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The map label for this gene is rhtB [H]

Identifier: 209551292

GI number: 209551292

Start: 3848298

End: 3848939

Strand: Direct

Name: rhtB [H]

Synonym: Rleg2_3720

Alternate gene names: 209551292

Gene position: 3848298-3848939 (Clockwise)

Preceding gene: 209551291

Following gene: 209551298

Centisome position: 84.8

GC content: 62.93

Gene sequence:

>642_bases
ATGGATTTCCTGCCCAGCCTGTCGACGCTTCTCGCCTTCGCCGCCGCGACGCTGTTGCTCGCGGCGACCCCGGGCCCCGA
CATGACGCTATCGATCAGCCGTTCGCTGGCCCAAGGCAAGAAGGCGGCTCTTTTCGTCGTTGTCGGCACCAGCCTCGGCA
TCGTCGTTCACACCATGCTGGTCGCCTTCGGCATTTCGGCGCTGATCACCGCCTCGCCGACCGCTTTCCTGATCCTGAAG
ACCGGCGGCGCCGCCTATCTGCTCTGGCTGGCGGTGCAGGCGATCCGCTTCGGCTCGAAGCTGACCGTCGCCAAGGTCGA
GGCGCAGAAAGGCACCGCGCTTGCGAACATCTCGTGGGGCTTCTGGGTCAATCTTCTGAACCCCAAGGTCATCATCTTCT
TCATGACCTTCCTGCCGCAATTCGTCAGCGCCGGCGATCCCGCCGTGACGCAAAAGCTGCTTTTCCTCGGGTTTTGCTTC
ATCGTGATCGGCATGCCGGTCAATGCCGGCGTGATCCTTGCCGCCGACTGGCTGGCCTCCTGGCTGCAGACCAACAGGAA
GGTGTTGCGCGGCATCGACTATACCTTCGCCGGCGTCTTCTCGATCTTCGCCGCAAAGATCCTGCTCACCCAGGCCAGGT
GA

Upstream 100 bases:

>100_bases
CCTGGAACAGAAGTGATCGTTACTATTCCAAGGTTTGATTGGTAATTTTCTGGAAGCCGAGTAAGAAATCGTCGGATCTT
TCCGGCTTTCAGAGTGTGCC

Downstream 100 bases:

>100_bases
TCAGCACCATGTCAGGCTAGCCGATCAGCAAAGCATCGTCGTCGAGTGTCTGGCCGCGCATCTTGCGGAACATGGCGATC
AGATCCTCGACCTGCAGGTT

Product: lysine exporter protein LysE/YggA

Products: homoserine lactone [Periplasm]; Proton [Cytoplasm]; homoserine [Periplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 213; Mature: 213

Protein sequence:

>213_residues
MDFLPSLSTLLAFAAATLLLAATPGPDMTLSISRSLAQGKKAALFVVVGTSLGIVVHTMLVAFGISALITASPTAFLILK
TGGAAYLLWLAVQAIRFGSKLTVAKVEAQKGTALANISWGFWVNLLNPKVIIFFMTFLPQFVSAGDPAVTQKLLFLGFCF
IVIGMPVNAGVILAADWLASWLQTNRKVLRGIDYTFAGVFSIFAAKILLTQAR

Sequences:

>Translated_213_residues
MDFLPSLSTLLAFAAATLLLAATPGPDMTLSISRSLAQGKKAALFVVVGTSLGIVVHTMLVAFGISALITASPTAFLILK
TGGAAYLLWLAVQAIRFGSKLTVAKVEAQKGTALANISWGFWVNLLNPKVIIFFMTFLPQFVSAGDPAVTQKLLFLGFCF
IVIGMPVNAGVILAADWLASWLQTNRKVLRGIDYTFAGVFSIFAAKILLTQAR
>Mature_213_residues
MDFLPSLSTLLAFAAATLLLAATPGPDMTLSISRSLAQGKKAALFVVVGTSLGIVVHTMLVAFGISALITASPTAFLILK
TGGAAYLLWLAVQAIRFGSKLTVAKVEAQKGTALANISWGFWVNLLNPKVIIFFMTFLPQFVSAGDPAVTQKLLFLGFCF
IVIGMPVNAGVILAADWLASWLQTNRKVLRGIDYTFAGVFSIFAAKILLTQAR

Specific function: Conducts the efflux of homoserine and homoserine lactone [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the rht family [H]

Homologues:

Organism=Escherichia coli, GI48994979, Length=202, Percent_Identity=29.7029702970297, Blast_Score=85, Evalue=4e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004778
- InterPro:   IPR001123 [H]

Pfam domain/function: PF01810 LysE [H]

EC number: NA

Molecular weight: Translated: 22654; Mature: 22654

Theoretical pI: Translated: 10.84; Mature: 10.84

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDFLPSLSTLLAFAAATLLLAATPGPDMTLSISRSLAQGKKAALFVVVGTSLGIVVHTML
CCCCCHHHHHHHHHHHHHHHEECCCCCEEEEEHHHHHCCCCEEEEEEECCHHHHHHHHHH
VAFGISALITASPTAFLILKTGGAAYLLWLAVQAIRFGSKLTVAKVEAQKGTALANISWG
HHHHHHHHHCCCCCEEEEEECCCHHHHHHHHHHHHHCCCCEEEEEEECCCCCEEEECCHH
FWVNLLNPKVIIFFMTFLPQFVSAGDPAVTQKLLFLGFCFIVIGMPVNAGVILAADWLAS
HEEEECCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCCCCCEEEHHHHHHH
WLQTNRKVLRGIDYTFAGVFSIFAAKILLTQAR
HHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MDFLPSLSTLLAFAAATLLLAATPGPDMTLSISRSLAQGKKAALFVVVGTSLGIVVHTML
CCCCCHHHHHHHHHHHHHHHEECCCCCEEEEEHHHHHCCCCEEEEEEECCHHHHHHHHHH
VAFGISALITASPTAFLILKTGGAAYLLWLAVQAIRFGSKLTVAKVEAQKGTALANISWG
HHHHHHHHHCCCCCEEEEEECCCHHHHHHHHHHHHHCCCCEEEEEEECCCCCEEEECCHH
FWVNLLNPKVIIFFMTFLPQFVSAGDPAVTQKLLFLGFCFIVIGMPVNAGVILAADWLAS
HEEEECCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCCCCCEEEHHHHHHH
WLQTNRKVLRGIDYTFAGVFSIFAAKILLTQAR
HHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Proton [Periplasm]; homoserine [Cytoplasm] [C]

Specific reaction: Proton [Periplasm] + homoserine lactone [Cytoplasm] = Proton [Cytoplasm] + homoserine lactone [Periplasm] Proton [Periplasm] + homoserine [Cytoplasm] = Proton [Cytoplasm] + homoserine [Periplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]