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The map label for this gene is zntR [H]

Identifier: 209551078

GI number: 209551078

Start: 3621226

End: 3621648

Strand: Direct

Name: zntR [H]

Synonym: Rleg2_3502

Alternate gene names: 209551078

Gene position: 3621226-3621648 (Clockwise)

Preceding gene: 209551071

Following gene: 209551079

Centisome position: 79.8

GC content: 62.65

Gene sequence:

>423_bases
ATGAAAAAGATCACGATCGGTGAAGCGGCTCGCCAGAGCGGGGTCAAAGTGCCGACGGTGCGTTATTATGAGAGCATCGG
ACTGCTCGCGGCGCCGAGCCGCAGCGAAGGCAATCAGCGCTCCTTCGAACCTGCTGATATCAGCCGCCTTGCCTTCATCC
GCCATGCCCGCGAACTCGGCTTCGAGATCGAGGCGATCCGCACGCTGCTGACCCTGCAGGATGATCCGCACCAATCCTGC
GCCTCCGCCGATGCCATCGCCAAGGCTCGTCTCGTCGAAGTCGAGCAGCGCATCCGCAGCCTGATGGCTTTGAAGGCCGA
GCTGGAAACCATGGTGGAAGGCTGCGGCCACGGCCGCGTCGACCAATGCCGTGTCATCGAGGTTCTCGCCGACCACGGCC
AGTGCACGCATTCGCATCACTGA

Upstream 100 bases:

>100_bases
CGGTATCGTGTCTCGCTCGTCTCAGCCATGATCCGCTTCCTTGTCAAACAGAAGCATCCCTCCTACATCCTCTAGCGACT
AGAGGTGCAAGAGGAAAATC

Downstream 100 bases:

>100_bases
TCCCGCCCTTGCAGGCAAGGCGCAGCCGCGCCAAAACGGCACCAGAAAGAATCGGGCAAAGACATCCATGAGCCAGAAGC
GAATTGCCATCATCGGCGGC

Product: MerR family transcriptional regulator

Products: NA

Alternate protein names: Zn(II)-responsive regulator of zntA [H]

Number of amino acids: Translated: 140; Mature: 140

Protein sequence:

>140_residues
MKKITIGEAARQSGVKVPTVRYYESIGLLAAPSRSEGNQRSFEPADISRLAFIRHARELGFEIEAIRTLLTLQDDPHQSC
ASADAIAKARLVEVEQRIRSLMALKAELETMVEGCGHGRVDQCRVIEVLADHGQCTHSHH

Sequences:

>Translated_140_residues
MKKITIGEAARQSGVKVPTVRYYESIGLLAAPSRSEGNQRSFEPADISRLAFIRHARELGFEIEAIRTLLTLQDDPHQSC
ASADAIAKARLVEVEQRIRSLMALKAELETMVEGCGHGRVDQCRVIEVLADHGQCTHSHH
>Mature_140_residues
MKKITIGEAARQSGVKVPTVRYYESIGLLAAPSRSEGNQRSFEPADISRLAFIRHARELGFEIEAIRTLLTLQDDPHQSC
ASADAIAKARLVEVEQRIRSLMALKAELETMVEGCGHGRVDQCRVIEVLADHGQCTHSHH

Specific function: Zinc-responsive transcriptional regulator of zntA [H]

COG id: COG0789

COG function: function code K; Predicted transcriptional regulators

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH merR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1789687, Length=128, Percent_Identity=39.84375, Blast_Score=94, Evalue=3e-21,
Organism=Escherichia coli, GI1786695, Length=134, Percent_Identity=28.3582089552239, Blast_Score=74, Evalue=4e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR009061
- InterPro:   IPR000551
- InterPro:   IPR015358
- InterPro:   IPR011788 [H]

Pfam domain/function: PF00376 MerR; PF09278 MerR-DNA-bind [H]

EC number: NA

Molecular weight: Translated: 15502; Mature: 15502

Theoretical pI: Translated: 7.18; Mature: 7.18

Prosite motif: PS00552 HTH_MERR_1 ; PS50937 HTH_MERR_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.9 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
5.0 %Cys+Met (Translated Protein)
2.9 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
5.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKITIGEAARQSGVKVPTVRYYESIGLLAAPSRSEGNQRSFEPADISRLAFIRHARELG
CCCCCCCHHHHHCCCCCCHHHHHHHCCCEECCCCCCCCCCCCCCHHHHHHHHHHHHHHHC
FEIEAIRTLLTLQDDPHQSCASADAIAKARLVEVEQRIRSLMALKAELETMVEGCGHGRV
CHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
DQCRVIEVLADHGQCTHSHH
CHHHHHHHHHHCCCCCCCCC
>Mature Secondary Structure
MKKITIGEAARQSGVKVPTVRYYESIGLLAAPSRSEGNQRSFEPADISRLAFIRHARELG
CCCCCCCHHHHHCCCCCCHHHHHHHCCCEECCCCCCCCCCCCCCHHHHHHHHHHHHHHHC
FEIEAIRTLLTLQDDPHQSCASADAIAKARLVEVEQRIRSLMALKAELETMVEGCGHGRV
CHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
DQCRVIEVLADHGQCTHSHH
CHHHHHHHHHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]