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The map label for this gene is atoC [H]

Identifier: 209551145

GI number: 209551145

Start: 3698762

End: 3699121

Strand: Reverse

Name: atoC [H]

Synonym: Rleg2_3569

Alternate gene names: 209551145

Gene position: 3699121-3698762 (Counterclockwise)

Preceding gene: 209551146

Following gene: 209551140

Centisome position: 81.52

GC content: 60.56

Gene sequence:

>360_bases
ATGGCAAGAATTCTGATTACGGAAGACGAGGACTCCCTGCGGTCTTTCGTAGCCCGGGCGCTCAGGCTCGACGGTCACGA
GACCGATGAAGCCGCTGATGGCGCCGAGGGGCTGGAGAAGCTGAGGGACGGGTCCTACGATCTGCTGCTTTCGGATATCC
GCATGCCCGTAATGGACGGCATCGAACTCGCTCACCAGGCAAAAGACGCCTTTCCCGGCCTGAAGATCCTGCTGATGACC
GGCTACGCCGAGCAGCGCGAACGGGCCGACGATCTTGCTGAAAAGATCATCGACGTCGTCGCCAAACCTTTTGCACTTCC
CGATATCCGCAAGGCGGTCGCCAGAGCGCTCGTCGCCTGA

Upstream 100 bases:

>100_bases
CGGGTTGTTAACCATTCCGTCCATCGCTTCGGCATCTTTACCGATCGAAAAGGAAAGTCTGGTGATTTCCGTCGTGGGCT
GAAGACGGAGCAATGCACAT

Downstream 100 bases:

>100_bases
AGCATGACGGGGAAACGCCTGAGCCTGTCTCGGGCGACGTCATGCACAGTTTTGCGTGACACTGGCTTAGCGCGCCGCCG
CTCCACTCTACGGCGGCGTA

Product: response regulator receiver protein

Products: NA

Alternate protein names: Ornithine decarboxylase antizyme; Ornithine/arginine decarboxylase inhibitor [H]

Number of amino acids: Translated: 119; Mature: 118

Protein sequence:

>119_residues
MARILITEDEDSLRSFVARALRLDGHETDEAADGAEGLEKLRDGSYDLLLSDIRMPVMDGIELAHQAKDAFPGLKILLMT
GYAEQRERADDLAEKIIDVVAKPFALPDIRKAVARALVA

Sequences:

>Translated_119_residues
MARILITEDEDSLRSFVARALRLDGHETDEAADGAEGLEKLRDGSYDLLLSDIRMPVMDGIELAHQAKDAFPGLKILLMT
GYAEQRERADDLAEKIIDVVAKPFALPDIRKAVARALVA
>Mature_118_residues
ARILITEDEDSLRSFVARALRLDGHETDEAADGAEGLEKLRDGSYDLLLSDIRMPVMDGIELAHQAKDAFPGLKILLMTG
YAEQRERADDLAEKIIDVVAKPFALPDIRKAVARALVA

Specific function: Member of the two-component regulatory system AtoS/AtoC involved in the transcriptional regulation of the ato genes for acetoacetate metabolism. Also an inhibitor of polyamine biosynthesis [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 sigma-54 factor interaction domain [H]

Homologues:

Organism=Escherichia coli, GI1788550, Length=117, Percent_Identity=38.4615384615385, Blast_Score=74, Evalue=4e-15,
Organism=Escherichia coli, GI1790299, Length=111, Percent_Identity=36.9369369369369, Blast_Score=66, Evalue=7e-13,
Organism=Escherichia coli, GI1788713, Length=103, Percent_Identity=36.8932038834951, Blast_Score=64, Evalue=3e-12,
Organism=Escherichia coli, GI1790437, Length=114, Percent_Identity=29.8245614035088, Blast_Score=61, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR011006
- InterPro:   IPR020441
- InterPro:   IPR009057
- InterPro:   IPR002197
- InterPro:   IPR002078
- InterPro:   IPR001789 [H]

Pfam domain/function: PF02954 HTH_8; PF00072 Response_reg; PF00158 Sigma54_activat [H]

EC number: NA

Molecular weight: Translated: 13104; Mature: 12973

Theoretical pI: Translated: 4.48; Mature: 4.48

Prosite motif: PS50110 RESPONSE_REGULATORY

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MARILITEDEDSLRSFVARALRLDGHETDEAADGAEGLEKLRDGSYDLLLSDIRMPVMDG
CCEEEEECCHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHCCCHHHHHHHHHHHHHHH
IELAHQAKDAFPGLKILLMTGYAEQRERADDLAEKIIDVVAKPFALPDIRKAVARALVA
HHHHHHHHHHCCCCEEHHCCCCHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCC
>Mature Secondary Structure 
ARILITEDEDSLRSFVARALRLDGHETDEAADGAEGLEKLRDGSYDLLLSDIRMPVMDG
CEEEEECCHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHCCCHHHHHHHHHHHHHHH
IELAHQAKDAFPGLKILLMTGYAEQRERADDLAEKIIDVVAKPFALPDIRKAVARALVA
HHHHHHHHHHCCCCEEHHCCCCHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9097040; 9278503; 8346225 [H]