEREVSDFEFASYLMYPKVFTDFALASDTYGPVSVLPTPAYFYGLGDGEELFADIERGKTLVIVNQAMS
ATDSQGMVTIFFELNGQPRRIKVPDRAHGATGAAVRRKAEPGNAVHVGAPMPGVISRVFVSSGQAVSAGDVLVSIEAMKM
ETALHAEKDGTIAEVLVKAGDQIDAKDLLVVYGG
>Mature_1153_residues
PISKILVANRSEIAIRVFRAANELGIKTVAIWAEEDKLALHRFKADESYQVGRGPHLARDLGPIESYLSIDEVIRVAKLS
GADAIHPGYGLLSESPEFVDACNKAGIIFIGPRADTMRQLGNKVAARNLAISVGVPVVPATEPLPDDMAVVAKMAKEIGY
PVMLKASWGGGGRGMRAIRDPKDLAREVTEAKREAMAAFGKDEVYLEKLVERARHVESQVLGDTHGNVVHLFERDCSIQR
RNQKVVERAPAPYLSEAQRQELAAYSLKIAAATNYVGAGTVEYLMDADTGKFYFIEVNPRIQVEHTVTEVVTGIDIVKAQ
IHILDGAAIGTPESGVPAQADIRLNGHALQCRITTEDPEHNFIPDYGRITAYRSASGFGIRLDGGTSYSGAIITRFYDPL
LVKVTAWAPNPSEAISRMDRALREFRIRGVATNLTFLEAIIGHPKFRDNSYTTRFIDTTPELFQQVKRQDRATKLLTYLA
DVTVNGHPEAKDRPRPLDNAAQPVVPYGNGNGVKDGTKQLLDTLGPKKFGEWMRNEKRVLLTDTTMRDGHQSLLATRMRT
YDIARIAGTYAHALPNLLSLECWGGATFDVSMRFLTEDPWERLALIREGAPNLLLQMLLRGANGVGYTNYPDNVVKYFVR
QAARGGIDLFRVFDCLNWVENMRVSMDAIAEENKLCEAAICYTGDILNSARPKYDLKYYTDLAVELEKAGAHIIALKDMA
GLLKPAAAKVLFKALREATSLPIHFHTHDTSGIAAATVLAAVDAGVDAVDAAMDALSGNTSQPCLGSIVEALRGTERDPG
LDPEWIRRVSFYWEAVRNQYAAFESDLKGPASEVYLHEMPGGQFTNLKEQARSLGLETRWHRVAQAYADANQMFGDIVKV
TPSSKVVGDMALMMVSQDLTVADVVSPDKEVSFPESVVSMLKGDLGQPPSGWPEALQKKALKGDKPYTVRPGSLLKEADL
DAERKVIETKLEREVSDFEFASYLMYPKVFTDFALASDTYGPVSVLPTPAYFYGLGDGEELFADIERGKTLVIVNQAMSA
TDSQGMVTIFFELNGQPRRIKVPDRAHGATGAAVRRKAEPGNAVHVGAPMPGVISRVFVSSGQAVSAGDVLVSIEAMKME
TALHAEKDGTIAEVLVKAGDQIDAKDLLVVYGG

Specific function: Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second, leading to oxaloacetate production. Fulfills an anaplerotic functi

COG id: COG1038

COG function: function code C; Pyruvate carboxylase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 carboxyltransferase domain [H]

Homologues:

Organism=Homo sapiens, GI106049528, Length=1155, Percent_Identity=47.5324675324675, Blast_Score=1016, Evalue=0.0,
Organism=Homo sapiens, GI106049295, Length=1155, Percent_Identity=47.5324675324675, Blast_Score=1016, Evalue=0.0,
Organism=Homo sapiens, GI106049292, Length=1155, Percent_Identity=47.5324675324675, Blast_Score=1016, Evalue=0.0,
Organism=Homo sapiens, GI116805327, Length=466, Percent_Identity=42.0600858369099, Blast_Score=384, Evalue=1e-106,
Organism=Homo sapiens, GI65506442, Length=464, Percent_Identity=40.5172413793103, Blast_Score=338, Evalue=2e-92,
Organism=Homo sapiens, GI295821183, Length=464, Percent_Identity=40.5172413793103, Blast_Score=337, Evalue=3e-92,
Organism=Homo sapiens, GI189095269, Length=464, Percent_Identity=40.5172413793103, Blast_Score=337, Evalue=3e-92,
Organism=Homo sapiens, GI38679960, Length=553, Percent_Identity=30.0180831826401, Blast_Score=226, Evalue=1e-58,
Organism=Homo sapiens, GI38679977, Length=553, Percent_Identity=30.0180831826401, Blast_Score=226, Evalue=1e-58,
Organism=Homo sapiens, GI38679967, Length=553, Percent_Identity=30.0180831826401, Blast_Score=226, Evalue=1e-58,
Organism=Homo sapiens, GI38679974, Length=553, Percent_Identity=30.0180831826401, Blast_Score=226, Evalue=1e-58,
Organism=Homo sapiens, GI38679971, Length=553, Percent_Identity=30.0180831826401, Blast_Score=226, Evalue=1e-58,
Organism=Homo sapiens, GI134142062, Length=517, Percent_Identity=30.7543520309478, Blast_Score=224, Evalue=3e-58,
Organism=Escherichia coli, GI1789654, Length=457, Percent_Identity=43.9824945295405, Blast_Score=354, Evalue=1e-98,
Organism=Caenorhabditis elegans, GI17562816, Length=1158, Percent_Identity=48.8773747841105, Blast_Score=1041, Evalue=0.0,
Organism=Caenorhabditis elegans, GI71987519, Length=467, Percent_Identity=43.4689507494647, Blast_Score=364, Evalue=1e-100,
Organism=Caenorhabditis elegans, GI17567343, Length=464, Percent_Identity=39.8706896551724, Blast_Score=331, Evalue=1e-90,
Organism=Caenorhabditis elegans, GI71997168, Length=522, Percent_Identity=29.6934865900383, Blast_Score=206, Evalue=6e-53,
Organism=Caenorhabditis elegans, GI133931226, Length=503, Percent_Identity=29.8210735586481, Blast_Score=206, Evalue=6e-53,
Organism=Caenorhabditis elegans, GI71997163, Length=522, Percent_Identity=29.6934865900383, Blast_Score=206, Evalue=8e-53,
Organism=Saccharomyces cerevisiae, GI6319695, Length=1160, Percent_Identity=46.6379310344828, Blast_Score=1011, Evalue=0.0,
Organism=Saccharomyces cerevisiae, GI6321376, Length=1160, Percent_Identity=47.2413793103448, Blast_Score=1004, Evalue=0.0,
Organism=Saccharomyces cerevisiae, GI6319685, Length=454, Percent_Identity=38.3259911894273, Blast_Score=309, Evalue=1e-84,
Organism=Saccharomyces cerevisiae, GI6324343, Length=526, Percent_Identity=31.3688212927757, Blast_Score=229, Evalue=3e-60,
Organism=Saccharomyces cerevisiae, GI6323863, Length=443, Percent_Identity=32.7313769751693, Blast_Score=218, Evalue=5e-57,
Organism=Drosophila melanogaster, GI24652212, Length=1156, Percent_Identity=47.5778546712803, Blast_Score=1013, Evalue=0.0,
Organism=Drosophila melanogaster, GI24652210, Length=1156, Percent_Identity=47.5778546712803, Blast_Score=1013, Evalue=0.0,
Organism=Drosophila melanogaster, GI24652214, Length=1156, Percent_Identity=47.5778546712803, Blast_Score=1013, Evalue=0.0,
Organism=Drosophila melanogaster, GI19921944, Length=1156, Percent_Identity=47.5778546712803, Blast_Score=1013, Evalue=0.0,
Organism=Drosophila melanogaster, GI24652216, Length=1156, Percent_Identity=47.5778546712803, Blast_Score=1013, Evalue=0.0,
Organism=Drosophila melanogaster, GI281363050, Length=1170, Percent_Identity=46.9230769230769, Blast_Score=1009, Evalue=0.0,
Organism=Drosophila melanogaster, GI24652224, Length=1170, Percent_Identity=46.9230769230769, Blast_Score=1009, Evalue=0.0,
Organism=Drosophila melanogaster, GI24652222, Length=1170, Percent_Identity=46.9230769230769, Blast_Score=1009, Evalue=0.0,
Organism=Drosophila melanogaster, GI24652220, Length=1170, Percent_Identity=46.9230769230769, Blast_Score=1009, Evalue=0.0,
Organism=Drosophila melanogaster, GI24652218, Length=1170, Percent_Identity=46.9230769230769, Blast_Score=1009, Evalue=0.0,
Organism=Drosophila melanogaster, GI24651757, Length=459, Percent_Identity=41.1764705882353, Blast_Score=361, Evalue=1e-99,
Organism=Drosophila melanogaster, GI24651759, Length=420, Percent_Identity=40, Blast_Score=317, Evalue=4e-86,
Organism=Drosophila melanogaster, GI24586458, Length=526, Percent_Identity=29.467680608365, Blast_Score=213, Evalue=6e-55,
Organism=Drosophila melanogaster, GI161076409, Length=526, Percent_Identity=29.467680608365, Blast_Score=213, Evalue=8e-55,
Organism=Drosophila melanogaster, GI161076407, Length=526, Percent_Identity=29.467680608365, Blast_Score=213, Evalue=8e-55,
Organism=Drosophila melanogaster, GI24586460, Length=526, Percent_Identity=29.467680608365, Blast_Score=213, Evalue=8e-55,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013785
- InterPro:   IPR011761
- InterPro:   IPR013815
- InterPro:   IPR013816
- InterPro:   IPR011764
- InterPro:   IPR005482
- InterPro:   IPR000089
- InterPro:   IPR005479
- InterPro:   IPR005481
- InterPro:   IPR003379
- InterPro:   IPR013817
- InterPro:   IPR016185
- InterPro:   IPR000891
- InterPro:   IPR005930
- InterPro:   IPR011054
- InterPro:   IPR011053 [H]

Pfam domain/function: PF02785 Biotin_carb_C; PF00364 Biotin_lipoyl; PF00289 CPSase_L_chain; PF02786 CPSase_L_D2; PF00682 HMGL-like; PF02436 PYC_OADA [H]

EC number: =6.4.1.1 [H]

Molecular weight: Translated: 126239; Mature: 126107

Theoretical pI: Translated: 6.15; Mature: 6.15

Prosite motif: PS50975 ATP_GRASP ; PS00866 CPSASE_1 ; PS00867 CPSASE_2 ; PS50979 BC ; PS50991 PYR_CT ; PS50968 BIOTINYL_LIPOYL ; PS00188 BIOTIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPISKILVANRSEIAIRVFRAANELGIKTVAIWAEEDKLALHRFKADESYQVGRGPHLAR
CCCHHEEECCCCHHEEHEEHHHHHCCCEEEEEEECCCCHHHHHCCCCCCCCCCCCCCHHH
DLGPIESYLSIDEVIRVAKLSGADAIHPGYGLLSESPEFVDACNKAGIIFIGPRADTMRQ
HHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCHHHHHHCCCCEEEECCCHHHHHH
LGNKVAARNLAISVGVPVVPATEPLPDDMAVVAKMAKEIGYPVMLKASWGGGGRGMRAIR
HHHHHHHHHEEEEECCCCCCCCCCCCCHHHHHHHHHHHCCCCEEEEECCCCCCCCCCCCC
DPKDLAREVTEAKREAMAAFGKDEVYLEKLVERARHVESQVLGDTHGNVVHLFERDCSIQ
CHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCCCCCCEEEEECCCCCHH
RRNQKVVERAPAPYLSEAQRQELAAYSLKIAAATNYVGAGTVEYLMDADTGKFYFIEVNP
HHHHHHHHHCCCCHHHHHHHHHHHHHHEEEEEECCCCCCCHHHHHEECCCCEEEEEEECC
RIQVEHTVTEVVTGIDIVKAQIHILDGAAIGTPESGVPAQADIRLNGHALQCRITTEDPE
EEEEHHHHHHHHHHHHHEEEEEEEEECCCCCCCCCCCCCEEEEEECCEEEEEEEECCCCC
HNFIPDYGRITAYRSASGFGIRLDGGTSYSGAIITRFYDPLLVKVTAWAPNPSEAISRMD
CCCCCCCCCEEEEECCCCCEEEECCCCCCCCEEHEECCCCEEEEEEECCCCHHHHHHHHH
RALREFRIRGVATNLTFLEAIIGHPKFRDNSYTTRFIDTTPELFQQVKRQDRATKLLTYL
HHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEECCCHHHHHHHHHHHHHHHHHHHH
ADVTVNGHPEAKDRPRPLDNAAQPVVPYGNGNGVKDGTKQLLDTLGPKKFGEWMRNEKRV
HHCEECCCCCCCCCCCCCCCCCCCEEECCCCCCCCHHHHHHHHHCCHHHHHHHHCCCCEE
LLTDTTMRDGHQSLLATRMRTYDIARIAGTYAHALPNLLSLECWGGATFDVSMRFLTEDP
EEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCEEEEEEEECCCCH
WERLALIREGAPNLLLQMLLRGANGVGYTNYPDNVVKYFVRQAARGGIDLFRVFDCLNWV
HHHHHHHHCCCHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHH
ENMRVSMDAIAEENKLCEAAICYTGDILNSARPKYDLKYYTDLAVELEKAGAHIIALKDM
HHHHHHHHHHHHHCCHHHHHHHEEHHHHHCCCCCCCEEEHHHHHHHHHHCCCEEEEEHHH
AGLLKPAAAKVLFKALREATSLPIHFHTHDTSGIAAATVLAAVDAGVDAVDAAMDALSGN
HHHHHHHHHHHHHHHHHHHHCCCEEEECCCCCCHHHHHHHHHHHCCCHHHHHHHHHHCCC
TSQPCLGSIVEALRGTERDPGLDPEWIRRVSFYWEAVRNQYAAFESDLKGPASEVYLHEM
CCCCHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHEEEEEC
PGGQFTNLKEQARSLGLETRWHRVAQAYADANQMFGDIVKVTPSSKVVGDMALMMVSQDL
CCCCCCCHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHEEECCCCHHHHHHHHHHHHCCC
TVADVVSPDKEVSFPESVVSMLKGDLGQPPSGWPEALQKKALKGDKPYTVRPGSLLKEAD
CEEECCCCCCCCCCHHHHHHHHHCCCCCCCCCCHHHHHHHHHCCCCCEEECCCCHHHHCC
LDAERKVIETKLEREVSDFEFASYLMYPKVFTDFALASDTYGPVSVLPTPAYFYGLGDGE
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEECCCCCEEEECCCHH
ELFADIERGKTLVIVNQAMSATDSQGMVTIFFELNGQPRRIKVPDRAHGATGAAVRRKAE
HHHHHHHCCCEEEEEECCCCCCCCCCEEEEEEEECCCCCEEECCCCCCCCCCHHHHCCCC
PGNAVHVGAPMPGVISRVFVSSGQAVSAGDVLVSIEAMKMETALHAEKDGTIAEVLVKAG
CCCEEEECCCCHHHHHHHHHCCCCEEECCCEEEEEEHHHHHHHHHCCCCCHHHHHHHHCC
DQIDAKDLLVVYGG
CCCCCCCEEEEECC
>Mature Secondary Structure 
PISKILVANRSEIAIRVFRAANELGIKTVAIWAEEDKLALHRFKADESYQVGRGPHLAR
CCHHEEECCCCHHEEHEEHHHHHCCCEEEEEEECCCCHHHHHCCCCCCCCCCCCCCHHH
DLGPIESYLSIDEVIRVAKLSGADAIHPGYGLLSESPEFVDACNKAGIIFIGPRADTMRQ
HHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCHHHHHHCCCCEEEECCCHHHHHH
LGNKVAARNLAISVGVPVVPATEPLPDDMAVVAKMAKEIGYPVMLKASWGGGGRGMRAIR
HHHHHHHHHEEEEECCCCCCCCCCCCCHHHHHHHHHHHCCCCEEEEECCCCCCCCCCCCC
DPKDLAREVTEAKREAMAAFGKDEVYLEKLVERARHVESQVLGDTHGNVVHLFERDCSIQ
CHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCCCCCCEEEEECCCCCHH
RRNQKVVERAPAPYLSEAQRQELAAYSLKIAAATNYVGAGTVEYLMDADTGKFYFIEVNP
HHHHHHHHHCCCCHHHHHHHHHHHHHHEEEEEECCCCCCCHHHHHEECCCCEEEEEEECC
RIQVEHTVTEVVTGIDIVKAQIHILDGAAIGTPESGVPAQADIRLNGHALQCRITTEDPE
EEEEHHHHHHHHHHHHHEEEEEEEEECCCCCCCCCCCCCEEEEEECCEEEEEEEECCCCC
HNFIPDYGRITAYRSASGFGIRLDGGTSYSGAIITRFYDPLLVKVTAWAPNPSEAISRMD
CCCCCCCCCEEEEECCCCCEEEECCCCCCCCEEHEECCCCEEEEEEECCCCHHHHHHHHH
RALREFRIRGVATNLTFLEAIIGHPKFRDNSYTTRFIDTTPELFQQVKRQDRATKLLTYL
HHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEECCCHHHHHHHHHHHHHHHHHHHH
ADVTVNGHPEAKDRPRPLDNAAQPVVPYGNGNGVKDGTKQLLDTLGPKKFGEWMRNEKRV
HHCEECCCCCCCCCCCCCCCCCCCEEECCCCCCCCHHHHHHHHHCCHHHHHHHHCCCCEE
LLTDTTMRDGHQSLLATRMRTYDIARIAGTYAHALPNLLSLECWGGATFDVSMRFLTEDP
EEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCEEEEEEEECCCCH
WERLALIREGAPNLLLQMLLRGANGVGYTNYPDNVVKYFVRQAARGGIDLFRVFDCLNWV
HHHHHHHHCCCHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHH
ENMRVSMDAIAEENKLCEAAICYTGDILNSARPKYDLKYYTDLAVELEKAGAHIIALKDM
HHHHHHHHHHHHHCCHHHHHHHEEHHHHHCCCCCCCEEEHHHHHHHHHHCCCEEEEEHHH
AGLLKPAAAKVLFKALREATSLPIHFHTHDTSGIAAATVLAAVDAGVDAVDAAMDALSGN
HHHHHHHHHHHHHHHHHHHHCCCEEEECCCCCCHHHHHHHHHHHCCCHHHHHHHHHHCCC
TSQPCLGSIVEALRGTERDPGLDPEWIRRVSFYWEAVRNQYAAFESDLKGPASEVYLHEM
CCCCHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHEEEEEC
PGGQFTNLKEQARSLGLETRWHRVAQAYADANQMFGDIVKVTPSSKVVGDMALMMVSQDL
CCCCCCCHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHEEECCCCHHHHHHHHHHHHCCC
TVADVVSPDKEVSFPESVVSMLKGDLGQPPSGWPEALQKKALKGDKPYTVRPGSLLKEAD
CEEECCCCCCCCCCHHHHHHHHHCCCCCCCCCCHHHHHHHHHCCCCCEEECCCCHHHHCC
LDAERKVIETKLEREVSDFEFASYLMYPKVFTDFALASDTYGPVSVLPTPAYFYGLGDGE
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEECCCCCEEEECCCHH
ELFADIERGKTLVIVNQAMSATDSQGMVTIFFELNGQPRRIKVPDRAHGATGAAVRRKAE
HHHHHHHCCCEEEEEECCCCCCCCCCEEEEEEEECCCCCEEECCCCCCCCCCHHHHCCCC
PGNAVHVGAPMPGVISRVFVSSGQAVSAGDVLVSIEAMKMETALHAEKDGTIAEVLVKAG
CCCEEEECCCCHHHHHHHHHCCCCEEECCCEEEEEEHHHHHHHHHCCCCCHHHHHHHHCC
DQIDAKDLLVVYGG
CCCCCCCEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]