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The map label for this gene is gcvT [H]

Identifier: 209550887

GI number: 209550887

Start: 3402057

End: 3404510

Strand: Direct

Name: gcvT [H]

Synonym: Rleg2_3311

Alternate gene names: 209550887

Gene position: 3402057-3404510 (Clockwise)

Preceding gene: 209550886

Following gene: 209550888

Centisome position: 74.97

GC content: 61.17

Gene sequence:

>2454_bases
ATGACGAAACCCATCCCCCAAAAGGCACGCGCGGTGATCATCGGCGGCGGGGTCTCAGGCTGTTCCATCGCCTACCATCT
GGCGAAGCTTGGCTGGACCGATGTCGTACTGCTCGAACGCAAACAGCTCACCTCCGGCACCACATGGCATGCGGCCGGCC
TCATCGGTCAGCTCCGCGCCTCGCAAAACATGACGCGCCTCGCCAAATATTCCGCCGATCTCTACGTCAGGCTGGAGGCC
GAAACCGGCATCGGCACCGGCATGCGCCAAAATGGCTCGATCACCGTTGCCCTGACCGAAGAGCGTAAGGAAGAGATCTA
CCGTCAGGCCTCGCTGGCCCGGGCGTTCAAAATCGACGTTCGCGAGATTTCGCCGGAAGAGGCGAAGGCGCTTTACCCGC
ATCTCAACATCGGCGACATCAAGGCAGCGGTTCACCTGCCGCTCGACGGACAATGCGACCCGGCAAACATCGCCATGGCG
CTCGCCAAGGGAGCTCGGCAGCACGGTGCGACCATCATCGAAGGCGTAAAGGTCATCGAGGTGCTTGCCAGGGATGGGCG
AGTCGTCGGCGTCGTCTGCGAACAGGCCGGCGAGCGTTTCACGATCGAGACGGAAAATGTCGTCAACGCCGCCGGCATGT
GGGGCAGAGATCTCGCTCGGCAATCCGGCGTCACCTTGCCGCTGCATGCCTGCGAGCATTTCTACATTGTCACCGAGCCG
GTTGGGGGGCTGAAGTCTCTGCCTGTGCTGCGTGTGCCGGACGAGTGTGCCTATTACAAGGAAGATGCCGGCAAGATGCT
CATTGGCGCCTTCGAGCCGGTCGCCAAGCCCTGGCCGCCGGCGGGCGAGGCAATCCGCGAGGACTTCTGCTTCGACCAAT
TGCCAGAGGATTTCGACCACTTCCAGCCGATCCTTGAAATGGCGATCAACCGGATGCCGATGCTGGAAACTGCCGGCATC
CACACCTTCTTCAATGGACCGGAGAGCTTTACGCCCGACGATCGCTATTATCTAGGCGAGGCGCCGGAACTGACAGGGTA
TTGGGTGGCGGCCGGATATAATTCGATCGGCATCGTATCTTCTGGCGGCGCCGGTATGGCGCTTGCCCAATGGATGAACG
ACGGCGAACCGCCCTTCGATCTCTGGGATGTAGACATCCGCCGCGCCCAGCCCTTCCAGAGAAACCGGCTCTACCTGAAG
GACAGAGTCACAGAGACGCTCGGCCTGCTTTACGCGGACCATTTCCCATATCGGCAGATGGCGACCGCGCGCGGTATACG
CCGCTCGCCGATCCATGAGCACCTTGCGGCGCGTGGCGCCGTGTTCGGCGAAGTGGCTGGCTGGGAGCGCGCCAACTGGT
TTGCCAGGGAAGGGCAAGAGCGGGAATACCAGTATAGCTGGCGGCGACAGAACTGGTTTGAAAACCAACGCGAGGAACAT
CTGGCAATCCGGACCGGCGTCGGTCTCTTCGACATGACCTCCTTTGGGAAAATCCGGGTCGAAGGGCGAGACGCCTGTCG
CTTCCTGCAACGGCTCTGCGCCAACCAGATAGACGTGCCCGCCGGCCGGATCGTCTATACGCAGATGTTGAACCATCGTG
GCGGCATCGAAAGTGACCTCACCGCAACCCGGCTGACCGAAACCGCCTTCCTGCTCATTGTTCCAGGTGCGACGCTGCAG
CGTGATCTTGCCTGGTTGCGCAGGCACGTGGCAGATGAAAATGTCGTTGTTACCGATATGACGGCCGCCGAAAGCGTGCT
CTGCGTGATGGGTCCGGAGTCGCGTCAGCTGATGCAGAGGGTCAGCCCAGACGATTTCTCCAACGACGCCCATCCCTTCG
CCACTGCGCGGGAAATCGAGATCGGCATGGGACTGGCTCGCGCTCACCGCGTCACCTATGTCGGCGAACTCGGCTGGGAG
CTCTATATCTCTACCGACCAGGCCGCCCACGTTTTTGAGGCGCTGGAACTGGCCGGCCTGGACCTCGGTCTGAAGCTTTG
CGGCATCCACACGCTCGATAGCTGCCGCATCGAAAAGGGGTTCCGCCATTTCGGCCATGACATTACCGATGAGGATCATG
TGCTGGAAGCAGGCCTCGGCTTCGCCGTCAAAACCGGCCAAGGGGAGTTTATCGGCCGCGATGCCGTCTTGCACAAGCAG
GAAACGGGCGTTGATCGCCGGCTGGTGCAATTCAAGCTCACAGATCCTGAACCGTTGCTCTTTCACAACGAGGTGATCGT
CCGCGACGGAGAGATCGTCGGCACCATAACCTCCGGCAACTACGGCCACTTCCTCGGCGGTGCGATCGGGCTGGGTTACG
TGCCCTGTGAGGGTGAGAGCGCGGCGGAAGTGCTTGGCTCATTTTACGAAATCGAGATTGCGGGAACGAGGGTGAGAGCC
GAGCCGTCACTTGCGCCGATGTATGACCCGAATGCCGCGAGGGTTCGGATGTGA

Upstream 100 bases:

>100_bases
CGGGCACGGAGCTGGAGGTTGAAATCTTCGGCGACCGGTTCAAGGCCGTCGTCCAGCCCGACCGCCCGTTGTGGGATCCC
GAGAACGAGAGGCTGCGAGC

Downstream 100 bases:

>100_bases
CAACGGACATGTCGGTATTTGCAACTGCTGCGCCATCGGTCGACTGCATCGATCAGCTCATTGCTGCTCACAAGCCGGGC
CACGGTCTTGCCCGGCCATT

Product: FAD dependent oxidoreductase

Products: NA

Alternate protein names: Glycine cleavage system T protein [H]

Number of amino acids: Translated: 817; Mature: 816

Protein sequence:

>817_residues
MTKPIPQKARAVIIGGGVSGCSIAYHLAKLGWTDVVLLERKQLTSGTTWHAAGLIGQLRASQNMTRLAKYSADLYVRLEA
ETGIGTGMRQNGSITVALTEERKEEIYRQASLARAFKIDVREISPEEAKALYPHLNIGDIKAAVHLPLDGQCDPANIAMA
LAKGARQHGATIIEGVKVIEVLARDGRVVGVVCEQAGERFTIETENVVNAAGMWGRDLARQSGVTLPLHACEHFYIVTEP
VGGLKSLPVLRVPDECAYYKEDAGKMLIGAFEPVAKPWPPAGEAIREDFCFDQLPEDFDHFQPILEMAINRMPMLETAGI
HTFFNGPESFTPDDRYYLGEAPELTGYWVAAGYNSIGIVSSGGAGMALAQWMNDGEPPFDLWDVDIRRAQPFQRNRLYLK
DRVTETLGLLYADHFPYRQMATARGIRRSPIHEHLAARGAVFGEVAGWERANWFAREGQEREYQYSWRRQNWFENQREEH
LAIRTGVGLFDMTSFGKIRVEGRDACRFLQRLCANQIDVPAGRIVYTQMLNHRGGIESDLTATRLTETAFLLIVPGATLQ
RDLAWLRRHVADENVVVTDMTAAESVLCVMGPESRQLMQRVSPDDFSNDAHPFATAREIEIGMGLARAHRVTYVGELGWE
LYISTDQAAHVFEALELAGLDLGLKLCGIHTLDSCRIEKGFRHFGHDITDEDHVLEAGLGFAVKTGQGEFIGRDAVLHKQ
ETGVDRRLVQFKLTDPEPLLFHNEVIVRDGEIVGTITSGNYGHFLGGAIGLGYVPCEGESAAEVLGSFYEIEIAGTRVRA
EPSLAPMYDPNAARVRM

Sequences:

>Translated_817_residues
MTKPIPQKARAVIIGGGVSGCSIAYHLAKLGWTDVVLLERKQLTSGTTWHAAGLIGQLRASQNMTRLAKYSADLYVRLEA
ETGIGTGMRQNGSITVALTEERKEEIYRQASLARAFKIDVREISPEEAKALYPHLNIGDIKAAVHLPLDGQCDPANIAMA
LAKGARQHGATIIEGVKVIEVLARDGRVVGVVCEQAGERFTIETENVVNAAGMWGRDLARQSGVTLPLHACEHFYIVTEP
VGGLKSLPVLRVPDECAYYKEDAGKMLIGAFEPVAKPWPPAGEAIREDFCFDQLPEDFDHFQPILEMAINRMPMLETAGI
HTFFNGPESFTPDDRYYLGEAPELTGYWVAAGYNSIGIVSSGGAGMALAQWMNDGEPPFDLWDVDIRRAQPFQRNRLYLK
DRVTETLGLLYADHFPYRQMATARGIRRSPIHEHLAARGAVFGEVAGWERANWFAREGQEREYQYSWRRQNWFENQREEH
LAIRTGVGLFDMTSFGKIRVEGRDACRFLQRLCANQIDVPAGRIVYTQMLNHRGGIESDLTATRLTETAFLLIVPGATLQ
RDLAWLRRHVADENVVVTDMTAAESVLCVMGPESRQLMQRVSPDDFSNDAHPFATAREIEIGMGLARAHRVTYVGELGWE
LYISTDQAAHVFEALELAGLDLGLKLCGIHTLDSCRIEKGFRHFGHDITDEDHVLEAGLGFAVKTGQGEFIGRDAVLHKQ
ETGVDRRLVQFKLTDPEPLLFHNEVIVRDGEIVGTITSGNYGHFLGGAIGLGYVPCEGESAAEVLGSFYEIEIAGTRVRA
EPSLAPMYDPNAARVRM
>Mature_816_residues
TKPIPQKARAVIIGGGVSGCSIAYHLAKLGWTDVVLLERKQLTSGTTWHAAGLIGQLRASQNMTRLAKYSADLYVRLEAE
TGIGTGMRQNGSITVALTEERKEEIYRQASLARAFKIDVREISPEEAKALYPHLNIGDIKAAVHLPLDGQCDPANIAMAL
AKGARQHGATIIEGVKVIEVLARDGRVVGVVCEQAGERFTIETENVVNAAGMWGRDLARQSGVTLPLHACEHFYIVTEPV
GGLKSLPVLRVPDECAYYKEDAGKMLIGAFEPVAKPWPPAGEAIREDFCFDQLPEDFDHFQPILEMAINRMPMLETAGIH
TFFNGPESFTPDDRYYLGEAPELTGYWVAAGYNSIGIVSSGGAGMALAQWMNDGEPPFDLWDVDIRRAQPFQRNRLYLKD
RVTETLGLLYADHFPYRQMATARGIRRSPIHEHLAARGAVFGEVAGWERANWFAREGQEREYQYSWRRQNWFENQREEHL
AIRTGVGLFDMTSFGKIRVEGRDACRFLQRLCANQIDVPAGRIVYTQMLNHRGGIESDLTATRLTETAFLLIVPGATLQR
DLAWLRRHVADENVVVTDMTAAESVLCVMGPESRQLMQRVSPDDFSNDAHPFATAREIEIGMGLARAHRVTYVGELGWEL
YISTDQAAHVFEALELAGLDLGLKLCGIHTLDSCRIEKGFRHFGHDITDEDHVLEAGLGFAVKTGQGEFIGRDAVLHKQE
TGVDRRLVQFKLTDPEPLLFHNEVIVRDGEIVGTITSGNYGHFLGGAIGLGYVPCEGESAAEVLGSFYEIEIAGTRVRAE
PSLAPMYDPNAARVRM

Specific function: The glycine cleavage system catalyzes the degradation of glycine [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the gcvT family [H]

Homologues:

Organism=Homo sapiens, GI197927446, Length=865, Percent_Identity=36.1849710982659, Blast_Score=510, Evalue=1e-144,
Organism=Homo sapiens, GI21361378, Length=865, Percent_Identity=36.1849710982659, Blast_Score=510, Evalue=1e-144,
Organism=Homo sapiens, GI194306651, Length=827, Percent_Identity=36.2756952841596, Blast_Score=480, Evalue=1e-135,
Organism=Homo sapiens, GI24797151, Length=827, Percent_Identity=32.6481257557436, Blast_Score=425, Evalue=1e-119,
Organism=Homo sapiens, GI257796258, Length=360, Percent_Identity=24.7222222222222, Blast_Score=108, Evalue=2e-23,
Organism=Homo sapiens, GI44662838, Length=360, Percent_Identity=24.7222222222222, Blast_Score=108, Evalue=3e-23,
Organism=Homo sapiens, GI257796256, Length=292, Percent_Identity=25.3424657534247, Blast_Score=94, Evalue=5e-19,
Organism=Homo sapiens, GI257796254, Length=356, Percent_Identity=23.876404494382, Blast_Score=84, Evalue=6e-16,
Organism=Escherichia coli, GI1789272, Length=328, Percent_Identity=28.3536585365854, Blast_Score=119, Evalue=6e-28,
Organism=Caenorhabditis elegans, GI32563613, Length=849, Percent_Identity=33.4511189634865, Blast_Score=365, Evalue=1e-101,
Organism=Caenorhabditis elegans, GI71994045, Length=794, Percent_Identity=30.1007556675063, Blast_Score=309, Evalue=5e-84,
Organism=Caenorhabditis elegans, GI71994052, Length=801, Percent_Identity=29.8377028714107, Blast_Score=305, Evalue=5e-83,
Organism=Caenorhabditis elegans, GI17560118, Length=345, Percent_Identity=23.1884057971014, Blast_Score=82, Evalue=1e-15,
Organism=Saccharomyces cerevisiae, GI6320222, Length=346, Percent_Identity=23.9884393063584, Blast_Score=75, Evalue=3e-14,
Organism=Drosophila melanogaster, GI28571104, Length=838, Percent_Identity=33.5322195704057, Blast_Score=439, Evalue=1e-123,
Organism=Drosophila melanogaster, GI20130091, Length=862, Percent_Identity=32.5986078886311, Blast_Score=407, Evalue=1e-113,
Organism=Drosophila melanogaster, GI20129441, Length=308, Percent_Identity=28.2467532467532, Blast_Score=107, Evalue=4e-23,

Paralogues:

None

Copy number: 40 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013977
- InterPro:   IPR006222
- InterPro:   IPR006223
- InterPro:   IPR022903 [H]

Pfam domain/function: PF01571 GCV_T; PF08669 GCV_T_C [H]

EC number: =2.1.2.10 [H]

Molecular weight: Translated: 90531; Mature: 90400

Theoretical pI: Translated: 5.61; Mature: 5.61

Prosite motif: PS00013 PROKAR_LIPOPROTEIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTKPIPQKARAVIIGGGVSGCSIAYHLAKLGWTDVVLLERKQLTSGTTWHAAGLIGQLRA
CCCCCCCCCCEEEEECCCCHHHHHHHHHHCCCCEEEEEEHHHCCCCCCCHHHHHHHHHHH
SQNMTRLAKYSADLYVRLEAETGIGTGMRQNGSITVALTEERKEEIYRQASLARAFKIDV
HCCHHHHHHCCCEEEEEEEECCCCCCCCCCCCCEEEEECHHHHHHHHHHHHHHHHHEEEH
REISPEEAKALYPHLNIGDIKAAVHLPLDGQCDPANIAMALAKGARQHGATIIEGVKVIE
HHCCCHHHHHHCCCCCCCCEEEEEECCCCCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHH
VLARDGRVVGVVCEQAGERFTIETENVVNAAGMWGRDLARQSGVTLPLHACEHFYIVTEP
HHHCCCCEEEEEECCCCCEEEEECCCHHHHCCCCHHHHHHHCCCEEEEECCCEEEEEECC
VGGLKSLPVLRVPDECAYYKEDAGKMLIGAFEPVAKPWPPAGEAIREDFCFDQLPEDFDH
CCCHHCCCEEECCHHHHHHHHCCCCEEEECCCCCCCCCCCCHHHHHHHHHHHHCCHHHHH
FQPILEMAINRMPMLETAGIHTFFNGPESFTPDDRYYLGEAPELTGYWVAAGYNSIGIVS
HHHHHHHHHCCCCCCHHCCCEEEECCCCCCCCCCCEEECCCCCCCEEEEEECCCCEEEEE
SGGAGMALAQWMNDGEPPFDLWDVDIRRAQPFQRNRLYLKDRVTETLGLLYADHFPYRQM
CCCCCHHHHHHHCCCCCCCCEEECCHHHCCCCHHCCEEHHHHHHHHHHHHHHCCCCHHHH
ATARGIRRSPIHEHLAARGAVFGEVAGWERANWFAREGQEREYQYSWRRQNWFENQREEH
HHHCCCCCCHHHHHHHHCCCHHHHHCCCCHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHH
LAIRTGVGLFDMTSFGKIRVEGRDACRFLQRLCANQIDVPAGRIVYTQMLNHRGGIESDL
EEEEECCCEEECCCCCEEEECCHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHCCCCCCCC
TATRLTETAFLLIVPGATLQRDLAWLRRHVADENVVVTDMTAAESVLCVMGPESRQLMQR
HHHHHCCEEEEEEECCCHHHHHHHHHHHHHCCCCEEEEECCCCCCEEEEECCCHHHHHHH
VSPDDFSNDAHPFATAREIEIGMGLARAHRVTYVGELGWELYISTDQAAHVFEALELAGL
CCCCCCCCCCCCCCEEEEEECCCCHHHHHHEEEEECCCEEEEEECCHHHHHHHHHHHCCC
DLGLKLCGIHTLDSCRIEKGFRHFGHDITDEDHVLEAGLGFAVKTGQGEFIGRDAVLHKQ
CCCEEEECCCCCCHHHHHHHHHHHCCCCCCCCHHHHCCCCEEEECCCCCEECCHHHHCCH
ETGVDRRLVQFKLTDPEPLLFHNEVIVRDGEIVGTITSGNYGHFLGGAIGLGYVPCEGES
HCCCCEEEEEEEECCCCCEEEECEEEEECCEEEEEEECCCCCHHHHHHHCCCEECCCCCH
AAEVLGSFYEIEIAGTRVRAEPSLAPMYDPNAARVRM
HHHHCCCEEEEEEECCEEECCCCCCCCCCCCCCEECC
>Mature Secondary Structure 
TKPIPQKARAVIIGGGVSGCSIAYHLAKLGWTDVVLLERKQLTSGTTWHAAGLIGQLRA
CCCCCCCCCEEEEECCCCHHHHHHHHHHCCCCEEEEEEHHHCCCCCCCHHHHHHHHHHH
SQNMTRLAKYSADLYVRLEAETGIGTGMRQNGSITVALTEERKEEIYRQASLARAFKIDV
HCCHHHHHHCCCEEEEEEEECCCCCCCCCCCCCEEEEECHHHHHHHHHHHHHHHHHEEEH
REISPEEAKALYPHLNIGDIKAAVHLPLDGQCDPANIAMALAKGARQHGATIIEGVKVIE
HHCCCHHHHHHCCCCCCCCEEEEEECCCCCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHH
VLARDGRVVGVVCEQAGERFTIETENVVNAAGMWGRDLARQSGVTLPLHACEHFYIVTEP
HHHCCCCEEEEEECCCCCEEEEECCCHHHHCCCCHHHHHHHCCCEEEEECCCEEEEEECC
VGGLKSLPVLRVPDECAYYKEDAGKMLIGAFEPVAKPWPPAGEAIREDFCFDQLPEDFDH
CCCHHCCCEEECCHHHHHHHHCCCCEEEECCCCCCCCCCCCHHHHHHHHHHHHCCHHHHH
FQPILEMAINRMPMLETAGIHTFFNGPESFTPDDRYYLGEAPELTGYWVAAGYNSIGIVS
HHHHHHHHHCCCCCCHHCCCEEEECCCCCCCCCCCEEECCCCCCCEEEEEECCCCEEEEE
SGGAGMALAQWMNDGEPPFDLWDVDIRRAQPFQRNRLYLKDRVTETLGLLYADHFPYRQM
CCCCCHHHHHHHCCCCCCCCEEECCHHHCCCCHHCCEEHHHHHHHHHHHHHHCCCCHHHH
ATARGIRRSPIHEHLAARGAVFGEVAGWERANWFAREGQEREYQYSWRRQNWFENQREEH
HHHCCCCCCHHHHHHHHCCCHHHHHCCCCHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHH
LAIRTGVGLFDMTSFGKIRVEGRDACRFLQRLCANQIDVPAGRIVYTQMLNHRGGIESDL
EEEEECCCEEECCCCCEEEECCHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHCCCCCCCC
TATRLTETAFLLIVPGATLQRDLAWLRRHVADENVVVTDMTAAESVLCVMGPESRQLMQR
HHHHHCCEEEEEEECCCHHHHHHHHHHHHHCCCCEEEEECCCCCCEEEEECCCHHHHHHH
VSPDDFSNDAHPFATAREIEIGMGLARAHRVTYVGELGWELYISTDQAAHVFEALELAGL
CCCCCCCCCCCCCCEEEEEECCCCHHHHHHEEEEECCCEEEEEECCHHHHHHHHHHHCCC
DLGLKLCGIHTLDSCRIEKGFRHFGHDITDEDHVLEAGLGFAVKTGQGEFIGRDAVLHKQ
CCCEEEECCCCCCHHHHHHHHHHHCCCCCCCCHHHHCCCCEEEECCCCCEECCHHHHCCH
ETGVDRRLVQFKLTDPEPLLFHNEVIVRDGEIVGTITSGNYGHFLGGAIGLGYVPCEGES
HCCCCEEEEEEEECCCCCEEEECEEEEECCEEEEEEECCCCCHHHHHHHCCCEECCCCCH
AAEVLGSFYEIEIAGTRVRAEPSLAPMYDPNAARVRM
HHHHCCCEEEEEEECCEEECCCCCCCCCCCCCCEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA