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The map label for this gene is celR [H]

Identifier: 209551068

GI number: 209551068

Start: 3609970

End: 3611022

Strand: Direct

Name: celR [H]

Synonym: Rleg2_3492

Alternate gene names: 209551068

Gene position: 3609970-3611022 (Clockwise)

Preceding gene: 209551063

Following gene: 209551069

Centisome position: 79.55

GC content: 63.72

Gene sequence:

>1053_bases
GTGACCGAACCGTCCCGGCCGCGAAGCGGCGAAAATCTCGAGATCACGCATAAGCGCGGCAAGCCGACCTTGCGAACGAT
CGCCACGATCGCCGGCCTTGCCGTGACGACGGTGTCGCGGGCGCTCTCCGATGCACCGCAGATTTCGCTGGAGACCCGCC
AGCGCGTGCACCGCATTGCCCGCGAGATCGGCTATCTCCCCGATCGGGCCGCGCAGCGCCTGAAGACCGGCCGCACCAAT
GTCATCGCCATCCTGCTCGATTCGCACGAGGAAGTCGTCGGTTTCAGCACCTCGATCATGTACGGCATTGCCAAGGCGCT
GAAGGAGACTTCCTACCATCTCGTCGTCGCCCCGAACTTCCTGTCGACCACCGATGTCGAGGCCGCCGAATATATCGTCC
GCAACCACCTCGCCGACGGGCTGATCTTCACGCGAACCGAACCGCTCGATGCCCGCGTCCGCCTGCTGCTCGAAACCGGC
TTTCCCTTCATCTGCCACGGCCGCACGGAATTTTCGACGCCGCACCCTTATGTCGACTACGACAATTTCACCTTTGCCTA
TGAGGCGACGCGCCGGCTGATCGCAAAGGACCGCAAGAAGGTGGCCGTGGTCCTGCCGCCGAAACGGCTGACCTTCTGCC
AGCATATCCTGCACGGCTTCATGACGGCGGTGCGGGAGGCGGGCATTGCCTATGAGATCCCCGAAACGGTCGATCTCGAT
ACGCCGGCGGATGCGCTGCGCGATTTCATCTCCAGCCGCGCCGCCGCTCCGGAAGCGCCCGATGGTTTCATCTGTCCCGG
CGAAGTCTCCGCACTCGCCGTCATCAGCGGCATGAGCGACGCCGGCCGGACACTCGCGGTCGATTACGACATCGTCGCCA
AGGAAACGTCCCGCCTTCTCACCCAATTGCAGCCGAAGGTCGACACGATCCACGAGGACCTGACGGCGGCGGGCGAGGAT
CTCGGCCGCATGCTGCTGCAGCGCATCAACAATGCCGACACCGAAGGCCTGCATCTTCTGCTGCCGCCGCAGATCAATTT
CCCGGTCGGTTAA

Upstream 100 bases:

>100_bases
TGGCTAACAGATCGTTAAAATTTAAAACGTTTTCATTCCTCGATTGCGCGTCCAAGTCATCGTGTTATTGTATCGCCAAT
TCCAGCATGGAAAGCCGAGA

Downstream 100 bases:

>100_bases
GCCCAGGCTATTCCCAACAGGCGTTATTTGCCCTAGAAGCACGCCGTAATCCGGTCGCAGCCCACCCGGTCAAAACAAGG
GATCCAAAATATGAGAACCA

Product: LacI family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 350; Mature: 349

Protein sequence:

>350_residues
MTEPSRPRSGENLEITHKRGKPTLRTIATIAGLAVTTVSRALSDAPQISLETRQRVHRIAREIGYLPDRAAQRLKTGRTN
VIAILLDSHEEVVGFSTSIMYGIAKALKETSYHLVVAPNFLSTTDVEAAEYIVRNHLADGLIFTRTEPLDARVRLLLETG
FPFICHGRTEFSTPHPYVDYDNFTFAYEATRRLIAKDRKKVAVVLPPKRLTFCQHILHGFMTAVREAGIAYEIPETVDLD
TPADALRDFISSRAAAPEAPDGFICPGEVSALAVISGMSDAGRTLAVDYDIVAKETSRLLTQLQPKVDTIHEDLTAAGED
LGRMLLQRINNADTEGLHLLLPPQINFPVG

Sequences:

>Translated_350_residues
MTEPSRPRSGENLEITHKRGKPTLRTIATIAGLAVTTVSRALSDAPQISLETRQRVHRIAREIGYLPDRAAQRLKTGRTN
VIAILLDSHEEVVGFSTSIMYGIAKALKETSYHLVVAPNFLSTTDVEAAEYIVRNHLADGLIFTRTEPLDARVRLLLETG
FPFICHGRTEFSTPHPYVDYDNFTFAYEATRRLIAKDRKKVAVVLPPKRLTFCQHILHGFMTAVREAGIAYEIPETVDLD
TPADALRDFISSRAAAPEAPDGFICPGEVSALAVISGMSDAGRTLAVDYDIVAKETSRLLTQLQPKVDTIHEDLTAAGED
LGRMLLQRINNADTEGLHLLLPPQINFPVG
>Mature_349_residues
TEPSRPRSGENLEITHKRGKPTLRTIATIAGLAVTTVSRALSDAPQISLETRQRVHRIAREIGYLPDRAAQRLKTGRTNV
IAILLDSHEEVVGFSTSIMYGIAKALKETSYHLVVAPNFLSTTDVEAAEYIVRNHLADGLIFTRTEPLDARVRLLLETGF
PFICHGRTEFSTPHPYVDYDNFTFAYEATRRLIAKDRKKVAVVLPPKRLTFCQHILHGFMTAVREAGIAYEIPETVDLDT
PADALRDFISSRAAAPEAPDGFICPGEVSALAVISGMSDAGRTLAVDYDIVAKETSRLLTQLQPKVDTIHEDLTAAGEDL
GRMLLQRINNADTEGLHLLLPPQINFPVG

Specific function: Binds to the 14-bp operator sequence 5'-TGGGAGCGCTCCCA- 3' in the upstream regions of cellulase genes; these operator sequences are modulated by cellobiose [H]

COG id: COG1609

COG function: function code K; Transcriptional regulators

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lacI-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1790369, Length=312, Percent_Identity=24.0384615384615, Blast_Score=87, Evalue=2e-18,
Organism=Escherichia coli, GI1787948, Length=327, Percent_Identity=24.1590214067278, Blast_Score=86, Evalue=3e-18,
Organism=Escherichia coli, GI1787580, Length=246, Percent_Identity=24.7967479674797, Blast_Score=71, Evalue=1e-13,
Organism=Escherichia coli, GI1790194, Length=326, Percent_Identity=21.4723926380368, Blast_Score=68, Evalue=7e-13,
Organism=Escherichia coli, GI1789202, Length=217, Percent_Identity=24.4239631336406, Blast_Score=63, Evalue=3e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000843
- InterPro:   IPR010982
- InterPro:   IPR001761 [H]

Pfam domain/function: PF00356 LacI; PF00532 Peripla_BP_1 [H]

EC number: NA

Molecular weight: Translated: 38590; Mature: 38458

Theoretical pI: Translated: 6.59; Mature: 6.59

Prosite motif: PS50932 HTH_LACI_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTEPSRPRSGENLEITHKRGKPTLRTIATIAGLAVTTVSRALSDAPQISLETRQRVHRIA
CCCCCCCCCCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHH
REIGYLPDRAAQRLKTGRTNVIAILLDSHEEVVGFSTSIMYGIAKALKETSYHLVVAPNF
HHHCCCCHHHHHHHHCCCCEEEEEEECCCCHHHHHHHHHHHHHHHHHHHCCCEEEECCCC
LSTTDVEAAEYIVRNHLADGLIFTRTEPLDARVRLLLETGFPFICHGRTEFSTPHPYVDY
CCCCCHHHHHHHHHHHHHCCEEEECCCCHHHHHHHHHHCCCCEEECCCCCCCCCCCCCCC
DNFTFAYEATRRLIAKDRKKVAVVLPPKRLTFCQHILHGFMTAVREAGIAYEIPETVDLD
CCEEEHHHHHHHHHHHCCCCEEEEECCHHHHHHHHHHHHHHHHHHHCCCEEECCCCCCCC
TPADALRDFISSRAAAPEAPDGFICPGEVSALAVISGMSDAGRTLAVDYDIVAKETSRLL
CCHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHCCCCCCCEEEEEHHHHHHHHHHHH
TQLQPKVDTIHEDLTAAGEDLGRMLLQRINNADTEGLHLLLPPQINFPVG
HHHCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEECCCCCCCCC
>Mature Secondary Structure 
TEPSRPRSGENLEITHKRGKPTLRTIATIAGLAVTTVSRALSDAPQISLETRQRVHRIA
CCCCCCCCCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHH
REIGYLPDRAAQRLKTGRTNVIAILLDSHEEVVGFSTSIMYGIAKALKETSYHLVVAPNF
HHHCCCCHHHHHHHHCCCCEEEEEEECCCCHHHHHHHHHHHHHHHHHHHCCCEEEECCCC
LSTTDVEAAEYIVRNHLADGLIFTRTEPLDARVRLLLETGFPFICHGRTEFSTPHPYVDY
CCCCCHHHHHHHHHHHHHCCEEEECCCCHHHHHHHHHHCCCCEEECCCCCCCCCCCCCCC
DNFTFAYEATRRLIAKDRKKVAVVLPPKRLTFCQHILHGFMTAVREAGIAYEIPETVDLD
CCEEEHHHHHHHHHHHCCCCEEEEECCHHHHHHHHHHHHHHHHHHHCCCEEECCCCCCCC
TPADALRDFISSRAAAPEAPDGFICPGEVSALAVISGMSDAGRTLAVDYDIVAKETSRLL
CCHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHCCCCCCCEEEEEHHHHHHHHHHHH
TQLQPKVDTIHEDLTAAGEDLGRMLLQRINNADTEGLHLLLPPQINFPVG
HHHCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEECCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10224066 [H]