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The map label for this gene is tcyB [H]

Identifier: 209551407

GI number: 209551407

Start: 3968894

End: 3969574

Strand: Direct

Name: tcyB [H]

Synonym: Rleg2_3836

Alternate gene names: 209551407

Gene position: 3968894-3969574 (Clockwise)

Preceding gene: 209551406

Following gene: 209551408

Centisome position: 87.46

GC content: 64.61

Gene sequence:

>681_bases
TTGCCGCACTGGCTTCAACTGATGGCGGAATCGCTCCCCTCGCTTCTCTGGGCGGGACTGATCTTCACCATCCCCCTCAC
GCTGCTGTCCTTCGCCTTCGGCCTGATCCTCGGGCTGATCACCGCGATTGCCCGCCTGTTCGGTCCGGGGCCAGTCGCGG
CTATCGCTCGTTTCTATGTCTGGGTCATCCGCGGCACGCCGCTGCTCGTCCAGCTCTTCGTGATTTTCTACGGCCTGCCG
AGCATCGGTATCCTGCTCGATGCCTTTCCCGCCGCCCTCATCGGTTTCACCCTGAATATCGGCGCCTACAGCTCCGAGAT
CATCCGCGCCGTCATCTCCTCGGTGCCCAAGGGCCAGTGGGAGGCCGCCTATTCGATCGGCATGAGCTGGCGCCAGGCGA
TGAGCCGCACCATCCTGCCGCAGGCCGCCCGCGTCGCCGTGCCGCCGCTGTCGAACACCTTCATCTCGCTGGTCAAGGAT
ACCTCGCTTGCCGCCGCCATCACCGTGCCGGAACTCTTCCAGGCGGCGCAGCGCATCGTCGCCACCACCTATGAGCCGCT
GATCCTCTATATCGAGGCGGCGCTGCTCTATCTCGTGCTGAGCTCCGTCCTCTCGCAGCTGCAGGTGCGGCTGGAACGCC
GTTTCGCGCGTTATGGCGGCATGCTGGAGGCCAATGCATGA

Upstream 100 bases:

>100_bases
ATGCCACGCGGGAGCCGGATTAAGTCCCTCCCCCTTGTGGGGAGGGGTTGGGGAGGGGTATTCCGAAGTATCACTGCTCA
ATCCATGAGAGGGAAGACCC

Downstream 100 bases:

>100_bases
TCGAGCTTTCCAACATCGAAAAGCGCTTCGGCGACGCCGTCATCCTGAAGGATATCAGCATCCGCATTCCCGAAGGCAGC
GTCACCGCGCTGGTCGGCCC

Product: polar amino acid ABC transporter inner membrane subunit

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 226; Mature: 225

Protein sequence:

>226_residues
MPHWLQLMAESLPSLLWAGLIFTIPLTLLSFAFGLILGLITAIARLFGPGPVAAIARFYVWVIRGTPLLVQLFVIFYGLP
SIGILLDAFPAALIGFTLNIGAYSSEIIRAVISSVPKGQWEAAYSIGMSWRQAMSRTILPQAARVAVPPLSNTFISLVKD
TSLAAAITVPELFQAAQRIVATTYEPLILYIEAALLYLVLSSVLSQLQVRLERRFARYGGMLEANA

Sequences:

>Translated_226_residues
MPHWLQLMAESLPSLLWAGLIFTIPLTLLSFAFGLILGLITAIARLFGPGPVAAIARFYVWVIRGTPLLVQLFVIFYGLP
SIGILLDAFPAALIGFTLNIGAYSSEIIRAVISSVPKGQWEAAYSIGMSWRQAMSRTILPQAARVAVPPLSNTFISLVKD
TSLAAAITVPELFQAAQRIVATTYEPLILYIEAALLYLVLSSVLSQLQVRLERRFARYGGMLEANA
>Mature_225_residues
PHWLQLMAESLPSLLWAGLIFTIPLTLLSFAFGLILGLITAIARLFGPGPVAAIARFYVWVIRGTPLLVQLFVIFYGLPS
IGILLDAFPAALIGFTLNIGAYSSEIIRAVISSVPKGQWEAAYSIGMSWRQAMSRTILPQAARVAVPPLSNTFISLVKDT
SLAAAITVPELFQAAQRIVATTYEPLILYIEAALLYLVLSSVLSQLQVRLERRFARYGGMLEANA

Specific function: Part of the ABC transporter complex tcyABC involved in L-cystine import. Probably responsible for the translocation of the substrate across the membrane (Probable) [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transmembrane type-1 domain [H]

Homologues:

Organism=Escherichia coli, GI1788226, Length=217, Percent_Identity=54.8387096774194, Blast_Score=219, Evalue=1e-58,
Organism=Escherichia coli, GI1787030, Length=202, Percent_Identity=38.6138613861386, Blast_Score=126, Evalue=1e-30,
Organism=Escherichia coli, GI1788645, Length=230, Percent_Identity=35.2173913043478, Blast_Score=117, Evalue=8e-28,
Organism=Escherichia coli, GI1787086, Length=218, Percent_Identity=32.5688073394495, Blast_Score=101, Evalue=4e-23,
Organism=Escherichia coli, GI87082239, Length=215, Percent_Identity=32.5581395348837, Blast_Score=97, Evalue=9e-22,
Organism=Escherichia coli, GI1786873, Length=216, Percent_Identity=35.1851851851852, Blast_Score=97, Evalue=1e-21,
Organism=Escherichia coli, GI1788646, Length=220, Percent_Identity=30, Blast_Score=95, Evalue=4e-21,
Organism=Escherichia coli, GI1787087, Length=235, Percent_Identity=30.2127659574468, Blast_Score=89, Evalue=3e-19,
Organism=Escherichia coli, GI1786874, Length=219, Percent_Identity=25.5707762557078, Blast_Score=82, Evalue=4e-17,
Organism=Escherichia coli, GI48994930, Length=134, Percent_Identity=34.3283582089552, Blast_Score=73, Evalue=2e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010065
- InterPro:   IPR000515 [H]

Pfam domain/function: PF00528 BPD_transp_1 [H]

EC number: NA

Molecular weight: Translated: 24637; Mature: 24505

Theoretical pI: Translated: 9.84; Mature: 9.84

Prosite motif: PS50928 ABC_TM1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPHWLQLMAESLPSLLWAGLIFTIPLTLLSFAFGLILGLITAIARLFGPGPVAAIARFYV
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHH
WVIRGTPLLVQLFVIFYGLPSIGILLDAFPAALIGFTLNIGAYSSEIIRAVISSVPKGQW
HHHCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCCCCH
EAAYSIGMSWRQAMSRTILPQAARVAVPPLSNTFISLVKDTSLAAAITVPELFQAAQRIV
HHHHHHHHHHHHHHHHHHCCHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ATTYEPLILYIEAALLYLVLSSVLSQLQVRLERRFARYGGMLEANA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCC
>Mature Secondary Structure 
PHWLQLMAESLPSLLWAGLIFTIPLTLLSFAFGLILGLITAIARLFGPGPVAAIARFYV
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHH
WVIRGTPLLVQLFVIFYGLPSIGILLDAFPAALIGFTLNIGAYSSEIIRAVISSVPKGQW
HHHCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCCCCH
EAAYSIGMSWRQAMSRTILPQAARVAVPPLSNTFISLVKDTSLAAAITVPELFQAAQRIV
HHHHHHHHHHHHHHHHHHCCHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ATTYEPLILYIEAALLYLVLSSVLSQLQVRLERRFARYGGMLEANA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 7551042; 8969502; 9384377 [H]