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The map label for this gene is cycW [H]

Identifier: 209551311

GI number: 209551311

Start: 3867917

End: 3868576

Strand: Direct

Name: cycW [H]

Synonym: Rleg2_3740

Alternate gene names: 209551311

Gene position: 3867917-3868576 (Clockwise)

Preceding gene: 209551310

Following gene: 209551312

Centisome position: 85.23

GC content: 67.27

Gene sequence:

>660_bases
ATGACCGCCCTCTTCCTCCGCGATCTCAAACTCTCGATCCGCGCCGGCGGCGGCGCGCTGGTTGGGGTATTGTTCTTCTT
GACGGTCGTTGCCGTCATCCCCTTCGGCGTCGGTCCCGATCTCAAGCTGCTGTCGCGCATCGGCCCCGCCATCGTCTGGA
TCGGCGCGCTGCTGGCAGCACTTCTCGGCCTCGACCGGCTGTTCCAGGCCGAGCGCGACGACGGATCGCTCGACCTGATG
CTGATGCAGGACACGCCGCTCGTCCTCACCGTACTCGTCAAATGCTTCGCCCACTGGACGGCGACCAGCCTGCCGCTGGT
CATCGCCTCGCCGCTGCTCGGCCTGTTCATGAATATGGACGAGACGGCGATCGGTGCCACCGCGCTGACGCTTCTGGTCG
GCTCGCCCGCCATCACCTTCATTGGCGCCGTCGGCGCCGCCGTCGCCGTGGCGCTACCGCGCGGCGGCCTGCTCGTTTCG
ATCCTGGTGCTGCCGCTCACCATCCCGGTGCTAATCTTCGGCGTCAGTGCCGCCTATGCCGCGGTCGAGGATCCCGCCCC
GTTCCTGCCGCCTTTCCTCATCCTCATCGCGCTGACGCTGTTCTTTGCGGTCATCGGCCCGGCTGCCGCCGCGCTGGCAC
TGCGAAACACGGCGGATTGA

Upstream 100 bases:

>100_bases
GAAGCTGGTGCATCTTGCCGATCTCCCCCCTTGTGGGGGAGATGCCCGGCAGGGCAGAGGGGGGTGCCCCGTCCACCACA
CATGTTGAGAGCTGCCCCGC

Downstream 100 bases:

>100_bases
CCAGCCATTCGATTGCGGGAAAAGCCGGATCAAGGTAAGGAAACGGACATGAGCCAAACGAGCCTTGCCATCAGCAAATT
CAGCGATCTCGCCAACCCGA

Product: heme exporter protein CcmB

Products: NA

Alternate protein names: Cytochrome c-type biogenesis protein CycW [H]

Number of amino acids: Translated: 219; Mature: 218

Protein sequence:

>219_residues
MTALFLRDLKLSIRAGGGALVGVLFFLTVVAVIPFGVGPDLKLLSRIGPAIVWIGALLAALLGLDRLFQAERDDGSLDLM
LMQDTPLVLTVLVKCFAHWTATSLPLVIASPLLGLFMNMDETAIGATALTLLVGSPAITFIGAVGAAVAVALPRGGLLVS
ILVLPLTIPVLIFGVSAAYAAVEDPAPFLPPFLILIALTLFFAVIGPAAAALALRNTAD

Sequences:

>Translated_219_residues
MTALFLRDLKLSIRAGGGALVGVLFFLTVVAVIPFGVGPDLKLLSRIGPAIVWIGALLAALLGLDRLFQAERDDGSLDLM
LMQDTPLVLTVLVKCFAHWTATSLPLVIASPLLGLFMNMDETAIGATALTLLVGSPAITFIGAVGAAVAVALPRGGLLVS
ILVLPLTIPVLIFGVSAAYAAVEDPAPFLPPFLILIALTLFFAVIGPAAAALALRNTAD
>Mature_218_residues
TALFLRDLKLSIRAGGGALVGVLFFLTVVAVIPFGVGPDLKLLSRIGPAIVWIGALLAALLGLDRLFQAERDDGSLDLML
MQDTPLVLTVLVKCFAHWTATSLPLVIASPLLGLFMNMDETAIGATALTLLVGSPAITFIGAVGAAVAVALPRGGLLVSI
LVLPLTIPVLIFGVSAAYAAVEDPAPFLPPFLILIALTLFFAVIGPAAAALALRNTAD

Specific function: Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes [H]

COG id: COG2386

COG function: function code O; ABC-type transport system involved in cytochrome c biogenesis, permease component

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the CcmB/CycW/HelB family [H]

Homologues:

Organism=Escherichia coli, GI1788528, Length=212, Percent_Identity=44.3396226415094, Blast_Score=117, Evalue=4e-28,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003544 [H]

Pfam domain/function: PF03379 CcmB [H]

EC number: NA

Molecular weight: Translated: 22591; Mature: 22459

Theoretical pI: Translated: 4.71; Mature: 4.71

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTALFLRDLKLSIRAGGGALVGVLFFLTVVAVIPFGVGPDLKLLSRIGPAIVWIGALLAA
CCHHHHHHHHHEEECCCHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHH
LLGLDRLFQAERDDGSLDLMLMQDTPLVLTVLVKCFAHWTATSLPLVIASPLLGLFMNMD
HHHHHHHHHCCCCCCCEEEEEECCCCHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCC
ETAIGATALTLLVGSPAITFIGAVGAAVAVALPRGGLLVSILVLPLTIPVLIFGVSAAYA
HHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
AVEDPAPFLPPFLILIALTLFFAVIGPAAAALALRNTAD
HHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure 
TALFLRDLKLSIRAGGGALVGVLFFLTVVAVIPFGVGPDLKLLSRIGPAIVWIGALLAA
CHHHHHHHHHEEECCCHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHH
LLGLDRLFQAERDDGSLDLMLMQDTPLVLTVLVKCFAHWTATSLPLVIASPLLGLFMNMD
HHHHHHHHHCCCCCCCEEEEEECCCCHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCC
ETAIGATALTLLVGSPAITFIGAVGAAVAVALPRGGLLVSILVLPLTIPVLIFGVSAAYA
HHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
AVEDPAPFLPPFLILIALTLFFAVIGPAAAALALRNTAD
HHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 1850420; 12597275 [H]