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The map label for this gene is chaA [C]

Identifier: 209551087

GI number: 209551087

Start: 3629270

End: 3630403

Strand: Direct

Name: chaA [C]

Synonym: Rleg2_3511

Alternate gene names: 209551087

Gene position: 3629270-3630403 (Clockwise)

Preceding gene: 209551086

Following gene: 209551088

Centisome position: 79.98

GC content: 59.88

Gene sequence:

>1134_bases
ATGACGGACGATCCCGCATTGCGTGCCGTCAGCGCCGCCAGCCTGTTGCGCGAGGAATGGTTCCTGGGCGTCAGCGTCGC
GACAAGCTTCGCATTTCTTGCTTTCCAGGAGCAGCTCTTCGGCCGGCTTTCCGATCCGCTTTGGTTCACTGTCGTTTTCG
GGTGGCTGTTTGCCGTCGTGCTCGGCTCCGCTCTATCGGTCGTGCGGCACGCAGACCACCTGGCGGAGCGGCTGAAGGAG
CCTTACGGCACGCTCATTCTAACCCTTTCAATCACGTCGATCGAGGTGATGGCAATATCGGCCGTCATGCTTCACGGCGA
AAACAATCCCACGCTGGCGCGCGACACGCTGTTTGCAGTCGTCATGATCATTTTGAACGGCATGGTCGGCCTGTCATTGC
TGCTCGGCGCGTGGCGGCGACCGGAACAGCAGCACAACCTGCAGGGCGCCAACGCCTATCTCGGAGTAATCGTGCCGCTG
GCGACGCTCAGCCTAGTCATGCCGACATTTCTGGCAGGTCCGGACGGACAGCATCCATCGGCACCGAGACAACTGATACT
GGGCGTCATATCGGTCGGACTTTATTCCACGTTTCTGTTTCTTCAGGCCGGCCGCCATCGGGACTATTTCGCGGACGACG
GCAACCGTCAGCAACCTCGCAGCGAACATGTCGCTGGCCATGGGCCGATCTGGCCGCATGCCATCCTGCTCGTCACCTAT
ATGGCTCCCGTCGTGTTCCTGGTCGAACAGCTTGCGCGGCCGATCGATTACATTATCGAAACCCTGCATGCTCCAACCGC
ATTTGGCGGTGTCGTGATGGCTATCCTCGTCGCCACGCCTGAGGCAATCAGCGCCGTGCGCGCGTCTATCGCCAACAATC
TTCAGCGCTCCGTAAACATTTTCCTCGGTTCGGTATTGTCGACGATCGGGCTGACGGTGCCGGCGATGCTTGTTGTCAGC
CAGCTCTACGGACACAGCGTGACGCTCGGCCTGGAGCACGGAGATCTGGTGATGCTCCTGCTCACGCTTGCCGTCAGCAT
CATTACCTTCGCCAGCGGCCGCACGCATCTCATGCAAGGTGCAGTCCATCTGGTGCTTTTCCTGGCCTACGTGCTGCTCA
TTTTCCAGCAGTGA

Upstream 100 bases:

>100_bases
ACGCGCTTTAGGCTCAGGTGGCGGGCAAGAGACAGCGGGCGGACACGATGGTGGTGATGATCGCATGGCGGCGGCATTTG
CCCGAAGGCGGGTGGTTTCG

Downstream 100 bases:

>100_bases
TCTCCGGCGGCGTGAGATCAGGAAAGTAAAAAACTCCACGCTCTGCCTTTCTTCCGCTATGGTGACAGTAACGATCGCAC
CACTTGCAAGCCTCGCGGCG

Product: sodium/calcium exchanger membrane protein

Products: Na (I) [Periplasm]; Ca (II) [Periplasm]; Proton [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 377; Mature: 376

Protein sequence:

>377_residues
MTDDPALRAVSAASLLREEWFLGVSVATSFAFLAFQEQLFGRLSDPLWFTVVFGWLFAVVLGSALSVVRHADHLAERLKE
PYGTLILTLSITSIEVMAISAVMLHGENNPTLARDTLFAVVMIILNGMVGLSLLLGAWRRPEQQHNLQGANAYLGVIVPL
ATLSLVMPTFLAGPDGQHPSAPRQLILGVISVGLYSTFLFLQAGRHRDYFADDGNRQQPRSEHVAGHGPIWPHAILLVTY
MAPVVFLVEQLARPIDYIIETLHAPTAFGGVVMAILVATPEAISAVRASIANNLQRSVNIFLGSVLSTIGLTVPAMLVVS
QLYGHSVTLGLEHGDLVMLLLTLAVSIITFASGRTHLMQGAVHLVLFLAYVLLIFQQ

Sequences:

>Translated_377_residues
MTDDPALRAVSAASLLREEWFLGVSVATSFAFLAFQEQLFGRLSDPLWFTVVFGWLFAVVLGSALSVVRHADHLAERLKE
PYGTLILTLSITSIEVMAISAVMLHGENNPTLARDTLFAVVMIILNGMVGLSLLLGAWRRPEQQHNLQGANAYLGVIVPL
ATLSLVMPTFLAGPDGQHPSAPRQLILGVISVGLYSTFLFLQAGRHRDYFADDGNRQQPRSEHVAGHGPIWPHAILLVTY
MAPVVFLVEQLARPIDYIIETLHAPTAFGGVVMAILVATPEAISAVRASIANNLQRSVNIFLGSVLSTIGLTVPAMLVVS
QLYGHSVTLGLEHGDLVMLLLTLAVSIITFASGRTHLMQGAVHLVLFLAYVLLIFQQ
>Mature_376_residues
TDDPALRAVSAASLLREEWFLGVSVATSFAFLAFQEQLFGRLSDPLWFTVVFGWLFAVVLGSALSVVRHADHLAERLKEP
YGTLILTLSITSIEVMAISAVMLHGENNPTLARDTLFAVVMIILNGMVGLSLLLGAWRRPEQQHNLQGANAYLGVIVPLA
TLSLVMPTFLAGPDGQHPSAPRQLILGVISVGLYSTFLFLQAGRHRDYFADDGNRQQPRSEHVAGHGPIWPHAILLVTYM
APVVFLVEQLARPIDYIIETLHAPTAFGGVVMAILVATPEAISAVRASIANNLQRSVNIFLGSVLSTIGLTVPAMLVVSQ
LYGHSVTLGLEHGDLVMLLLTLAVSIITFASGRTHLMQGAVHLVLFLAYVLLIFQQ

Specific function: Possible cation transporter [H]

COG id: COG0387

COG function: function code P; Ca2+/H+ antiporter

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the sodium/potassium/calcium exchanger family [H]

Homologues:

Organism=Escherichia coli, GI1787468, Length=320, Percent_Identity=39.0625, Blast_Score=226, Evalue=3e-60,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004713
- InterPro:   IPR004837 [H]

Pfam domain/function: PF01699 Na_Ca_ex [H]

EC number: NA

Molecular weight: Translated: 40854; Mature: 40722

Theoretical pI: Translated: 6.63; Mature: 6.63

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTDDPALRAVSAASLLREEWFLGVSVATSFAFLAFQEQLFGRLSDPLWFTVVFGWLFAVV
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHH
LGSALSVVRHADHLAERLKEPYGTLILTLSITSIEVMAISAVMLHGENNPTLARDTLFAV
HHHHHHHHHHHHHHHHHHHCCCCEEEEEEEHHHHHHHHHHHHHEECCCCCCHHHHHHHHH
VMIILNGMVGLSLLLGAWRRPEQQHNLQGANAYLGVIVPLATLSLVMPTFLAGPDGQHPS
HHHHHHHHHHHHHHHHHHCCCCHHHCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCC
APRQLILGVISVGLYSTFLFLQAGRHRDYFADDGNRQQPRSEHVAGHGPIWPHAILLVTY
HHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCHHCCCCCCCCHHHHHHHHHH
MAPVVFLVEQLARPIDYIIETLHAPTAFGGVVMAILVATPEAISAVRASIANNLQRSVNI
HHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHH
FLGSVLSTIGLTVPAMLVVSQLYGHSVTLGLEHGDLVMLLLTLAVSIITFASGRTHLMQG
HHHHHHHHHHHHHHHHHHHHHHHCCEEEEECCCCHHHHHHHHHHHHHHHHCCCHHHHHHH
AVHLVLFLAYVLLIFQQ
HHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
TDDPALRAVSAASLLREEWFLGVSVATSFAFLAFQEQLFGRLSDPLWFTVVFGWLFAVV
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHH
LGSALSVVRHADHLAERLKEPYGTLILTLSITSIEVMAISAVMLHGENNPTLARDTLFAV
HHHHHHHHHHHHHHHHHHHCCCCEEEEEEEHHHHHHHHHHHHHEECCCCCCHHHHHHHHH
VMIILNGMVGLSLLLGAWRRPEQQHNLQGANAYLGVIVPLATLSLVMPTFLAGPDGQHPS
HHHHHHHHHHHHHHHHHHCCCCHHHCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCC
APRQLILGVISVGLYSTFLFLQAGRHRDYFADDGNRQQPRSEHVAGHGPIWPHAILLVTY
HHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCHHCCCCCCCCHHHHHHHHHH
MAPVVFLVEQLARPIDYIIETLHAPTAFGGVVMAILVATPEAISAVRASIANNLQRSVNI
HHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHH
FLGSVLSTIGLTVPAMLVVSQLYGHSVTLGLEHGDLVMLLLTLAVSIITFASGRTHLMQG
HHHHHHHHHHHHHHHHHHHHHHHCCEEEEECCCCHHHHHHHHHHHHHHHHCCCHHHHHHH
AVHLVLFLAYVLLIFQQ
HHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Na (I) [Cytoplasm]; Proton [Periplasm]; Ca (II) [Cytoplasm]; Proton [Periplasm] [C]

Specific reaction: Na (I) [Cytoplasm] + Proton [Periplasm] = Proton [Cytoplasm] + Na (I) [Periplasm] Ca (II) [Cytoplasm] + Proton [Periplasm] = Ca (II) [Periplasm] + Proton [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9163424 [H]