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The map label for this gene is ffh [H]

Identifier: 209551321

GI number: 209551321

Start: 3876004

End: 3877587

Strand: Direct

Name: ffh [H]

Synonym: Rleg2_3750

Alternate gene names: 209551321

Gene position: 3876004-3877587 (Clockwise)

Preceding gene: 209551314

Following gene: 209551322

Centisome position: 85.41

GC content: 65.03

Gene sequence:

>1584_bases
ATGTTTGAAAACCTCCAGGACCGTCTTGGATCCATTCTGAATGGACTGACAGGCCGTGGCGCGCTTTCGGAAGCCGATGT
TTCCGCAGCGCTGCGCGAGGTTCGCCGTGCGCTGCTGGAGGCCGACGTCGCGCTCGACGTCGTGCGTTCCTTCACCGACC
GCGTGCGCGAAAAGGCCGTTGGCGCCGAGATCCTGAAGTCGATCAAGCCCGGCCAGATGGTCGTCAAGATCGTCCATGAT
GAGCTGATCGAAATGCTGGGCGGTGAGGGCGTCGGCATCGACCTGCATGCGCCCGCCCCCGTCGTCGTTATGATGGTCGG
CCTGCAGGGCTCCGGCAAGACGACGACGTCAGCCAAGATCGCCCATCGCCTGTCGACGCGCGATAAGAAGAAAGTGCTGA
TGGCGTCGCTCGACACGCGCCGTCCGGCAGCCCAGGAGCAGCTTCGCCAGCTCGGCGCCCAGGCCAGCATCGACACGCTG
CCGATCATATCCGGCCAGTCGCCGACCGATATCGCCGCCCGCGCCGTGCAGGCGGCAAGACTTGGCGGCCATGACGTCGT
CATCCTCGACACCGCCGGCCGCACCCATATCGACGAGCCCTTGATGGTCGAGATGGCCGACATCAAGAAGCGCTCGAACC
CGCATGAAATCCTGCTGGTCGCCGACAGCTTGACCGGTCAGGACGCCGTCAACCTCGCCCGCAACTTCGACGAACGCGTC
GGCATCACCGGTCTGGTGCTGACCCGCATGGACGGCGATGGCCGCGGCGGTGCCGCCCTTTCGATGCGCGCCGTCACCGG
CAAGCCGATCAAGCTGATCGGTGTCGGCGAGAAGATGAGCGAGCTCGAGGAGTTCCATCCCCGCCGCATCGCCGACCGCA
TCCTCGGCATGGGCGACATCGTCTCGCTCGTCGAGCGCGCCGCCGAGAATATCGACGCCGAGAAGGCGGCCGCCATGGCC
GCCAAGATGGCCAAGGGCAAATTCGACCTCGACGACCTCGCCGACCAGCTGCGTCAGATGCAGAAGATGGGCGGCATGGG
CGGCATCATGGGAATGATGCCCGGCATGGCCGGCATGAAGGACAAGATGGCCGCAGCCGGCCTCGACGACAGGCTTTTCG
GCCGTCAGATCGCCATCATCCAGTCGATGACCAAGGCCGAGCGCGCCAATCCCGACCTGCTCAAGCATTCGCGCAAGAAG
CGCATCGCCGCCGGCTCCGGCACCGATGCCGCCGCCATCAACAAACTTCTGAAGATGCACCGCCAGATGGCCGACATGAT
GAAGATGATGGGCGGCAAGGGCAAAGGCGGCATGATGAAGCAGATGATGGGCGGCCTTGCCGGCAAGATGGGGCTGGGGG
GCCTCGGCGGCATGGGCGGCATGCCTGATCTCTCGAATATGGACCCGAAGCAGCTTGAAGCGCTGCAGAAGCAGGCGGAA
GCCGCGGGTTTGGGAAAACCGGGTGGGGGTATGCCCGGTCTAGGCGGAGGCTTGCCGGGCGGATTGCCCGGTCTTGGCGG
CGCAAAGCTGCCGGGCCTCGGTGGTGGTTTCCCGGGATTGCCCGGATTGCCGAAGAAGAAGTGA

Upstream 100 bases:

>100_bases
CCCTCGGGTGCTTTTTGGCTTTGCGTCTTGTTTTCGTCAAGGAAAAGCACGACGTTTCCGGGCAGATCGAACCCGCCCGA
AACGTATCAAGGAAGAGCCG

Downstream 100 bases:

>100_bases
AAGGATCGCTTGCCCCATGATTGATCCAAACGTCAAAGCCCAGCTCGCGAGCTATCGTCAGTCGATCGACAATATCGATG
CCGCTCTCGTGCACATGCTG

Product: signal recognition particle protein

Products: NA

Alternate protein names: Fifty-four homolog [H]

Number of amino acids: Translated: 527; Mature: 527

Protein sequence:

>527_residues
MFENLQDRLGSILNGLTGRGALSEADVSAALREVRRALLEADVALDVVRSFTDRVREKAVGAEILKSIKPGQMVVKIVHD
ELIEMLGGEGVGIDLHAPAPVVVMMVGLQGSGKTTTSAKIAHRLSTRDKKKVLMASLDTRRPAAQEQLRQLGAQASIDTL
PIISGQSPTDIAARAVQAARLGGHDVVILDTAGRTHIDEPLMVEMADIKKRSNPHEILLVADSLTGQDAVNLARNFDERV
GITGLVLTRMDGDGRGGAALSMRAVTGKPIKLIGVGEKMSELEEFHPRRIADRILGMGDIVSLVERAAENIDAEKAAAMA
AKMAKGKFDLDDLADQLRQMQKMGGMGGIMGMMPGMAGMKDKMAAAGLDDRLFGRQIAIIQSMTKAERANPDLLKHSRKK
RIAAGSGTDAAAINKLLKMHRQMADMMKMMGGKGKGGMMKQMMGGLAGKMGLGGLGGMGGMPDLSNMDPKQLEALQKQAE
AAGLGKPGGGMPGLGGGLPGGLPGLGGAKLPGLGGGFPGLPGLPKKK

Sequences:

>Translated_527_residues
MFENLQDRLGSILNGLTGRGALSEADVSAALREVRRALLEADVALDVVRSFTDRVREKAVGAEILKSIKPGQMVVKIVHD
ELIEMLGGEGVGIDLHAPAPVVVMMVGLQGSGKTTTSAKIAHRLSTRDKKKVLMASLDTRRPAAQEQLRQLGAQASIDTL
PIISGQSPTDIAARAVQAARLGGHDVVILDTAGRTHIDEPLMVEMADIKKRSNPHEILLVADSLTGQDAVNLARNFDERV
GITGLVLTRMDGDGRGGAALSMRAVTGKPIKLIGVGEKMSELEEFHPRRIADRILGMGDIVSLVERAAENIDAEKAAAMA
AKMAKGKFDLDDLADQLRQMQKMGGMGGIMGMMPGMAGMKDKMAAAGLDDRLFGRQIAIIQSMTKAERANPDLLKHSRKK
RIAAGSGTDAAAINKLLKMHRQMADMMKMMGGKGKGGMMKQMMGGLAGKMGLGGLGGMGGMPDLSNMDPKQLEALQKQAE
AAGLGKPGGGMPGLGGGLPGGLPGLGGAKLPGLGGGFPGLPGLPKKK
>Mature_527_residues
MFENLQDRLGSILNGLTGRGALSEADVSAALREVRRALLEADVALDVVRSFTDRVREKAVGAEILKSIKPGQMVVKIVHD
ELIEMLGGEGVGIDLHAPAPVVVMMVGLQGSGKTTTSAKIAHRLSTRDKKKVLMASLDTRRPAAQEQLRQLGAQASIDTL
PIISGQSPTDIAARAVQAARLGGHDVVILDTAGRTHIDEPLMVEMADIKKRSNPHEILLVADSLTGQDAVNLARNFDERV
GITGLVLTRMDGDGRGGAALSMRAVTGKPIKLIGVGEKMSELEEFHPRRIADRILGMGDIVSLVERAAENIDAEKAAAMA
AKMAKGKFDLDDLADQLRQMQKMGGMGGIMGMMPGMAGMKDKMAAAGLDDRLFGRQIAIIQSMTKAERANPDLLKHSRKK
RIAAGSGTDAAAINKLLKMHRQMADMMKMMGGKGKGGMMKQMMGGLAGKMGLGGLGGMGGMPDLSNMDPKQLEALQKQAE
AAGLGKPGGGMPGLGGGLPGGLPGLGGAKLPGLGGGFPGLPGLPKKK

Specific function: Necessary for efficient export of extracytoplasmic proteins. Binds to the signal sequence when it emerges from the ribosomes [H]

COG id: COG0541

COG function: function code U; Signal recognition particle GTPase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the GTP-binding SRP family [H]

Homologues:

Organism=Homo sapiens, GI4507215, Length=503, Percent_Identity=30.6163021868787, Blast_Score=207, Evalue=3e-53,
Organism=Homo sapiens, GI226371618, Length=439, Percent_Identity=30.9794988610478, Blast_Score=181, Evalue=1e-45,
Organism=Homo sapiens, GI295424842, Length=311, Percent_Identity=28.9389067524116, Blast_Score=112, Evalue=1e-24,
Organism=Homo sapiens, GI23308697, Length=311, Percent_Identity=28.9389067524116, Blast_Score=112, Evalue=1e-24,
Organism=Homo sapiens, GI89061728, Length=142, Percent_Identity=33.0985915492958, Blast_Score=94, Evalue=4e-19,
Organism=Escherichia coli, GI1788963, Length=429, Percent_Identity=51.5151515151515, Blast_Score=422, Evalue=1e-119,
Organism=Escherichia coli, GI1789874, Length=251, Percent_Identity=35.0597609561753, Blast_Score=133, Evalue=2e-32,
Organism=Caenorhabditis elegans, GI17539958, Length=472, Percent_Identity=29.6610169491525, Blast_Score=208, Evalue=6e-54,
Organism=Caenorhabditis elegans, GI193206261, Length=298, Percent_Identity=31.5436241610738, Blast_Score=112, Evalue=3e-25,
Organism=Saccharomyces cerevisiae, GI6325345, Length=494, Percent_Identity=30.9716599190283, Blast_Score=214, Evalue=2e-56,
Organism=Saccharomyces cerevisiae, GI6320498, Length=317, Percent_Identity=25.8675078864353, Blast_Score=100, Evalue=9e-22,
Organism=Drosophila melanogaster, GI17647949, Length=481, Percent_Identity=29.3139293139293, Blast_Score=192, Evalue=7e-49,
Organism=Drosophila melanogaster, GI24641198, Length=319, Percent_Identity=29.153605015674, Blast_Score=111, Evalue=1e-24,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR000897
- InterPro:   IPR013822
- InterPro:   IPR004780
- InterPro:   IPR004125 [H]

Pfam domain/function: PF00448 SRP54; PF02881 SRP54_N; PF02978 SRP_SPB [H]

EC number: NA

Molecular weight: Translated: 55190; Mature: 55190

Theoretical pI: Translated: 10.43; Mature: 10.43

Prosite motif: PS00300 SRP54

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
7.4 %Met     (Translated Protein)
7.4 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
7.4 %Met     (Mature Protein)
7.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFENLQDRLGSILNGLTGRGALSEADVSAALREVRRALLEADVALDVVRSFTDRVREKAV
CCCCHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GAEILKSIKPGQMVVKIVHDELIEMLGGEGVGIDLHAPAPVVVMMVGLQGSGKTTTSAKI
HHHHHHHCCCHHHHHHHHHHHHHHHHCCCCCCEEECCCCCEEEEEECCCCCCCCCHHHHH
AHRLSTRDKKKVLMASLDTRRPAAQEQLRQLGAQASIDTLPIISGQSPTDIAARAVQAAR
HHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHCCCCCCCCCEEECCCCCHHHHHHHHHHHH
LGGHDVVILDTAGRTHIDEPLMVEMADIKKRSNPHEILLVADSLTGQDAVNLARNFDERV
CCCCCEEEEECCCCCCCCCCHHHHHHHHHHCCCCCEEEEEECCCCCHHHHHHHHHHHHHC
GITGLVLTRMDGDGRGGAALSMRAVTGKPIKLIGVGEKMSELEEFHPRRIADRILGMGDI
CCEEEEEEEECCCCCCCCEEEEEEECCCCEEEEECCHHHHHHHHHHHHHHHHHHCCHHHH
VSLVERAAENIDAEKAAAMAAKMAKGKFDLDDLADQLRQMQKMGGMGGIMGMMPGMAGMK
HHHHHHHHHCCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCCCCHHHHCCCCCCCH
DKMAAAGLDDRLFGRQIAIIQSMTKAERANPDLLKHSRKKRIAAGSGTDAAAINKLLKMH
HHHHHCCCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCCCHHHHHHHHHHH
RQMADMMKMMGGKGKGGMMKQMMGGLAGKMGLGGLGGMGGMPDLSNMDPKQLEALQKQAE
HHHHHHHHHHCCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHH
AAGLGKPGGGMPGLGGGLPGGLPGLGGAKLPGLGGGFPGLPGLPKKK
HCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure
MFENLQDRLGSILNGLTGRGALSEADVSAALREVRRALLEADVALDVVRSFTDRVREKAV
CCCCHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GAEILKSIKPGQMVVKIVHDELIEMLGGEGVGIDLHAPAPVVVMMVGLQGSGKTTTSAKI
HHHHHHHCCCHHHHHHHHHHHHHHHHCCCCCCEEECCCCCEEEEEECCCCCCCCCHHHHH
AHRLSTRDKKKVLMASLDTRRPAAQEQLRQLGAQASIDTLPIISGQSPTDIAARAVQAAR
HHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHCCCCCCCCCEEECCCCCHHHHHHHHHHHH
LGGHDVVILDTAGRTHIDEPLMVEMADIKKRSNPHEILLVADSLTGQDAVNLARNFDERV
CCCCCEEEEECCCCCCCCCCHHHHHHHHHHCCCCCEEEEEECCCCCHHHHHHHHHHHHHC
GITGLVLTRMDGDGRGGAALSMRAVTGKPIKLIGVGEKMSELEEFHPRRIADRILGMGDI
CCEEEEEEEECCCCCCCCEEEEEEECCCCEEEEECCHHHHHHHHHHHHHHHHHHCCHHHH
VSLVERAAENIDAEKAAAMAAKMAKGKFDLDDLADQLRQMQKMGGMGGIMGMMPGMAGMK
HHHHHHHHHCCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCCCCHHHHCCCCCCCH
DKMAAAGLDDRLFGRQIAIIQSMTKAERANPDLLKHSRKKRIAAGSGTDAAAINKLLKMH
HHHHHCCCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCCCHHHHHHHHHHH
RQMADMMKMMGGKGKGGMMKQMMGGLAGKMGLGGLGGMGGMPDLSNMDPKQLEALQKQAE
HHHHHHHHHHCCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHH
AAGLGKPGGGMPGLGGGLPGGLPGLGGAKLPGLGGGFPGLPGLPKKK
HCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11557893 [H]