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The map label for this gene is tcyA [H]

Identifier: 209551406

GI number: 209551406

Start: 3967906

End: 3968679

Strand: Direct

Name: tcyA [H]

Synonym: Rleg2_3835

Alternate gene names: 209551406

Gene position: 3967906-3968679 (Clockwise)

Preceding gene: 209551405

Following gene: 209551407

Centisome position: 87.44

GC content: 60.21

Gene sequence:

>774_bases
ATGAACTGGTTGAAAACCGTCGCCGCTGCCGCCCTCATTCAGGCTGCCGCCCTCCTGCCCGCCCATGCCGGCGAAAACCT
TGCCGCCATCAAATCGGCCGGCGTCTTCAAGATCGGCACCGAAGGCACCTATGCGCCCTTCACCTATCATGACGAAAGCG
GCAAGCTCGTCGGCTTCGACGTCGAGATCGGTGAAGCGATTGCCGCCAAGCTCGGCGTCAAGGCCGAGTTCGTCGAAGGC
AAGTGGGATGGCCTGATCGCCGGCCTCGACGCCAAGCGCTACGACACCGTCATCAACCAGGTCGGCATCACCGAGGCCCG
CAAGCAGAAATATGATTTCTCCGAACCCTATATCGCCTCCAAGGCAGTGCTGATCGTCCGCGACGGCGACGACAGCATCA
AGACCTTCGCCGACTTGAAGGGCAAGAAATCCGCCCAGTCGCTGACCAGCAACTTCGGCAAGATCGCAACCGAAGCCGGC
GCCGAACTCGTCGGCACCGACGGTTTCGACCAGTCGATCCAGCTTGTGCTGACCAAGCGCGCCGACGCGACGATCAACGA
CAGCCTCTCCTTCCTCGATTTCAAGAAGCACAAGCCGGACGCGCCGGTGAAGATCGCCGCCGAGCAGGAAAATGCCGATT
ATTCCGGCGTCATCATCCGCAAGAACGAACCGGAGCTTCTTGCCGAAATCAACAAGGCGCTCGCCGACATCAAGGCCGAC
GGCACCTACAAGAAGATCGCCGACAAGTATTTCGGCCAGGACGTCTCGAAGTAA

Upstream 100 bases:

>100_bases
CAGTTGCTGCTTTTATTCGCAGTTTTTTACGCTTCCGGCGCCCTAAATTTCTGCGAACTATCCCTCATCCGATGACAACC
TCCCAAGGATGGATAAAACA

Downstream 100 bases:

>100_bases
GCTACACTCGGGAAAAAGTCCCCTCCCCAACCCCTCCCCACAAGGGGGAGGGGCTTTGGCCGGGGCACCGCCTCATCTCA
AAATAGACGTTTCGACTTGT

Product: family 3 extracellular solute-binding protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 257; Mature: 257

Protein sequence:

>257_residues
MNWLKTVAAAALIQAAALLPAHAGENLAAIKSAGVFKIGTEGTYAPFTYHDESGKLVGFDVEIGEAIAAKLGVKAEFVEG
KWDGLIAGLDAKRYDTVINQVGITEARKQKYDFSEPYIASKAVLIVRDGDDSIKTFADLKGKKSAQSLTSNFGKIATEAG
AELVGTDGFDQSIQLVLTKRADATINDSLSFLDFKKHKPDAPVKIAAEQENADYSGVIIRKNEPELLAEINKALADIKAD
GTYKKIADKYFGQDVSK

Sequences:

>Translated_257_residues
MNWLKTVAAAALIQAAALLPAHAGENLAAIKSAGVFKIGTEGTYAPFTYHDESGKLVGFDVEIGEAIAAKLGVKAEFVEG
KWDGLIAGLDAKRYDTVINQVGITEARKQKYDFSEPYIASKAVLIVRDGDDSIKTFADLKGKKSAQSLTSNFGKIATEAG
AELVGTDGFDQSIQLVLTKRADATINDSLSFLDFKKHKPDAPVKIAAEQENADYSGVIIRKNEPELLAEINKALADIKAD
GTYKKIADKYFGQDVSK
>Mature_257_residues
MNWLKTVAAAALIQAAALLPAHAGENLAAIKSAGVFKIGTEGTYAPFTYHDESGKLVGFDVEIGEAIAAKLGVKAEFVEG
KWDGLIAGLDAKRYDTVINQVGITEARKQKYDFSEPYIASKAVLIVRDGDDSIKTFADLKGKKSAQSLTSNFGKIATEAG
AELVGTDGFDQSIQLVLTKRADATINDSLSFLDFKKHKPDAPVKIAAEQENADYSGVIIRKNEPELLAEINKALADIKAD
GTYKKIADKYFGQDVSK

Specific function: Part of the ABC transporter complex tcyABC involved in L-cystine import [H]

COG id: COG0834

COG function: function code ET; ABC-type amino acid transport/signal transduction systems, periplasmic component/domain

Gene ontology:

Cell location: Cell membrane; Lipid-anchor (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the bacterial solute-binding protein 3 family [H]

Homologues:

Organism=Escherichia coli, GI1788228, Length=258, Percent_Identity=39.1472868217054, Blast_Score=165, Evalue=3e-42,
Organism=Escherichia coli, GI1787085, Length=221, Percent_Identity=31.6742081447964, Blast_Score=114, Evalue=7e-27,
Organism=Escherichia coli, GI1788648, Length=233, Percent_Identity=33.9055793991416, Blast_Score=113, Evalue=1e-26,
Organism=Escherichia coli, GI1788649, Length=229, Percent_Identity=32.7510917030568, Blast_Score=109, Evalue=2e-25,
Organism=Escherichia coli, GI1787031, Length=246, Percent_Identity=29.6747967479675, Blast_Score=92, Evalue=3e-20,
Organism=Escherichia coli, GI1787088, Length=257, Percent_Identity=28.0155642023346, Blast_Score=89, Evalue=3e-19,

Paralogues:

None

Copy number: 1920 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 1060 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 80 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001638
- InterPro:   IPR018313 [H]

Pfam domain/function: PF00497 SBP_bac_3 [H]

EC number: NA

Molecular weight: Translated: 27589; Mature: 27589

Theoretical pI: Translated: 5.46; Mature: 5.46

Prosite motif: PS01039 SBP_BACTERIAL_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
0.4 %Met     (Translated Protein)
0.4 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
0.4 %Met     (Mature Protein)
0.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNWLKTVAAAALIQAAALLPAHAGENLAAIKSAGVFKIGTEGTYAPFTYHDESGKLVGFD
CCHHHHHHHHHHHHHHHHHHCCCCCCCHHHHCCCEEEECCCCCCCCEEEECCCCCEEEEE
VEIGEAIAAKLGVKAEFVEGKWDGLIAGLDAKRYDTVINQVGITEARKQKYDFSEPYIAS
CHHHHHHHHHHCCEEEEECCCCCCEEECCCHHHHHHHHHHCCCCHHHHHCCCCCCCCCCC
KAVLIVRDGDDSIKTFADLKGKKSAQSLTSNFGKIATEAGAELVGTDGFDQSIQLVLTKR
EEEEEEECCCCHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCEEECCCCCCCCEEEEEEEC
ADATINDSLSFLDFKKHKPDAPVKIAAEQENADYSGVIIRKNEPELLAEINKALADIKAD
CCCCCCCCCHHHHHHCCCCCCCEEEEEECCCCCCCEEEEECCCCHHHHHHHHHHHHHCCC
GTYKKIADKYFGQDVSK
CHHHHHHHHHHCCCCCC
>Mature Secondary Structure
MNWLKTVAAAALIQAAALLPAHAGENLAAIKSAGVFKIGTEGTYAPFTYHDESGKLVGFD
CCHHHHHHHHHHHHHHHHHHCCCCCCCHHHHCCCEEEECCCCCCCCEEEECCCCCEEEEE
VEIGEAIAAKLGVKAEFVEGKWDGLIAGLDAKRYDTVINQVGITEARKQKYDFSEPYIAS
CHHHHHHHHHHCCEEEEECCCCCCEEECCCHHHHHHHHHHCCCCHHHHHCCCCCCCCCCC
KAVLIVRDGDDSIKTFADLKGKKSAQSLTSNFGKIATEAGAELVGTDGFDQSIQLVLTKR
EEEEEEECCCCHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCEEECCCCCCCCEEEEEEEC
ADATINDSLSFLDFKKHKPDAPVKIAAEQENADYSGVIIRKNEPELLAEINKALADIKAD
CCCCCCCCCHHHHHHCCCCCCCEEEEEECCCCCCCEEEEECCCCHHHHHHHHHHHHHCCC
GTYKKIADKYFGQDVSK
CHHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 7551042; 8969502; 9384377 [H]