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The map label for this gene is pntAB [H]

Identifier: 209550943

GI number: 209550943

Start: 3478654

End: 3479052

Strand: Reverse

Name: pntAB [H]

Synonym: Rleg2_3367

Alternate gene names: 209550943

Gene position: 3479052-3478654 (Counterclockwise)

Preceding gene: 209550944

Following gene: 209550942

Centisome position: 76.67

GC content: 63.16

Gene sequence:

>399_bases
ATGGCCAGTGAAGCAATGGACAAAGCGCTGGAGCAGCTCGACCAGGCGGTCACCGCCGTCGTCACGGCAGCGGCCCATGC
GCCGGAAGCGGCCAGTGCTGCGACAGGCGGGGCGATCGATCCCTTCGTCTTCCAGCTGGCGATCTTCGTCTTGTCGATCT
TCGTCGGTTATTACGTCGTGTGGTCGGTGACGCCGGCGCTGCATACGCCGCTGATGGCCGTCACCAATGCGATCTCCTCC
GTTATCGTCGTCGGCGCGCTTCTGGCAGTCGGCATCTCGACAAGCGGGCTTGCGACCGGCTTCGGCTTCGTCGCCCTCGT
GCTCGTCTCGGTGAACATTTTCGGCGGCTTCCTCGTGACGCAGCGAATGCTCTCGATGTACCGCAAGAAAGACCGGTGA

Upstream 100 bases:

>100_bases
TCGTCAACCTCGACGACGAACTCGTCAAGGCGACGATGCTGACCTATGCCGGCGACGTGGTGCATCCCGCCTTCGGCGGC
GCGAAGAAGGGAGATCTCTG

Downstream 100 bases:

>100_bases
GGAACCGATGACCAATATCGCAGCCTTCCTCTACCTCGTCTCCGGCGTTCTCTTCATCCTGGCGCTGCGGGGTCTCTCGC
ATCCTGCCACCAGCCGCAAG

Product: NAD(P)(+) transhydrogenase protein subunit alpha

Products: NA

Alternate protein names: Nicotinamide nucleotide transhydrogenase subunit alpha 2; Proton-translocating transhydrogenase component 2; Pyridine nucleotide transhydrogenase subunit alpha 2; dII [H]

Number of amino acids: Translated: 132; Mature: 131

Protein sequence:

>132_residues
MASEAMDKALEQLDQAVTAVVTAAAHAPEAASAATGGAIDPFVFQLAIFVLSIFVGYYVVWSVTPALHTPLMAVTNAISS
VIVVGALLAVGISTSGLATGFGFVALVLVSVNIFGGFLVTQRMLSMYRKKDR

Sequences:

>Translated_132_residues
MASEAMDKALEQLDQAVTAVVTAAAHAPEAASAATGGAIDPFVFQLAIFVLSIFVGYYVVWSVTPALHTPLMAVTNAISS
VIVVGALLAVGISTSGLATGFGFVALVLVSVNIFGGFLVTQRMLSMYRKKDR
>Mature_131_residues
ASEAMDKALEQLDQAVTAVVTAAAHAPEAASAATGGAIDPFVFQLAIFVLSIFVGYYVVWSVTPALHTPLMAVTNAISSV
IVVGALLAVGISTSGLATGFGFVALVLVSVNIFGGFLVTQRMLSMYRKKDR

Specific function: The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane [H]

COG id: COG3288

COG function: function code C; NAD/NADP transhydrogenase alpha subunit

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Homo sapiens, GI122939155, Length=83, Percent_Identity=53.0120481927711, Blast_Score=85, Evalue=2e-17,
Organism=Homo sapiens, GI122939153, Length=83, Percent_Identity=53.0120481927711, Blast_Score=85, Evalue=2e-17,
Organism=Escherichia coli, GI1787887, Length=89, Percent_Identity=57.3033707865169, Blast_Score=107, Evalue=3e-25,
Organism=Caenorhabditis elegans, GI17550456, Length=85, Percent_Identity=51.7647058823529, Blast_Score=87, Evalue=2e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

NA

Pfam domain/function: NA

EC number: =1.6.1.2 [H]

Molecular weight: Translated: 13693; Mature: 13562

Theoretical pI: Translated: 6.51; Mature: 6.51

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.8 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MASEAMDKALEQLDQAVTAVVTAAAHAPEAASAATGGAIDPFVFQLAIFVLSIFVGYYVV
CCHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHH
WSVTPALHTPLMAVTNAISSVIVVGALLAVGISTSGLATGFGFVALVLVSVNIFGGFLVT
HHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
QRMLSMYRKKDR
HHHHHHHHHCCC
>Mature Secondary Structure 
ASEAMDKALEQLDQAVTAVVTAAAHAPEAASAATGGAIDPFVFQLAIFVLSIFVGYYVV
CHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHH
WSVTPALHTPLMAVTNAISSVIVVGALLAVGISTSGLATGFGFVALVLVSVNIFGGFLVT
HHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
QRMLSMYRKKDR
HHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 8075801 [H]