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The map label for this gene is proA [H]

Identifier: 209551236

GI number: 209551236

Start: 3792655

End: 3793401

Strand: Reverse

Name: proA [H]

Synonym: Rleg2_3664

Alternate gene names: 209551236

Gene position: 3793401-3792655 (Counterclockwise)

Preceding gene: 209551237

Following gene: 209551235

Centisome position: 83.59

GC content: 60.78

Gene sequence:

>747_bases
ATGACCCATACGCCCGACATTCCGCGACCGTCCAAAGAACTGATCGACGCACTGAAGGAAATCGGCGCCGCGACGGTTGC
CGGCACGCTTGGCCACATGGGCTTCCGTAATCCGCACATGGTCGGTCCCGTGTCGCAGAATCCCGGAAAGTCGATCGTCG
GGCCGGCCCTGACGCTTCAATTCATGCCGCAGCGGCCGGACCTCTTCACCGAGGGAGAATATGCAGATCCGGAGACGCAG
TTGCACCGCCATGTGCTTTATCAGGTGCAGGAGGGCGATGTGGTCGTGGTCGACGCGCGCGGCGACATGAGCTCGGGCGT
CTTCGGCGATATGATGTCGACCTATTTCAAGGGTAGAGGCGGCGCCGGCATCGTGATCGATGGGTGCATGCGCGATCGGC
CGAATGTCGAAAAGCTGGATCTCCCTTTATGGCTGCGCGGCTGGACGCCCAACTATCATGTGCAGACCGGCATCTATCCC
AACGCCGTCAACGTTCCGATTGCCTGCGGCGGTGTCACGGTCATCCCTGGGGACATCATCGTCGCCGACGACGACGGGGT
GGTGATGCTTCCAGTCGCCATGGCCGCCAAGGTCATCGAAGAATCGCAAAAGCATCACGATTGGGAGGAGTTCTCGCGAG
TGAAACTGATGGGGGGCGGGTCGTTGCAGCGCTACTATCCGCTGCATGACGACGCCCGCGAAGAGTACGAGGAGTGGCGC
AAAACAAACCGCTTGGGAACCACTTAG

Upstream 100 bases:

>100_bases
GGCGATCAAGGCGGAGAGCTTTCGGTTCTGGGAAGCGCCGCATCTGAAGCGCCGCGACGGTTCTGTCACAAACTGGTAGT
TTCATCCACCGGAGCCTAAA

Downstream 100 bases:

>100_bases
CCATGGATTACCCTTAGTCTGGTGTTCTGAATCGCAGCGATAAACATTTGACGAAGGTCGAGAAAATGCAGCAGCCGTCC
ACCATGGCTTACAGCCTCAA

Product: hypothetical protein

Products: NA

Alternate protein names: 4-hydroxy-2-oxoglutarate aldolase [H]

Number of amino acids: Translated: 248; Mature: 247

Protein sequence:

>248_residues
MTHTPDIPRPSKELIDALKEIGAATVAGTLGHMGFRNPHMVGPVSQNPGKSIVGPALTLQFMPQRPDLFTEGEYADPETQ
LHRHVLYQVQEGDVVVVDARGDMSSGVFGDMMSTYFKGRGGAGIVIDGCMRDRPNVEKLDLPLWLRGWTPNYHVQTGIYP
NAVNVPIACGGVTVIPGDIIVADDDGVVMLPVAMAAKVIEESQKHHDWEEFSRVKLMGGGSLQRYYPLHDDAREEYEEWR
KTNRLGTT

Sequences:

>Translated_248_residues
MTHTPDIPRPSKELIDALKEIGAATVAGTLGHMGFRNPHMVGPVSQNPGKSIVGPALTLQFMPQRPDLFTEGEYADPETQ
LHRHVLYQVQEGDVVVVDARGDMSSGVFGDMMSTYFKGRGGAGIVIDGCMRDRPNVEKLDLPLWLRGWTPNYHVQTGIYP
NAVNVPIACGGVTVIPGDIIVADDDGVVMLPVAMAAKVIEESQKHHDWEEFSRVKLMGGGSLQRYYPLHDDAREEYEEWR
KTNRLGTT
>Mature_247_residues
THTPDIPRPSKELIDALKEIGAATVAGTLGHMGFRNPHMVGPVSQNPGKSIVGPALTLQFMPQRPDLFTEGEYADPETQL
HRHVLYQVQEGDVVVVDARGDMSSGVFGDMMSTYFKGRGGAGIVIDGCMRDRPNVEKLDLPLWLRGWTPNYHVQTGIYPN
AVNVPIACGGVTVIPGDIIVADDDGVVMLPVAMAAKVIEESQKHHDWEEFSRVKLMGGGSLQRYYPLHDDAREEYEEWRK
TNRLGTT

Specific function: Plays a role in protocatechuate degradation. Has a broad substrate specificity and catalyzes the aldol cleavage of 4- hydroxy-4-methyl-2-oxoglutarate, 4-hydroxy-2-oxoglutarate and 4- carboxy-4-hydroxy-2-oxoadipate, and the decarboxylation of oxaloacetate.

COG id: COG0684

COG function: function code H; Demethylmenaquinone methyltransferase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014165
- InterPro:   IPR005493 [H]

Pfam domain/function: PF03737 Methyltransf_6 [H]

EC number: =4.1.1.3; =4.1.3.16; =4.1.3.17 [H]

Molecular weight: Translated: 27350; Mature: 27219

Theoretical pI: Translated: 5.31; Mature: 5.31

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
4.4 %Met     (Translated Protein)
5.2 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
4.0 %Met     (Mature Protein)
4.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTHTPDIPRPSKELIDALKEIGAATVAGTLGHMGFRNPHMVGPVSQNPGKSIVGPALTLQ
CCCCCCCCCCHHHHHHHHHHHCHHHHHHHHHHCCCCCCCEECCCCCCCCCCCCCCEEEEE
FMPQRPDLFTEGEYADPETQLHRHVLYQVQEGDVVVVDARGDMSSGVFGDMMSTYFKGRG
ECCCCCCCCCCCCCCCHHHHHHHHHHEEECCCCEEEEECCCCCCCCHHHHHHHHHHCCCC
GAGIVIDGCMRDRPNVEKLDLPLWLRGWTPNYHVQTGIYPNAVNVPIACGGVTVIPGDII
CCEEEEECCCCCCCCCCEECCCEEEECCCCCEEEECCCCCCCCCCEEEECCEEEECCCEE
VADDDGVVMLPVAMAAKVIEESQKHHDWEEFSRVKLMGGGSLQRYYPLHDDAREEYEEWR
EECCCCEEEEHHHHHHHHHHHHHHCCCHHHHHEEEEECCCCCCEEECCCCHHHHHHHHHH
KTNRLGTT
HHCCCCCC
>Mature Secondary Structure 
THTPDIPRPSKELIDALKEIGAATVAGTLGHMGFRNPHMVGPVSQNPGKSIVGPALTLQ
CCCCCCCCCHHHHHHHHHHHCHHHHHHHHHHCCCCCCCEECCCCCCCCCCCCCCEEEEE
FMPQRPDLFTEGEYADPETQLHRHVLYQVQEGDVVVVDARGDMSSGVFGDMMSTYFKGRG
ECCCCCCCCCCCCCCCHHHHHHHHHHEEECCCCEEEEECCCCCCCCHHHHHHHHHHCCCC
GAGIVIDGCMRDRPNVEKLDLPLWLRGWTPNYHVQTGIYPNAVNVPIACGGVTVIPGDII
CCEEEEECCCCCCCCCCEECCCEEEECCCCCEEEECCCCCCCCCCEEEECCEEEECCCEE
VADDDGVVMLPVAMAAKVIEESQKHHDWEEFSRVKLMGGGSLQRYYPLHDDAREEYEEWR
EECCCCEEEEHHHHHHHHHHHHHHCCCHHHHHEEEEECCCCCCEEECCCCHHHHHHHHHH
KTNRLGTT
HHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11826967 [H]