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The map label for this gene is fps [H]

Identifier: 209551400

GI number: 209551400

Start: 3961287

End: 3962201

Strand: Direct

Name: fps [H]

Synonym: Rleg2_3829

Alternate gene names: 209551400

Gene position: 3961287-3962201 (Clockwise)

Preceding gene: 209551394

Following gene: 209551405

Centisome position: 87.29

GC content: 66.89

Gene sequence:

>915_bases
ATGGATGCGAACCGGGACACTTTCGAGACGAGGCTGAAGAACAACGCCCGCGAGATCGAGGCGCTGCTCGATGCATTGCT
TTTACCGAACGCCCTTTCCGACGAAATCGCCAGGCCCGAGACGCTGCGCAGCGCCATGCACTATGCCGTGCTGAACGGCG
GCAAGCGGCTGCGCCCGTTCCTGGTGGTCGAAAGCGCCGCCCTTCTCGGCGGCGATGACGAGGCCGCACGCCGCGTCGGC
GCCGCACTCGAATGCGTCCACTGTTATTCGCTCGTGCATGACGATCTGCCCGCCATGGACGACGATGATCTCCGCCGCGG
CAAACCGACTGTTCATATCAAGTTCGATGAAGCCACCGCGATCCTCGCCGGCGACAGCCTGCTGACCTACGCCTTCGACA
TCATCGCCGCGCCGGAAACGGCGCTTGCCGACACGAGCAAGGCATCGCTGGTGCTGGCGCTTGCCCGCGCCGCCGGTCTC
GGCGGCATGGCCGGCGGCCAAGCGCTCGATCTCGCGGCGGAGAAGCAGGCTCCTGATGAGGCCGGCATCATCCGCCTGCA
GGCGATGAAAACCGGCGCGCTGATCCGCTTCGCCTGCGAAGCCGGCGCCCTCATCGCGGCAAGCCCGCCGGAAGATCGGC
GCCGCCTGCGTGCTTTCGGCGAAAAGATCGGCCTTGCCTTTCAGCTCGCCGACGACATTCTCGACCTGACCTCGGACACT
GCAACCATGGGCAAGGCGACCGGCAAGGATGCGGCCCGCGGTAAGGGAACGCTCGTGGCGCTGCATGGCATCGAATGGGC
CGAGGAGCAGCTCCGCCAGCATGTCCGCGATGCCGAGGCGCTGCTGGCCCCCTACGGCGCCCGCGCCTCGACCCTGATCG
CCGCGGCGCATTTCATCGCCGACCGGAAGAGCTGA

Upstream 100 bases:

>100_bases
TAACGCCTGTAGGCCGCTTATGCCAGAGTGCGTGGCGAATCTTGCCGCGCCATCGACAATTCCGTTGCAAGCCCGGGGGC
GCTCATGCCAAACAGCGCCC

Downstream 100 bases:

>100_bases
AGCGTCACTCAGGCTGCCAGTATTTCCTTGAGAGCGGAAACCAGACGGGCGCACTCCTCGTTCGTGCCGATGCTGATGCG
CAGGAAATCCGAAATGCGCG

Product: polyprenyl synthetase

Products: NA

Alternate protein names: FPP synthase; (2E,6E)-farnesyl diphosphate synthase; Geranyltranstransferase [H]

Number of amino acids: Translated: 304; Mature: 304

Protein sequence:

>304_residues
MDANRDTFETRLKNNAREIEALLDALLLPNALSDEIARPETLRSAMHYAVLNGGKRLRPFLVVESAALLGGDDEAARRVG
AALECVHCYSLVHDDLPAMDDDDLRRGKPTVHIKFDEATAILAGDSLLTYAFDIIAAPETALADTSKASLVLALARAAGL
GGMAGGQALDLAAEKQAPDEAGIIRLQAMKTGALIRFACEAGALIAASPPEDRRRLRAFGEKIGLAFQLADDILDLTSDT
ATMGKATGKDAARGKGTLVALHGIEWAEEQLRQHVRDAEALLAPYGARASTLIAAAHFIADRKS

Sequences:

>Translated_304_residues
MDANRDTFETRLKNNAREIEALLDALLLPNALSDEIARPETLRSAMHYAVLNGGKRLRPFLVVESAALLGGDDEAARRVG
AALECVHCYSLVHDDLPAMDDDDLRRGKPTVHIKFDEATAILAGDSLLTYAFDIIAAPETALADTSKASLVLALARAAGL
GGMAGGQALDLAAEKQAPDEAGIIRLQAMKTGALIRFACEAGALIAASPPEDRRRLRAFGEKIGLAFQLADDILDLTSDT
ATMGKATGKDAARGKGTLVALHGIEWAEEQLRQHVRDAEALLAPYGARASTLIAAAHFIADRKS
>Mature_304_residues
MDANRDTFETRLKNNAREIEALLDALLLPNALSDEIARPETLRSAMHYAVLNGGKRLRPFLVVESAALLGGDDEAARRVG
AALECVHCYSLVHDDLPAMDDDDLRRGKPTVHIKFDEATAILAGDSLLTYAFDIIAAPETALADTSKASLVLALARAAGL
GGMAGGQALDLAAEKQAPDEAGIIRLQAMKTGALIRFACEAGALIAASPPEDRRRLRAFGEKIGLAFQLADDILDLTSDT
ATMGKATGKDAARGKGTLVALHGIEWAEEQLRQHVRDAEALLAPYGARASTLIAAAHFIADRKS

Specific function: Unknown

COG id: COG0142

COG function: function code H; Geranylgeranyl pyrophosphate synthase

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the FPP/GGPP synthase family [H]

Homologues:

Organism=Homo sapiens, GI50659086, Length=224, Percent_Identity=30.8035714285714, Blast_Score=88, Evalue=1e-17,
Organism=Escherichia coli, GI1786623, Length=268, Percent_Identity=48.8805970149254, Blast_Score=181, Evalue=4e-47,
Organism=Escherichia coli, GI1789578, Length=234, Percent_Identity=33.3333333333333, Blast_Score=123, Evalue=1e-29,
Organism=Caenorhabditis elegans, GI17505681, Length=261, Percent_Identity=26.0536398467433, Blast_Score=69, Evalue=4e-12,
Organism=Drosophila melanogaster, GI24651612, Length=242, Percent_Identity=31.404958677686, Blast_Score=86, Evalue=3e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000092
- InterPro:   IPR017446
- InterPro:   IPR008949 [H]

Pfam domain/function: PF00348 polyprenyl_synt [H]

EC number: =2.5.1.10 [H]

Molecular weight: Translated: 32286; Mature: 32286

Theoretical pI: Translated: 5.10; Mature: 5.10

Prosite motif: PS00723 POLYPRENYL_SYNTHET_1 ; PS00444 POLYPRENYL_SYNTHET_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDANRDTFETRLKNNAREIEALLDALLLPNALSDEIARPETLRSAMHYAVLNGGKRLRPF
CCCCHHHHHHHHHCCHHHHHHHHHHHHCCCHHHHHHCCHHHHHHHHHHHHHCCCCCCCCE
LVVESAALLGGDDEAARRVGAALECVHCYSLVHDDLPAMDDDDLRRGKPTVHIKFDEATA
EEEEHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHCCCCEEEEEECCCEE
ILAGDSLLTYAFDIIAAPETALADTSKASLVLALARAAGLGGMAGGQALDLAAEKQAPDE
EEECCHHHHHHHHHHCCCCHHHCCCCHHHHHHHHHHHCCCCCCCCCCCEEHHHHHCCCCC
AGIIRLQAMKTGALIRFACEAGALIAASPPEDRRRLRAFGEKIGLAFQLADDILDLTSDT
CCEEEEEEECCCCEEEEEECCCEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCH
ATMGKATGKDAARGKGTLVALHGIEWAEEQLRQHVRDAEALLAPYGARASTLIAAAHFIA
HHHCCCCCCCCCCCCCCEEEEECCHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHH
DRKS
CCCC
>Mature Secondary Structure
MDANRDTFETRLKNNAREIEALLDALLLPNALSDEIARPETLRSAMHYAVLNGGKRLRPF
CCCCHHHHHHHHHCCHHHHHHHHHHHHCCCHHHHHHCCHHHHHHHHHHHHHCCCCCCCCE
LVVESAALLGGDDEAARRVGAALECVHCYSLVHDDLPAMDDDDLRRGKPTVHIKFDEATA
EEEEHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHCCCCEEEEEECCCEE
ILAGDSLLTYAFDIIAAPETALADTSKASLVLALARAAGLGGMAGGQALDLAAEKQAPDE
EEECCHHHHHHHHHHCCCCHHHCCCCHHHHHHHHHHHCCCCCCCCCCCEEHHHHHCCCCC
AGIIRLQAMKTGALIRFACEAGALIAASPPEDRRRLRAFGEKIGLAFQLADDILDLTSDT
CCEEEEEEECCCCEEEEEECCCEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCH
ATMGKATGKDAARGKGTLVALHGIEWAEEQLRQHVRDAEALLAPYGARASTLIAAAHFIA
HHHCCCCCCCCCCCCCCEEEEECCHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHH
DRKS
CCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9515931 [H]