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The map label for this gene is queC [H]

Identifier: 209551069

GI number: 209551069

Start: 3611113

End: 3611823

Strand: Direct

Name: queC [H]

Synonym: Rleg2_3493

Alternate gene names: 209551069

Gene position: 3611113-3611823 (Clockwise)

Preceding gene: 209551068

Following gene: 209551070

Centisome position: 79.58

GC content: 62.31

Gene sequence:

>711_bases
ATGAGAACCATCGTCGTCTGCTCCGGCGGACTCGACTCCGTTTCGCTTGCCCACAAGATAGCAGCGGAACAACAGCTTAT
TGGCCTCGTCTCCTTCGACTACGGCCAGCGGCATCGCAAGGAACTCGATTTCGCCGCCCGGTGCGCCGCGCGCCTCGCCG
TTCCCCATCATATCATCGATATATCAGCCATCGGCGGCCATCTCAGCGGATCGGCCCTGACCGACGACATCGAGGTTCCG
GACGGCCATTATGCCGAGGAGACCATGAAGGCCACCGTGGTGCCGAACCGCAACGCCATCATGCTGGCCATCGCATTCGG
CCTGGCGGCCGCGCAGAAGGCGGATGCCGTTGCCGTCGCCGTGCATGGCGGCGACCACTTCATCTACCCCGACTGCCGGC
CGGGCTTCATCGACGCCTTCCAGCGCATGCAGAACGAGGCGCTGGACGGTTATGCCAGCGTCAGGCTGCTTGCCCCCTAT
GTCGAAGTGTCGAAAGCGGCGATCGTTACCGACGGCGAAAAACATGCGACGCCGTTTGCGGAAACATGGTCCTGCTACAA
GGGCGGCCGGCTCCATTGCGGGCGCTGCGGAACTTGCGTCGAACGCCGCGAGGCTTTCCATCTCGCCGGTATTCCGGATC
CGACGGAATATGAAGACCAGGATTTCTGGAAAGCGGCGGTGTCGCAATATTCTGCTGCGGAGGTGCGTTGA

Upstream 100 bases:

>100_bases
GGTCGGTTAAGCCCAGGCTATTCCCAACAGGCGTTATTTGCCCTAGAAGCACGCCGTAATCCGGTCGCAGCCCACCCGGT
CAAAACAAGGGATCCAAAAT

Downstream 100 bases:

>100_bases
TGTACCGCATCACCAAGGAGTTCCATCTCTCCGCCTCGCACCAGCTGGATCATCTGCCGGCCGACCATCAATGCGCCAGG
CTGCACGGCCACAACTACAT

Product: exsB protein

Products: NA

Alternate protein names: 7-cyano-7-carbaguanine synthase; PreQ(0) synthase; Queuosine biosynthesis protein queC [H]

Number of amino acids: Translated: 236; Mature: 236

Protein sequence:

>236_residues
MRTIVVCSGGLDSVSLAHKIAAEQQLIGLVSFDYGQRHRKELDFAARCAARLAVPHHIIDISAIGGHLSGSALTDDIEVP
DGHYAEETMKATVVPNRNAIMLAIAFGLAAAQKADAVAVAVHGGDHFIYPDCRPGFIDAFQRMQNEALDGYASVRLLAPY
VEVSKAAIVTDGEKHATPFAETWSCYKGGRLHCGRCGTCVERREAFHLAGIPDPTEYEDQDFWKAAVSQYSAAEVR

Sequences:

>Translated_236_residues
MRTIVVCSGGLDSVSLAHKIAAEQQLIGLVSFDYGQRHRKELDFAARCAARLAVPHHIIDISAIGGHLSGSALTDDIEVP
DGHYAEETMKATVVPNRNAIMLAIAFGLAAAQKADAVAVAVHGGDHFIYPDCRPGFIDAFQRMQNEALDGYASVRLLAPY
VEVSKAAIVTDGEKHATPFAETWSCYKGGRLHCGRCGTCVERREAFHLAGIPDPTEYEDQDFWKAAVSQYSAAEVR
>Mature_236_residues
MRTIVVCSGGLDSVSLAHKIAAEQQLIGLVSFDYGQRHRKELDFAARCAARLAVPHHIIDISAIGGHLSGSALTDDIEVP
DGHYAEETMKATVVPNRNAIMLAIAFGLAAAQKADAVAVAVHGGDHFIYPDCRPGFIDAFQRMQNEALDGYASVRLLAPY
VEVSKAAIVTDGEKHATPFAETWSCYKGGRLHCGRCGTCVERREAFHLAGIPDPTEYEDQDFWKAAVSQYSAAEVR

Specific function: Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)) [H]

COG id: COG0603

COG function: function code R; Predicted PP-loop superfamily ATPase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the queC family [H]

Homologues:

Organism=Escherichia coli, GI1786648, Length=212, Percent_Identity=33.9622641509434, Blast_Score=95, Evalue=3e-21,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR018317
- InterPro:   IPR014729 [H]

Pfam domain/function: PF06508 ExsB [H]

EC number: NA

Molecular weight: Translated: 25542; Mature: 25542

Theoretical pI: Translated: 6.11; Mature: 6.11

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.0 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
3.0 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRTIVVCSGGLDSVSLAHKIAAEQQLIGLVSFDYGQRHRKELDFAARCAARLAVPHHIID
CCEEEEECCCCCHHHHHHHHHHHHHHHHEEECCCCHHHHHHHHHHHHHHHHHCCCHHEEE
ISAIGGHLSGSALTDDIEVPDGHYAEETMKATVVPNRNAIMLAIAFGLAAAQKADAVAVA
EEECCCCCCCCCCCCCCCCCCCCCHHHHEEEEECCCCCEEEEEEEHHHHHHCCCCEEEEE
VHGGDHFIYPDCRPGFIDAFQRMQNEALDGYASVRLLAPYVEVSKAAIVTDGEKHATPFA
EECCCEEECCCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCEEEEECCHHHCCCCH
ETWSCYKGGRLHCGRCGTCVERREAFHLAGIPDPTEYEDQDFWKAAVSQYSAAEVR
HHHHHCCCCCEECCCCCHHHHHHHHEEECCCCCCCCCCCHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MRTIVVCSGGLDSVSLAHKIAAEQQLIGLVSFDYGQRHRKELDFAARCAARLAVPHHIID
CCEEEEECCCCCHHHHHHHHHHHHHHHHEEECCCCHHHHHHHHHHHHHHHHHCCCHHEEE
ISAIGGHLSGSALTDDIEVPDGHYAEETMKATVVPNRNAIMLAIAFGLAAAQKADAVAVA
EEECCCCCCCCCCCCCCCCCCCCCHHHHEEEEECCCCCEEEEEEEHHHHHHCCCCEEEEE
VHGGDHFIYPDCRPGFIDAFQRMQNEALDGYASVRLLAPYVEVSKAAIVTDGEKHATPFA
EECCCEEECCCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCEEEEECCHHHCCCCH
ETWSCYKGGRLHCGRCGTCVERREAFHLAGIPDPTEYEDQDFWKAAVSQYSAAEVR
HHHHHCCCCCEECCCCCHHHHHHHHEEECCCCCCCCCCCHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA