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The map label for this gene is queE [H]

Identifier: 209551071

GI number: 209551071

Start: 3612176

End: 3612904

Strand: Direct

Name: queE [H]

Synonym: Rleg2_3495

Alternate gene names: 209551071

Gene position: 3612176-3612904 (Clockwise)

Preceding gene: 209551070

Following gene: 209551078

Centisome position: 79.6

GC content: 63.51

Gene sequence:

>729_bases
GTGAGCGGAGAGACCATTCGCATCAGCGAGATCTTCGGCCCGACCATACAGGGCGAAGGCGCGTTGATCGGGCTGCCGAC
AGTGTTCGTCAGGACAGGCGGCTGTGACTATCGCTGTTCCTGGTGCGACAGCCTGCATGCGGTCGACAGCGCCTTTCGGG
ATCAATGGCTTCCGATGTCCGTCGAGGCGGTCTGGCAGCAGGTCACAAAGCTCTCCGGCGGCAGGCCTCTGACGGTTTCC
CTTTCCGGAGGCAATCCCGCGATCCAGCCGCTCGGGCCATTGATCGAATTCGGGCATTCGCAAGGATACCGTTTCGCCCT
GGAAACGCAGGGGAGCGTCGCCCGGGACTGGTTTCGCGATCTCGACATGCTGGTTTTGAGCCCCAAGCCGCCGTCGAGCG
GAATGCTGACGGATTGGGATGAGGTCGACAACTGTCTCCGGCTCGCCGCCGGCGGGCCGGACATCGTCTTGAAAATCGTC
GTCTTCGATGATGCCGACTATGCCTTCGCCCGGGAGGCGGGCGAGCGCTATCCCGCTATTCCCCTGTTCCTTCAGCCGGG
CAACCATACACCGCCGCCGCCCGATGACGACGATGCCCGCATCGATATCGACGGCGTAATGGACCGGATGCACTGGCTCG
TCGAGAAGGTGACGGCCGATCGGTGGTATGCGCCGCGGGTGCTGCCGCAGCTGCACGTGCTGCTGTGGGGCAACAAACGC
GGTGTCTGA

Upstream 100 bases:

>100_bases
TCCTGGCAAAGCATTTCTACGACTGGTGCAAAGAGCGTTTCCCGGAGACATCCTCCGTCCGCATCAGCGAGACACCGAAG
ACCTGGGCGGAGTATCGGCC

Downstream 100 bases:

>100_bases
CCCCACCTAAGCCTACCGCTCCGGAAAAGCGAAGACATCGACCGGCTCTCCGAGCCCGCGCAGCGGGAAGGTGCCGAGAC
TGTCCATGTCTTTGGCGCAG

Product: 7-cyano-7-deazaguanosine (preQ0) biosynthesis protein QueE

Products: NA

Alternate protein names: CDG synthase; Queuosine biosynthesis protein queE [H]

Number of amino acids: Translated: 242; Mature: 241

Protein sequence:

>242_residues
MSGETIRISEIFGPTIQGEGALIGLPTVFVRTGGCDYRCSWCDSLHAVDSAFRDQWLPMSVEAVWQQVTKLSGGRPLTVS
LSGGNPAIQPLGPLIEFGHSQGYRFALETQGSVARDWFRDLDMLVLSPKPPSSGMLTDWDEVDNCLRLAAGGPDIVLKIV
VFDDADYAFAREAGERYPAIPLFLQPGNHTPPPPDDDDARIDIDGVMDRMHWLVEKVTADRWYAPRVLPQLHVLLWGNKR
GV

Sequences:

>Translated_242_residues
MSGETIRISEIFGPTIQGEGALIGLPTVFVRTGGCDYRCSWCDSLHAVDSAFRDQWLPMSVEAVWQQVTKLSGGRPLTVS
LSGGNPAIQPLGPLIEFGHSQGYRFALETQGSVARDWFRDLDMLVLSPKPPSSGMLTDWDEVDNCLRLAAGGPDIVLKIV
VFDDADYAFAREAGERYPAIPLFLQPGNHTPPPPDDDDARIDIDGVMDRMHWLVEKVTADRWYAPRVLPQLHVLLWGNKR
GV
>Mature_241_residues
SGETIRISEIFGPTIQGEGALIGLPTVFVRTGGCDYRCSWCDSLHAVDSAFRDQWLPMSVEAVWQQVTKLSGGRPLTVSL
SGGNPAIQPLGPLIEFGHSQGYRFALETQGSVARDWFRDLDMLVLSPKPPSSGMLTDWDEVDNCLRLAAGGPDIVLKIVV
FDDADYAFAREAGERYPAIPLFLQPGNHTPPPPDDDDARIDIDGVMDRMHWLVEKVTADRWYAPRVLPQLHVLLWGNKRG
V

Specific function: Catalyzes the conversion of 6-carboxy-5,6,7,8- tetrahydropterin (CPH4) to 7-carboxy-7-deazaguanine (CDG) [H]

COG id: COG0602

COG function: function code O; Organic radical activating enzymes

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the radical SAM superfamily. 7-carboxy-7- deazaguanine synthase family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017742
- InterPro:   IPR007197 [H]

Pfam domain/function: PF04055 Radical_SAM [H]

EC number: NA

Molecular weight: Translated: 26757; Mature: 26625

Theoretical pI: Translated: 4.61; Mature: 4.61

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSGETIRISEIFGPTIQGEGALIGLPTVFVRTGGCDYRCSWCDSLHAVDSAFRDQWLPMS
CCCCEEEEEECCCCCCCCCCCEEECCEEEEEECCCCEEEHHHHHHHHHHHHHHHCCCCCC
VEAVWQQVTKLSGGRPLTVSLSGGNPAIQPLGPLIEFGHSQGYRFALETQGSVARDWFRD
HHHHHHHHHHHCCCCEEEEEECCCCCCCCCCHHHHHCCCCCCEEEEEECCCCHHHHHHHC
LDMLVLSPKPPSSGMLTDWDEVDNCLRLAAGGPDIVLKIVVFDDADYAFAREAGERYPAI
CCEEEECCCCCCCCCCCCHHHHHHHHHHCCCCCCEEEEEEEECCCCHHHHHHHCCCCCCE
PLFLQPGNHTPPPPDDDDARIDIDGVMDRMHWLVEKVTADRWYAPRVLPQLHVLLWGNKR
EEEECCCCCCCCCCCCCCCEEEHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEEEECCCC
GV
CC
>Mature Secondary Structure 
SGETIRISEIFGPTIQGEGALIGLPTVFVRTGGCDYRCSWCDSLHAVDSAFRDQWLPMS
CCCEEEEEECCCCCCCCCCCEEECCEEEEEECCCCEEEHHHHHHHHHHHHHHHCCCCCC
VEAVWQQVTKLSGGRPLTVSLSGGNPAIQPLGPLIEFGHSQGYRFALETQGSVARDWFRD
HHHHHHHHHHHCCCCEEEEEECCCCCCCCCCHHHHHCCCCCCEEEEEECCCCHHHHHHHC
LDMLVLSPKPPSSGMLTDWDEVDNCLRLAAGGPDIVLKIVVFDDADYAFAREAGERYPAI
CCEEEECCCCCCCCCCCCHHHHHHHHHHCCCCCCEEEEEEEECCCCHHHHHHHCCCCCCE
PLFLQPGNHTPPPPDDDDARIDIDGVMDRMHWLVEKVTADRWYAPRVLPQLHVLLWGNKR
EEEECCCCCCCCCCCCCCCEEEHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEEEECCCC
GV
CC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]