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The map label for this gene is gcp [H]

Identifier: 209551270

GI number: 209551270

Start: 3825767

End: 3826864

Strand: Reverse

Name: gcp [H]

Synonym: Rleg2_3698

Alternate gene names: 209551270

Gene position: 3826864-3825767 (Counterclockwise)

Preceding gene: 209551277

Following gene: 209551269

Centisome position: 84.33

GC content: 66.39

Gene sequence:

>1098_bases
ATGGTTCCCTTTCTGCGTATCCTTGGCATCGAAACGAGCTGCGACGAGACCGCGGCCGCCGTCGTCGAGCGCGATGCGGA
GGGAAATGCCAGAGTGCTCTCCGATGTGGTGCTGTCCCAGCTCGACGAGCATAGCGCCTATGGCGGCGTGGTGCCGGAGA
TCGCGGCACGCGCCCATGTCGAGGCGCTGGACGAGCTGATCGAGGAGGCGCTGAACCGCGCCAATGTGTCGCTTGATGAG
GTCGACGCCATCGCCGCGACGTCCGGGCCGGGGTTGATCGGCGGCCTGCTGGTGGGGTTGATGACCGGCAAGGCGATCGC
GAGGGCCGCCGGCAAACCGCTCTATGCGGTCAACCATCTCGAAGGCCATGCGCTGACGGCGCGGCTGACCGACGGGCTTG
CCTTTCCCTATCTGATGCTGCTCGTTTCCGGCGGCCATACCCAGCTGATCCTGGTGCGCGGCGTCGGCGAGTATCAGCGC
TGGGGCACGACGATCGACGATGCGCTCGGCGAGGCTTTCGACAAGACGGCAAAGCTGCTCGGTCTGCCCTATCCCGGCGG
CCCGGCGGTGGAACGGATGGCGCGGGACGGCAATCCCGACCGCTTCGCGTTTCCGCGGCCGCTGGTCGGCGAGGCGCGGC
TCGATTTCTCCTTCTCCGGGCTGAAGACGGCGGTGCGGCAGGCGGCACAGGATATCGCGCCGATCAGCGATCAGGACGTG
GCCGATATCTGCGCCTCGTTCCAGAAAGCGATTTCGCGAACGCTGAAGGATCGCATCGGCCGCGGCCTGCAGCGGTTCAA
AACGGAATTTGCCGCGACCGATGAGAAGCCGGCGCTCGTCGTTGCCGGCGGTGTCGCCGCCAATCTCGAACTGCGCGGCA
CGCTGCAGGCGCTCTGCGACAAAAACGGCTTTCGCTTCATTGCGCCGCCGCTGCACCTCTGCACCGACAATGCCGTGATG
ATCGCCTGGGCGGGACTGGAGCGCATGGCGACGGGCGCTGCACCGGATCCGCTCGACGTCCAGCCGCGTTCGCGCTGGCC
GCTCGATTCCAATGCGGAAACGCTGATCGGTTTCGGCAAGAGAGGAGCCAAGGCATGA

Upstream 100 bases:

>100_bases
TGCCGATCCGGAAAGGTTTTGTTTGCATCCGCTCAGTTCCGTTGTTACCGGAGTTCTCGTAAACGGGTTTCCATCCCATC
GCAATCAACGAACAGGCCTC

Downstream 100 bases:

>100_bases
GCGAAAACATCGCCGTCGTCGGATCGGGAGCTTTCGGAACGGCGCTCGCCGCCGTCATCGCCCTTGCCGGCCGCAGCGCG
GTGACGCTTGTCGGGCGCAA

Product: DNA-binding/iron metalloprotein/AP endonuclease

Products: NA

Alternate protein names: Glycoprotease [H]

Number of amino acids: Translated: 365; Mature: 365

Protein sequence:

>365_residues
MVPFLRILGIETSCDETAAAVVERDAEGNARVLSDVVLSQLDEHSAYGGVVPEIAARAHVEALDELIEEALNRANVSLDE
VDAIAATSGPGLIGGLLVGLMTGKAIARAAGKPLYAVNHLEGHALTARLTDGLAFPYLMLLVSGGHTQLILVRGVGEYQR
WGTTIDDALGEAFDKTAKLLGLPYPGGPAVERMARDGNPDRFAFPRPLVGEARLDFSFSGLKTAVRQAAQDIAPISDQDV
ADICASFQKAISRTLKDRIGRGLQRFKTEFAATDEKPALVVAGGVAANLELRGTLQALCDKNGFRFIAPPLHLCTDNAVM
IAWAGLERMATGAAPDPLDVQPRSRWPLDSNAETLIGFGKRGAKA

Sequences:

>Translated_365_residues
MVPFLRILGIETSCDETAAAVVERDAEGNARVLSDVVLSQLDEHSAYGGVVPEIAARAHVEALDELIEEALNRANVSLDE
VDAIAATSGPGLIGGLLVGLMTGKAIARAAGKPLYAVNHLEGHALTARLTDGLAFPYLMLLVSGGHTQLILVRGVGEYQR
WGTTIDDALGEAFDKTAKLLGLPYPGGPAVERMARDGNPDRFAFPRPLVGEARLDFSFSGLKTAVRQAAQDIAPISDQDV
ADICASFQKAISRTLKDRIGRGLQRFKTEFAATDEKPALVVAGGVAANLELRGTLQALCDKNGFRFIAPPLHLCTDNAVM
IAWAGLERMATGAAPDPLDVQPRSRWPLDSNAETLIGFGKRGAKA
>Mature_365_residues
MVPFLRILGIETSCDETAAAVVERDAEGNARVLSDVVLSQLDEHSAYGGVVPEIAARAHVEALDELIEEALNRANVSLDE
VDAIAATSGPGLIGGLLVGLMTGKAIARAAGKPLYAVNHLEGHALTARLTDGLAFPYLMLLVSGGHTQLILVRGVGEYQR
WGTTIDDALGEAFDKTAKLLGLPYPGGPAVERMARDGNPDRFAFPRPLVGEARLDFSFSGLKTAVRQAAQDIAPISDQDV
ADICASFQKAISRTLKDRIGRGLQRFKTEFAATDEKPALVVAGGVAANLELRGTLQALCDKNGFRFIAPPLHLCTDNAVM
IAWAGLERMATGAAPDPLDVQPRSRWPLDSNAETLIGFGKRGAKA

Specific function: Could Be A Metalloprotease. [C]

COG id: COG0533

COG function: function code O; Metal-dependent proteases with possible chaperone activity

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M22 family [H]

Homologues:

Organism=Homo sapiens, GI116812636, Length=340, Percent_Identity=38.2352941176471, Blast_Score=214, Evalue=1e-55,
Organism=Homo sapiens, GI8923380, Length=329, Percent_Identity=30.3951367781155, Blast_Score=130, Evalue=3e-30,
Organism=Escherichia coli, GI1789445, Length=346, Percent_Identity=48.2658959537572, Blast_Score=281, Evalue=4e-77,
Organism=Caenorhabditis elegans, GI17557464, Length=376, Percent_Identity=31.6489361702128, Blast_Score=161, Evalue=5e-40,
Organism=Caenorhabditis elegans, GI71995670, Length=351, Percent_Identity=31.0541310541311, Blast_Score=130, Evalue=1e-30,
Organism=Saccharomyces cerevisiae, GI6320099, Length=371, Percent_Identity=32.8840970350404, Blast_Score=177, Evalue=2e-45,
Organism=Saccharomyces cerevisiae, GI6322891, Length=300, Percent_Identity=27.3333333333333, Blast_Score=95, Evalue=2e-20,
Organism=Drosophila melanogaster, GI20129063, Length=364, Percent_Identity=36.2637362637363, Blast_Score=204, Evalue=8e-53,
Organism=Drosophila melanogaster, GI21357207, Length=341, Percent_Identity=29.6187683284457, Blast_Score=128, Evalue=8e-30,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR022450
- InterPro:   IPR000905
- InterPro:   IPR017861 [H]

Pfam domain/function: PF00814 Peptidase_M22 [H]

EC number: =3.4.24.57 [H]

Molecular weight: Translated: 38713; Mature: 38713

Theoretical pI: Translated: 5.13; Mature: 5.13

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVPFLRILGIETSCDETAAAVVERDAEGNARVLSDVVLSQLDEHSAYGGVVPEIAARAHV
CCCCEEHCCCCCCCHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHH
EALDELIEEALNRANVSLDEVDAIAATSGPGLIGGLLVGLMTGKAIARAAGKPLYAVNHL
HHHHHHHHHHHHHCCCCHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHCCCCEEEEECC
EGHALTARLTDGLAFPYLMLLVSGGHTQLILVRGVGEYQRWGTTIDDALGEAFDKTAKLL
CCCEEEEHHHCCHHHHHHHHHHCCCCEEEEEEECCCHHHHHCCCHHHHHHHHHHHHHHHH
GLPYPGGPAVERMARDGNPDRFAFPRPLVGEARLDFSFSGLKTAVRQAAQDIAPISDQDV
CCCCCCCHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCHH
ADICASFQKAISRTLKDRIGRGLQRFKTEFAATDEKPALVVAGGVAANLELRGTLQALCD
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEECCEEECEEHHHHHHHHHC
KNGFRFIAPPLHLCTDNAVMIAWAGLERMATGAAPDPLDVQPRSRWPLDSNAETLIGFGK
CCCCEEECCCHHHHCCCEEEEEECCHHHHHCCCCCCCCCCCCCCCCCCCCCCHHHEECCC
RGAKA
CCCCC
>Mature Secondary Structure
MVPFLRILGIETSCDETAAAVVERDAEGNARVLSDVVLSQLDEHSAYGGVVPEIAARAHV
CCCCEEHCCCCCCCHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHH
EALDELIEEALNRANVSLDEVDAIAATSGPGLIGGLLVGLMTGKAIARAAGKPLYAVNHL
HHHHHHHHHHHHHCCCCHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHCCCCEEEEECC
EGHALTARLTDGLAFPYLMLLVSGGHTQLILVRGVGEYQRWGTTIDDALGEAFDKTAKLL
CCCEEEEHHHCCHHHHHHHHHHCCCCEEEEEEECCCHHHHHCCCHHHHHHHHHHHHHHHH
GLPYPGGPAVERMARDGNPDRFAFPRPLVGEARLDFSFSGLKTAVRQAAQDIAPISDQDV
CCCCCCCHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCHH
ADICASFQKAISRTLKDRIGRGLQRFKTEFAATDEKPALVVAGGVAANLELRGTLQALCD
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEECCEEECEEHHHHHHHHHC
KNGFRFIAPPLHLCTDNAVMIAWAGLERMATGAAPDPLDVQPRSRWPLDSNAETLIGFGK
CCCCEEECCCHHHHCCCEEEEEECCHHHHHCCCCCCCCCCCCCCCCCCCCCCHHHEECCC
RGAKA
CCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA