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The map label for this gene is cycZ [H]

Identifier: 209551312

GI number: 209551312

Start: 3868625

End: 3869386

Strand: Direct

Name: cycZ [H]

Synonym: Rleg2_3741

Alternate gene names: 209551312

Gene position: 3868625-3869386 (Clockwise)

Preceding gene: 209551311

Following gene: 209551313

Centisome position: 85.25

GC content: 63.65

Gene sequence:

>762_bases
ATGAGCCAAACGAGCCTTGCCATCAGCAAATTCAGCGATCTCGCCAACCCGACGCGGTTTCTGGCGCTGGCGGCACGCGT
CATTCCGTGGCTGGCCGGCATCACCGCCCTCTGTTTTCTGATCGGCCTCTATCTGAGCTTCTCCACGGAGGGCGATTACC
AGCAGGGCGAGACCGTGCGCATCATGTATGTCCACGTGCCCGCCGCCTGGCTGTCGATGATGTGCTATACGATCATGAGT
ATCTCGGCGATCGGCACGCTTGTCTGGCGCCATCCGCTGGCCGACGTCTCCGCCAAGGCCGCAGCCCCGCTCGGCGCCGC
CTTCACCCTGCTCGCGCTCGTCACCGGCTCGCTCTGGGGCAAGCCGATGTGGGGCACCTGGTGGGTCTGGGATGCGCGGC
TGACCTCGGTTTTCGTTCTCTTCCTGATGTATCTCGGCCTGATTGCGCTCAGCCGCGCCATCGACGATCCGTCGAAGGCC
GCGCGCGTTTCCGCCGTGCTCATCCTCGTCGGCTTCATCAATATCCCGATCATCAAATTTTCGGTCGAGTGGTGGAACAC
GCTGCATCAGTCGGCAAGCGTGATGCGCCTCGACGGCCCGGCGATCGACCCGGAATTCCTGCGGCCGCTCTTCGTCATGG
CGATTGCCTTCACCCTGCTCTTTTTCACGCTGCATATCATGGCGATGCGCAACGAGATCTGGCGCCGCCGCATCGCCGCC
CAGCGCCGTCTTGCCGCCCGCATGGCGAGCCGGGAGGAATAG

Upstream 100 bases:

>100_bases
GGTCATCGGCCCGGCTGCCGCCGCGCTGGCACTGCGAAACACGGCGGATTGACCAGCCATTCGATTGCGGGAAAAGCCGG
ATCAAGGTAAGGAAACGGAC

Downstream 100 bases:

>100_bases
CCGGTGACGCATGCCTTCTATGTCTACGCTTCCTATGGCTTCGCCGCCTTCATGACGGTCGCCGTCACGCTCTGGACCTG
GGCCGATGGCCGGGCCCGCC

Product: heme exporter protein CcmC

Products: NA

Alternate protein names: Cytochrome c-type biogenesis protein CycZ [H]

Number of amino acids: Translated: 253; Mature: 252

Protein sequence:

>253_residues
MSQTSLAISKFSDLANPTRFLALAARVIPWLAGITALCFLIGLYLSFSTEGDYQQGETVRIMYVHVPAAWLSMMCYTIMS
ISAIGTLVWRHPLADVSAKAAAPLGAAFTLLALVTGSLWGKPMWGTWWVWDARLTSVFVLFLMYLGLIALSRAIDDPSKA
ARVSAVLILVGFINIPIIKFSVEWWNTLHQSASVMRLDGPAIDPEFLRPLFVMAIAFTLLFFTLHIMAMRNEIWRRRIAA
QRRLAARMASREE

Sequences:

>Translated_253_residues
MSQTSLAISKFSDLANPTRFLALAARVIPWLAGITALCFLIGLYLSFSTEGDYQQGETVRIMYVHVPAAWLSMMCYTIMS
ISAIGTLVWRHPLADVSAKAAAPLGAAFTLLALVTGSLWGKPMWGTWWVWDARLTSVFVLFLMYLGLIALSRAIDDPSKA
ARVSAVLILVGFINIPIIKFSVEWWNTLHQSASVMRLDGPAIDPEFLRPLFVMAIAFTLLFFTLHIMAMRNEIWRRRIAA
QRRLAARMASREE
>Mature_252_residues
SQTSLAISKFSDLANPTRFLALAARVIPWLAGITALCFLIGLYLSFSTEGDYQQGETVRIMYVHVPAAWLSMMCYTIMSI
SAIGTLVWRHPLADVSAKAAAPLGAAFTLLALVTGSLWGKPMWGTWWVWDARLTSVFVLFLMYLGLIALSRAIDDPSKAA
RVSAVLILVGFINIPIIKFSVEWWNTLHQSASVMRLDGPAIDPEFLRPLFVMAIAFTLLFFTLHIMAMRNEIWRRRIAAQ
RRLAARMASREE

Specific function: Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes [H]

COG id: COG0755

COG function: function code O; ABC-type transport system involved in cytochrome c biogenesis, permease component

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the CcmC/CycZ/HelC family [H]

Homologues:

Organism=Escherichia coli, GI1788527, Length=226, Percent_Identity=48.2300884955752, Blast_Score=206, Evalue=1e-54,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002541
- InterPro:   IPR003557 [H]

Pfam domain/function: PF01578 Cytochrom_C_asm [H]

EC number: NA

Molecular weight: Translated: 28313; Mature: 28182

Theoretical pI: Translated: 10.24; Mature: 10.24

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
4.7 %Met     (Translated Protein)
5.5 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
4.4 %Met     (Mature Protein)
5.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSQTSLAISKFSDLANPTRFLALAARVIPWLAGITALCFLIGLYLSFSTEGDYQQGETVR
CCCHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEE
IMYVHVPAAWLSMMCYTIMSISAIGTLVWRHPLADVSAKAAAPLGAAFTLLALVTGSLWG
EEEEECCHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHCCCHHHHHHHHHHHHHHHCC
KPMWGTWWVWDARLTSVFVLFLMYLGLIALSRAIDDPSKAARVSAVLILVGFINIPIIKF
CCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCHHEE
SVEWWNTLHQSASVMRLDGPAIDPEFLRPLFVMAIAFTLLFFTLHIMAMRNEIWRRRIAA
EHHHHHHHHHCCCEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
QRRLAARMASREE
HHHHHHHHHCCCC
>Mature Secondary Structure 
SQTSLAISKFSDLANPTRFLALAARVIPWLAGITALCFLIGLYLSFSTEGDYQQGETVR
CCHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEE
IMYVHVPAAWLSMMCYTIMSISAIGTLVWRHPLADVSAKAAAPLGAAFTLLALVTGSLWG
EEEEECCHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHCCCHHHHHHHHHHHHHHHCC
KPMWGTWWVWDARLTSVFVLFLMYLGLIALSRAIDDPSKAARVSAVLILVGFINIPIIKF
CCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCHHEE
SVEWWNTLHQSASVMRLDGPAIDPEFLRPLFVMAIAFTLLFFTLHIMAMRNEIWRRRIAA
EHHHHHHHHHCCCEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
QRRLAARMASREE
HHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 1850420; 12597275 [H]