Click here to switch to the map view.

The map label for this gene is yybE [H]

Identifier: 209550998

GI number: 209550998

Start: 3539098

End: 3540006

Strand: Direct

Name: yybE [H]

Synonym: Rleg2_3422

Alternate gene names: 209550998

Gene position: 3539098-3540006 (Clockwise)

Preceding gene: 209550996

Following gene: 209550999

Centisome position: 77.99

GC content: 66.67

Gene sequence:

>909_bases
ATGGCCTTCACGCTTCGCCAGGTTCAATATTTTGTCGCCGTCGCCGAACAGGGCTCGGTAACGCGCGCCGCACAGAACCT
GTCGATCTCGCAATCCTCGGTGACGGAGGCGCTAAAAGAGCTCGAAACCGACCTCGGCGTTGCGCTCTTCGAGCGCCATC
CGCGCGGCCTGGCGATCACCCATAACGGCCACCAGTTCCTGCGTCACGCAACGAAGATCCTCGCCTCCGTCTCCGATGCG
CGCACCAGCTTCGCCGGCCAGCAAAGCGCGCTTTCCGGCACGCTGAACATCGGCGTCACCTCGCTTGTCGCCGGCTACGT
GCTCTCCGACCTCCTGGCGCGATACCGGCGCGCCTGCCCCGGCATCGAGGTCAGCGCCATCGAGGACAATGGCGGGTACC
TCGAACATCTCCTGGTCGGCGGCGAACTCGACGTCGCCGTCATGGTGATCTCGAACCTGCGCGACCGCATGGCGCTGCAG
GCCGAGATCCTCGAAACCTCGCCCTATCGGCTCTGGCTGCCGATGGGCCATCCGCTGGTATCGGCCGACATCATCTCGGT
CGCCGATATCGCCCGCGAGCCGCTGATCATGCTGACCGTCGACGAAATCGAGGAGAATACCGGCAAGCTGCTCTCGGCGC
TTGGCGCCCGCCCGCATGTCGCCTTCCGCACCCGCTCGGTGGAGGCGGTGCGCAGCCTGGTGGCGACAGGCGCCGGCGTG
GCGCTGCTTCCCGATCTCGTCTATCGCCCTTGGTCGCTCGAAGGCGACCGGATCGAAAGCCGCGACGTCTCCGGATCGCT
GCCCGTCGTCCAGGTCGGCATGGTCTGGCGCAAGGGCTCCAGCCTGCCGCAGGCCGCACGCGATTTCGTCGGCATCGCCG
AAAGTCTGCGGTCCGGCCGCATCCGCTGA

Upstream 100 bases:

>100_bases
AGTGAGGGTGCGAAGCCTGCGCCATTTTGAGAAAAGACCAAAAAAGGTCCGCTTTTTTCGGCCGCTTGCCACGGCCTGTT
TCGCCATGCTCTAAACGCTC

Downstream 100 bases:

>100_bases
TATCGGAATTTCCGATAACGCCTTTCTGATAAATGAATTTGCGAAAGCGGCCTTTTCGCGTCACCTTCTTCCGAGGGAAC
AAACCGCCACGGAAAGTGGC

Product: LysR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 302; Mature: 301

Protein sequence:

>302_residues
MAFTLRQVQYFVAVAEQGSVTRAAQNLSISQSSVTEALKELETDLGVALFERHPRGLAITHNGHQFLRHATKILASVSDA
RTSFAGQQSALSGTLNIGVTSLVAGYVLSDLLARYRRACPGIEVSAIEDNGGYLEHLLVGGELDVAVMVISNLRDRMALQ
AEILETSPYRLWLPMGHPLVSADIISVADIAREPLIMLTVDEIEENTGKLLSALGARPHVAFRTRSVEAVRSLVATGAGV
ALLPDLVYRPWSLEGDRIESRDVSGSLPVVQVGMVWRKGSSLPQAARDFVGIAESLRSGRIR

Sequences:

>Translated_302_residues
MAFTLRQVQYFVAVAEQGSVTRAAQNLSISQSSVTEALKELETDLGVALFERHPRGLAITHNGHQFLRHATKILASVSDA
RTSFAGQQSALSGTLNIGVTSLVAGYVLSDLLARYRRACPGIEVSAIEDNGGYLEHLLVGGELDVAVMVISNLRDRMALQ
AEILETSPYRLWLPMGHPLVSADIISVADIAREPLIMLTVDEIEENTGKLLSALGARPHVAFRTRSVEAVRSLVATGAGV
ALLPDLVYRPWSLEGDRIESRDVSGSLPVVQVGMVWRKGSSLPQAARDFVGIAESLRSGRIR
>Mature_301_residues
AFTLRQVQYFVAVAEQGSVTRAAQNLSISQSSVTEALKELETDLGVALFERHPRGLAITHNGHQFLRHATKILASVSDAR
TSFAGQQSALSGTLNIGVTSLVAGYVLSDLLARYRRACPGIEVSAIEDNGGYLEHLLVGGELDVAVMVISNLRDRMALQA
EILETSPYRLWLPMGHPLVSADIISVADIAREPLIMLTVDEIEENTGKLLSALGARPHVAFRTRSVEAVRSLVATGAGVA
LLPDLVYRPWSLEGDRIESRDVSGSLPVVQVGMVWRKGSSLPQAARDFVGIAESLRSGRIR

Specific function: Hydrogen Peroxide Sensor. Activates The Expression Of A Regulon Of Hydrogen Peroxide-Inducible Genes Such As Katg, Gor, Ahpc, Ahpf, Oxys (A Regulatory RNA), Dps, Fur And Grxa. Oxyr Expression Is Negatively Autoregulated By Binding To A 43 Bp Region Upstre

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1790399, Length=304, Percent_Identity=28.6184210526316, Blast_Score=111, Evalue=6e-26,
Organism=Escherichia coli, GI1787879, Length=294, Percent_Identity=27.5510204081633, Blast_Score=101, Evalue=8e-23,
Organism=Escherichia coli, GI157672245, Length=289, Percent_Identity=26.643598615917, Blast_Score=96, Evalue=2e-21,
Organism=Escherichia coli, GI1788887, Length=300, Percent_Identity=28.3333333333333, Blast_Score=94, Evalue=8e-21,
Organism=Escherichia coli, GI1787601, Length=248, Percent_Identity=26.6129032258064, Blast_Score=88, Evalue=5e-19,
Organism=Escherichia coli, GI1787806, Length=279, Percent_Identity=27.5985663082437, Blast_Score=87, Evalue=1e-18,
Organism=Escherichia coli, GI87081904, Length=180, Percent_Identity=27.7777777777778, Blast_Score=79, Evalue=4e-16,
Organism=Escherichia coli, GI2367136, Length=264, Percent_Identity=25.7575757575758, Blast_Score=74, Evalue=2e-14,
Organism=Escherichia coli, GI1786401, Length=273, Percent_Identity=26.3736263736264, Blast_Score=70, Evalue=2e-13,
Organism=Escherichia coli, GI1788297, Length=258, Percent_Identity=27.5193798449612, Blast_Score=70, Evalue=2e-13,
Organism=Escherichia coli, GI1788748, Length=295, Percent_Identity=24.7457627118644, Blast_Score=69, Evalue=3e-13,
Organism=Escherichia coli, GI1789639, Length=145, Percent_Identity=31.0344827586207, Blast_Score=69, Evalue=3e-13,
Organism=Escherichia coli, GI1788481, Length=124, Percent_Identity=33.0645161290323, Blast_Score=69, Evalue=3e-13,
Organism=Escherichia coli, GI87082132, Length=144, Percent_Identity=30.5555555555556, Blast_Score=68, Evalue=8e-13,
Organism=Escherichia coli, GI1788296, Length=241, Percent_Identity=25.3112033195021, Blast_Score=68, Evalue=8e-13,
Organism=Escherichia coli, GI1787530, Length=320, Percent_Identity=23.4375, Blast_Score=68, Evalue=9e-13,
Organism=Escherichia coli, GI1790208, Length=247, Percent_Identity=26.7206477732794, Blast_Score=66, Evalue=2e-12,
Organism=Escherichia coli, GI1788626, Length=237, Percent_Identity=28.6919831223629, Blast_Score=66, Evalue=3e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 32619; Mature: 32488

Theoretical pI: Translated: 6.64; Mature: 6.64

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAFTLRQVQYFVAVAEQGSVTRAAQNLSISQSSVTEALKELETDLGVALFERHPRGLAIT
CCCHHHHHHHHHHHHCCCCHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCEEEE
HNGHQFLRHATKILASVSDARTSFAGQQSALSGTLNIGVTSLVAGYVLSDLLARYRRACP
ECHHHHHHHHHHHHHHHHHHHHHHCCCHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHCC
GIEVSAIEDNGGYLEHLLVGGELDVAVMVISNLRDRMALQAEILETSPYRLWLPMGHPLV
CCEEEEEECCCCEEEHEEECCCHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCH
SADIISVADIAREPLIMLTVDEIEENTGKLLSALGARPHVAFRTRSVEAVRSLVATGAGV
HHHHHHHHHHHHCCEEEEEHHHHHHHHHHHHHHHCCCCCEEEEHHHHHHHHHHHHCCCCH
ALLPDLVYRPWSLEGDRIESRDVSGSLPVVQVGMVWRKGSSLPQAARDFVGIAESLRSGR
HHHHHHHCCCCCCCCCCCCCCCCCCCCCEEEEEEEEECCCCCHHHHHHHHHHHHHHHCCC
IR
CC
>Mature Secondary Structure 
AFTLRQVQYFVAVAEQGSVTRAAQNLSISQSSVTEALKELETDLGVALFERHPRGLAIT
CCHHHHHHHHHHHHCCCCHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCEEEE
HNGHQFLRHATKILASVSDARTSFAGQQSALSGTLNIGVTSLVAGYVLSDLLARYRRACP
ECHHHHHHHHHHHHHHHHHHHHHHCCCHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHCC
GIEVSAIEDNGGYLEHLLVGGELDVAVMVISNLRDRMALQAEILETSPYRLWLPMGHPLV
CCEEEEEECCCCEEEHEEECCCHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCH
SADIISVADIAREPLIMLTVDEIEENTGKLLSALGARPHVAFRTRSVEAVRSLVATGAGV
HHHHHHHHHHHHCCEEEEEHHHHHHHHHHHHHHHCCCCCEEEEHHHHHHHHHHHHCCCCH
ALLPDLVYRPWSLEGDRIESRDVSGSLPVVQVGMVWRKGSSLPQAARDFVGIAESLRSGR
HHHHHHHCCCCCCCCCCCCCCCCCCCCCEEEEEEEEECCCCCHHHHHHHHHHHHHHHCCC
IR
CC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7584024; 9384377 [H]