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The map label for this gene is gcvT [H]

Identifier: 209550886

GI number: 209550886

Start: 3399610

End: 3402060

Strand: Direct

Name: gcvT [H]

Synonym: Rleg2_3310

Alternate gene names: 209550886

Gene position: 3399610-3402060 (Clockwise)

Preceding gene: 209550884

Following gene: 209550887

Centisome position: 74.92

GC content: 61.2

Gene sequence:

>2451_bases
ATGTCGAATTTGCCATCTCAGGCGCGCGTTGTGATCATCGGCGGAGGAGCTGTCGGCGTATCCGCCCTCTATCATCTGGC
CATGGCGGGCTGGACCGACGCGGTGCTTCTGGAAAAAAACGAACTGACTGCCGGATCGACGTGGCATGCGGCCGGCAATG
TGCCGACGTTTTCTTCTTCCTGGTCGATCATGAACATGCAGCGCTATTCCGCCTCGCTCTATCGCGAGCTGGGCGCTCAG
GTCGACTATCCGATGAACTACCACGTGACCGGCTCGATCCGGCTCGGCCACTCGAACGAGCGGCTGCAGGAATTCAAGCG
TGTGGTCGGCATGGGACGCTACCAGGGCATGGACCTCGACATCCTGTCGCCCGATCAGATCAAATCGAAATATCCCTTTG
TCGAGACCCATGACCTCATCGGCGCGCTCCACGATCCGCATGACGGCGACATCGATCCGGCGCAGCTGACCCAGGCCTTG
GCAAAGGGCGCGCGCGACCTGGGGGCGCGGATCTTCCGCTTCTGTGCCGCAATCGGTGCGCGCAGGGAAAACAACGAATG
GATCGTTTCCACCCCGGACGGTGATATCCGCTGCGAATATGTCGTCAATGCCGCCGGCTATTACGCCCGCGAAGTCGGCA
AATGGTTCGGCCGCGAGGTGCCGATGATGGTGATGAGCCATCAGTACATGCTGTTCGAAGAAATTCCTGAGCTTGCCGCA
TGGTCGAAAGAGGCAGGCCACAAGCTGCCGCTGCTGCGAGACGTCGATAGTTCCTACTATCTGCGGCAGGAAAAGACCGG
AATGAACCTCGGTCCCTATGAGCGCAATTGCAAGGCGCATTGGCTGACGCCCGAGGATCCGATGCCGGAGGATTTCTCCT
TCCAGCTTTTCCCCGACGATCTCGAGCGGCTGGAATGGTATCTCAATGACGCTGTCGAGCGCGTGCCGATCCTCGGCACT
GCCGGTCTGTCGCGCATGATCAACGGACCTATCCCCTATACACCGGACGGCAATCCGCTGATCGGGCCGATGCCGGGCGT
GCCGAATGCGTTTGAGGCCTGCGTCTTCACCTTCGGTATCTGCCAGGCGGGCGGTGCCGGCAAGGTGCTGGCCGAATGGC
TGACCGAAGGGCAGACCGAATGGGACATGTGGTCCTGCGACCCCCGTCGCTTTACGCGTTTTGCTTCCGACCAGGACTAC
TGCATCGCCAAGGGCATGGAAGTTTACGGCCACGAATATGCGATGCATTTCCCGAAACACGCCTGGCCTGCTGGTCGCAA
CAGGAAACTCTCGCCGATCCATGATCGGATCGCAGCACTTGGTGCGCAATTCAAGTCCTATAATGGCTGGGAGCGCGCCA
ACTGGTACGCCAAATCAGGCGATGACACGTCGGAACAATCAACGCAGACCTGGAATCGGGCGGGGCCGTGGCAGAAACGG
ATCGAGGAGGAATGCCTGGCAGTGCGTGATGCTGCGGGCATTCTCGATCTGCCGGGCTTTTCCCGCTACCGTCTGCAGGG
TGAGGGCGCGCGCGACTGGCTGCTCGGCCTGATCACCGGCAAGGTGCCGAAACCCGGCCGCATCGGACTTGCCTATTTTG
CCGACGACAAAGGCCGTATCGTCACCGAAATGTCGGTGATGGCGCTGGAAGAGAATCTTTTCTTCCTGACCACCGCGGCG
ACAGCGCAATGGCACGATTTCGCATGGTTGCAGAAGCATCTGCCGAAAGACGCGAGTTTCACGCTCGACGATGTGACGGA
CAATTTGGCCTGCCAGATACTGTCAGGGCCGCAATCGCGTGCCATCCTCGCAGAAGTCACCGATGCCGATCTTTCCAAGC
CGTGGCTGACGCACCTGTCCTGCCAGATAGCAGGCCGCCGGCTGCAGCTGGTGCGCGTTTCCTTCGTCGGCGAGCTTGGC
TGGGAGCTTCACACGGAGATGGACGACACGGCCACGGTCTTCGACGCGGTCTGGGCTGCAGGCGGAAAGCATGGCCTGAA
GCCATTCGGCATGGAAGCACTCGACAGCCTGCGTATCGAGAAGGGCTACCGCGCCTGGAAGGGCGACCTTTCGACCGATT
ACACCATGCTGCAGGGCGGGCTAGAGCGTTTCGTCGACTGGGCAAAGCCCGATTTCAAGGGCAAGGCGGCGCTTGCGCGC
GAGAAGCAGCAAGGTGTGACGAAGCGCTTCGTCACATTGGCTGTCGAGGCCGGCGAATGTGACGCCCCCTATATGTCGAC
GCTCTGGCGCGACGGTCAGTTGGTCGGAGAGACAACGTCGGGCAACTGGGGCTACCGCGTCGGCAAGTCCGTGGCGCTCG
GCATGCTGCGGTCGGATCTGGCGGTGCCGGGCACGGAGCTGGAGGTTGAAATCTTCGGCGACCGGTTCAAGGCCGTCGTC
CAGCCCGACCGCCCGTTGTGGGATCCCGAGAACGAGAGGCTGCGAGCATGA

Upstream 100 bases:

>100_bases
TGGCATTATCTAATCGAATTCTTCGATCAATAAAGCAAGTTCCCTCCGCTTGATGCCGCTCCCGTTCGTTGCCACACTTC
CCTTCGAACGAGGAGCAGCC

Downstream 100 bases:

>100_bases
CGAAACCCATCCCCCAAAAGGCACGCGCGGTGATCATCGGCGGCGGGGTCTCAGGCTGTTCCATCGCCTACCATCTGGCG
AAGCTTGGCTGGACCGATGT

Product: FAD dependent oxidoreductase

Products: NA

Alternate protein names: Glycine cleavage system T protein [H]

Number of amino acids: Translated: 816; Mature: 815

Protein sequence:

>816_residues
MSNLPSQARVVIIGGGAVGVSALYHLAMAGWTDAVLLEKNELTAGSTWHAAGNVPTFSSSWSIMNMQRYSASLYRELGAQ
VDYPMNYHVTGSIRLGHSNERLQEFKRVVGMGRYQGMDLDILSPDQIKSKYPFVETHDLIGALHDPHDGDIDPAQLTQAL
AKGARDLGARIFRFCAAIGARRENNEWIVSTPDGDIRCEYVVNAAGYYAREVGKWFGREVPMMVMSHQYMLFEEIPELAA
WSKEAGHKLPLLRDVDSSYYLRQEKTGMNLGPYERNCKAHWLTPEDPMPEDFSFQLFPDDLERLEWYLNDAVERVPILGT
AGLSRMINGPIPYTPDGNPLIGPMPGVPNAFEACVFTFGICQAGGAGKVLAEWLTEGQTEWDMWSCDPRRFTRFASDQDY
CIAKGMEVYGHEYAMHFPKHAWPAGRNRKLSPIHDRIAALGAQFKSYNGWERANWYAKSGDDTSEQSTQTWNRAGPWQKR
IEEECLAVRDAAGILDLPGFSRYRLQGEGARDWLLGLITGKVPKPGRIGLAYFADDKGRIVTEMSVMALEENLFFLTTAA
TAQWHDFAWLQKHLPKDASFTLDDVTDNLACQILSGPQSRAILAEVTDADLSKPWLTHLSCQIAGRRLQLVRVSFVGELG
WELHTEMDDTATVFDAVWAAGGKHGLKPFGMEALDSLRIEKGYRAWKGDLSTDYTMLQGGLERFVDWAKPDFKGKAALAR
EKQQGVTKRFVTLAVEAGECDAPYMSTLWRDGQLVGETTSGNWGYRVGKSVALGMLRSDLAVPGTELEVEIFGDRFKAVV
QPDRPLWDPENERLRA

Sequences:

>Translated_816_residues
MSNLPSQARVVIIGGGAVGVSALYHLAMAGWTDAVLLEKNELTAGSTWHAAGNVPTFSSSWSIMNMQRYSASLYRELGAQ
VDYPMNYHVTGSIRLGHSNERLQEFKRVVGMGRYQGMDLDILSPDQIKSKYPFVETHDLIGALHDPHDGDIDPAQLTQAL
AKGARDLGARIFRFCAAIGARRENNEWIVSTPDGDIRCEYVVNAAGYYAREVGKWFGREVPMMVMSHQYMLFEEIPELAA
WSKEAGHKLPLLRDVDSSYYLRQEKTGMNLGPYERNCKAHWLTPEDPMPEDFSFQLFPDDLERLEWYLNDAVERVPILGT
AGLSRMINGPIPYTPDGNPLIGPMPGVPNAFEACVFTFGICQAGGAGKVLAEWLTEGQTEWDMWSCDPRRFTRFASDQDY
CIAKGMEVYGHEYAMHFPKHAWPAGRNRKLSPIHDRIAALGAQFKSYNGWERANWYAKSGDDTSEQSTQTWNRAGPWQKR
IEEECLAVRDAAGILDLPGFSRYRLQGEGARDWLLGLITGKVPKPGRIGLAYFADDKGRIVTEMSVMALEENLFFLTTAA
TAQWHDFAWLQKHLPKDASFTLDDVTDNLACQILSGPQSRAILAEVTDADLSKPWLTHLSCQIAGRRLQLVRVSFVGELG
WELHTEMDDTATVFDAVWAAGGKHGLKPFGMEALDSLRIEKGYRAWKGDLSTDYTMLQGGLERFVDWAKPDFKGKAALAR
EKQQGVTKRFVTLAVEAGECDAPYMSTLWRDGQLVGETTSGNWGYRVGKSVALGMLRSDLAVPGTELEVEIFGDRFKAVV
QPDRPLWDPENERLRA
>Mature_815_residues
SNLPSQARVVIIGGGAVGVSALYHLAMAGWTDAVLLEKNELTAGSTWHAAGNVPTFSSSWSIMNMQRYSASLYRELGAQV
DYPMNYHVTGSIRLGHSNERLQEFKRVVGMGRYQGMDLDILSPDQIKSKYPFVETHDLIGALHDPHDGDIDPAQLTQALA
KGARDLGARIFRFCAAIGARRENNEWIVSTPDGDIRCEYVVNAAGYYAREVGKWFGREVPMMVMSHQYMLFEEIPELAAW
SKEAGHKLPLLRDVDSSYYLRQEKTGMNLGPYERNCKAHWLTPEDPMPEDFSFQLFPDDLERLEWYLNDAVERVPILGTA
GLSRMINGPIPYTPDGNPLIGPMPGVPNAFEACVFTFGICQAGGAGKVLAEWLTEGQTEWDMWSCDPRRFTRFASDQDYC
IAKGMEVYGHEYAMHFPKHAWPAGRNRKLSPIHDRIAALGAQFKSYNGWERANWYAKSGDDTSEQSTQTWNRAGPWQKRI
EEECLAVRDAAGILDLPGFSRYRLQGEGARDWLLGLITGKVPKPGRIGLAYFADDKGRIVTEMSVMALEENLFFLTTAAT
AQWHDFAWLQKHLPKDASFTLDDVTDNLACQILSGPQSRAILAEVTDADLSKPWLTHLSCQIAGRRLQLVRVSFVGELGW
ELHTEMDDTATVFDAVWAAGGKHGLKPFGMEALDSLRIEKGYRAWKGDLSTDYTMLQGGLERFVDWAKPDFKGKAALARE
KQQGVTKRFVTLAVEAGECDAPYMSTLWRDGQLVGETTSGNWGYRVGKSVALGMLRSDLAVPGTELEVEIFGDRFKAVVQ
PDRPLWDPENERLRA

Specific function: The glycine cleavage system catalyzes the degradation of glycine [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the gcvT family [H]

Homologues:

Organism=Homo sapiens, GI24797151, Length=822, Percent_Identity=35.7664233576642, Blast_Score=521, Evalue=1e-147,
Organism=Homo sapiens, GI197927446, Length=870, Percent_Identity=32.183908045977, Blast_Score=422, Evalue=1e-118,
Organism=Homo sapiens, GI21361378, Length=870, Percent_Identity=32.183908045977, Blast_Score=422, Evalue=1e-118,
Organism=Homo sapiens, GI194306651, Length=827, Percent_Identity=29.8669891172914, Blast_Score=344, Evalue=2e-94,
Organism=Homo sapiens, GI44662838, Length=407, Percent_Identity=23.5872235872236, Blast_Score=80, Evalue=1e-14,
Organism=Homo sapiens, GI257796258, Length=394, Percent_Identity=23.3502538071066, Blast_Score=78, Evalue=3e-14,
Organism=Homo sapiens, GI257796256, Length=314, Percent_Identity=24.8407643312102, Blast_Score=71, Evalue=5e-12,
Organism=Escherichia coli, GI1789272, Length=357, Percent_Identity=23.8095238095238, Blast_Score=80, Evalue=4e-16,
Organism=Caenorhabditis elegans, GI71994045, Length=831, Percent_Identity=27.4368231046931, Blast_Score=272, Evalue=6e-73,
Organism=Caenorhabditis elegans, GI71994052, Length=838, Percent_Identity=27.0883054892601, Blast_Score=268, Evalue=9e-72,
Organism=Caenorhabditis elegans, GI32563613, Length=854, Percent_Identity=28.1030444964871, Blast_Score=268, Evalue=1e-71,
Organism=Caenorhabditis elegans, GI17560118, Length=349, Percent_Identity=24.3553008595989, Blast_Score=76, Evalue=8e-14,
Organism=Drosophila melanogaster, GI20130091, Length=873, Percent_Identity=29.7823596792669, Blast_Score=363, Evalue=1e-100,
Organism=Drosophila melanogaster, GI28571104, Length=852, Percent_Identity=29.1079812206573, Blast_Score=322, Evalue=5e-88,
Organism=Drosophila melanogaster, GI20129441, Length=332, Percent_Identity=24.0963855421687, Blast_Score=76, Evalue=9e-14,

Paralogues:

None

Copy number: 40 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013977
- InterPro:   IPR006222
- InterPro:   IPR006223
- InterPro:   IPR022903 [H]

Pfam domain/function: PF01571 GCV_T; PF08669 GCV_T_C [H]

EC number: =2.1.2.10 [H]

Molecular weight: Translated: 91282; Mature: 91151

Theoretical pI: Translated: 5.47; Mature: 5.47

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSNLPSQARVVIIGGGAVGVSALYHLAMAGWTDAVLLEKNELTAGSTWHAAGNVPTFSSS
CCCCCCCCEEEEEECCHHHHHHHHHHHHHCCCCEEEEECCCCCCCCCEECCCCCCCCCCC
WSIMNMQRYSASLYRELGAQVDYPMNYHVTGSIRLGHSNERLQEFKRVVGMGRYQGMDLD
CCEEHHHHHHHHHHHHHCCCCCCCCEEEEEEEEEECCCHHHHHHHHHHHCCCCCCCCCEE
ILSPDQIKSKYPFVETHDLIGALHDPHDGDIDPAQLTQALAKGARDLGARIFRFCAAIGA
CCCHHHHHCCCCCEEHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCC
RRENNEWIVSTPDGDIRCEYVVNAAGYYAREVGKWFGREVPMMVMSHQYMLFEEIPELAA
CCCCCCEEEECCCCCEEEEEEECCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHH
WSKEAGHKLPLLRDVDSSYYLRQEKTGMNLGPYERNCKAHWLTPEDPMPEDFSFQLFPDD
HHHHCCCCCCEEEECCCCCEEEHHCCCCCCCCCCCCCEEEECCCCCCCCCCCEEEECHHH
LERLEWYLNDAVERVPILGTAGLSRMINGPIPYTPDGNPLIGPMPGVPNAFEACVFTFGI
HHHHHHHHHHHHHHCCCEEHHHHHHHHCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHH
CQAGGAGKVLAEWLTEGQTEWDMWSCDPRRFTRFASDQDYCIAKGMEVYGHEYAMHFPKH
HCCCCCHHHHHHHHHCCCCCCCCCCCCHHHHHHHCCCCCCHHHCCHHHHCCHHHCCCCCC
AWPAGRNRKLSPIHDRIAALGAQFKSYNGWERANWYAKSGDDTSEQSTQTWNRAGPWQKR
CCCCCCCCCCCHHHHHHHHHHHHHHCCCCCHHCCCEECCCCCCCHHHHHHHHCCCHHHHH
IEEECLAVRDAAGILDLPGFSRYRLQGEGARDWLLGLITGKVPKPGRIGLAYFADDKGRI
HHHHHHHHHHCCCCEECCCCCEEEECCCCCHHHHHHHHCCCCCCCCCEEEEEEECCCCCE
VTEMSVMALEENLFFLTTAATAQWHDFAWLQKHLPKDASFTLDDVTDNLACQILSGPQSR
EEHHHHHHEECCEEEEEEECCCCHHHHHHHHHHCCCCCCEEHHHHCCCCEEEEECCCCCC
AILAEVTDADLSKPWLTHLSCQIAGRRLQLVRVSFVGELGWELHTEMDDTATVFDAVWAA
EEEEEECCCCCCCHHHHHHHHHCCCCEEEEEEEEHHHHCCCCEECCCCCHHHHHHHHHHC
GGKHGLKPFGMEALDSLRIEKGYRAWKGDLSTDYTMLQGGLERFVDWAKPDFKGKAALAR
CCCCCCCCCCHHHHHHHHHHCCCHHHCCCCCCCHHHHHHHHHHHHHHCCCCCCCCHHHHH
EKQQGVTKRFVTLAVEAGECDAPYMSTLWRDGQLVGETTSGNWGYRVGKSVALGMLRSDL
HHHHHHHEEEEEEEEECCCCCCHHHHHHHCCCEEEEECCCCCCCCHHHHHHHHHHHHHHC
AVPGTELEVEIFGDRFKAVVQPDRPLWDPENERLRA
CCCCCEEEEEEECCHHHEEECCCCCCCCCCCCCCCC
>Mature Secondary Structure 
SNLPSQARVVIIGGGAVGVSALYHLAMAGWTDAVLLEKNELTAGSTWHAAGNVPTFSSS
CCCCCCCEEEEEECCHHHHHHHHHHHHHCCCCEEEEECCCCCCCCCEECCCCCCCCCCC
WSIMNMQRYSASLYRELGAQVDYPMNYHVTGSIRLGHSNERLQEFKRVVGMGRYQGMDLD
CCEEHHHHHHHHHHHHHCCCCCCCCEEEEEEEEEECCCHHHHHHHHHHHCCCCCCCCCEE
ILSPDQIKSKYPFVETHDLIGALHDPHDGDIDPAQLTQALAKGARDLGARIFRFCAAIGA
CCCHHHHHCCCCCEEHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCC
RRENNEWIVSTPDGDIRCEYVVNAAGYYAREVGKWFGREVPMMVMSHQYMLFEEIPELAA
CCCCCCEEEECCCCCEEEEEEECCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHH
WSKEAGHKLPLLRDVDSSYYLRQEKTGMNLGPYERNCKAHWLTPEDPMPEDFSFQLFPDD
HHHHCCCCCCEEEECCCCCEEEHHCCCCCCCCCCCCCEEEECCCCCCCCCCCEEEECHHH
LERLEWYLNDAVERVPILGTAGLSRMINGPIPYTPDGNPLIGPMPGVPNAFEACVFTFGI
HHHHHHHHHHHHHHCCCEEHHHHHHHHCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHH
CQAGGAGKVLAEWLTEGQTEWDMWSCDPRRFTRFASDQDYCIAKGMEVYGHEYAMHFPKH
HCCCCCHHHHHHHHHCCCCCCCCCCCCHHHHHHHCCCCCCHHHCCHHHHCCHHHCCCCCC
AWPAGRNRKLSPIHDRIAALGAQFKSYNGWERANWYAKSGDDTSEQSTQTWNRAGPWQKR
CCCCCCCCCCCHHHHHHHHHHHHHHCCCCCHHCCCEECCCCCCCHHHHHHHHCCCHHHHH
IEEECLAVRDAAGILDLPGFSRYRLQGEGARDWLLGLITGKVPKPGRIGLAYFADDKGRI
HHHHHHHHHHCCCCEECCCCCEEEECCCCCHHHHHHHHCCCCCCCCCEEEEEEECCCCCE
VTEMSVMALEENLFFLTTAATAQWHDFAWLQKHLPKDASFTLDDVTDNLACQILSGPQSR
EEHHHHHHEECCEEEEEEECCCCHHHHHHHHHHCCCCCCEEHHHHCCCCEEEEECCCCCC
AILAEVTDADLSKPWLTHLSCQIAGRRLQLVRVSFVGELGWELHTEMDDTATVFDAVWAA
EEEEEECCCCCCCHHHHHHHHHCCCCEEEEEEEEHHHHCCCCEECCCCCHHHHHHHHHHC
GGKHGLKPFGMEALDSLRIEKGYRAWKGDLSTDYTMLQGGLERFVDWAKPDFKGKAALAR
CCCCCCCCCCHHHHHHHHHHCCCHHHCCCCCCCHHHHHHHHHHHHHHCCCCCCCCHHHHH
EKQQGVTKRFVTLAVEAGECDAPYMSTLWRDGQLVGETTSGNWGYRVGKSVALGMLRSDL
HHHHHHHEEEEEEEEECCCCCCHHHHHHHCCCEEEEECCCCCCCCHHHHHHHHHHHHHHC
AVPGTELEVEIFGDRFKAVVQPDRPLWDPENERLRA
CCCCCEEEEEEECCHHHEEECCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA