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The map label for this gene is abg [H]

Identifier: 209550979

GI number: 209550979

Start: 3515223

End: 3516596

Strand: Reverse

Name: abg [H]

Synonym: Rleg2_3403

Alternate gene names: 209550979

Gene position: 3516596-3515223 (Counterclockwise)

Preceding gene: 209550981

Following gene: 209550978

Centisome position: 77.49

GC content: 61.21

Gene sequence:

>1374_bases
ATGATCGATGCGAAGACGCTTGCAAGCCGCCTTCCCGGCGATTTCACCTTCGGCGTCGCCACCGCCGCCTTCCAGATCGA
GGGTGCTGGTAAGGCCGACGGCCGCAAGCCATCGATCTGGGATGCTTTCTGCAATATGCCCGGCCGTGTCTATAATCGCG
ACAATGGCGACGTCGCCTGCGACCACTATAACCGGCTAGAGCAGGATCTCGATCTCATCAAGGATATGGGTGTCGAAGCC
TACCGCTTCTCGATCGCCTGGCCGCGCATCATCCCCGACGGCACCGGTGCGGTGAACGAGGCCGGGCTCGATTTCTACGA
TCGGCTGGTCGACGGCTGCAAGGCGCGCGGGATCAAGACCTTTGCGACGCTCTATCACTGGGACCTGCCACTAATGCTTG
CCGGCGACGGCGGCTGGACGGCGCGCTCGACCGCCTATGCCTTTCAGCGCTACGCCAAGACGGTGATGAACCGGCTTGGC
GATCGTCTCGATGCCGTCGCGACCTTCAACGAGCCCTGGTGCATCGTCTGGCTGAGCCACCTCTACGGCATCCACGCGCC
GGGCGAGCGCAATATTCAGGCCGCCCTTCACGCCATGCACTACATGAACCTCGCCCACGGTCTCGGCGTCGAGGCGATCC
GTGCGGAAGCCCCTGCGGTGCCCGTCGGGCTCGTGCTCAACGCTGCCTCGATCATCCCCGGTTCCGAGGGCCCGGCCGAT
CTTGCCGCCACTGAGCGCGCGCATCAGTTTCACAACGGCGCTTTCTTCGATCCCGTCTTCAAGGGCGAATACCCCAAGGA
ATTCGTTGAGGCGCTCGGCGACCGCATGCCTGTCATCGAGGACGGCGACATGACGCTGATCAGCCAGAAACTCGACTGGT
GGGGTCTGAATTATTACACGCCCGAGCGCGTCACTGACGATGCCGAACGCAACGGCGATTTCCCCTGGACGGTGAAAGCG
CCGCCGGCAAGCGACGTCAAAACCGATATCGGCTGGGAAATCTATGCGCCGGGATTGAAGCTGCTGGTCGAAAACCTTTA
CCGCCGCTACGAACTGCCGGAATGCTACATCACTGAGAACGGCGCTTGCGACAACACCGGTGTCGTCGACGGCGAAGTCG
ACGATACGATGCGTCTCGATTATCTCGGCGACCATCTCGATGTCGTGGCCGGCCTTATCAAGGACGGTTATCCCATGCGC
GGCTATTTCGCCTGGAGCCTGATGGACAATTTCGAATGGGCAGAAGGCTACCGCATGCGCTTCGGCCTCGTCCATGTCGA
TTATCAGACCCAGTTGCGTACGGTGAAGAAGAGCGGCAAGTGGTATCGCGAACTCGCAGCACAATTCCCGAAGGGCAATC
ACAAGGCGGGTTAG

Upstream 100 bases:

>100_bases
CGTTGCAGTTTTTCCGCTCCCGGGCCTGTACTTTGCTTTCTGGCTTGGCTAATTCCGAGCCCGGACGATCCATTCACCCG
CTGAGGATTGGGATTTACAG

Downstream 100 bases:

>100_bases
GTGAAACGGCTGACGTTGCTTCGCTCATTTTCACATCAGCAGGCAAGAAATAGCTCCTCGCAAATCTTCAACAGGTGGTT
GCTTAAACGTTTTTGAACCC

Product: beta-galactosidase

Products: NA

Alternate protein names: Amygdalase; Beta-D-glucoside glucohydrolase; Cellobiase; Gentiobiase [H]

Number of amino acids: Translated: 457; Mature: 457

Protein sequence:

>457_residues
MIDAKTLASRLPGDFTFGVATAAFQIEGAGKADGRKPSIWDAFCNMPGRVYNRDNGDVACDHYNRLEQDLDLIKDMGVEA
YRFSIAWPRIIPDGTGAVNEAGLDFYDRLVDGCKARGIKTFATLYHWDLPLMLAGDGGWTARSTAYAFQRYAKTVMNRLG
DRLDAVATFNEPWCIVWLSHLYGIHAPGERNIQAALHAMHYMNLAHGLGVEAIRAEAPAVPVGLVLNAASIIPGSEGPAD
LAATERAHQFHNGAFFDPVFKGEYPKEFVEALGDRMPVIEDGDMTLISQKLDWWGLNYYTPERVTDDAERNGDFPWTVKA
PPASDVKTDIGWEIYAPGLKLLVENLYRRYELPECYITENGACDNTGVVDGEVDDTMRLDYLGDHLDVVAGLIKDGYPMR
GYFAWSLMDNFEWAEGYRMRFGLVHVDYQTQLRTVKKSGKWYRELAAQFPKGNHKAG

Sequences:

>Translated_457_residues
MIDAKTLASRLPGDFTFGVATAAFQIEGAGKADGRKPSIWDAFCNMPGRVYNRDNGDVACDHYNRLEQDLDLIKDMGVEA
YRFSIAWPRIIPDGTGAVNEAGLDFYDRLVDGCKARGIKTFATLYHWDLPLMLAGDGGWTARSTAYAFQRYAKTVMNRLG
DRLDAVATFNEPWCIVWLSHLYGIHAPGERNIQAALHAMHYMNLAHGLGVEAIRAEAPAVPVGLVLNAASIIPGSEGPAD
LAATERAHQFHNGAFFDPVFKGEYPKEFVEALGDRMPVIEDGDMTLISQKLDWWGLNYYTPERVTDDAERNGDFPWTVKA
PPASDVKTDIGWEIYAPGLKLLVENLYRRYELPECYITENGACDNTGVVDGEVDDTMRLDYLGDHLDVVAGLIKDGYPMR
GYFAWSLMDNFEWAEGYRMRFGLVHVDYQTQLRTVKKSGKWYRELAAQFPKGNHKAG
>Mature_457_residues
MIDAKTLASRLPGDFTFGVATAAFQIEGAGKADGRKPSIWDAFCNMPGRVYNRDNGDVACDHYNRLEQDLDLIKDMGVEA
YRFSIAWPRIIPDGTGAVNEAGLDFYDRLVDGCKARGIKTFATLYHWDLPLMLAGDGGWTARSTAYAFQRYAKTVMNRLG
DRLDAVATFNEPWCIVWLSHLYGIHAPGERNIQAALHAMHYMNLAHGLGVEAIRAEAPAVPVGLVLNAASIIPGSEGPAD
LAATERAHQFHNGAFFDPVFKGEYPKEFVEALGDRMPVIEDGDMTLISQKLDWWGLNYYTPERVTDDAERNGDFPWTVKA
PPASDVKTDIGWEIYAPGLKLLVENLYRRYELPECYITENGACDNTGVVDGEVDDTMRLDYLGDHLDVVAGLIKDGYPMR
GYFAWSLMDNFEWAEGYRMRFGLVHVDYQTQLRTVKKSGKWYRELAAQFPKGNHKAG

Specific function: Can Hydrolyze Salicin And Arbutin. [C]

COG id: COG2723

COG function: function code G; Beta-glucosidase/6-phospho-beta-glucosidase/beta-galactosidase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glycosyl hydrolase 1 family [H]

Homologues:

Organism=Homo sapiens, GI32481206, Length=477, Percent_Identity=34.5911949685535, Blast_Score=241, Evalue=9e-64,
Organism=Homo sapiens, GI110681710, Length=476, Percent_Identity=32.1428571428571, Blast_Score=226, Evalue=5e-59,
Organism=Homo sapiens, GI13273313, Length=447, Percent_Identity=31.9910514541387, Blast_Score=223, Evalue=3e-58,
Organism=Homo sapiens, GI28376633, Length=454, Percent_Identity=29.9559471365639, Blast_Score=185, Evalue=1e-46,
Organism=Homo sapiens, GI24497614, Length=464, Percent_Identity=29.5258620689655, Blast_Score=164, Evalue=1e-40,
Organism=Homo sapiens, GI190360571, Length=97, Percent_Identity=44.3298969072165, Blast_Score=94, Evalue=4e-19,
Organism=Escherichia coli, GI2367270, Length=455, Percent_Identity=32.0879120879121, Blast_Score=187, Evalue=1e-48,
Organism=Escherichia coli, GI2367174, Length=472, Percent_Identity=30.5084745762712, Blast_Score=182, Evalue=4e-47,
Organism=Escherichia coli, GI1789070, Length=472, Percent_Identity=29.0254237288136, Blast_Score=166, Evalue=3e-42,
Organism=Caenorhabditis elegans, GI17552856, Length=473, Percent_Identity=30.6553911205074, Blast_Score=222, Evalue=3e-58,
Organism=Caenorhabditis elegans, GI17539390, Length=479, Percent_Identity=30.8977035490605, Blast_Score=219, Evalue=3e-57,
Organism=Drosophila melanogaster, GI21356577, Length=478, Percent_Identity=33.8912133891213, Blast_Score=239, Evalue=3e-63,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001360
- InterPro:   IPR018120
- InterPro:   IPR017736
- InterPro:   IPR017853
- InterPro:   IPR013781 [H]

Pfam domain/function: PF00232 Glyco_hydro_1 [H]

EC number: =3.2.1.21 [H]

Molecular weight: Translated: 51089; Mature: 51089

Theoretical pI: Translated: 4.95; Mature: 4.95

Prosite motif: PS00572 GLYCOSYL_HYDROL_F1_1 ; PS00653 GLYCOSYL_HYDROL_F1_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIDAKTLASRLPGDFTFGVATAAFQIEGAGKADGRKPSIWDAFCNMPGRVYNRDNGDVAC
CCCHHHHHHHCCCCEEEEEEEEEEEEECCCCCCCCCCCHHHHHHCCCCCEEECCCCCEEC
DHYNRLEQDLDLIKDMGVEAYRFSIAWPRIIPDGTGAVNEAGLDFYDRLVDGCKARGIKT
HHHHHHHHHHHHHHHCCCCEEEEEEECCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCHHH
FATLYHWDLPLMLAGDGGWTARSTAYAFQRYAKTVMNRLGDRLDAVATFNEPWCIVWLSH
HHHHHCCCCCEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHEECCCCCHHHHHHH
LYGIHAPGERNIQAALHAMHYMNLAHGLGVEAIRAEAPAVPVGLVLNAASIIPGSEGPAD
HHCCCCCCCCHHHHHHHHHHHHHHHHCCCHHHHHCCCCCCCHHHHHHHHHHCCCCCCCHH
LAATERAHQFHNGAFFDPVFKGEYPKEFVEALGDRMPVIEDGDMTLISQKLDWWGLNYYT
HHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHCCCCCEEECCCEEEEECCCCCCCCCCCC
PERVTDDAERNGDFPWTVKAPPASDVKTDIGWEIYAPGLKLLVENLYRRYELPECYITEN
CCCCCCCHHHCCCCCEEEECCCCCCCCCCCCCEEECCHHHHHHHHHHHHCCCCEEEEECC
GACDNTGVVDGEVDDTMRLDYLGDHLDVVAGLIKDGYPMRGYFAWSLMDNFEWAEGYRMR
CCCCCCCCCCCCCCCCEEHHHHCHHHHHHHHHHHCCCCCCCEEEEEHHCCCCCCCCCEEE
FGLVHVDYQTQLRTVKKSGKWYRELAAQFPKGNHKAG
EEEEEECHHHHHHHHHHCCHHHHHHHHHCCCCCCCCC
>Mature Secondary Structure
MIDAKTLASRLPGDFTFGVATAAFQIEGAGKADGRKPSIWDAFCNMPGRVYNRDNGDVAC
CCCHHHHHHHCCCCEEEEEEEEEEEEECCCCCCCCCCCHHHHHHCCCCCEEECCCCCEEC
DHYNRLEQDLDLIKDMGVEAYRFSIAWPRIIPDGTGAVNEAGLDFYDRLVDGCKARGIKT
HHHHHHHHHHHHHHHCCCCEEEEEEECCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCHHH
FATLYHWDLPLMLAGDGGWTARSTAYAFQRYAKTVMNRLGDRLDAVATFNEPWCIVWLSH
HHHHHCCCCCEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHEECCCCCHHHHHHH
LYGIHAPGERNIQAALHAMHYMNLAHGLGVEAIRAEAPAVPVGLVLNAASIIPGSEGPAD
HHCCCCCCCCHHHHHHHHHHHHHHHHCCCHHHHHCCCCCCCHHHHHHHHHHCCCCCCCHH
LAATERAHQFHNGAFFDPVFKGEYPKEFVEALGDRMPVIEDGDMTLISQKLDWWGLNYYT
HHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHCCCCCEEECCCEEEEECCCCCCCCCCCC
PERVTDDAERNGDFPWTVKAPPASDVKTDIGWEIYAPGLKLLVENLYRRYELPECYITEN
CCCCCCCHHHCCCCCEEEECCCCCCCCCCCCCEEECCHHHHHHHHHHHHCCCCEEEEECC
GACDNTGVVDGEVDDTMRLDYLGDHLDVVAGLIKDGYPMRGYFAWSLMDNFEWAEGYRMR
CCCCCCCCCCCCCCCCEEHHHHCHHHHHHHHHHHCCCCCCCEEEEEHHCCCCCCCCCEEE
FGLVHVDYQTQLRTVKKSGKWYRELAAQFPKGNHKAG
EEEEEECHHHHHHHHHHCCHHHHHHHHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 2826395 [H]