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The map label for this gene is dcp [H]

Identifier: 209551283

GI number: 209551283

Start: 3838192

End: 3840279

Strand: Reverse

Name: dcp [H]

Synonym: Rleg2_3711

Alternate gene names: 209551283

Gene position: 3840279-3838192 (Counterclockwise)

Preceding gene: 209551285

Following gene: 209551282

Centisome position: 84.63

GC content: 62.26

Gene sequence:

>2088_bases
ATGCCTTCTCCCCATGATTTCAATCCGGCGCTGGTGACTTGGGACGGCCTTCACGGCCTGCCGCGTTTCGATGCCGTCGA
TGACGGCGATTTCGCTGCCGCCTTCGAAGCGGCGCTTGCCGCCCATGAACGGGAGATCGACGAGATTGCCGGAAATGCCG
AGGCGCCGACATTCGACAATACGGTCACGGCGCTGGAGATAGCCGGCGATGCACTGTCGCGCGTTTCGGCGCTGTTCTGG
AACAAGGCGGGCGCGCATACCAATGATGTGATCCAGGCGCTGGAGCGGGAGATCTCGCCGAAGATGTCGCGCCACTATTC
GAAGATCGGCATGAATGCCGCGCTCTTTTCCCGCATCGACACGCTTTGGGAGAAACGCGAAAGCCTCGGCTTGACGCTCG
AGCAGACACGCGTGCTGGAGCGCCACTGGAAAGGCTTCGTCAAATCCGGCGCCAAGCTCGAGAAGGCCGAACAGGAGAAA
CTGGCAGCGATCAATGAAAAGCTTGCCGGCCTCAGCACGCAATTCGGCCAGAACGTGCTCGCCGACGAGAAGGCCTGGGC
ACTCACGCTGTCTTCTGGAGCCGAGCTCGACGGGCTGCCGGAATTTTTGCGGGACGCCATGGCCGCAGCTGCACGCGAAC
GCGGTGAAGAGGGCAAATATGCGGTGACGCTGTCACGCTCGATCATCGAGCCGTTCCTGACCTTTTCGGAGCGCCGCGAC
CTGCGCGAGCAGGCTTTCAAGGCGTGGGTGGCGCGCGGCGAAAATGACGGCGAGACGGACAATCGCGCCGTTATCCGAGA
AACGCTGGCGCTGCGCCATCAGGTGGCGAGCCTGCTTGGTTACGGCAATTTCGCCGAGCTGAAGCTCGACAACACGATGG
CAAAGACGGCGGAGGCGGTGAACGACCTGCTCAAAGCGGTCTGGGCGCGGGCGGTGAAACGCGCCGGCGAGGAGGAGGCC
GACATTGCCGCGCTGATCGCCGAGGAAGGGCGCAACCACGAGGTGATGCCCTGGGACTGGCGCCATTACGCCGAAAAGAT
TAGGGCGCGGAAATTCGATTTTTCCGAGGCCGAGCTCAAGCCCTATCTGCAGCTCGAGAAGATCGTCGAAGCCTGCTTCG
ACGTGGCCGGCCGGCTCTTCGGCATCCGCGCCGTCGAGAAGAAGGGCGTGGCCGCCTATCATCCGGATGTCAGGGTGTTC
GAAATCAGGGATCGCGAAGATCGGCTGGTCGCGCTTTTCCTTGGCGATTATTTCGCCCGTGGCTCGAAACGATCAGGCGC
CTGGATGAGCTCGCTGCAATCGCAGCATAGGCTGGAGCTGAAGAACGGCCGCCACGGCGAGCTGCCGATCATCTACAATG
TCTGCAACTTCGCCAAACCCGCCGAGGGCAAGCCGGCGCTGCTGTCGCTCGACGATGCGCGCACGCTGTTCCACGAATTC
GGCCACGCGCTGCACGGCATGCTTTCTGATGTCACCTACCCCTCGGTCTCCGGCACCAGCGTTTCGCGCGATTTCGTCGA
GCTGCCGTCGCAGCTCTACGAGCACTGGCTGACGGTGCCCGCTATTCTGAAGCGCTATGCCGTGCATGTCGAAACCGGCG
AGCCGATGCCGCAGGCGCTGCTCGACAAGGTGCTGGCGGCGCGCACCTTCAATGCCGGCTTCAACACCGTCGAGTTCACC
TCGTCGGCGCTGGTTGATATGGCCTTTCACACGCGGGAGGCGGTTGCGGATCCGATGGCGGTGCAGGCCGAGGTGCTTGC
CGAGATCGGCATGCCGAAATCGATCGTCATGCGCCACGCGACGCCGCACTTCCAGCACATTTTCTCCGGCGGTTATTCGG
CCGGCTATTACTCCTATATGTGGTCGGAGGTGCTCGACGCCGACGCCTTTGCCGCTTTCGAGGAGACGGGAGACGCATTC
AACGGCGAGATGGCGCGCAAGCTCAAGGAAAACATCTATTCCGTCGGTGGCTCGGTCGATCCGGAGGACGCCTATAAGGC
TTTCCGCGGCAAGCTGCCGAGCCCCGATGCGATGCTGGTCAAAAAGGGACTTTCGACCTTCGAGGAATTGACAGGCAGCG
ACGCCTAA

Upstream 100 bases:

>100_bases
CCAGATTTTGCAGGCGAGTCAAAAGACCCTTCCCGCATACCAATTCTACGACAGCTCTCCTATATTGACGAACCCGTGCA
TGCCAAAAAGGAATTCTCCG

Downstream 100 bases:

>100_bases
GACAATTTGATGACACGCTTCGATGCGGCATGGCGGCAGCCATGCCGCAGCTTTTGCGCGTTCCCCTCTTTCGCAAACGC
AAAAAAAACTGTATGGACGC

Product: peptidyl-dipeptidase Dcp

Products: NA

Alternate protein names: Dipeptidyl carboxypeptidase [H]

Number of amino acids: Translated: 695; Mature: 694

Protein sequence:

>695_residues
MPSPHDFNPALVTWDGLHGLPRFDAVDDGDFAAAFEAALAAHEREIDEIAGNAEAPTFDNTVTALEIAGDALSRVSALFW
NKAGAHTNDVIQALEREISPKMSRHYSKIGMNAALFSRIDTLWEKRESLGLTLEQTRVLERHWKGFVKSGAKLEKAEQEK
LAAINEKLAGLSTQFGQNVLADEKAWALTLSSGAELDGLPEFLRDAMAAAARERGEEGKYAVTLSRSIIEPFLTFSERRD
LREQAFKAWVARGENDGETDNRAVIRETLALRHQVASLLGYGNFAELKLDNTMAKTAEAVNDLLKAVWARAVKRAGEEEA
DIAALIAEEGRNHEVMPWDWRHYAEKIRARKFDFSEAELKPYLQLEKIVEACFDVAGRLFGIRAVEKKGVAAYHPDVRVF
EIRDREDRLVALFLGDYFARGSKRSGAWMSSLQSQHRLELKNGRHGELPIIYNVCNFAKPAEGKPALLSLDDARTLFHEF
GHALHGMLSDVTYPSVSGTSVSRDFVELPSQLYEHWLTVPAILKRYAVHVETGEPMPQALLDKVLAARTFNAGFNTVEFT
SSALVDMAFHTREAVADPMAVQAEVLAEIGMPKSIVMRHATPHFQHIFSGGYSAGYYSYMWSEVLDADAFAAFEETGDAF
NGEMARKLKENIYSVGGSVDPEDAYKAFRGKLPSPDAMLVKKGLSTFEELTGSDA

Sequences:

>Translated_695_residues
MPSPHDFNPALVTWDGLHGLPRFDAVDDGDFAAAFEAALAAHEREIDEIAGNAEAPTFDNTVTALEIAGDALSRVSALFW
NKAGAHTNDVIQALEREISPKMSRHYSKIGMNAALFSRIDTLWEKRESLGLTLEQTRVLERHWKGFVKSGAKLEKAEQEK
LAAINEKLAGLSTQFGQNVLADEKAWALTLSSGAELDGLPEFLRDAMAAAARERGEEGKYAVTLSRSIIEPFLTFSERRD
LREQAFKAWVARGENDGETDNRAVIRETLALRHQVASLLGYGNFAELKLDNTMAKTAEAVNDLLKAVWARAVKRAGEEEA
DIAALIAEEGRNHEVMPWDWRHYAEKIRARKFDFSEAELKPYLQLEKIVEACFDVAGRLFGIRAVEKKGVAAYHPDVRVF
EIRDREDRLVALFLGDYFARGSKRSGAWMSSLQSQHRLELKNGRHGELPIIYNVCNFAKPAEGKPALLSLDDARTLFHEF
GHALHGMLSDVTYPSVSGTSVSRDFVELPSQLYEHWLTVPAILKRYAVHVETGEPMPQALLDKVLAARTFNAGFNTVEFT
SSALVDMAFHTREAVADPMAVQAEVLAEIGMPKSIVMRHATPHFQHIFSGGYSAGYYSYMWSEVLDADAFAAFEETGDAF
NGEMARKLKENIYSVGGSVDPEDAYKAFRGKLPSPDAMLVKKGLSTFEELTGSDA
>Mature_694_residues
PSPHDFNPALVTWDGLHGLPRFDAVDDGDFAAAFEAALAAHEREIDEIAGNAEAPTFDNTVTALEIAGDALSRVSALFWN
KAGAHTNDVIQALEREISPKMSRHYSKIGMNAALFSRIDTLWEKRESLGLTLEQTRVLERHWKGFVKSGAKLEKAEQEKL
AAINEKLAGLSTQFGQNVLADEKAWALTLSSGAELDGLPEFLRDAMAAAARERGEEGKYAVTLSRSIIEPFLTFSERRDL
REQAFKAWVARGENDGETDNRAVIRETLALRHQVASLLGYGNFAELKLDNTMAKTAEAVNDLLKAVWARAVKRAGEEEAD
IAALIAEEGRNHEVMPWDWRHYAEKIRARKFDFSEAELKPYLQLEKIVEACFDVAGRLFGIRAVEKKGVAAYHPDVRVFE
IRDREDRLVALFLGDYFARGSKRSGAWMSSLQSQHRLELKNGRHGELPIIYNVCNFAKPAEGKPALLSLDDARTLFHEFG
HALHGMLSDVTYPSVSGTSVSRDFVELPSQLYEHWLTVPAILKRYAVHVETGEPMPQALLDKVLAARTFNAGFNTVEFTS
SALVDMAFHTREAVADPMAVQAEVLAEIGMPKSIVMRHATPHFQHIFSGGYSAGYYSYMWSEVLDADAFAAFEETGDAFN
GEMARKLKENIYSVGGSVDPEDAYKAFRGKLPSPDAMLVKKGLSTFEELTGSDA

Specific function: Removes dipeptides from the C-termini of N-blocked tripeptides, tetrapeptides and larger peptides [H]

COG id: COG0339

COG function: function code E; Zn-dependent oligopeptidases

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M3 family [H]

Homologues:

Organism=Homo sapiens, GI4507491, Length=615, Percent_Identity=31.5447154471545, Blast_Score=254, Evalue=3e-67,
Organism=Homo sapiens, GI14149738, Length=609, Percent_Identity=27.5862068965517, Blast_Score=204, Evalue=2e-52,
Organism=Homo sapiens, GI156105687, Length=672, Percent_Identity=24.8511904761905, Blast_Score=173, Evalue=5e-43,
Organism=Escherichia coli, GI1787819, Length=684, Percent_Identity=40.6432748538012, Blast_Score=481, Evalue=1e-137,
Organism=Escherichia coli, GI1789913, Length=691, Percent_Identity=36.0347322720695, Blast_Score=385, Evalue=1e-108,
Organism=Caenorhabditis elegans, GI32565901, Length=631, Percent_Identity=21.0776545166403, Blast_Score=89, Evalue=1e-17,
Organism=Caenorhabditis elegans, GI71999758, Length=584, Percent_Identity=21.5753424657534, Blast_Score=74, Evalue=4e-13,
Organism=Saccharomyces cerevisiae, GI6319793, Length=592, Percent_Identity=26.1824324324324, Blast_Score=200, Evalue=6e-52,
Organism=Saccharomyces cerevisiae, GI6322715, Length=731, Percent_Identity=22.5718194254446, Blast_Score=125, Evalue=3e-29,
Organism=Drosophila melanogaster, GI21356111, Length=513, Percent_Identity=25.1461988304094, Blast_Score=168, Evalue=1e-41,
Organism=Drosophila melanogaster, GI20129717, Length=458, Percent_Identity=24.235807860262, Blast_Score=131, Evalue=1e-30,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001567 [H]

Pfam domain/function: PF01432 Peptidase_M3 [H]

EC number: =3.4.15.5 [H]

Molecular weight: Translated: 77108; Mature: 76977

Theoretical pI: Translated: 5.31; Mature: 5.31

Prosite motif: PS00142 ZINC_PROTEASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPSPHDFNPALVTWDGLHGLPRFDAVDDGDFAAAFEAALAAHEREIDEIAGNAEAPTFDN
CCCCCCCCCCEEEECCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCC
TVTALEIAGDALSRVSALFWNKAGAHTNDVIQALEREISPKMSRHYSKIGMNAALFSRID
CHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCHHHHHHHHHHCCHHHHHHHHH
TLWEKRESLGLTLEQTRVLERHWKGFVKSGAKLEKAEQEKLAAINEKLAGLSTQFGQNVL
HHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHCCHHH
ADEKAWALTLSSGAELDGLPEFLRDAMAAAARERGEEGKYAVTLSRSIIEPFLTFSERRD
CCCCCEEEEECCCCCCCCHHHHHHHHHHHHHHHCCCCCCEEEEEHHHHHHHHHHHHHHHH
LREQAFKAWVARGENDGETDNRAVIRETLALRHQVASLLGYGNFAELKLDNTMAKTAEAV
HHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCEEEEEECHHHHHHHHHH
NDLLKAVWARAVKRAGEEEADIAALIAEEGRNHEVMPWDWRHYAEKIRARKFDFSEAELK
HHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHCCCCCHHHHH
PYLQLEKIVEACFDVAGRLFGIRAVEKKGVAAYHPDVRVFEIRDREDRLVALFLGDYFAR
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEECCCCEEEEECCCCCCEEEEHHHHHHHC
GSKRSGAWMSSLQSQHRLELKNGRHGELPIIYNVCNFAKPAEGKPALLSLDDARTLFHEF
CCCCCCHHHHHHHHHHHHHHCCCCCCCCCEEEEHHCCCCCCCCCCCEEECHHHHHHHHHH
GHALHGMLSDVTYPSVSGTSVSRDFVELPSQLYEHWLTVPAILKRYAVHVETGEPMPQAL
HHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHEEEECCCCCCHHHH
LDKVLAARTFNAGFNTVEFTSSALVDMAFHTREAVADPMAVQAEVLAEIGMPKSIVMRHA
HHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCHHHHHHCC
TPHFQHIFSGGYSAGYYSYMWSEVLDADAFAAFEETGDAFNGEMARKLKENIYSVGGSVD
CHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHCCCCCC
PEDAYKAFRGKLPSPDAMLVKKGLSTFEELTGSDA
HHHHHHHHHCCCCCCHHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure 
PSPHDFNPALVTWDGLHGLPRFDAVDDGDFAAAFEAALAAHEREIDEIAGNAEAPTFDN
CCCCCCCCCEEEECCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCC
TVTALEIAGDALSRVSALFWNKAGAHTNDVIQALEREISPKMSRHYSKIGMNAALFSRID
CHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCHHHHHHHHHHCCHHHHHHHHH
TLWEKRESLGLTLEQTRVLERHWKGFVKSGAKLEKAEQEKLAAINEKLAGLSTQFGQNVL
HHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHCCHHH
ADEKAWALTLSSGAELDGLPEFLRDAMAAAARERGEEGKYAVTLSRSIIEPFLTFSERRD
CCCCCEEEEECCCCCCCCHHHHHHHHHHHHHHHCCCCCCEEEEEHHHHHHHHHHHHHHHH
LREQAFKAWVARGENDGETDNRAVIRETLALRHQVASLLGYGNFAELKLDNTMAKTAEAV
HHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCEEEEEECHHHHHHHHHH
NDLLKAVWARAVKRAGEEEADIAALIAEEGRNHEVMPWDWRHYAEKIRARKFDFSEAELK
HHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHCCCCCHHHHH
PYLQLEKIVEACFDVAGRLFGIRAVEKKGVAAYHPDVRVFEIRDREDRLVALFLGDYFAR
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEECCCCEEEEECCCCCCEEEEHHHHHHHC
GSKRSGAWMSSLQSQHRLELKNGRHGELPIIYNVCNFAKPAEGKPALLSLDDARTLFHEF
CCCCCCHHHHHHHHHHHHHHCCCCCCCCCEEEEHHCCCCCCCCCCCEEECHHHHHHHHHH
GHALHGMLSDVTYPSVSGTSVSRDFVELPSQLYEHWLTVPAILKRYAVHVETGEPMPQAL
HHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHEEEECCCCCCHHHH
LDKVLAARTFNAGFNTVEFTSSALVDMAFHTREAVADPMAVQAEVLAEIGMPKSIVMRHA
HHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCHHHHHHCC
TPHFQHIFSGGYSAGYYSYMWSEVLDADAFAAFEETGDAFNGEMARKLKENIYSVGGSVD
CHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHCCCCCC
PEDAYKAFRGKLPSPDAMLVKKGLSTFEELTGSDA
HHHHHHHHHCCCCCCHHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8226676; 9097039; 9278503 [H]