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The map label for this gene is aroK

Identifier: 209551172

GI number: 209551172

Start: 3721906

End: 3722496

Strand: Reverse

Name: aroK

Synonym: Rleg2_3596

Alternate gene names: 209551172

Gene position: 3722496-3721906 (Counterclockwise)

Preceding gene: 209551179

Following gene: 209551171

Centisome position: 82.03

GC content: 62.27

Gene sequence:

>591_bases
ATGAGTGAACCACTGCTGACCGTTGCTGACAGCTTGAAAGACAGAGCTCGCGCCGCGCTCGGTTCACGCAATCTGATCCT
CGTCGGCCTGATGGGTGCGGGAAAATCCGCCGTCGGCCGCATCGTCGCCAGTCAGCTCGGCATTCCCTTCATCGACAGCG
ACCACGAAATAGAGCGCGTGTCGCGCATGACGATCCCCGAACTTTTCGCGGCCTATGGCGAGGACGAATTCCGGGCGCTG
GAAACGCGGGTGATGAAGCGGCTCTTAAAGGGCGGGCCGCGGGTCGTCTCCACCGGCGGCGGCGCCTTCATCAACGAGCG
GACGCGCAGGCATATCATCAAGGGCGGCGTCTCCGTCTGGCTGAAGGCCGATCTCGACGTGCTCTGGGAGCGGGTCAACA
AGCGCGACAACCGCCCCTTGCTCAAGACCGAAAACCCCAAGCAGACGCTCGAAGGCCTGATGAATGCGCGCTACCCGATC
TATGCGCAGGCCGACCTCACCGTGCTCTCGCGCGACGTGCGCAAGGAAATCATGGCCGACGAGGTGCTGAAGGCGATGAT
CGAAGCTCAGAAGGAAAGTGCAGCGTCATGA

Upstream 100 bases:

>100_bases
AGTGCAAGAAGCGGTATTCAAGCCATGATTCCCTTGTCCGCGACTTGACGCTCCAGCTGCATTTGTCGATACGGTTTGCA
AACAAAGTGTGAATGGACCG

Downstream 100 bases:

>100_bases
ATGCGATACCCTCCGCCTCATCAGTCCAGACGGTGCACGTGCCGCTCGGCGAGCGCGCCTACGATATCCTGATCGGGCCG
GGGCTGATCGCGCGGGCCGG

Product: shikimate kinase

Products: NA

Alternate protein names: SK

Number of amino acids: Translated: 196; Mature: 195

Protein sequence:

>196_residues
MSEPLLTVADSLKDRARAALGSRNLILVGLMGAGKSAVGRIVASQLGIPFIDSDHEIERVSRMTIPELFAAYGEDEFRAL
ETRVMKRLLKGGPRVVSTGGGAFINERTRRHIIKGGVSVWLKADLDVLWERVNKRDNRPLLKTENPKQTLEGLMNARYPI
YAQADLTVLSRDVRKEIMADEVLKAMIEAQKESAAS

Sequences:

>Translated_196_residues
MSEPLLTVADSLKDRARAALGSRNLILVGLMGAGKSAVGRIVASQLGIPFIDSDHEIERVSRMTIPELFAAYGEDEFRAL
ETRVMKRLLKGGPRVVSTGGGAFINERTRRHIIKGGVSVWLKADLDVLWERVNKRDNRPLLKTENPKQTLEGLMNARYPI
YAQADLTVLSRDVRKEIMADEVLKAMIEAQKESAAS
>Mature_195_residues
SEPLLTVADSLKDRARAALGSRNLILVGLMGAGKSAVGRIVASQLGIPFIDSDHEIERVSRMTIPELFAAYGEDEFRALE
TRVMKRLLKGGPRVVSTGGGAFINERTRRHIIKGGVSVWLKADLDVLWERVNKRDNRPLLKTENPKQTLEGLMNARYPIY
AQADLTVLSRDVRKEIMADEVLKAMIEAQKESAAS

Specific function: Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate

COG id: COG0703

COG function: function code E; Shikimate kinase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the shikimate kinase family

Homologues:

Organism=Escherichia coli, GI87082255, Length=169, Percent_Identity=37.2781065088757, Blast_Score=110, Evalue=9e-26,
Organism=Escherichia coli, GI1786587, Length=143, Percent_Identity=28.6713286713287, Blast_Score=61, Evalue=4e-11,

Paralogues:

None

Copy number: 140 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 200 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): AROK_RHILW (B5ZSI5)

Other databases:

- EMBL:   CP001191
- RefSeq:   YP_002283089.1
- ProteinModelPortal:   B5ZSI5
- SMR:   B5ZSI5
- GeneID:   6982357
- GenomeReviews:   CP001191_GR
- KEGG:   rlt:Rleg2_3596
- HOGENOM:   HBG335815
- OMA:   VIYLRAN
- ProtClustDB:   PRK13946
- GO:   GO:0005737
- HAMAP:   MF_00109
- InterPro:   IPR000623
- InterPro:   IPR023000
- PRINTS:   PR01100

Pfam domain/function: PF01202 SKI

EC number: =2.7.1.71

Molecular weight: Translated: 21713; Mature: 21581

Theoretical pI: Translated: 10.18; Mature: 10.18

Prosite motif: PS01128 SHIKIMATE_KINASE

Important sites: BINDING 54-54 BINDING 78-78 BINDING 100-100 BINDING 138-138 BINDING 157-157 BINDING 174-174

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSEPLLTVADSLKDRARAALGSRNLILVGLMGAGKSAVGRIVASQLGIPFIDSDHEIERV
CCCCHHHHHHHHHHHHHHHHCCCCEEEEEECCCCHHHHHHHHHHHCCCCCCCCCHHHHHH
SRMTIPELFAAYGEDEFRALETRVMKRLLKGGPRVVSTGGGAFINERTRRHIIKGGVSVW
HHHHHHHHHHHHCCHHHHHHHHHHHHHHHCCCCEEEECCCCCHHHHHHHHHHHHCCHHHE
LKADLDVLWERVNKRDNRPLLKTENPKQTLEGLMNARYPIYAQADLTVLSRDVRKEIMAD
EHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHCCCCEEECCHHHHHHHHHHHHHHHH
EVLKAMIEAQKESAAS
HHHHHHHHHHHHHCCC
>Mature Secondary Structure 
SEPLLTVADSLKDRARAALGSRNLILVGLMGAGKSAVGRIVASQLGIPFIDSDHEIERV
CCCHHHHHHHHHHHHHHHHCCCCEEEEEECCCCHHHHHHHHHHHCCCCCCCCCHHHHHH
SRMTIPELFAAYGEDEFRALETRVMKRLLKGGPRVVSTGGGAFINERTRRHIIKGGVSVW
HHHHHHHHHHHHCCHHHHHHHHHHHHHHHCCCCEEEECCCCCHHHHHHHHHHHHCCHHHE
LKADLDVLWERVNKRDNRPLLKTENPKQTLEGLMNARYPIYAQADLTVLSRDVRKEIMAD
EHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHCCCCEEECCHHHHHHHHHHHHHHHH
EVLKAMIEAQKESAAS
HHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA