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The map label for this gene is tlpA [H]

Identifier: 209551140

GI number: 209551140

Start: 3691990

End: 3692652

Strand: Reverse

Name: tlpA [H]

Synonym: Rleg2_3564

Alternate gene names: 209551140

Gene position: 3692652-3691990 (Counterclockwise)

Preceding gene: 209551145

Following gene: 209551132

Centisome position: 81.37

GC content: 61.54

Gene sequence:

>663_bases
ATGACGACAAAGAAATCCCTCGGGCTGCCATCCGTGAAATGGATCGCGATAGCCGCCGTTGCGGGTGTCGTTGCCGGTGC
GGCAGCGGTATACGTGAAGGAGACGGGGATTGGCAATGGCGGCGGTGAAACGGCGTCAGTCGAATGCAAGCTGGCCCGGG
ATCGCATCGCCAGCGTCACACCGCTGATGAAGGGGCAGGTGGCCGCTATGGTCGCCGCCTATGAGCCACGCAAGCTGACG
GCGGTCTCCTTCAACGGGCCGGACGGCAAGCCGCTGACGCTCGATCATTTTGCCGGCAAGACCGTGCTCCTTAATCTCTG
GGCGACATGGTGCGTGCCCTGCCGCGAGGAGATGCCGGCGCTGAACGCGCTCGAAAAGGAAATGGGCAGCGACAAGTTCC
AGGTGGTGCCCGTCAATATCGACAGCGGCGACGACGAGAAGCCGAAGACCTTCCTGGCCGAGACCGGCGTCGATGCGCTG
CAGCTCTATCGCGACAATACAATTGCAGTGTTCAACAGCTTGAAGAAGGAGGGTCTCGCCATGGGGCTGCCGGTGACGCT
GTTAATCGACGACAAGGGATGCCTGATTTCGGCAATGAACGGGCCGGCTGCCTGGGACAGCGACGATGCCAAGGCCCTGA
TCAAGGGTGTGGTCGGTTCCTAA

Upstream 100 bases:

>100_bases
CCGGAAGCGAAACGCCCGCCCCACATCTGGTTTGAAGATTTGGTATCCGTGGTGTCGGCCATGAAGGTGCCCGCCTTGAA
TGCATGTCTTGGAGAATGAA

Downstream 100 bases:

>100_bases
GTAGCCCGTCAGAAGTCTCCGTCTCCTTTGATGAGAAAGACGCCCGCAAGCCCGATAAGGACGCAGCATTGCAGCAGGAA
CATTGGTGTTTCAGTCGACA

Product: redoxin

Products: NA

Alternate protein names: Cytochrome c biogenesis protein tlpA [H]

Number of amino acids: Translated: 220; Mature: 219

Protein sequence:

>220_residues
MTTKKSLGLPSVKWIAIAAVAGVVAGAAAVYVKETGIGNGGGETASVECKLARDRIASVTPLMKGQVAAMVAAYEPRKLT
AVSFNGPDGKPLTLDHFAGKTVLLNLWATWCVPCREEMPALNALEKEMGSDKFQVVPVNIDSGDDEKPKTFLAETGVDAL
QLYRDNTIAVFNSLKKEGLAMGLPVTLLIDDKGCLISAMNGPAAWDSDDAKALIKGVVGS

Sequences:

>Translated_220_residues
MTTKKSLGLPSVKWIAIAAVAGVVAGAAAVYVKETGIGNGGGETASVECKLARDRIASVTPLMKGQVAAMVAAYEPRKLT
AVSFNGPDGKPLTLDHFAGKTVLLNLWATWCVPCREEMPALNALEKEMGSDKFQVVPVNIDSGDDEKPKTFLAETGVDAL
QLYRDNTIAVFNSLKKEGLAMGLPVTLLIDDKGCLISAMNGPAAWDSDDAKALIKGVVGS
>Mature_219_residues
TTKKSLGLPSVKWIAIAAVAGVVAGAAAVYVKETGIGNGGGETASVECKLARDRIASVTPLMKGQVAAMVAAYEPRKLTA
VSFNGPDGKPLTLDHFAGKTVLLNLWATWCVPCREEMPALNALEKEMGSDKFQVVPVNIDSGDDEKPKTFLAETGVDALQ
LYRDNTIAVFNSLKKEGLAMGLPVTLLIDDKGCLISAMNGPAAWDSDDAKALIKGVVGS

Specific function: Involved in cytochrome aa3 assembly [H]

COG id: COG0526

COG function: function code OC; Thiol-disulfide isomerase and thioredoxins

Gene ontology:

Cell location: Cell membrane; Single-pass type II membrane protein; Periplasmic side [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 thioredoxin domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013740
- InterPro:   IPR005746
- InterPro:   IPR017936
- InterPro:   IPR012336
- InterPro:   IPR017937
- InterPro:   IPR012335 [H]

Pfam domain/function: PF08534 Redoxin [H]

EC number: NA

Molecular weight: Translated: 23063; Mature: 22932

Theoretical pI: Translated: 5.35; Mature: 5.35

Prosite motif: PS00194 THIOREDOXIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
5.0 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
4.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTTKKSLGLPSVKWIAIAAVAGVVAGAAAVYVKETGIGNGGGETASVECKLARDRIASVT
CCCCCCCCCCCHHHHHHHHHHHHHHHHEEEEEEECCCCCCCCCCEEEEEEEHHHHHHHHC
PLMKGQVAAMVAAYEPRKLTAVSFNGPDGKPLTLDHFAGKTVLLNLWATWCVPCREEMPA
HHHHCHHHHHEEECCCCEEEEEEECCCCCCCEEECCCCCCCCEEEHHHHHCCCCHHCCCH
LNALEKEMGSDKFQVVPVNIDSGDDEKPKTFLAETGVDALQLYRDNTIAVFNSLKKEGLA
HHHHHHHHCCCCEEEEEEEECCCCCCCCHHHHHHCCCHHHHHHCCCCHHHHHHHHHCCEE
MGLPVTLLIDDKGCLISAMNGPAAWDSDDAKALIKGVVGS
ECCCEEEEECCCCCEEEECCCCCCCCCCHHHHHHHHHCCC
>Mature Secondary Structure 
TTKKSLGLPSVKWIAIAAVAGVVAGAAAVYVKETGIGNGGGETASVECKLARDRIASVT
CCCCCCCCCCHHHHHHHHHHHHHHHHEEEEEEECCCCCCCCCCEEEEEEEHHHHHHHHC
PLMKGQVAAMVAAYEPRKLTAVSFNGPDGKPLTLDHFAGKTVLLNLWATWCVPCREEMPA
HHHHCHHHHHEEECCCCEEEEEEECCCCCCCEEECCCCCCCCEEEHHHHHCCCCHHCCCH
LNALEKEMGSDKFQVVPVNIDSGDDEKPKTFLAETGVDALQLYRDNTIAVFNSLKKEGLA
HHHHHHHHCCCCEEEEEEEECCCCCCCCHHHHHHCCCHHHHHHCCCCHHHHHHHHHCCEE
MGLPVTLLIDDKGCLISAMNGPAAWDSDDAKALIKGVVGS
ECCCEEEEECCCCCEEEECCCCCCCCCCHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 8253065; 12597275 [H]